| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting PHB in fibroblasts BJ cell line (Study accession: SRP271175) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_6047_KD_PHB_SRP271175 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SET | SET nuclear proto-oncogene | 20.0 |
| RBM6 | RNA binding motif protein 6 | 20.0 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 20.0 |
| TOB1 | transducer of ERBB2, 1 | 20.0 |
| EIF5B | eukaryotic translation initiation factor 5B | 20.0 |
| CDC42 | cell division cycle 42 | 20.0 |
| MARCH6 | membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase | 20.0 |
| COLGALT1 | collagen beta(1-O)galactosyltransferase 1 | 20.0 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 20.0 |
| NF2 | neurofibromin 2 (merlin) | 20.0 |
| BICC1 | BicC family RNA binding protein 1 | 20.0 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 20.0 |
| ANKRD10 | ankyrin repeat domain 10 | 20.0 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 | 20.0 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 20.0 |
| GOLIM4 | golgi integral membrane protein 4 | 20.0 |
| DPYSL2 | dihydropyrimidinase-like 2 | 20.0 |
| NEMF | nuclear export mediator factor | 20.0 |
| DIO2 | deiodinase, iodothyronine, type II | 20.0 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 20.0 |
| NUDT19 | nudix (nucleoside diphosphate linked moiety X)-type motif 19 | 20.0 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 20.0 |
| ARRDC3 | arrestin domain containing 3 | 20.0 |
| TLK1 | tousled-like kinase 1 | 20.0 |
| TTC39C | tetratricopeptide repeat domain 39C | 20.0 |
| TMEM245 | transmembrane protein 245 | 20.0 |
| TMEM41B | transmembrane protein 41B | 20.0 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 20.0 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 20.0 |
| CNTN1 | contactin 1 | 20.0 |
| TOR1AIP2 | torsin A interacting protein 2 | 20.0 |
| STRN3 | striatin, calmodulin binding protein 3 | 20.0 |
| RAB31 | RAB31, member RAS oncogene family | 20.0 |
| RAB3B | RAB3B, member RAS oncogene family | 20.0 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 20.0 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 20.0 |
| PRKCA | protein kinase C, alpha | 20.0 |
| ARHGAP1 | Rho GTPase activating protein 1 | 20.0 |
| ARF6 | ADP-ribosylation factor 6 | 20.0 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 20.0 |
| TMTC3 | transmembrane and tetratricopeptide repeat containing 3 | 20.0 |
| MTDH | metadherin | 20.0 |
| TNRC6B | trinucleotide repeat containing 6B | 20.0 |
| C6ORF62 | chromosome 6 open reading frame 62 | 20.0 |
| GOLGA3 | golgin A3 | 20.0 |
| SRSF6 | serine/arginine-rich splicing factor 6 | 20.0 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 20.0 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 20.0 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 20.0 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | 20.0 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 20.0 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 20.0 |
| GLG1 | golgi glycoprotein 1 | 20.0 |
| KIF3B | kinesin family member 3B | 20.0 |
| SGPL1 | sphingosine-1-phosphate lyase 1 | 20.0 |
| ELMSAN1 | ELM2 and Myb/SANT-like domain containing 1 | 20.0 |
| SERINC5 | serine incorporator 5 | 20.0 |
| EPRS | glutamyl-prolyl-tRNA synthetase | 20.0 |
| ADNP | activity-dependent neuroprotector homeobox | 20.0 |
| SCAF11 | SR-related CTD-associated factor 11 | 20.0 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 20.0 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 20.0 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK | 20.0 |
| BROX | BRO1 domain and CAAX motif containing | 20.0 |
| PSMB4 | proteasome (prosome, macropain) subunit, beta type, 4 | 20.0 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 20.0 |
| MAP1B | microtubule-associated protein 1B | 20.0 |
| ADAM19 | ADAM metallopeptidase domain 19 | 20.0 |
| MEIS1 | Meis homeobox 1 | 20.0 |
| KCTD10 | potassium channel tetramerization domain containing 10 | 20.0 |
| CHP1 | calcineurin-like EF-hand protein 1 | 20.0 |
| SKIL | SKI-like proto-oncogene | 20.0 |
| TSPYL1 | TSPY-like 1 | 20.0 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 20.0 |
| AXL | AXL receptor tyrosine kinase | 20.0 |
| KPNA6 | karyopherin alpha 6 (importin alpha 7) | 20.0 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 20.0 |
| PXDN | peroxidasin | 20.0 |
| NPEPPS | aminopeptidase puromycin sensitive | 20.0 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 20.0 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 20.0 |
| NLRP6 | NLR family, pyrin domain containing 6 | 20.0 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) | 20.0 |
| CTTN | cortactin | 20.0 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 20.0 |
| CACUL1 | CDK2-associated, cullin domain 1 | 20.0 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 20.0 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 20.0 |
| FAM114A1 | family with sequence similarity 114, member A1 | 20.0 |
| FNIP1 | folliculin interacting protein 1 | 20.0 |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) | 20.0 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 20.0 |
| TULP4 | tubby like protein 4 | 20.0 |
| USP22 | ubiquitin specific peptidase 22 | 20.0 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 20.0 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | 20.0 |
| HS3ST3B1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 | 20.0 |
| REEP3 | receptor accessory protein 3 | 20.0 |
| CCNI | cyclin I | 20.0 |
| NABP1 | nucleic acid binding protein 1 | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCGF1 | polycomb group ring finger 1 | -20.0 |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | -20.0 |
| PEX16 | peroxisomal biogenesis factor 16 | -20.0 |
| TBRG4 | transforming growth factor beta regulator 4 | -20.0 |
| LINC00116 | long intergenic non-protein coding RNA 116 | -20.0 |
| GSTM4 | glutathione S-transferase mu 4 | -20.0 |
| TM4SF1 | transmembrane 4 L six family member 1 | -20.0 |
| CYB561D2 | cytochrome b561 family, member D2 | -20.0 |
| MCEE | methylmalonyl CoA epimerase | -20.0 |
| MED20 | mediator complex subunit 20 | -20.0 |
| SDHAF2 | succinate dehydrogenase complex assembly factor 2 | -20.0 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 | -20.0 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 | -20.0 |
| OLFM4 | olfactomedin 4 | -20.0 |
| DCP1B | decapping mRNA 1B | -20.0 |
| SMIM4 | small integral membrane protein 4 | -20.0 |
| TMEM218 | transmembrane protein 218 | -20.0 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -20.0 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 | -20.0 |
| WDR54 | WD repeat domain 54 | -20.0 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 | -20.0 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) | -20.0 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -20.0 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) | -20.0 |
| CDA | cytidine deaminase | -20.0 |
| GOLGA7 | golgin A7 | -20.0 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | -20.0 |
| C14ORF142 | chromosome 14 open reading frame 142 | -20.0 |
| POP5 | processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) | -20.0 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -20.0 |
| AIMP2 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 | -20.0 |
| MFSD5 | major facilitator superfamily domain containing 5 | -20.0 |
| NTHL1 | nth endonuclease III-like 1 (E. coli) | -20.0 |
| RPL23 | ribosomal protein L23 | -20.0 |
| SNRNP35 | small nuclear ribonucleoprotein 35kDa (U11/U12) | -20.0 |
| COMMD5 | COMM domain containing 5 | -20.0 |
| GNPDA2 | glucosamine-6-phosphate deaminase 2 | -20.0 |
| RNF25 | ring finger protein 25 | -20.0 |
| RNF113A | ring finger protein 113A | -20.0 |
| CXORF40B | chromosome X open reading frame 40B | -20.0 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N | -20.0 |
| ACOT8 | acyl-CoA thioesterase 8 | -20.0 |
| ACOT2 | acyl-CoA thioesterase 2 | -20.0 |
| TFPT | TCF3 (E2A) fusion partner (in childhood Leukemia) | -20.0 |
| BBS9 | Bardet-Biedl syndrome 9 | -20.0 |
| MRPL2 | mitochondrial ribosomal protein L2 | -20.0 |
| TMEM234 | transmembrane protein 234 | -20.0 |
| CDK5 | cyclin-dependent kinase 5 | -20.0 |
| ZNF576 | zinc finger protein 576 | -20.0 |
| C16ORF91 | chromosome 16 open reading frame 91 | -20.0 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 | -20.0 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | -20.0 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa | -20.0 |
| SCRN2 | secernin 2 | -20.0 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 | -20.0 |
| AAMDC | adipogenesis associated, Mth938 domain containing | -20.0 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) | -20.0 |
| TMEM101 | transmembrane protein 101 | -20.0 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -20.0 |
| PYCARD | PYD and CARD domain containing | -20.0 |
| NGF | nerve growth factor (beta polypeptide) | -20.0 |
| RPS27 | ribosomal protein S27 | -20.0 |
| GPKOW | G patch domain and KOW motifs | -20.0 |
| ALKBH7 | alkB, alkylation repair homolog 7 (E. coli) | -20.0 |
| ST7 | suppression of tumorigenicity 7 | -20.0 |
| QPCT | glutaminyl-peptide cyclotransferase | -20.0 |
| POMT1 | protein-O-mannosyltransferase 1 | -20.0 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -20.0 |
| DCXR | dicarbonyl/L-xylulose reductase | -20.0 |
| HIST1H1C | histone cluster 1, H1c | -20.0 |
| CHCHD6 | coiled-coil-helix-coiled-coil-helix domain containing 6 | -20.0 |
| CHCHD5 | coiled-coil-helix-coiled-coil-helix domain containing 5 | -20.0 |
| LYRM5 | LYR motif containing 5 | -20.0 |
| TAPBPL | TAP binding protein-like | -20.0 |
| KRT17 | keratin 17, type I | -20.0 |
| NDUFA13 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 | -20.0 |
| SUGP1 | SURP and G patch domain containing 1 | -20.0 |
| TXNDC12 | thioredoxin domain containing 12 (endoplasmic reticulum) | -20.0 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa | -20.0 |
| PRPS1 | phosphoribosyl pyrophosphate synthetase 1 | -20.0 |
| PMVK | phosphomevalonate kinase | -20.0 |
| HIST2H2BE | histone cluster 2, H2be | -20.0 |
| COQ9 | coenzyme Q9 | -20.0 |
| MGMT | O-6-methylguanine-DNA methyltransferase | -20.0 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase | -20.0 |
| FAM118B | family with sequence similarity 118, member B | -20.0 |
| DHRS4 | dehydrogenase/reductase (SDR family) member 4 | -20.0 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | -20.0 |
| NUDT22 | nudix (nucleoside diphosphate linked moiety X)-type motif 22 | -20.0 |
| MGST2 | microsomal glutathione S-transferase 2 | -20.0 |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B | -20.0 |
| PDGFRL | platelet-derived growth factor receptor-like | -20.0 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -20.0 |
| CCDC28B | coiled-coil domain containing 28B | -20.0 |
| CD82 | CD82 molecule | -20.0 |
| ANXA3 | annexin A3 | -20.0 |
| SAYSD1 | SAYSVFN motif domain containing 1 | -20.0 |
| CSTF2 | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa | -20.0 |
| RAB7B | RAB7B, member RAS oncogene family | -20.0 |
| TUSC2 | tumor suppressor candidate 2 | -20.0 |
