| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting CDK11 in HCT116 cell line (Study accession: SRP156201) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_6829_KD_CDK11_SRP156201 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADAM12 | ADAM metallopeptidase domain 12 | 20.0 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 20.0 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 19.301 |
| XYLT1 | xylosyltransferase I | 18.2007 |
| FAM20A | family with sequence similarity 20, member A | 17.5935 |
| LDLRAD2 | low density lipoprotein receptor class A domain containing 2 | 17.4572 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 | 16.8164 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 16.4488 |
| ADAM21 | ADAM metallopeptidase domain 21 | 14.0991 |
| ADAMTSL4 | ADAMTS-like 4 | 13.848 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) | 11.7316 |
| DLEU7 | deleted in lymphocytic leukemia, 7 | 10.8319 |
| GAS6 | growth arrest-specific 6 | 10.2377 |
| NFASC | neurofascin | 9.8191 |
| PLD4 | phospholipase D family, member 4 | 9.78085 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 9.7186 |
| MNS1 | meiosis-specific nuclear structural 1 | 9.65361 |
| C1QTNF7 | C1q and tumor necrosis factor related protein 7 | 9.55839 |
| CHTF18 | CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) | 9.53442 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 9.16749 |
| CNTN2 | contactin 2 (axonal) | 8.85261 |
| SLC25A29 | solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 | 8.74318 |
| BEST1 | bestrophin 1 | 8.53002 |
| GRIA3 | glutamate receptor, ionotropic, AMPA 3 | 7.7573 |
| SDR39U1 | short chain dehydrogenase/reductase family 39U, member 1 | 7.36987 |
| SLC51A | solute carrier family 51, alpha subunit | 7.32749 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 7.32749 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 | 7.16771 |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) | 7.08485 |
| SEPT11 | septin 11 | 7.04224 |
| TMEM215 | transmembrane protein 215 | 6.7007 |
| ARHGAP31 | Rho GTPase activating protein 31 | 6.42046 |
| DNAAF3 | dynein, axonemal, assembly factor 3 | 6.30712 |
| NNAT | neuronatin | 6.11054 |
| UBN1 | ubinuclein 1 | 6.05359 |
| COG5 | component of oligomeric golgi complex 5 | 6.02961 |
| H3F3A | H3 histone, family 3A | 5.89375 |
| SP3 | Sp3 transcription factor | 5.82407 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate | 5.74681 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 5.74201 |
| CC2D2A | coiled-coil and C2 domain containing 2A | 5.70145 |
| CNGB3 | cyclic nucleotide gated channel beta 3 | 5.55406 |
| UQCC3 | ubiquinol-cytochrome c reductase complex assembly factor 3 | 5.38838 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 5.3881 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 5.388 |
| GRM3 | glutamate receptor, metabotropic 3 | 5.38529 |
| PLK5 | polo-like kinase 5 | 5.33882 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | 5.33555 |
| TSSK3 | testis-specific serine kinase 3 | 5.25521 |
| CPM | carboxypeptidase M | 5.23155 |
| TTN | titin | 5.22015 |
| PAX8 | paired box 8 | 5.20641 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 | 5.12246 |
| KDM3A | lysine (K)-specific demethylase 3A | 5.1188 |
| ATG12 | autophagy related 12 | 4.93494 |
| METTL12 | methyltransferase like 12 | 4.9057 |
| CPLX2 | complexin 2 | 4.80826 |
| TMEM80 | transmembrane protein 80 | 4.80424 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | 4.79854 |
| RHOQ | ras homolog family member Q | 4.76486 |
| CRABP1 | cellular retinoic acid binding protein 1 | 4.62974 |
| BBIP1 | BBSome interacting protein 1 | 4.53091 |
| TFPI2 | tissue factor pathway inhibitor 2 | 4.52446 |
| GLIPR1L1 | GLI pathogenesis-related 1 like 1 | 4.48121 |
| SEPT4 | septin 4 | 4.44526 |
| MEP1B | meprin A, beta | 4.38843 |
| CDSN | corneodesmosin | 4.38553 |
| LIG3 | ligase III, DNA, ATP-dependent | 4.38243 |
| MYO1F | myosin IF | 4.2274 |
| ZNF397 | zinc finger protein 397 | 4.21673 |
| WDR24 | WD repeat domain 24 | 4.2154 |
| MYO9A | myosin IXA | 4.14675 |
| SATB1 | SATB homeobox 1 | 4.13597 |
| CSPG4 | chondroitin sulfate proteoglycan 4 | 4.12979 |
| COMMD9 | COMM domain containing 9 | 4.05016 |
| AMT | aminomethyltransferase | 4.00861 |
| RGS13 | regulator of G-protein signaling 13 | 3.97363 |
| FAM228B | family with sequence similarity 228, member B | 3.96815 |
| MLANA | melan-A | 3.96815 |
| DMXL2 | Dmx-like 2 | 3.92028 |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 | 3.88821 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 | 3.82813 |
| ZNF562 | zinc finger protein 562 | 3.7233 |
| PSTK | phosphoseryl-tRNA kinase | 3.70762 |
| SETMAR | SET domain and mariner transposase fusion gene | 3.70762 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 3.65042 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 3.64115 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 | 3.61926 |
| KCTD4 | potassium channel tetramerization domain containing 4 | 3.60707 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | 3.60707 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 | 3.55677 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | 3.55006 |
| NMT1 | N-myristoyltransferase 1 | 3.54612 |
| FMO3 | flavin containing monooxygenase 3 | 3.51658 |
| BAD | BCL2-associated agonist of cell death | 3.50235 |
| SLC38A4 | solute carrier family 38, member 4 | 3.49275 |
| TTC39A | tetratricopeptide repeat domain 39A | 3.46088 |
| RABL6 | RAB, member RAS oncogene family-like 6 | 3.44925 |
| KIAA1919 | KIAA1919 | 3.44041 |
| ZSWIM7 | zinc finger, SWIM-type containing 7 | 3.43876 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC16A4 | solute carrier family 16, member 4 | -20.0 |
| STXBP5L | syntaxin binding protein 5-like | -20.0 |
| KLC1 | kinesin light chain 1 | -20.0 |
| ENOSF1 | enolase superfamily member 1 | -18.2007 |
| TRIM13 | tripartite motif containing 13 | -17.5935 |
| UBXN6 | UBX domain protein 6 | -17.2204 |
| ZNF276 | zinc finger protein 276 | -16.4488 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -15.4012 |
| MYO1E | myosin IE | -14.7158 |
| FN1 | fibronectin 1 | -13.7796 |
| NOSTRIN | nitric oxide synthase trafficking | -12.3537 |
| EXOSC9 | exosome component 9 | -12.2766 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -12.1246 |
| TRIM59 | tripartite motif containing 59 | -12.0969 |
| LRRC41 | leucine rich repeat containing 41 | -11.6192 |
| KIF7 | kinesin family member 7 | -11.6108 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -11.5504 |
| KIAA0895 | KIAA0895 | -11.276 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | -11.1457 |
| CCL15 | chemokine (C-C motif) ligand 15 | -10.8319 |
| HIST1H2BN | histone cluster 1, H2bn | -10.7371 |
| TPPP | tubulin polymerization promoting protein | -10.5856 |
| INTS8 | integrator complex subunit 8 | -10.5856 |
| ASB18 | ankyrin repeat and SOCS box containing 18 | -10.392 |
| MTFR1L | mitochondrial fission regulator 1-like | -10.3228 |
| IGSF10 | immunoglobulin superfamily, member 10 | -10.1919 |
| CCDC107 | coiled-coil domain containing 107 | -10.0289 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | -9.65814 |
| CSNK1D | casein kinase 1, delta | -9.57323 |
| FBXO11 | F-box protein 11 | -9.02693 |
| PAQR4 | progestin and adipoQ receptor family member IV | -8.85261 |
| TMEM198 | transmembrane protein 198 | -8.73884 |
| WSB2 | WD repeat and SOCS box containing 2 | -8.712 |
| FRMD5 | FERM domain containing 5 | -8.4692 |
| PTOV1 | prostate tumor overexpressed 1 | -8.19431 |
| ADCY3 | adenylate cyclase 3 | -7.96234 |
| FAM166A | family with sequence similarity 166, member A | -7.88296 |
| GCC1 | GRIP and coiled-coil domain containing 1 | -7.61853 |
| SYNGR2 | synaptogyrin 2 | -7.57642 |
| JAM3 | junctional adhesion molecule 3 | -7.43797 |
| SLFNL1 | schlafen-like 1 | -7.42522 |
| PHYKPL | 5-phosphohydroxy-L-lysine phospho-lyase | -7.38259 |
| RBM12B | RNA binding motif protein 12B | -7.33573 |
| CEMP1 | cementum protein 1 | -7.28033 |
| CIRBP | cold inducible RNA binding protein | -7.08434 |
| STK17A | serine/threonine kinase 17a | -7.04983 |
| GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C | -6.97518 |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 | -6.97118 |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa | -6.89333 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | -6.88923 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | -6.87479 |
| FANCD2OS | FANCD2 opposite strand | -6.85818 |
| OSBPL10 | oxysterol binding protein-like 10 | -6.85392 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | -6.68214 |
| ZNF750 | zinc finger protein 750 | -6.38548 |
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | -6.2942 |
| TP53INP1 | tumor protein p53 inducible nuclear protein 1 | -6.02742 |
| RMDN3 | regulator of microtubule dynamics 3 | -6.00726 |
| FAM149B1 | family with sequence similarity 149, member B1 | -6.00098 |
| COX20 | COX20 cytochrome c oxidase assembly factor | -5.96699 |
| SYNC | syncoilin, intermediate filament protein | -5.93758 |
| BMP6 | bone morphogenetic protein 6 | -5.86887 |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 | -5.86432 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | -5.85223 |
| KCNRG | potassium channel regulator | -5.82407 |
| ABI2 | abl-interactor 2 | -5.80608 |
| TMBIM4 | transmembrane BAX inhibitor motif containing 4 | -5.5794 |
| LAT2 | linker for activation of T cells family, member 2 | -5.46145 |
| DIS3L | DIS3 like exosome 3'-5' exoribonuclease | -5.3881 |
| FILIP1L | filamin A interacting protein 1-like | -5.38529 |
| CTSB | cathepsin B | -5.31091 |
| THBS3 | thrombospondin 3 | -5.22015 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase | -5.22015 |
| IQCA1 | IQ motif containing with AAA domain 1 | -5.20939 |
| DCLRE1C | DNA cross-link repair 1C | -5.12956 |
| RPS29 | ribosomal protein S29 | -5.03578 |
| POLG | polymerase (DNA directed), gamma | -4.94618 |
| CLDN2 | claudin 2 | -4.93808 |
| P2RY12 | purinergic receptor P2Y, G-protein coupled, 12 | -4.93536 |
| C12ORF65 | chromosome 12 open reading frame 65 | -4.87523 |
| SLC7A6OS | solute carrier family 7, member 6 opposite strand | -4.86437 |
| ZNF654 | zinc finger protein 654 | -4.85684 |
| LRRC59 | leucine rich repeat containing 59 | -4.83737 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -4.82075 |
| KRT8 | keratin 8, type II | -4.75654 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -4.73645 |
| PINK1 | PTEN induced putative kinase 1 | -4.715 |
| C14ORF79 | chromosome 14 open reading frame 79 | -4.68985 |
| SERPINA10 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 | -4.65366 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -4.62974 |
| CREB1 | cAMP responsive element binding protein 1 | -4.57575 |
| HHLA2 | HERV-H LTR-associating 2 | -4.56056 |
| GPR171 | G protein-coupled receptor 171 | -4.53801 |
| RUFY1 | RUN and FYVE domain containing 1 | -4.52163 |
| SPDYE3 | speedy/RINGO cell cycle regulator family member E3 | -4.51564 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -4.48693 |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase | -4.47688 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -4.46204 |
| TRAPPC4 | trafficking protein particle complex 4 | -4.43771 |
| FAM134C | family with sequence similarity 134, member C | -4.4288 |
