Perturb_6880_KO_MUC3A_SRP371276 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KO perturbation targeting MUC3A in HCT116 cell line (Study accession: SRP371276) (PerturbAtlas)
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Genes

33 genes differentially expressed following the Perturb_6880_KO_MUC3A_SRP371276 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
DKK4 dickkopf WNT signaling pathway inhibitor 4 6.8197
DHRS2 dehydrogenase/reductase (SDR family) member 2 6.8197
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 6.65737
SLC16A6 solute carrier family 16, member 6 4.21765
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 4.16975
KRT5 keratin 5, type II 3.95345
PARP10 poly (ADP-ribose) polymerase family, member 10 3.95345
RERG RAS-like, estrogen-regulated, growth inhibitor 3.93633
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 2.90539
KRT23 keratin 23, type I 2.61635
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 2.59323
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 1.82312
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 1.4932
ZNF804A zinc finger protein 804A 1.47083
APOL6 apolipoprotein L, 6 1.43851
KRT13 keratin 13, type I 1.42118
OASL 2'-5'-oligoadenylate synthetase-like 1.38315
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 1.31264

decreased expression

Symbol Name Standardized Value
ICAM1 intercellular adhesion molecule 1 -6.8197
PVRL3 poliovirus receptor-related 3 -5.47693
HNF1B HNF1 homeobox B -4.56644
DIAPH2 diaphanous-related formin 2 -4.21765
ZNF426 zinc finger protein 426 -3.93633
LARGE like-glycosyltransferase -3.93633
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 -3.3531
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -3.34946
KRT7 keratin 7, type II -3.04782
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -2.3569
NAV3 neuron navigator 3 -1.90264
TENM3 teneurin transmembrane protein 3 -1.87982
PPAP2B phosphatidic acid phosphatase type 2B -1.44307
RGS2 regulator of G-protein signaling 2 -1.38315
CPEB2 cytoplasmic polyadenylation element binding protein 2 -1.38315