| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting FYTTD1 in fibroblasts BJ cell line (Study accession: SRP271175) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_6015_KD_FYTTD1_SRP271175 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 20.0 |
| TOB1 | transducer of ERBB2, 1 | 20.0 |
| SLC30A7 | solute carrier family 30 (zinc transporter), member 7 | 20.0 |
| EIF5B | eukaryotic translation initiation factor 5B | 20.0 |
| CDC42 | cell division cycle 42 | 20.0 |
| MARCH6 | membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase | 20.0 |
| COLGALT1 | collagen beta(1-O)galactosyltransferase 1 | 20.0 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 20.0 |
| NF2 | neurofibromin 2 (merlin) | 20.0 |
| BICC1 | BicC family RNA binding protein 1 | 20.0 |
| TTC39C | tetratricopeptide repeat domain 39C | 20.0 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 20.0 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 | 20.0 |
| TLK1 | tousled-like kinase 1 | 20.0 |
| CACUL1 | CDK2-associated, cullin domain 1 | 20.0 |
| NABP1 | nucleic acid binding protein 1 | 20.0 |
| SET | SET nuclear proto-oncogene | 20.0 |
| MYLK | myosin light chain kinase | 20.0 |
| GOLIM4 | golgi integral membrane protein 4 | 20.0 |
| DPYSL2 | dihydropyrimidinase-like 2 | 20.0 |
| NEMF | nuclear export mediator factor | 20.0 |
| NUDT19 | nudix (nucleoside diphosphate linked moiety X)-type motif 19 | 20.0 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 20.0 |
| ARRDC3 | arrestin domain containing 3 | 20.0 |
| RTN4 | reticulon 4 | 20.0 |
| TMTC3 | transmembrane and tetratricopeptide repeat containing 3 | 20.0 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 20.0 |
| SASH1 | SAM and SH3 domain containing 1 | 20.0 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 20.0 |
| TOR1AIP2 | torsin A interacting protein 2 | 20.0 |
| STRN3 | striatin, calmodulin binding protein 3 | 20.0 |
| RAB31 | RAB31, member RAS oncogene family | 20.0 |
| RAB3B | RAB3B, member RAS oncogene family | 20.0 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C | 20.0 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 20.0 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 20.0 |
| RPL17 | ribosomal protein L17 | 20.0 |
| PRKCA | protein kinase C, alpha | 20.0 |
| S1PR2 | sphingosine-1-phosphate receptor 2 | 20.0 |
| MTDH | metadherin | 20.0 |
| TNRC6B | trinucleotide repeat containing 6B | 20.0 |
| C6ORF62 | chromosome 6 open reading frame 62 | 20.0 |
| GOLGA3 | golgin A3 | 20.0 |
| SRSF6 | serine/arginine-rich splicing factor 6 | 20.0 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 20.0 |
| TXLNA | taxilin alpha | 20.0 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 20.0 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 20.0 |
| ARF6 | ADP-ribosylation factor 6 | 20.0 |
| PTRF | polymerase I and transcript release factor | 20.0 |
| PHACTR2 | phosphatase and actin regulator 2 | 20.0 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK | 20.0 |
| SFRP1 | secreted frizzled-related protein 1 | 20.0 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | 20.0 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 20.0 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 20.0 |
| GLG1 | golgi glycoprotein 1 | 20.0 |
| KIF3B | kinesin family member 3B | 20.0 |
| SGPL1 | sphingosine-1-phosphate lyase 1 | 20.0 |
| CBX6 | chromobox homolog 6 | 20.0 |
| ELMSAN1 | ELM2 and Myb/SANT-like domain containing 1 | 20.0 |
| BROX | BRO1 domain and CAAX motif containing | 20.0 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 20.0 |
| TSPYL1 | TSPY-like 1 | 20.0 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 20.0 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 20.0 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 20.0 |
| MAP1B | microtubule-associated protein 1B | 20.0 |
| ADAM19 | ADAM metallopeptidase domain 19 | 20.0 |
| MEIS1 | Meis homeobox 1 | 20.0 |
| KCTD10 | potassium channel tetramerization domain containing 10 | 20.0 |
| CHP1 | calcineurin-like EF-hand protein 1 | 20.0 |
| SKIL | SKI-like proto-oncogene | 20.0 |
| TMEM33 | transmembrane protein 33 | 20.0 |
| NIPAL3 | NIPA-like domain containing 3 | 20.0 |
| EPRS | glutamyl-prolyl-tRNA synthetase | 20.0 |
| NELL1 | NEL-like 1 (chicken) | 20.0 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 20.0 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 20.0 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 20.0 |
| PXDN | peroxidasin | 20.0 |
| NPEPPS | aminopeptidase puromycin sensitive | 20.0 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 20.0 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 20.0 |
| NLRP6 | NLR family, pyrin domain containing 6 | 20.0 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) | 20.0 |
| CCNI | cyclin I | 20.0 |
| REEP3 | receptor accessory protein 3 | 20.0 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | 20.0 |
| ADNP | activity-dependent neuroprotector homeobox | 20.0 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 20.0 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 20.0 |
| AXL | AXL receptor tyrosine kinase | 20.0 |
| KPNA6 | karyopherin alpha 6 (importin alpha 7) | 20.0 |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) | 20.0 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 20.0 |
| BAG4 | BCL2-associated athanogene 4 | 20.0 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 20.0 |
| FADS1 | fatty acid desaturase 1 | 20.0 |
| CTTN | cortactin | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMIM4 | small integral membrane protein 4 | -20.0 |
| TBRG4 | transforming growth factor beta regulator 4 | -20.0 |
| LINC00116 | long intergenic non-protein coding RNA 116 | -20.0 |
| GSTM4 | glutathione S-transferase mu 4 | -20.0 |
| TM4SF1 | transmembrane 4 L six family member 1 | -20.0 |
| CYB561D2 | cytochrome b561 family, member D2 | -20.0 |
| PRPF31 | pre-mRNA processing factor 31 | -20.0 |
| MED20 | mediator complex subunit 20 | -20.0 |
| YAE1D1 | Yae1 domain containing 1 | -20.0 |
| PDE6D | phosphodiesterase 6D, cGMP-specific, rod, delta | -20.0 |
| GOLGA7 | golgin A7 | -20.0 |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | -20.0 |
| PSENEN | presenilin enhancer gamma secretase subunit | -20.0 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) | -20.0 |
| TMEM216 | transmembrane protein 216 | -20.0 |
| TMEM218 | transmembrane protein 218 | -20.0 |
| CHCHD1 | coiled-coil-helix-coiled-coil-helix domain containing 1 | -20.0 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -20.0 |
| WDR54 | WD repeat domain 54 | -20.0 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 | -20.0 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 | -20.0 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) | -20.0 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -20.0 |
| FBXO8 | F-box protein 8 | -20.0 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N | -20.0 |
| ACOT2 | acyl-CoA thioesterase 2 | -20.0 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | -20.0 |
| BRMS1 | breast cancer metastasis suppressor 1 | -20.0 |
| RFXANK | regulatory factor X-associated ankyrin-containing protein | -20.0 |
| STON1 | stonin 1 | -20.0 |
| POP5 | processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) | -20.0 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -20.0 |
| AIMP2 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 | -20.0 |
| MFSD5 | major facilitator superfamily domain containing 5 | -20.0 |
| DGCR6L | DiGeorge syndrome critical region gene 6-like | -20.0 |
| STX18 | syntaxin 18 | -20.0 |
| GNPDA2 | glucosamine-6-phosphate deaminase 2 | -20.0 |
| RNF25 | ring finger protein 25 | -20.0 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 | -20.0 |
| RRAGB | Ras-related GTP binding B | -20.0 |
| WDR34 | WD repeat domain 34 | -20.0 |
| FAM206A | family with sequence similarity 206, member A | -20.0 |
| TFPT | TCF3 (E2A) fusion partner (in childhood Leukemia) | -20.0 |
| FIG4 | FIG4 phosphoinositide 5-phosphatase | -20.0 |
| SERTAD3 | SERTA domain containing 3 | -20.0 |
| BBS9 | Bardet-Biedl syndrome 9 | -20.0 |
| MRPL4 | mitochondrial ribosomal protein L4 | -20.0 |
| LACTB2 | lactamase, beta 2 | -20.0 |
| CDK5 | cyclin-dependent kinase 5 | -20.0 |
| FLAD1 | flavin adenine dinucleotide synthetase 1 | -20.0 |
| AAAS | achalasia, adrenocortical insufficiency, alacrimia | -20.0 |
| NIF3L1 | NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) | -20.0 |
| B9D1 | B9 protein domain 1 | -20.0 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | -20.0 |
| PRAF2 | PRA1 domain family, member 2 | -20.0 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa | -20.0 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 | -20.0 |
| AAMDC | adipogenesis associated, Mth938 domain containing | -20.0 |
| ZFAND2A | zinc finger, AN1-type domain 2A | -20.0 |
| TMEM101 | transmembrane protein 101 | -20.0 |
| PYCARD | PYD and CARD domain containing | -20.0 |
| TMEM134 | transmembrane protein 134 | -20.0 |
| GPKOW | G patch domain and KOW motifs | -20.0 |
| ALKBH7 | alkB, alkylation repair homolog 7 (E. coli) | -20.0 |
| ST7 | suppression of tumorigenicity 7 | -20.0 |
| HAGH | hydroxyacylglutathione hydrolase | -20.0 |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 | -20.0 |
| QPCT | glutaminyl-peptide cyclotransferase | -20.0 |
| DCXR | dicarbonyl/L-xylulose reductase | -20.0 |
| CHCHD5 | coiled-coil-helix-coiled-coil-helix domain containing 5 | -20.0 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | -20.0 |
| LYRM5 | LYR motif containing 5 | -20.0 |
| TAPBPL | TAP binding protein-like | -20.0 |
| MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | -20.0 |
| MRPL48 | mitochondrial ribosomal protein L48 | -20.0 |
| NDUFA13 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 | -20.0 |
| DHRS1 | dehydrogenase/reductase (SDR family) member 1 | -20.0 |
| TXNDC12 | thioredoxin domain containing 12 (endoplasmic reticulum) | -20.0 |
| C9ORF89 | chromosome 9 open reading frame 89 | -20.0 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa | -20.0 |
| ATG101 | autophagy related 101 | -20.0 |
| PMVK | phosphomevalonate kinase | -20.0 |
| HIST2H2BE | histone cluster 2, H2be | -20.0 |
| COQ9 | coenzyme Q9 | -20.0 |
| MGMT | O-6-methylguanine-DNA methyltransferase | -20.0 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase | -20.0 |
| ACAD9 | acyl-CoA dehydrogenase family, member 9 | -20.0 |
| ACAD8 | acyl-CoA dehydrogenase family, member 8 | -20.0 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | -20.0 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -20.0 |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B | -20.0 |
| EXOSC4 | exosome component 4 | -20.0 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -20.0 |
| BLVRB | biliverdin reductase B | -20.0 |
| CCDC28B | coiled-coil domain containing 28B | -20.0 |
| ANXA3 | annexin A3 | -20.0 |
| NMRK1 | nicotinamide riboside kinase 1 | -20.0 |
| CSTF2 | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa | -20.0 |
| LAS1L | LAS1-like (S. cerevisiae) | -20.0 |
| DCP1B | decapping mRNA 1B | -20.0 |
