| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting SETDB1 in acute myeloid leukemia cell THP-1 cell line (Study accession: SRP116955) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_707_KD_SETDB1_SRP116955 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MROH1 | maestro heat-like repeat family member 1 | 20.0 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 20.0 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 | 20.0 |
| TNK2 | tyrosine kinase, non-receptor, 2 | 20.0 |
| SON | SON DNA binding protein | 20.0 |
| GAK | cyclin G associated kinase | 20.0 |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) | 20.0 |
| FAM46A | family with sequence similarity 46, member A | 20.0 |
| MOV10 | Mov10 RISC complex RNA helicase | 20.0 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 20.0 |
| IFITM1 | interferon induced transmembrane protein 1 | 20.0 |
| SCARB2 | scavenger receptor class B, member 2 | 20.0 |
| IFI44L | interferon-induced protein 44-like | 20.0 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 | 20.0 |
| WSB1 | WD repeat and SOCS box containing 1 | 20.0 |
| SPP1 | secreted phosphoprotein 1 | 20.0 |
| SFMBT2 | Scm-like with four mbt domains 2 | 20.0 |
| TNS3 | tensin 3 | 20.0 |
| CA2 | carbonic anhydrase II | 20.0 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 20.0 |
| TGFB1 | transforming growth factor, beta 1 | 20.0 |
| PLXNB2 | plexin B2 | 20.0 |
| PML | promyelocytic leukemia | 20.0 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 20.0 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 20.0 |
| RNF213 | ring finger protein 213 | 20.0 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 20.0 |
| FURIN | furin (paired basic amino acid cleaving enzyme) | 20.0 |
| SETX | senataxin | 20.0 |
| FRY | furry homolog (Drosophila) | 20.0 |
| KIAA1551 | KIAA1551 | 20.0 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 20.0 |
| ABR | active BCR-related | 20.0 |
| EMILIN2 | elastin microfibril interfacer 2 | 20.0 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 20.0 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 20.0 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 20.0 |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 20.0 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 20.0 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 20.0 |
| PLEC | plectin | 20.0 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 20.0 |
| IL4I1 | interleukin 4 induced 1 | 20.0 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | 20.0 |
| P2RY8 | purinergic receptor P2Y, G-protein coupled, 8 | 20.0 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 20.0 |
| PTPRC | protein tyrosine phosphatase, receptor type, C | 20.0 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 20.0 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 20.0 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 20.0 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 20.0 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 20.0 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 20.0 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | 20.0 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 20.0 |
| ADGRA2 | adhesion G protein-coupled receptor A2 | 20.0 |
| NLRC5 | NLR family, CARD domain containing 5 | 20.0 |
| SHOX2 | short stature homeobox 2 | 20.0 |
| TXNIP | thioredoxin interacting protein | 20.0 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 20.0 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 20.0 |
| VAV1 | vav 1 guanine nucleotide exchange factor | 20.0 |
| CTSB | cathepsin B | 20.0 |
| CTSL | cathepsin L | 20.0 |
| IGF2R | insulin-like growth factor 2 receptor | 20.0 |
| CFD | complement factor D (adipsin) | 20.0 |
| ZNF117 | zinc finger protein 117 | 20.0 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 20.0 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 20.0 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 | 20.0 |
| INSL3 | insulin-like 3 (Leydig cell) | 20.0 |
| NOTCH1 | notch 1 | 20.0 |
| NOTCH2 | notch 2 | 20.0 |
| SIPA1 | signal-induced proliferation-associated 1 | 20.0 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 20.0 |
| IFIH1 | interferon induced with helicase C domain 1 | 20.0 |
| PPP6R1 | protein phosphatase 6, regulatory subunit 1 | 20.0 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 20.0 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 20.0 |
| ENG | endoglin | 20.0 |
| DGKZ | diacylglycerol kinase, zeta | 20.0 |
| MYO9B | myosin IXB | 20.0 |
| NBEAL2 | neurobeachin-like 2 | 20.0 |
| TMC6 | transmembrane channel-like 6 | 20.0 |
| CLCN7 | chloride channel, voltage-sensitive 7 | 20.0 |
| ANKRD11 | ankyrin repeat domain 11 | 20.0 |
| JMJD1C | jumonji domain containing 1C | 20.0 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 20.0 |
| SLC38A10 | solute carrier family 38, member 10 | 20.0 |
| AGRN | agrin | 20.0 |
| PRAME | preferentially expressed antigen in melanoma | 20.0 |
| MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | 20.0 |
| TNRC18 | trinucleotide repeat containing 18 | 20.0 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 20.0 |
| SZT2 | seizure threshold 2 homolog (mouse) | 20.0 |
| GPNMB | glycoprotein (transmembrane) nmb | 20.0 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 20.0 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 20.0 |
| GMIP | GEM interacting protein | 20.0 |
| SEC24D | SEC24 family member D | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MMP24-AS1 | MMP24 antisense RNA 1 | -20.0 |
| CNN3 | calponin 3, acidic | -20.0 |
| BCL7C | B-cell CLL/lymphoma 7C | -20.0 |
| NUDT8 | nudix (nucleoside diphosphate linked moiety X)-type motif 8 | -20.0 |
| NINJ2 | ninjurin 2 | -20.0 |
| MINOS1 | mitochondrial inner membrane organizing system 1 | -20.0 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | -20.0 |
| LINC00116 | long intergenic non-protein coding RNA 116 | -20.0 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -20.0 |
| GAL | galanin/GMAP prepropeptide | -20.0 |
| FLYWCH2 | FLYWCH family member 2 | -20.0 |
| SFXN2 | sideroflexin 2 | -20.0 |
| PSENEN | presenilin enhancer gamma secretase subunit | -20.0 |
| UQCRHL | ubiquinol-cytochrome c reductase hinge protein-like | -20.0 |
| C1S | complement component 1, s subcomponent | -20.0 |
| CCDC34 | coiled-coil domain containing 34 | -20.0 |
| NEUROG3 | neurogenin 3 | -20.0 |
| RPL26L1 | ribosomal protein L26-like 1 | -20.0 |
| RPL39 | ribosomal protein L39 | -20.0 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -20.0 |
| NKG7 | natural killer cell granule protein 7 | -20.0 |
| GUCY2C | guanylate cyclase 2C | -20.0 |
| PMF1 | polyamine-modulated factor 1 | -20.0 |
| C12ORF75 | chromosome 12 open reading frame 75 | -20.0 |
| MOCS2 | molybdenum cofactor synthesis 2 | -20.0 |
| AGMAT | agmatine ureohydrolase (agmatinase) | -20.0 |
| C12ORF57 | chromosome 12 open reading frame 57 | -20.0 |
| UTS2 | urotensin 2 | -20.0 |
| PTRHD1 | peptidyl-tRNA hydrolase domain containing 1 | -20.0 |
| ANAPC15 | anaphase promoting complex subunit 15 | -20.0 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -20.0 |
| DTD1 | D-tyrosyl-tRNA deacylase 1 | -20.0 |
| RAB37 | RAB37, member RAS oncogene family | -20.0 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 | -20.0 |
| TBC1D30 | TBC1 domain family, member 30 | -20.0 |
| DUSP9 | dual specificity phosphatase 9 | -20.0 |
| NDUFC2 | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa | -20.0 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | -20.0 |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | -20.0 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 | -20.0 |
| MVK | mevalonate kinase | -20.0 |
| TMEM14A | transmembrane protein 14A | -20.0 |
| TMEM141 | transmembrane protein 141 | -20.0 |
| LYRM4 | LYR motif containing 4 | -20.0 |
| CISD1 | CDGSH iron sulfur domain 1 | -20.0 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | -20.0 |
| CETN2 | centrin, EF-hand protein, 2 | -20.0 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | -20.0 |
| CKM | creatine kinase, muscle | -20.0 |
| ALDOC | aldolase C, fructose-bisphosphate | -20.0 |
| FAM64A | family with sequence similarity 64, member A | -20.0 |
| TNF | tumor necrosis factor | -20.0 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -20.0 |
| SYN3 | synapsin III | -20.0 |
| RBFA | ribosome binding factor A (putative) | -20.0 |
| SEMG1 | semenogelin I | -20.0 |
| CCL22 | chemokine (C-C motif) ligand 22 | -20.0 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 | -20.0 |
| CCDC58 | coiled-coil domain containing 58 | -20.0 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -20.0 |
| MRPL48 | mitochondrial ribosomal protein L48 | -20.0 |
| NRM | nurim (nuclear envelope membrane protein) | -20.0 |
| C3ORF14 | chromosome 3 open reading frame 14 | -20.0 |
| NREP | neuronal regeneration related protein | -20.0 |
| MARC1 | mitochondrial amidoxime reducing component 1 | -20.0 |
| RNF175 | ring finger protein 175 | -20.0 |
| TESC | tescalcin | -20.0 |
| CRABP1 | cellular retinoic acid binding protein 1 | -20.0 |
| CHCHD5 | coiled-coil-helix-coiled-coil-helix domain containing 5 | -20.0 |
| LINC01420 | long intergenic non-protein coding RNA 1420 | -20.0 |
| IGSF6 | immunoglobulin superfamily, member 6 | -20.0 |
| CDCA3 | cell division cycle associated 3 | -20.0 |
| FAM72C | family with sequence similarity 72, member C | -20.0 |
| MIEN1 | migration and invasion enhancer 1 | -20.0 |
| SVIP | small VCP/p97-interacting protein | -20.0 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | -20.0 |
| ANXA8 | annexin A8 | -20.0 |
| MEST | mesoderm specific transcript | -20.0 |
| ALG14 | ALG14, UDP-N-acetylglucosaminyltransferase subunit | -20.0 |
| DPY30 | dpy-30 homolog (C. elegans) | -20.0 |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 | -20.0 |
| BOLA3 | bolA family member 3 | -20.0 |
| NDUFB8 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa | -20.0 |
| C2ORF76 | chromosome 2 open reading frame 76 | -20.0 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) | -20.0 |
| MPO | myeloperoxidase | -20.0 |
| PIF1 | PIF1 5'-to-3' DNA helicase | -20.0 |
| CDC25C | cell division cycle 25C | -20.0 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -20.0 |
| TMEM54 | transmembrane protein 54 | -20.0 |
| TMEM53 | transmembrane protein 53 | -20.0 |
| MT1G | metallothionein 1G | -20.0 |
| SAAL1 | serum amyloid A-like 1 | -20.0 |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 | -20.0 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex III subunit XI | -20.0 |
| ADM2 | adrenomedullin 2 | -20.0 |
| C15ORF41 | chromosome 15 open reading frame 41 | -20.0 |
| DCAKD | dephospho-CoA kinase domain containing | -20.0 |
| CCDC167 | coiled-coil domain containing 167 | -20.0 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -20.0 |
