| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting SNHG5 in HCT116 cell line (Study accession: SRP068373) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_6799_KD_SNHG5_SRP068373 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 20.0 |
| SMIM15 | small integral membrane protein 15 | 20.0 |
| ATG12 | autophagy related 12 | 20.0 |
| GDF15 | growth differentiation factor 15 | 20.0 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | 20.0 |
| ARRDC3 | arrestin domain containing 3 | 20.0 |
| GNG5 | guanine nucleotide binding protein (G protein), gamma 5 | 20.0 |
| EID3 | EP300 interacting inhibitor of differentiation 3 | 20.0 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 20.0 |
| PARD6B | par-6 family cell polarity regulator beta | 20.0 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 20.0 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 20.0 |
| HOXA3 | homeobox A3 | 20.0 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | 20.0 |
| HOXA5 | homeobox A5 | 20.0 |
| FTL | ferritin, light polypeptide | 20.0 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | 19.699 |
| DESI1 | desumoylating isopeptidase 1 | 19.3979 |
| IFRD1 | interferon-related developmental regulator 1 | 19.301 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 | 18.3872 |
| CCNA2 | cyclin A2 | 18.2076 |
| ZNF367 | zinc finger protein 367 | 17.8356 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 17.5331 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 17.0458 |
| SKIDA1 | SKI/DACH domain containing 1 | 16.3664 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 16.3232 |
| MORF4L2 | mortality factor 4 like 2 | 16.277 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) | 16.0956 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 15.8351 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 15.6872 |
| NUAK2 | NUAK family, SNF1-like kinase, 2 | 15.4449 |
| HDGF | hepatoma-derived growth factor | 15.085 |
| VGF | VGF nerve growth factor inducible | 15.065 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 14.8588 |
| GRB2 | growth factor receptor-bound protein 2 | 14.8211 |
| BRSK1 | BR serine/threonine kinase 1 | 14.8111 |
| DBP | D site of albumin promoter (albumin D-box) binding protein | 14.4996 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 14.2702 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 14.2055 |
| ARL14EPL | ADP-ribosylation factor-like 14 effector protein-like | 14.0509 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 14.0421 |
| ZBTB34 | zinc finger and BTB domain containing 34 | 13.9951 |
| VMP1 | vacuole membrane protein 1 | 13.8939 |
| ZFP36 | ZFP36 ring finger protein | 13.8365 |
| LAMB3 | laminin, beta 3 | 13.7369 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 13.6921 |
| ZNF467 | zinc finger protein 467 | 13.6657 |
| MBD6 | methyl-CpG binding domain protein 6 | 13.5791 |
| OVGP1 | oviductal glycoprotein 1, 120kDa | 13.5281 |
| IER3 | immediate early response 3 | 13.5027 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | 13.4331 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 13.3544 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 13.3544 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | 13.2358 |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | 13.0325 |
| DSC2 | desmocollin 2 | 12.9008 |
| LVRN | laeverin | 12.7943 |
| MDK | midkine (neurite growth-promoting factor 2) | 12.7927 |
| SPOPL | speckle-type POZ protein-like | 12.7701 |
| UNC13D | unc-13 homolog D (C. elegans) | 12.5131 |
| CREBRF | CREB3 regulatory factor | 12.3719 |
| GRAMD1B | GRAM domain containing 1B | 12.3552 |
| SESN1 | sestrin 1 | 12.3271 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | 12.2254 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 | 12.1127 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 11.6582 |
| SSU72 | SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) | 11.6503 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 11.6495 |
| MTF2 | metal response element binding transcription factor 2 | 11.6493 |
| PPIL3 | peptidylprolyl isomerase (cyclophilin)-like 3 | 11.3332 |
| FERMT2 | fermitin family member 2 | 11.0513 |
| ADM | adrenomedullin | 11.0146 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 10.9546 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 10.6908 |
| BBC3 | BCL2 binding component 3 | 10.5273 |
| IFNE | interferon, epsilon | 10.5185 |
| FTH1 | ferritin, heavy polypeptide 1 | 10.4763 |
| SUMO2 | small ubiquitin-like modifier 2 | 10.4602 |
| MICB | MHC class I polypeptide-related sequence B | 10.3941 |
| RIOK3 | RIO kinase 3 | 10.2392 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 10.1995 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 10.1626 |
| RHOA | ras homolog family member A | 10.1446 |
| UBB | ubiquitin B | 10.1352 |
| WASF1 | WAS protein family, member 1 | 9.96453 |
| APOLD1 | apolipoprotein L domain containing 1 | 9.95611 |
| HOXA10 | homeobox A10 | 9.88922 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 9.86088 |
| RGS17 | regulator of G-protein signaling 17 | 9.84816 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 9.80967 |
| HMOX1 | heme oxygenase 1 | 9.78725 |
| ZFHX3 | zinc finger homeobox 3 | 9.73467 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 9.73436 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 | 9.66961 |
| MBTD1 | mbt domain containing 1 | 9.64778 |
| PHF21A | PHD finger protein 21A | 9.64365 |
| AREG | amphiregulin | 9.57564 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 9.57458 |
| NHLRC3 | NHL repeat containing 3 | 9.53151 |
| RPS27 | ribosomal protein S27 | 9.51785 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -20.0 |
| ARPIN | actin-related protein 2/3 complex inhibitor | -20.0 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | -20.0 |
| BCL7A | B-cell CLL/lymphoma 7A | -20.0 |
| SART1 | squamous cell carcinoma antigen recognized by T cells | -20.0 |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 | -20.0 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B | -20.0 |
| LRRC8A | leucine rich repeat containing 8 family, member A | -20.0 |
| RBM17 | RNA binding motif protein 17 | -20.0 |
| SOX4 | SRY (sex determining region Y)-box 4 | -20.0 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | -20.0 |
| FSCN1 | fascin actin-bundling protein 1 | -20.0 |
| CANT1 | calcium activated nucleotidase 1 | -20.0 |
| NELFA | negative elongation factor complex member A | -20.0 |
| ITPA | inosine triphosphatase (nucleoside triphosphate pyrophosphatase) | -20.0 |
| FLOT2 | flotillin 2 | -20.0 |
| CNN2 | calponin 2 | -20.0 |
| MYL9 | myosin, light chain 9, regulatory | -20.0 |
| WWC1 | WW and C2 domain containing 1 | -20.0 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 | -20.0 |
| EHBP1L1 | EH domain binding protein 1-like 1 | -20.0 |
| TNS4 | tensin 4 | -20.0 |
| BAD | BCL2-associated agonist of cell death | -20.0 |
| SCARA3 | scavenger receptor class A, member 3 | -20.0 |
| ARHGAP18 | Rho GTPase activating protein 18 | -20.0 |
| ARFIP1 | ADP-ribosylation factor interacting protein 1 | -20.0 |
| LAMTOR1 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 | -20.0 |
| COL13A1 | collagen, type XIII, alpha 1 | -20.0 |
| FAM127B | family with sequence similarity 127, member B | -20.0 |
| FAM127A | family with sequence similarity 127, member A | -20.0 |
| ABHD14B | abhydrolase domain containing 14B | -20.0 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -20.0 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -20.0 |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | -20.0 |
| ADI1 | acireductone dioxygenase 1 | -20.0 |
| RSL24D1 | ribosomal L24 domain containing 1 | -20.0 |
| KLK1 | kallikrein 1 | -20.0 |
| FGFRL1 | fibroblast growth factor receptor-like 1 | -20.0 |
| RAB11FIP4 | RAB11 family interacting protein 4 (class II) | -20.0 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | -20.0 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -20.0 |
| ITFG3 | integrin alpha FG-GAP repeat containing 3 | -20.0 |
| RABEPK | Rab9 effector protein with kelch motifs | -20.0 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -20.0 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | -20.0 |
| GIPC1 | GIPC PDZ domain containing family, member 1 | -20.0 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 | -20.0 |
| XAB2 | XPA binding protein 2 | -20.0 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | -20.0 |
| GLRX5 | glutaredoxin 5 | -20.0 |
| FLNA | filamin A, alpha | -20.0 |
| ZNF704 | zinc finger protein 704 | -20.0 |
| AP2A1 | adaptor-related protein complex 2, alpha 1 subunit | -20.0 |
| CCM2 | cerebral cavernous malformation 2 | -20.0 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 | -20.0 |
| RPA1 | replication protein A1, 70kDa | -20.0 |
| WDR1 | WD repeat domain 1 | -20.0 |
| FAM101B | family with sequence similarity 101, member B | -20.0 |
| OGFR | opioid growth factor receptor | -20.0 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | -20.0 |
| CDC34 | cell division cycle 34 | -20.0 |
| ACTN4 | actinin, alpha 4 | -20.0 |
| CHPF | chondroitin polymerizing factor | -20.0 |
| BTG3 | BTG family, member 3 | -20.0 |
| SYNGR2 | synaptogyrin 2 | -20.0 |
| UBAC1 | UBA domain containing 1 | -20.0 |
| LRP3 | low density lipoprotein receptor-related protein 3 | -20.0 |
| CCSAP | centriole, cilia and spindle-associated protein | -20.0 |
| LMNB2 | lamin B2 | -20.0 |
| PALM | paralemmin | -20.0 |
| CERCAM | cerebral endothelial cell adhesion molecule | -20.0 |
| BCAS4 | breast carcinoma amplified sequence 4 | -20.0 |
| ZBED2 | zinc finger, BED-type containing 2 | -20.0 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -20.0 |
| LIMK1 | LIM domain kinase 1 | -20.0 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 | -20.0 |
| AGPAT1 | 1-acylglycerol-3-phosphate O-acyltransferase 1 | -20.0 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | -20.0 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -20.0 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -20.0 |
| TBCD | tubulin folding cofactor D | -20.0 |
| R3HCC1 | R3H domain and coiled-coil containing 1 | -20.0 |
| FAM83F | family with sequence similarity 83, member F | -20.0 |
| RABL6 | RAB, member RAS oncogene family-like 6 | -20.0 |
| GNPAT | glyceronephosphate O-acyltransferase | -20.0 |
| TTYH3 | tweety family member 3 | -19.699 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -19.699 |
| SNX7 | sorting nexin 7 | -19.3979 |
| SH2D5 | SH2 domain containing 5 | -19.1549 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -18.8539 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | -18.5686 |
| XYLT2 | xylosyltransferase II | -18.3565 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | -18.3188 |
| DCAF15 | DDB1 and CUL4 associated factor 15 | -18.2518 |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) | -18.0862 |
| SYT7 | synaptotagmin VII | -18.0269 |
| VPS51 | vacuolar protein sorting 51 homolog (S. cerevisiae) | -18.0177 |
| PNPLA4 | patatin-like phospholipase domain containing 4 | -17.8697 |
| RBPMS2 | RNA binding protein with multiple splicing 2 | -17.8697 |
| TTLL12 | tubulin tyrosine ligase-like family member 12 | -17.8356 |
