Perturb_6029_KD_KHDRBS3_SRP271175 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting KHDRBS3 in fibroblasts BJ cell line (Study accession: SRP271175) (PerturbAtlas)
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Genes

200 genes differentially expressed following the Perturb_6029_KD_KHDRBS3_SRP271175 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
NABP1 nucleic acid binding protein 1 20.0
TOB1 transducer of ERBB2, 1 20.0
EIF5B eukaryotic translation initiation factor 5B 20.0
CDC42 cell division cycle 42 20.0
ZNF106 zinc finger protein 106 20.0
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 20.0
COLGALT1 collagen beta(1-O)galactosyltransferase 1 20.0
NF2 neurofibromin 2 (merlin) 20.0
BICC1 BicC family RNA binding protein 1 20.0
TTC39C tetratricopeptide repeat domain 39C 20.0
RTN4 reticulon 4 20.0
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 20.0
RBM6 RNA binding motif protein 6 20.0
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 20.0
SET SET nuclear proto-oncogene 20.0
SDC4 syndecan 4 20.0
GOLIM4 golgi integral membrane protein 4 20.0
NEMF nuclear export mediator factor 20.0
DIO2 deiodinase, iodothyronine, type II 20.0
UBE2B ubiquitin-conjugating enzyme E2B 20.0
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 20.0
TLK1 tousled-like kinase 1 20.0
TACC1 transforming, acidic coiled-coil containing protein 1 20.0
ANKRD10 ankyrin repeat domain 10 20.0
TMEM245 transmembrane protein 245 20.0
MTDH metadherin 20.0
WBP1L WW domain binding protein 1-like 20.0
TOR1AIP2 torsin A interacting protein 2 20.0
STRN3 striatin, calmodulin binding protein 3 20.0
RAB31 RAB31, member RAS oncogene family 20.0
RAB3B RAB3B, member RAS oncogene family 20.0
TMEM263 transmembrane protein 263 20.0
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 20.0
ZC3HAV1 zinc finger CCCH-type, antiviral 1 20.0
FKBP9 FK506 binding protein 9, 63 kDa 20.0
EIF4B eukaryotic translation initiation factor 4B 20.0
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 20.0
RPL17 ribosomal protein L17 20.0
PRKCA protein kinase C, alpha 20.0
TNRC6B trinucleotide repeat containing 6B 20.0
ENAH enabled homolog (Drosophila) 20.0
C6ORF62 chromosome 6 open reading frame 62 20.0
SOX4 SRY (sex determining region Y)-box 4 20.0
GOLGA3 golgin A3 20.0
SRSF6 serine/arginine-rich splicing factor 6 20.0
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 20.0
MIER1 mesoderm induction early response 1, transcriptional regulator 20.0
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 20.0
RHOBTB3 Rho-related BTB domain containing 3 20.0
STAT2 signal transducer and activator of transcription 2, 113kDa 20.0
PHACTR2 phosphatase and actin regulator 2 20.0
GLG1 golgi glycoprotein 1 20.0
KIF3B kinesin family member 3B 20.0
SGPL1 sphingosine-1-phosphate lyase 1 20.0
TRIM59 tripartite motif containing 59 20.0
TMED4 transmembrane emp24 protein transport domain containing 4 20.0
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1 20.0
NIPAL3 NIPA-like domain containing 3 20.0
SERINC5 serine incorporator 5 20.0
ADNP activity-dependent neuroprotector homeobox 20.0
MARCKS myristoylated alanine-rich protein kinase C substrate 20.0
ZAK sterile alpha motif and leucine zipper containing kinase AZK 20.0
BROX BRO1 domain and CAAX motif containing 20.0
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 20.0
PTPN14 protein tyrosine phosphatase, non-receptor type 14 20.0
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 20.0
MAP1B microtubule-associated protein 1B 20.0
ADAM19 ADAM metallopeptidase domain 19 20.0
MEIS1 Meis homeobox 1 20.0
SLC35F6 solute carrier family 35, member F6 20.0
KCTD10 potassium channel tetramerization domain containing 10 20.0
CHP1 calcineurin-like EF-hand protein 1 20.0
TMEM33 transmembrane protein 33 20.0
TSPYL1 TSPY-like 1 20.0
AXL AXL receptor tyrosine kinase 20.0
KPNA6 karyopherin alpha 6 (importin alpha 7) 20.0
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 20.0
FAM171B family with sequence similarity 171, member B 20.0
PPP6R3 protein phosphatase 6, regulatory subunit 3 20.0
PXDN peroxidasin 20.0
NPEPPS aminopeptidase puromycin sensitive 20.0
DDAH1 dimethylarginine dimethylaminohydrolase 1 20.0
NLRP6 NLR family, pyrin domain containing 6 20.0
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe) 20.0
CTTN cortactin 20.0
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 20.0
GPRC5A G protein-coupled receptor, class C, group 5, member A 20.0
FAM114A1 family with sequence similarity 114, member A1 20.0
CCNI cyclin I 20.0
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 20.0
FNIP1 folliculin interacting protein 1 20.0
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) 20.0
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 20.0
BAG4 BCL2-associated athanogene 4 20.0
USP22 ubiquitin specific peptidase 22 20.0
TIMP3 TIMP metallopeptidase inhibitor 3 20.0
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 20.0
NONO non-POU domain containing, octamer-binding 20.0
REEP3 receptor accessory protein 3 20.0
CACUL1 CDK2-associated, cullin domain 1 20.0

decreased expression

Symbol Name Standardized Value
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) -20.0
CASP7 caspase 7, apoptosis-related cysteine peptidase -20.0
LMAN2L lectin, mannose-binding 2-like -20.0
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -20.0
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase -20.0
UMPS uridine monophosphate synthetase -20.0
BPGM 2,3-bisphosphoglycerate mutase -20.0
SCCPDH saccharopine dehydrogenase (putative) -20.0
MED20 mediator complex subunit 20 -20.0
AGTRAP angiotensin II receptor-associated protein -20.0
CSRP2 cysteine and glycine-rich protein 2 -20.0
MRPL55 mitochondrial ribosomal protein L55 -20.0
MRPL54 mitochondrial ribosomal protein L54 -20.0
PQBP1 polyglutamine binding protein 1 -20.0
COQ9 coenzyme Q9 -20.0
ACTR8 ARP8 actin-related protein 8 homolog (yeast) -20.0
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 -20.0
ETFB electron-transfer-flavoprotein, beta polypeptide -20.0
WIBG within bgcn homolog (Drosophila) -20.0
RPUSD3 RNA pseudouridylate synthase domain containing 3 -20.0
PMF1 polyamine-modulated factor 1 -20.0
AKIP1 A kinase (PRKA) interacting protein 1 -20.0
SIRT2 sirtuin 2 -20.0
CFAP20 cilia and flagella associated protein 20 -20.0
STRA13 stimulated by retinoic acid 13 -20.0
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -20.0
MRPL36 mitochondrial ribosomal protein L36 -20.0
CD320 CD320 molecule -20.0
NGRN neugrin, neurite outgrowth associated -20.0
SLC35A4 solute carrier family 35, member A4 -20.0
VWA9 von Willebrand factor A domain containing 9 -20.0
DPCD deleted in primary ciliary dyskinesia homolog (mouse) -20.0
COMMD4 COMM domain containing 4 -20.0
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -20.0
SF3B4 splicing factor 3b, subunit 4, 49kDa -20.0
YIPF1 Yip1 domain family, member 1 -20.0
CTNNBL1 catenin, beta like 1 -20.0
RNF25 ring finger protein 25 -20.0
C12ORF57 chromosome 12 open reading frame 57 -20.0
NHP2 NHP2 ribonucleoprotein -20.0
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -20.0
ISCA2 iron-sulfur cluster assembly 2 -20.0
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -20.0
LCMT1 leucine carboxyl methyltransferase 1 -20.0
CCDC12 coiled-coil domain containing 12 -20.0
MAD2L1BP MAD2L1 binding protein -20.0
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 -20.0
ERI3 ERI1 exoribonuclease family member 3 -20.0
NSDHL NAD(P) dependent steroid dehydrogenase-like -20.0
YIPF2 Yip1 domain family, member 2 -20.0
NCBP2-AS2 NCBP2 antisense RNA 2 (head to head) -20.0
MRPS12 mitochondrial ribosomal protein S12 -20.0
MRPS11 mitochondrial ribosomal protein S11 -20.0
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit -20.0
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -20.0
PRAF2 PRA1 domain family, member 2 -20.0
TMED1 transmembrane emp24 protein transport domain containing 1 -20.0
ACO2 aconitase 2, mitochondrial -20.0
TMEM69 transmembrane protein 69 -20.0
RABIF RAB interacting factor -20.0
ABT1 activator of basal transcription 1 -20.0
ERCC3 excision repair cross-complementation group 3 -20.0
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific -20.0
ZNF330 zinc finger protein 330 -20.0
ST7 suppression of tumorigenicity 7 -20.0
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 -20.0
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -20.0
ELP5 elongator acetyltransferase complex subunit 5 -20.0
C11ORF49 chromosome 11 open reading frame 49 -20.0
CCBL2 cysteine conjugate-beta lyase 2 -20.0
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase -20.0
MRPS9 mitochondrial ribosomal protein S9 -20.0
FANCA Fanconi anemia, complementation group A -20.0
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -20.0
TFB2M transcription factor B2, mitochondrial -20.0
ZNF706 zinc finger protein 706 -20.0
ACAD9 acyl-CoA dehydrogenase family, member 9 -20.0
G6PC3 glucose 6 phosphatase, catalytic, 3 -20.0
C11ORF31 chromosome 11 open reading frame 31 -20.0
STYXL1 serine/threonine/tyrosine interacting-like 1 -20.0
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) -20.0
FTSJ3 FtsJ homolog 3 (E. coli) -20.0
PBDC1 polysaccharide biosynthesis domain containing 1 -20.0
TUBG1 tubulin, gamma 1 -20.0
UXT ubiquitously-expressed, prefoldin-like chaperone -20.0
PMVK phosphomevalonate kinase -20.0
SELENBP1 selenium binding protein 1 -20.0
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B -20.0
COX14 COX14 cytochrome c oxidase assembly factor -20.0
TMEM101 transmembrane protein 101 -20.0
ALAS1 5'-aminolevulinate synthase 1 -20.0
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -20.0
ARL16 ADP-ribosylation factor-like 16 -20.0
NGDN neuroguidin, EIF4E binding protein -20.0
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like -20.0
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) -20.0
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -20.0
LINC00998 long intergenic non-protein coding RNA 998 -20.0
NXF1 nuclear RNA export factor 1 -20.0
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -20.0