Perturb_6288_KO|OE_WWTR1|YAP1_SRP292920 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KO|OE perturbation targeting WWTR1|YAP1 in Gastric cancer cell MKN28 cell line (Study accession: SRP292920) (PerturbAtlas)
Similar Terms
Downloads & Tools

Genes

47 genes differentially expressed following the Perturb_6288_KO|OE_WWTR1|YAP1_SRP292920 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
P4HA3 prolyl 4-hydroxylase, alpha polypeptide III 11.5041
COL4A2 collagen, type IV, alpha 2 10.0858
YAP1 Yes-associated protein 1 8.16234
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 8.01714
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 4.9892
RSPH14 radial spoke head 14 homolog (Chlamydomonas) 4.0221
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit 3.91876
ABI2 abl-interactor 2 3.91308
ACBD6 acyl-CoA binding domain containing 6 3.37551
NUDCD1 NudC domain containing 1 2.47781
TRIM14 tripartite motif containing 14 2.43061
CLDN22 claudin 22 2.02952
TICRR TOPBP1-interacting checkpoint and replication regulator 2.02585
GPN3 GPN-loop GTPase 3 1.9496
TPM1 tropomyosin 1 (alpha) 1.74098
SPATA9 spermatogenesis associated 9 1.66191
TREH trehalase (brush-border membrane glycoprotein) 1.6548
EPHA1 EPH receptor A1 1.642
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 1.52344
TGM2 transglutaminase 2 1.50561
RAB40A RAB40A, member RAS oncogene family 1.4526
GJA5 gap junction protein, alpha 5, 40kDa 1.42203
FKBP15 FK506 binding protein 15, 133kDa 1.42149
FGFR1 fibroblast growth factor receptor 1 1.40036
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) 1.39863
RELL1 RELT-like 1 1.35022
PLCE1 phospholipase C, epsilon 1 1.34034
FSIP1 fibrous sheath interacting protein 1 1.33417
CBR4 carbonyl reductase 4 1.30554
PRKCE protein kinase C, epsilon 1.30554
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 1.30554
GBA2 glucosidase, beta (bile acid) 2 1.30357
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 1.30357

decreased expression

Symbol Name Standardized Value
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -4.90842
JRK Jrk homolog (mouse) -4.869
LIPM lipase, family member M -4.77761
UTS2 urotensin 2 -4.08284
STAG3 stromal antigen 3 -3.91876
MYBBP1A MYB binding protein (P160) 1a -2.52712
DIAPH2 diaphanous-related formin 2 -2.22975
FAM151A family with sequence similarity 151, member A -2.17552
KAZN kazrin, periplakin interacting protein -1.85599
SCART1 scavenger receptor protein family member -1.85271
MED12L mediator complex subunit 12-like -1.80437
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) -1.68523
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 -1.37651
WBSCR16 Williams-Beuren syndrome chromosome region 16 -1.34034