| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting SLTM in fibroblasts BJ cell line (Study accession: SRP271175) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_6071_KD_SLTM_SRP271175 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOXL3 | lysyl oxidase-like 3 | 20.0 |
| TLK1 | tousled-like kinase 1 | 20.0 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 | 20.0 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 20.0 |
| TOB1 | transducer of ERBB2, 1 | 20.0 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 | 20.0 |
| EIF5B | eukaryotic translation initiation factor 5B | 20.0 |
| CDC42 | cell division cycle 42 | 20.0 |
| ZNF106 | zinc finger protein 106 | 20.0 |
| MARCH6 | membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase | 20.0 |
| COLGALT1 | collagen beta(1-O)galactosyltransferase 1 | 20.0 |
| ARRDC3 | arrestin domain containing 3 | 20.0 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 20.0 |
| NUDT19 | nudix (nucleoside diphosphate linked moiety X)-type motif 19 | 20.0 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 | 20.0 |
| CTTN | cortactin | 20.0 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 20.0 |
| CACUL1 | CDK2-associated, cullin domain 1 | 20.0 |
| NABP1 | nucleic acid binding protein 1 | 20.0 |
| SET | SET nuclear proto-oncogene | 20.0 |
| DPYSL2 | dihydropyrimidinase-like 2 | 20.0 |
| NEMF | nuclear export mediator factor | 20.0 |
| DIO2 | deiodinase, iodothyronine, type II | 20.0 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 20.0 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 20.0 |
| NF2 | neurofibromin 2 (merlin) | 20.0 |
| C2ORF68 | chromosome 2 open reading frame 68 | 20.0 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 20.0 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 20.0 |
| RPL7L1 | ribosomal protein L7-like 1 | 20.0 |
| TOR1AIP2 | torsin A interacting protein 2 | 20.0 |
| STRN3 | striatin, calmodulin binding protein 3 | 20.0 |
| RAB31 | RAB31, member RAS oncogene family | 20.0 |
| RAB3B | RAB3B, member RAS oncogene family | 20.0 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C | 20.0 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 20.0 |
| PRKCA | protein kinase C, alpha | 20.0 |
| S1PR2 | sphingosine-1-phosphate receptor 2 | 20.0 |
| ARF6 | ADP-ribosylation factor 6 | 20.0 |
| BICC1 | BicC family RNA binding protein 1 | 20.0 |
| TTC39C | tetratricopeptide repeat domain 39C | 20.0 |
| TMEM245 | transmembrane protein 245 | 20.0 |
| TMTC3 | transmembrane and tetratricopeptide repeat containing 3 | 20.0 |
| MTDH | metadherin | 20.0 |
| C6ORF62 | chromosome 6 open reading frame 62 | 20.0 |
| GOLGA3 | golgin A3 | 20.0 |
| SRSF6 | serine/arginine-rich splicing factor 6 | 20.0 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 20.0 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 20.0 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 20.0 |
| MAGT1 | magnesium transporter 1 | 20.0 |
| BROX | BRO1 domain and CAAX motif containing | 20.0 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK | 20.0 |
| EGR1 | early growth response 1 | 20.0 |
| SFRP1 | secreted frizzled-related protein 1 | 20.0 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | 20.0 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 20.0 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 20.0 |
| GLG1 | golgi glycoprotein 1 | 20.0 |
| KIF3B | kinesin family member 3B | 20.0 |
| SGPL1 | sphingosine-1-phosphate lyase 1 | 20.0 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 20.0 |
| TSPYL1 | TSPY-like 1 | 20.0 |
| TMEM33 | transmembrane protein 33 | 20.0 |
| PHACTR2 | phosphatase and actin regulator 2 | 20.0 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 20.0 |
| PSMB4 | proteasome (prosome, macropain) subunit, beta type, 4 | 20.0 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 20.0 |
| ADAM19 | ADAM metallopeptidase domain 19 | 20.0 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | 20.0 |
| MEIS1 | Meis homeobox 1 | 20.0 |
| KCTD10 | potassium channel tetramerization domain containing 10 | 20.0 |
| CHP1 | calcineurin-like EF-hand protein 1 | 20.0 |
| SKIL | SKI-like proto-oncogene | 20.0 |
| TRIM59 | tripartite motif containing 59 | 20.0 |
| ELMSAN1 | ELM2 and Myb/SANT-like domain containing 1 | 20.0 |
| CCNI | cyclin I | 20.0 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 20.0 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 20.0 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 20.0 |
| PXDN | peroxidasin | 20.0 |
| NPEPPS | aminopeptidase puromycin sensitive | 20.0 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 20.0 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 20.0 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 20.0 |
| NLRP6 | NLR family, pyrin domain containing 6 | 20.0 |
| REEP3 | receptor accessory protein 3 | 20.0 |
| HS3ST3B1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 | 20.0 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | 20.0 |
| ADNP | activity-dependent neuroprotector homeobox | 20.0 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 20.0 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 20.0 |
| AXL | AXL receptor tyrosine kinase | 20.0 |
| KPNA6 | karyopherin alpha 6 (importin alpha 7) | 20.0 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 20.0 |
| BAG4 | BCL2-associated athanogene 4 | 20.0 |
| USP22 | ubiquitin specific peptidase 22 | 20.0 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 20.0 |
| FADS1 | fatty acid desaturase 1 | 20.0 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCP1B | decapping mRNA 1B | -20.0 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -20.0 |
| ATG9A | autophagy related 9A | -20.0 |
| MCEE | methylmalonyl CoA epimerase | -20.0 |
| GCDH | glutaryl-CoA dehydrogenase | -20.0 |
| MED27 | mediator complex subunit 27 | -20.0 |
| UPRT | uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) | -20.0 |
| SDHAF2 | succinate dehydrogenase complex assembly factor 2 | -20.0 |
| CXORF40B | chromosome X open reading frame 40B | -20.0 |
| ZMAT5 | zinc finger, matrin-type 5 | -20.0 |
| CETN3 | centrin, EF-hand protein, 3 | -20.0 |
| BCS1L | BC1 (ubiquinol-cytochrome c reductase) synthesis-like | -20.0 |
| GSTM4 | glutathione S-transferase mu 4 | -20.0 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 | -20.0 |
| ERMARD | ER membrane-associated RNA degradation | -20.0 |
| TMEM216 | transmembrane protein 216 | -20.0 |
| TMEM218 | transmembrane protein 218 | -20.0 |
| COX17 | COX17 cytochrome c oxidase copper chaperone | -20.0 |
| C9ORF156 | chromosome 9 open reading frame 156 | -20.0 |
| HIST1H2BG | histone cluster 1, H2bg | -20.0 |
| MTERF4 | mitochondrial transcription termination factor 4 | -20.0 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) | -20.0 |
| PSENEN | presenilin enhancer gamma secretase subunit | -20.0 |
| OLFM4 | olfactomedin 4 | -20.0 |
| ACOT8 | acyl-CoA thioesterase 8 | -20.0 |
| ACOT2 | acyl-CoA thioesterase 2 | -20.0 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | -20.0 |
| PNPLA4 | patatin-like phospholipase domain containing 4 | -20.0 |
| RFXANK | regulatory factor X-associated ankyrin-containing protein | -20.0 |
| RNF185 | ring finger protein 185 | -20.0 |
| FASTKD5 | FAST kinase domains 5 | -20.0 |
| RAB38 | RAB38, member RAS oncogene family | -20.0 |
| NTHL1 | nth endonuclease III-like 1 (E. coli) | -20.0 |
| LYPLAL1 | lysophospholipase-like 1 | -20.0 |
| RPL23 | ribosomal protein L23 | -20.0 |
| COMMD3 | COMM domain containing 3 | -20.0 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | -20.0 |
| RNF113A | ring finger protein 113A | -20.0 |
| CDK5 | cyclin-dependent kinase 5 | -20.0 |
| TSSC1 | tumor suppressing subtransferable candidate 1 | -20.0 |
| RRAGB | Ras-related GTP binding B | -20.0 |
| FAM206A | family with sequence similarity 206, member A | -20.0 |
| TFPT | TCF3 (E2A) fusion partner (in childhood Leukemia) | -20.0 |
| ISOC1 | isochorismatase domain containing 1 | -20.0 |
| BBS9 | Bardet-Biedl syndrome 9 | -20.0 |
| MRPL2 | mitochondrial ribosomal protein L2 | -20.0 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -20.0 |
| TMEM234 | transmembrane protein 234 | -20.0 |
| LACTB2 | lactamase, beta 2 | -20.0 |
| C16ORF91 | chromosome 16 open reading frame 91 | -20.0 |
| TRAPPC6A | trafficking protein particle complex 6A | -20.0 |
| GPKOW | G patch domain and KOW motifs | -20.0 |
| RPS27 | ribosomal protein S27 | -20.0 |
| RPP25L | ribonuclease P/MRP 25kDa subunit-like | -20.0 |
| DNAJC11 | DnaJ (Hsp40) homolog, subfamily C, member 11 | -20.0 |
| AAMDC | adipogenesis associated, Mth938 domain containing | -20.0 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) | -20.0 |
| PDCL3 | phosducin-like 3 | -20.0 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -20.0 |
| CCDC51 | coiled-coil domain containing 51 | -20.0 |
| NGF | nerve growth factor (beta polypeptide) | -20.0 |
| ALKBH2 | alkB, alkylation repair homolog 2 (E. coli) | -20.0 |
| TAPBPL | TAP binding protein-like | -20.0 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | -20.0 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 | -20.0 |
| SPRYD4 | SPRY domain containing 4 | -20.0 |
| N6AMT2 | N-6 adenine-specific DNA methyltransferase 2 (putative) | -20.0 |
| GSTZ1 | glutathione S-transferase zeta 1 | -20.0 |
| CHMP6 | charged multivesicular body protein 6 | -20.0 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -20.0 |
| HIST1H1C | histone cluster 1, H1c | -20.0 |
| UBXN11 | UBX domain protein 11 | -20.0 |
| MTX1 | metaxin 1 | -20.0 |
| CHCHD6 | coiled-coil-helix-coiled-coil-helix domain containing 6 | -20.0 |
| KRT17 | keratin 17, type I | -20.0 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -20.0 |
| ACAD8 | acyl-CoA dehydrogenase family, member 8 | -20.0 |
| DHRS4 | dehydrogenase/reductase (SDR family) member 4 | -20.0 |
| FARS2 | phenylalanyl-tRNA synthetase 2, mitochondrial | -20.0 |
| WRAP53 | WD repeat containing, antisense to TP53 | -20.0 |
| CIART | circadian associated repressor of transcription | -20.0 |
| HIST2H2BE | histone cluster 2, H2be | -20.0 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase | -20.0 |
| S100A3 | S100 calcium binding protein A3 | -20.0 |
| TUSC2 | tumor suppressor candidate 2 | -20.0 |
| TMEM140 | transmembrane protein 140 | -20.0 |
| HACL1 | 2-hydroxyacyl-CoA lyase 1 | -20.0 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | -20.0 |
| CSTF2 | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa | -20.0 |
| MGST2 | microsomal glutathione S-transferase 2 | -20.0 |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B | -20.0 |
| PARL | presenilin associated, rhomboid-like | -20.0 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -20.0 |
| APOL2 | apolipoprotein L, 2 | -20.0 |
| BIN3 | bridging integrator 3 | -20.0 |
| CCDC167 | coiled-coil domain containing 167 | -20.0 |
| TEX30 | testis expressed 30 | -20.0 |
| TCN2 | transcobalamin II | -20.0 |
| SAYSD1 | SAYSVFN motif domain containing 1 | -20.0 |
| PCGF1 | polycomb group ring finger 1 | -20.0 |
