Perturb_6004_KD_CEBPZ_SRP271175 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting CEBPZ in fibroblasts BJ cell line (Study accession: SRP271175) (PerturbAtlas)
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Genes

200 genes differentially expressed following the Perturb_6004_KD_CEBPZ_SRP271175 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
CACUL1 CDK2-associated, cullin domain 1 20.0
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 20.0
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 20.0
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 20.0
TOB1 transducer of ERBB2, 1 20.0
EIF5B eukaryotic translation initiation factor 5B 20.0
CDC42 cell division cycle 42 20.0
ZNF106 zinc finger protein 106 20.0
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 20.0
COLGALT1 collagen beta(1-O)galactosyltransferase 1 20.0
NF2 neurofibromin 2 (merlin) 20.0
TACC1 transforming, acidic coiled-coil containing protein 1 20.0
TLK1 tousled-like kinase 1 20.0
ARRDC3 arrestin domain containing 3 20.0
NABP1 nucleic acid binding protein 1 20.0
SET SET nuclear proto-oncogene 20.0
SDC4 syndecan 4 20.0
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 20.0
GOLIM4 golgi integral membrane protein 4 20.0
DIO2 deiodinase, iodothyronine, type II 20.0
UBE2B ubiquitin-conjugating enzyme E2B 20.0
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 20.0
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 20.0
CRK v-crk avian sarcoma virus CT10 oncogene homolog 20.0
BICC1 BicC family RNA binding protein 1 20.0
TTC39C tetratricopeptide repeat domain 39C 20.0
PABPC1 poly(A) binding protein, cytoplasmic 1 20.0
CNTN1 contactin 1 20.0
TOR1AIP2 torsin A interacting protein 2 20.0
STRN3 striatin, calmodulin binding protein 3 20.0
RAB31 RAB31, member RAS oncogene family 20.0
RAB3B RAB3B, member RAS oncogene family 20.0
TMEM263 transmembrane protein 263 20.0
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 20.0
ZC3HAV1 zinc finger CCCH-type, antiviral 1 20.0
FKBP9 FK506 binding protein 9, 63 kDa 20.0
POGLUT1 protein O-glucosyltransferase 1 20.0
BCL10 B-cell CLL/lymphoma 10 20.0
ARF6 ADP-ribosylation factor 6 20.0
RTN4 reticulon 4 20.0
TMEM245 transmembrane protein 245 20.0
TMTC3 transmembrane and tetratricopeptide repeat containing 3 20.0
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 20.0
C6ORF62 chromosome 6 open reading frame 62 20.0
GOLGA3 golgin A3 20.0
SRSF6 serine/arginine-rich splicing factor 6 20.0
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 20.0
MRFAP1 Morf4 family associated protein 1 20.0
RHOBTB3 Rho-related BTB domain containing 3 20.0
PTRF polymerase I and transcript release factor 20.0
MAGT1 magnesium transporter 1 20.0
ZAK sterile alpha motif and leucine zipper containing kinase AZK 20.0
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 20.0
AEBP2 AE binding protein 2 20.0
GLG1 golgi glycoprotein 1 20.0
FAM101B family with sequence similarity 101, member B 20.0
SGPL1 sphingosine-1-phosphate lyase 1 20.0
NIPAL3 NIPA-like domain containing 3 20.0
CAMK2D calcium/calmodulin-dependent protein kinase II delta 20.0
PRSS8 protease, serine, 8 20.0
ADNP activity-dependent neuroprotector homeobox 20.0
BROX BRO1 domain and CAAX motif containing 20.0
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 20.0
TSPYL1 TSPY-like 1 20.0
PHACTR2 phosphatase and actin regulator 2 20.0
PTPN14 protein tyrosine phosphatase, non-receptor type 14 20.0
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 20.0
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 20.0
MAP1B microtubule-associated protein 1B 20.0
ADAM19 ADAM metallopeptidase domain 19 20.0
MEIS1 Meis homeobox 1 20.0
KCTD10 potassium channel tetramerization domain containing 10 20.0
CHP1 calcineurin-like EF-hand protein 1 20.0
TMEM33 transmembrane protein 33 20.0
CSNK1A1 casein kinase 1, alpha 1 20.0
AXL AXL receptor tyrosine kinase 20.0
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 20.0
PPP6R3 protein phosphatase 6, regulatory subunit 3 20.0
PXDN peroxidasin 20.0
WNT5A wingless-type MMTV integration site family, member 5A 20.0
DDAH1 dimethylarginine dimethylaminohydrolase 1 20.0
NLRP6 NLR family, pyrin domain containing 6 20.0
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe) 20.0
LOXL3 lysyl oxidase-like 3 20.0
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 20.0
CTTN cortactin 20.0
GPRC5A G protein-coupled receptor, class C, group 5, member A 20.0
FAM114A1 family with sequence similarity 114, member A1 20.0
SAR1A secretion associated, Ras related GTPase 1A 20.0
KPNA6 karyopherin alpha 6 (importin alpha 7) 20.0
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 20.0
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) 20.0
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 20.0
BAG4 BCL2-associated athanogene 4 20.0
USP22 ubiquitin specific peptidase 22 20.0
TIMP3 TIMP metallopeptidase inhibitor 3 20.0
FADS1 fatty acid desaturase 1 20.0
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 20.0
REEP3 receptor accessory protein 3 20.0
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 20.0

decreased expression

Symbol Name Standardized Value
BET1 Bet1 golgi vesicular membrane trafficking protein -20.0
LMAN2L lectin, mannose-binding 2-like -20.0
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -20.0
APOA1BP apolipoprotein A-I binding protein -20.0
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -20.0
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -20.0
RAB9A RAB9A, member RAS oncogene family -20.0
CSRP2 cysteine and glycine-rich protein 2 -20.0
STRA13 stimulated by retinoic acid 13 -20.0
AIP aryl hydrocarbon receptor interacting protein -20.0
CCDC115 coiled-coil domain containing 115 -20.0
CASP7 caspase 7, apoptosis-related cysteine peptidase -20.0
MRPL50 mitochondrial ribosomal protein L50 -20.0
MRPL55 mitochondrial ribosomal protein L55 -20.0
PNKD paroxysmal nonkinesigenic dyskinesia -20.0
RPUSD3 RNA pseudouridylate synthase domain containing 3 -20.0
PMF1 polyamine-modulated factor 1 -20.0
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa -20.0
AKIP1 A kinase (PRKA) interacting protein 1 -20.0
PEX19 peroxisomal biogenesis factor 19 -20.0
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 -20.0
GSKIP GSK3B interacting protein -20.0
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -20.0
MRPL54 mitochondrial ribosomal protein L54 -20.0
FAM136A family with sequence similarity 136, member A -20.0
PMPCB peptidase (mitochondrial processing) beta -20.0
CIAPIN1 cytokine induced apoptosis inhibitor 1 -20.0
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 -20.0
TMEM11 transmembrane protein 11 -20.0
LEPROTL1 leptin receptor overlapping transcript-like 1 -20.0
CCDC124 coiled-coil domain containing 124 -20.0
GSS glutathione synthetase -20.0
CD320 CD320 molecule -20.0
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -20.0
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -20.0
GOT1 glutamic-oxaloacetic transaminase 1, soluble -20.0
DOLK dolichol kinase -20.0
TSTA3 tissue specific transplantation antigen P35B -20.0
NSDHL NAD(P) dependent steroid dehydrogenase-like -20.0
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) -20.0
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -20.0
ISCA2 iron-sulfur cluster assembly 2 -20.0
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -20.0
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 -20.0
MAD2L1BP MAD2L1 binding protein -20.0
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 -20.0
ERI3 ERI1 exoribonuclease family member 3 -20.0
JAGN1 jagunal homolog 1 (Drosophila) -20.0
C16ORF62 chromosome 16 open reading frame 62 -20.0
YIPF2 Yip1 domain family, member 2 -20.0
BEX4 brain expressed, X-linked 4 -20.0
OCIAD2 OCIA domain containing 2 -20.0
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific -20.0
TMED1 transmembrane emp24 protein transport domain containing 1 -20.0
TMEM205 transmembrane protein 205 -20.0
PIH1D1 PIH1 domain containing 1 -20.0
UBL7 ubiquitin-like 7 -20.0
H2AFJ H2A histone family, member J -20.0
SFI1 Sfi1 homolog, spindle assembly associated (yeast) -20.0
ARL16 ADP-ribosylation factor-like 16 -20.0
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -20.0
GPN1 GPN-loop GTPase 1 -20.0
MRPL16 mitochondrial ribosomal protein L16 -20.0
THYN1 thymocyte nuclear protein 1 -20.0
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -20.0
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -20.0
ELP5 elongator acetyltransferase complex subunit 5 -20.0
C11ORF49 chromosome 11 open reading frame 49 -20.0
ALG3 ALG3, alpha-1,3- mannosyltransferase -20.0
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) -20.0
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 -20.0
FANCA Fanconi anemia, complementation group A -20.0
ARL2 ADP-ribosylation factor-like 2 -20.0
PDHX pyruvate dehydrogenase complex, component X -20.0
TRAPPC2L trafficking protein particle complex 2-like -20.0
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -20.0
SYNGR1 synaptogyrin 1 -20.0
UXT ubiquitously-expressed, prefoldin-like chaperone -20.0
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -20.0
TRUB2 TruB pseudouridine (psi) synthase family member 2 -20.0
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) -20.0
GPR108 G protein-coupled receptor 108 -20.0
RNF4 ring finger protein 4 -20.0
STX8 syntaxin 8 -20.0
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 -20.0
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -20.0
GMPR2 guanosine monophosphate reductase 2 -20.0
GMPPA GDP-mannose pyrophosphorylase A -20.0
NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 -20.0
LINC00998 long intergenic non-protein coding RNA 998 -20.0
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -20.0
NXF1 nuclear RNA export factor 1 -20.0
BANF1 barrier to autointegration factor 1 -20.0
COX14 COX14 cytochrome c oxidase assembly factor -20.0
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B -20.0
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -20.0
DPY30 dpy-30 homolog (C. elegans) -20.0
G6PC3 glucose 6 phosphatase, catalytic, 3 -20.0
C11ORF31 chromosome 11 open reading frame 31 -20.0
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -20.0