| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | OE perturbation targeting CDH1 in HEK293T.rKSHV219 cell line (Study accession: SRP279053) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_7187_OE_CDH1_SRP279053 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POLR1A | polymerase (RNA) I polypeptide A, 194kDa | 20.0 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 20.0 |
| ZNF518B | zinc finger protein 518B | 20.0 |
| INA | internexin neuronal intermediate filament protein, alpha | 20.0 |
| EIF5 | eukaryotic translation initiation factor 5 | 20.0 |
| CYLD | cylindromatosis (turban tumor syndrome) | 20.0 |
| SLC30A6 | solute carrier family 30 (zinc transporter), member 6 | 20.0 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 20.0 |
| MICALL1 | MICAL-like 1 | 20.0 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 20.0 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 20.0 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 20.0 |
| SHISA2 | shisa family member 2 | 20.0 |
| GCC1 | GRIP and coiled-coil domain containing 1 | 20.0 |
| SETD7 | SET domain containing (lysine methyltransferase) 7 | 20.0 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 20.0 |
| DCLRE1A | DNA cross-link repair 1A | 20.0 |
| EFNB2 | ephrin-B2 | 20.0 |
| DBNL | drebrin-like | 20.0 |
| RRP1B | ribosomal RNA processing 1B | 20.0 |
| RRP15 | ribosomal RNA processing 15 homolog (S. cerevisiae) | 20.0 |
| BRCA1 | breast cancer 1, early onset | 20.0 |
| BRCA2 | breast cancer 2, early onset | 20.0 |
| FAM208A | family with sequence similarity 208, member A | 20.0 |
| PRMT6 | protein arginine methyltransferase 6 | 20.0 |
| UMPS | uridine monophosphate synthetase | 20.0 |
| TOP3A | topoisomerase (DNA) III alpha | 20.0 |
| CENPB | centromere protein B, 80kDa | 20.0 |
| ZNF512B | zinc finger protein 512B | 20.0 |
| MRPL36 | mitochondrial ribosomal protein L36 | 20.0 |
| SLC35A4 | solute carrier family 35, member A4 | 20.0 |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like | 20.0 |
| SEPHS2 | selenophosphate synthetase 2 | 20.0 |
| IKBIP | IKBKB interacting protein | 20.0 |
| RCAN1 | regulator of calcineurin 1 | 20.0 |
| DARS2 | aspartyl-tRNA synthetase 2, mitochondrial | 20.0 |
| FAM178A | family with sequence similarity 178, member A | 20.0 |
| CTH | cystathionine gamma-lyase | 20.0 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 20.0 |
| E2F7 | E2F transcription factor 7 | 20.0 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 20.0 |
| JOSD1 | Josephin domain containing 1 | 20.0 |
| SMARCAD1 | SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 | 20.0 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | 20.0 |
| E2F3 | E2F transcription factor 3 | 20.0 |
| E2F2 | E2F transcription factor 2 | 20.0 |
| CDC6 | cell division cycle 6 | 20.0 |
| CDC7 | cell division cycle 7 | 20.0 |
| WDR35 | WD repeat domain 35 | 20.0 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 20.0 |
| ITGAV | integrin, alpha V | 20.0 |
| HSPA4L | heat shock 70kDa protein 4-like | 20.0 |
| GTF2H1 | general transcription factor IIH, polypeptide 1, 62kDa | 20.0 |
| SLC38A1 | solute carrier family 38, member 1 | 20.0 |
| NCOA5 | nuclear receptor coactivator 5 | 20.0 |
| MESDC1 | mesoderm development candidate 1 | 20.0 |
| ZNF274 | zinc finger protein 274 | 20.0 |
| ANTXR1 | anthrax toxin receptor 1 | 20.0 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 | 20.0 |
| PCDH10 | protocadherin 10 | 20.0 |
| ZNF629 | zinc finger protein 629 | 20.0 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 20.0 |
| ZNF655 | zinc finger protein 655 | 20.0 |
| NOTCH3 | notch 3 | 20.0 |
| IGF2R | insulin-like growth factor 2 receptor | 20.0 |
| TDG | thymine-DNA glycosylase | 20.0 |
| BTG2 | BTG family, member 2 | 20.0 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 | 20.0 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 20.0 |
| TGS1 | trimethylguanosine synthase 1 | 20.0 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 | 20.0 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 20.0 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 20.0 |
| NOTCH2 | notch 2 | 20.0 |
| C9ORF64 | chromosome 9 open reading frame 64 | 20.0 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 20.0 |
| FER | fer (fps/fes related) tyrosine kinase | 20.0 |
| TMEM45A | transmembrane protein 45A | 20.0 |
| RASEF | RAS and EF-hand domain containing | 20.0 |
| MEGF8 | multiple EGF-like-domains 8 | 20.0 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 20.0 |
| MIS12 | MIS12 kinetochore complex component | 20.0 |
| SLC38A10 | solute carrier family 38, member 10 | 20.0 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa | 20.0 |
| ZNF644 | zinc finger protein 644 | 20.0 |
| GPRASP2 | G protein-coupled receptor associated sorting protein 2 | 20.0 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 20.0 |
| ZC3H4 | zinc finger CCCH-type containing 4 | 20.0 |
| QSER1 | glutamine and serine rich 1 | 20.0 |
| DENND4A | DENN/MADD domain containing 4A | 20.0 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 | 20.0 |
| OGFRL1 | opioid growth factor receptor-like 1 | 20.0 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 20.0 |
| NCR3LG1 | natural killer cell cytotoxicity receptor 3 ligand 1 | 20.0 |
| MEPCE | methylphosphate capping enzyme | 20.0 |
| PRNP | prion protein | 20.0 |
| FZD6 | frizzled class receptor 6 | 20.0 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 20.0 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 20.0 |
| SESN2 | sestrin 2 | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | -20.0 |
| THAP3 | THAP domain containing, apoptosis associated protein 3 | -20.0 |
| TMEM120A | transmembrane protein 120A | -20.0 |
| PPARG | peroxisome proliferator-activated receptor gamma | -20.0 |
| BNIP1 | BCL2/adenovirus E1B 19kDa interacting protein 1 | -20.0 |
| MVD | mevalonate (diphospho) decarboxylase | -20.0 |
| IAH1 | isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) | -20.0 |
| CRYAB | crystallin, alpha B | -20.0 |
| CCDC112 | coiled-coil domain containing 112 | -20.0 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L | -20.0 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | -20.0 |
| RRAS | related RAS viral (r-ras) oncogene homolog | -20.0 |
| CPT1C | carnitine palmitoyltransferase 1C | -20.0 |
| FRMD1 | FERM domain containing 1 | -20.0 |
| RPL39 | ribosomal protein L39 | -20.0 |
| STK3 | serine/threonine kinase 3 | -20.0 |
| CAT | catalase | -20.0 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) | -20.0 |
| RAB3A | RAB3A, member RAS oncogene family | -20.0 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 | -20.0 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -20.0 |
| ARHGAP33 | Rho GTPase activating protein 33 | -20.0 |
| MATK | megakaryocyte-associated tyrosine kinase | -20.0 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -20.0 |
| SLC22A17 | solute carrier family 22, member 17 | -20.0 |
| TOP1MT | topoisomerase (DNA) I, mitochondrial | -20.0 |
| ANKRD13D | ankyrin repeat domain 13 family, member D | -20.0 |
| MVB12A | multivesicular body subunit 12A | -20.0 |
| GYLTL1B | glycosyltransferase-like 1B | -20.0 |
| LSM12 | LSM12 homolog (S. cerevisiae) | -20.0 |
| DTD1 | D-tyrosyl-tRNA deacylase 1 | -20.0 |
| UNC119 | unc-119 homolog (C. elegans) | -20.0 |
| ZNF449 | zinc finger protein 449 | -20.0 |
| RPL23 | ribosomal protein L23 | -20.0 |
| HUS1 | HUS1 checkpoint homolog (S. pombe) | -20.0 |
| YPEL2 | yippee-like 2 (Drosophila) | -20.0 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -20.0 |
| OST4 | oligosaccharyltransferase 4 homolog (S. cerevisiae) | -20.0 |
| GKAP1 | G kinase anchoring protein 1 | -20.0 |
| KLF11 | Kruppel-like factor 11 | -20.0 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | -20.0 |
| TMEM59L | transmembrane protein 59-like | -20.0 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | -20.0 |
| RPS10 | ribosomal protein S10 | -20.0 |
| RPS17 | ribosomal protein S17 | -20.0 |
| IFT20 | intraflagellar transport 20 | -20.0 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -20.0 |
| CRAT | carnitine O-acetyltransferase | -20.0 |
| FBXO44 | F-box protein 44 | -20.0 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -20.0 |
| SGSM3 | small G protein signaling modulator 3 | -20.0 |
| PHF1 | PHD finger protein 1 | -20.0 |
| DRD4 | dopamine receptor D4 | -20.0 |
| CDHR5 | cadherin-related family member 5 | -20.0 |
| FHL2 | four and a half LIM domains 2 | -20.0 |
| MT2A | metallothionein 2A | -20.0 |
| ZFAND2B | zinc finger, AN1-type domain 2B | -20.0 |
| RGS10 | regulator of G-protein signaling 10 | -20.0 |
| MZT2B | mitotic spindle organizing protein 2B | -20.0 |
| GAB2 | GRB2-associated binding protein 2 | -20.0 |
| KRTAP19-1 | keratin associated protein 19-1 | -20.0 |
| RABAC1 | Rab acceptor 1 (prenylated) | -20.0 |
| ALKBH7 | alkB, alkylation repair homolog 7 (E. coli) | -20.0 |
| LIN7B | lin-7 homolog B (C. elegans) | -20.0 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 | -20.0 |
| EXD3 | exonuclease 3'-5' domain containing 3 | -20.0 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) | -20.0 |
| ALG3 | ALG3, alpha-1,3- mannosyltransferase | -20.0 |
| PPA2 | pyrophosphatase (inorganic) 2 | -20.0 |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A | -20.0 |
| CHCHD6 | coiled-coil-helix-coiled-coil-helix domain containing 6 | -20.0 |
| GSTA4 | glutathione S-transferase alpha 4 | -20.0 |
| GS1-259H13.2 | transmembrane protein 225-like | -20.0 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -20.0 |
| BIN1 | bridging integrator 1 | -20.0 |
| FAM132A | family with sequence similarity 132, member A | -20.0 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 | -20.0 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -20.0 |
| MAST1 | microtubule associated serine/threonine kinase 1 | -20.0 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -20.0 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | -20.0 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -20.0 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -20.0 |
| MSI1 | musashi RNA-binding protein 1 | -20.0 |
| ZNF692 | zinc finger protein 692 | -20.0 |
| PCGF1 | polycomb group ring finger 1 | -20.0 |
| TMSB15A | thymosin beta 15a | -20.0 |
| DLG4 | discs, large homolog 4 (Drosophila) | -20.0 |
| CCDC167 | coiled-coil domain containing 167 | -20.0 |
| ATP5I | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E | -20.0 |
| LIG3 | ligase III, DNA, ATP-dependent | -20.0 |
| CSAD | cysteine sulfinic acid decarboxylase | -20.0 |
| ANKRD37 | ankyrin repeat domain 37 | -20.0 |
| FADS3 | fatty acid desaturase 3 | -20.0 |
| MAN2B1 | mannosidase, alpha, class 2B, member 1 | -20.0 |
| MED30 | mediator complex subunit 30 | -20.0 |
| MXD3 | MAX dimerization protein 3 | -20.0 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | -20.0 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | -20.0 |
| DTNB | dystrobrevin, beta | -20.0 |