Perturb_7187_OE_CDH1_SRP279053 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description OE perturbation targeting CDH1 in HEK293T.rKSHV219 cell line (Study accession: SRP279053) (PerturbAtlas)
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Genes

200 genes differentially expressed following the Perturb_7187_OE_CDH1_SRP279053 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
POLR1A polymerase (RNA) I polypeptide A, 194kDa 20.0
ASCC3 activating signal cointegrator 1 complex subunit 3 20.0
ZNF518B zinc finger protein 518B 20.0
INA internexin neuronal intermediate filament protein, alpha 20.0
EIF5 eukaryotic translation initiation factor 5 20.0
CYLD cylindromatosis (turban tumor syndrome) 20.0
SLC30A6 solute carrier family 30 (zinc transporter), member 6 20.0
PPP1R10 protein phosphatase 1, regulatory subunit 10 20.0
MICALL1 MICAL-like 1 20.0
IFNAR1 interferon (alpha, beta and omega) receptor 1 20.0
DCBLD2 discoidin, CUB and LCCL domain containing 2 20.0
TGFBR1 transforming growth factor, beta receptor 1 20.0
SHISA2 shisa family member 2 20.0
GCC1 GRIP and coiled-coil domain containing 1 20.0
SETD7 SET domain containing (lysine methyltransferase) 7 20.0
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 20.0
DCLRE1A DNA cross-link repair 1A 20.0
EFNB2 ephrin-B2 20.0
DBNL drebrin-like 20.0
RRP1B ribosomal RNA processing 1B 20.0
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) 20.0
BRCA1 breast cancer 1, early onset 20.0
BRCA2 breast cancer 2, early onset 20.0
FAM208A family with sequence similarity 208, member A 20.0
PRMT6 protein arginine methyltransferase 6 20.0
UMPS uridine monophosphate synthetase 20.0
TOP3A topoisomerase (DNA) III alpha 20.0
CENPB centromere protein B, 80kDa 20.0
ZNF512B zinc finger protein 512B 20.0
MRPL36 mitochondrial ribosomal protein L36 20.0
SLC35A4 solute carrier family 35, member A4 20.0
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like 20.0
SEPHS2 selenophosphate synthetase 2 20.0
IKBIP IKBKB interacting protein 20.0
RCAN1 regulator of calcineurin 1 20.0
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 20.0
FAM178A family with sequence similarity 178, member A 20.0
CTH cystathionine gamma-lyase 20.0
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 20.0
E2F7 E2F transcription factor 7 20.0
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 20.0
JOSD1 Josephin domain containing 1 20.0
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 20.0
ELF1 E74-like factor 1 (ets domain transcription factor) 20.0
E2F3 E2F transcription factor 3 20.0
E2F2 E2F transcription factor 2 20.0
CDC6 cell division cycle 6 20.0
CDC7 cell division cycle 7 20.0
WDR35 WD repeat domain 35 20.0
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 20.0
ITGAV integrin, alpha V 20.0
HSPA4L heat shock 70kDa protein 4-like 20.0
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 20.0
SLC38A1 solute carrier family 38, member 1 20.0
NCOA5 nuclear receptor coactivator 5 20.0
MESDC1 mesoderm development candidate 1 20.0
ZNF274 zinc finger protein 274 20.0
ANTXR1 anthrax toxin receptor 1 20.0
ZCCHC14 zinc finger, CCHC domain containing 14 20.0
PCDH10 protocadherin 10 20.0
ZNF629 zinc finger protein 629 20.0
KCTD12 potassium channel tetramerization domain containing 12 20.0
ZNF655 zinc finger protein 655 20.0
NOTCH3 notch 3 20.0
IGF2R insulin-like growth factor 2 receptor 20.0
TDG thymine-DNA glycosylase 20.0
BTG2 BTG family, member 2 20.0
LRIF1 ligand dependent nuclear receptor interacting factor 1 20.0
KIDINS220 kinase D-interacting substrate, 220kDa 20.0
TGS1 trimethylguanosine synthase 1 20.0
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 20.0
ASXL2 additional sex combs like transcriptional regulator 2 20.0
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 20.0
NOTCH2 notch 2 20.0
C9ORF64 chromosome 9 open reading frame 64 20.0
SYNE1 spectrin repeat containing, nuclear envelope 1 20.0
FER fer (fps/fes related) tyrosine kinase 20.0
TMEM45A transmembrane protein 45A 20.0
RASEF RAS and EF-hand domain containing 20.0
MEGF8 multiple EGF-like-domains 8 20.0
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 20.0
MIS12 MIS12 kinetochore complex component 20.0
SLC38A10 solute carrier family 38, member 10 20.0
GTF2A1 general transcription factor IIA, 1, 19/37kDa 20.0
ZNF644 zinc finger protein 644 20.0
GPRASP2 G protein-coupled receptor associated sorting protein 2 20.0
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain 20.0
ZC3H4 zinc finger CCCH-type containing 4 20.0
QSER1 glutamine and serine rich 1 20.0
DENND4A DENN/MADD domain containing 4A 20.0
PHLDA3 pleckstrin homology-like domain, family A, member 3 20.0
OGFRL1 opioid growth factor receptor-like 1 20.0
NSD1 nuclear receptor binding SET domain protein 1 20.0
NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1 20.0
MEPCE methylphosphate capping enzyme 20.0
PRNP prion protein 20.0
FZD6 frizzled class receptor 6 20.0
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 20.0
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 20.0
SESN2 sestrin 2 20.0

decreased expression

Symbol Name Standardized Value
GPD1L glycerol-3-phosphate dehydrogenase 1-like -20.0
THAP3 THAP domain containing, apoptosis associated protein 3 -20.0
TMEM120A transmembrane protein 120A -20.0
PPARG peroxisome proliferator-activated receptor gamma -20.0
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 -20.0
MVD mevalonate (diphospho) decarboxylase -20.0
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) -20.0
CRYAB crystallin, alpha B -20.0
CCDC112 coiled-coil domain containing 112 -20.0
PIGL phosphatidylinositol glycan anchor biosynthesis, class L -20.0
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -20.0
RRAS related RAS viral (r-ras) oncogene homolog -20.0
CPT1C carnitine palmitoyltransferase 1C -20.0
FRMD1 FERM domain containing 1 -20.0
RPL39 ribosomal protein L39 -20.0
STK3 serine/threonine kinase 3 -20.0
CAT catalase -20.0
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) -20.0
RAB3A RAB3A, member RAS oncogene family -20.0
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 -20.0
LCORL ligand dependent nuclear receptor corepressor-like -20.0
ARHGAP33 Rho GTPase activating protein 33 -20.0
MATK megakaryocyte-associated tyrosine kinase -20.0
NME2 NME/NM23 nucleoside diphosphate kinase 2 -20.0
SLC22A17 solute carrier family 22, member 17 -20.0
TOP1MT topoisomerase (DNA) I, mitochondrial -20.0
ANKRD13D ankyrin repeat domain 13 family, member D -20.0
MVB12A multivesicular body subunit 12A -20.0
GYLTL1B glycosyltransferase-like 1B -20.0
LSM12 LSM12 homolog (S. cerevisiae) -20.0
DTD1 D-tyrosyl-tRNA deacylase 1 -20.0
UNC119 unc-119 homolog (C. elegans) -20.0
ZNF449 zinc finger protein 449 -20.0
RPL23 ribosomal protein L23 -20.0
HUS1 HUS1 checkpoint homolog (S. pombe) -20.0
YPEL2 yippee-like 2 (Drosophila) -20.0
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -20.0
OST4 oligosaccharyltransferase 4 homolog (S. cerevisiae) -20.0
GKAP1 G kinase anchoring protein 1 -20.0
KLF11 Kruppel-like factor 11 -20.0
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -20.0
TMEM59L transmembrane protein 59-like -20.0
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -20.0
RPS10 ribosomal protein S10 -20.0
RPS17 ribosomal protein S17 -20.0
IFT20 intraflagellar transport 20 -20.0
EIF4A1 eukaryotic translation initiation factor 4A1 -20.0
CRAT carnitine O-acetyltransferase -20.0
FBXO44 F-box protein 44 -20.0
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -20.0
SGSM3 small G protein signaling modulator 3 -20.0
PHF1 PHD finger protein 1 -20.0
DRD4 dopamine receptor D4 -20.0
CDHR5 cadherin-related family member 5 -20.0
FHL2 four and a half LIM domains 2 -20.0
MT2A metallothionein 2A -20.0
ZFAND2B zinc finger, AN1-type domain 2B -20.0
RGS10 regulator of G-protein signaling 10 -20.0
MZT2B mitotic spindle organizing protein 2B -20.0
GAB2 GRB2-associated binding protein 2 -20.0
KRTAP19-1 keratin associated protein 19-1 -20.0
RABAC1 Rab acceptor 1 (prenylated) -20.0
ALKBH7 alkB, alkylation repair homolog 7 (E. coli) -20.0
LIN7B lin-7 homolog B (C. elegans) -20.0
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 -20.0
EXD3 exonuclease 3'-5' domain containing 3 -20.0
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) -20.0
ALG3 ALG3, alpha-1,3- mannosyltransferase -20.0
PPA2 pyrophosphatase (inorganic) 2 -20.0
HIGD2A HIG1 hypoxia inducible domain family, member 2A -20.0
CHCHD6 coiled-coil-helix-coiled-coil-helix domain containing 6 -20.0
GSTA4 glutathione S-transferase alpha 4 -20.0
GS1-259H13.2 transmembrane protein 225-like -20.0
AUH AU RNA binding protein/enoyl-CoA hydratase -20.0
BIN1 bridging integrator 1 -20.0
FAM132A family with sequence similarity 132, member A -20.0
DDAH2 dimethylarginine dimethylaminohydrolase 2 -20.0
PSRC1 proline/serine-rich coiled-coil 1 -20.0
MAST1 microtubule associated serine/threonine kinase 1 -20.0
ASNS asparagine synthetase (glutamine-hydrolyzing) -20.0
UXT ubiquitously-expressed, prefoldin-like chaperone -20.0
LGALS1 lectin, galactoside-binding, soluble, 1 -20.0
CYSTM1 cysteine-rich transmembrane module containing 1 -20.0
MSI1 musashi RNA-binding protein 1 -20.0
ZNF692 zinc finger protein 692 -20.0
PCGF1 polycomb group ring finger 1 -20.0
TMSB15A thymosin beta 15a -20.0
DLG4 discs, large homolog 4 (Drosophila) -20.0
CCDC167 coiled-coil domain containing 167 -20.0
ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E -20.0
LIG3 ligase III, DNA, ATP-dependent -20.0
CSAD cysteine sulfinic acid decarboxylase -20.0
ANKRD37 ankyrin repeat domain 37 -20.0
FADS3 fatty acid desaturase 3 -20.0
MAN2B1 mannosidase, alpha, class 2B, member 1 -20.0
MED30 mediator complex subunit 30 -20.0
MXD3 MAX dimerization protein 3 -20.0
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -20.0
TRPM4 transient receptor potential cation channel, subfamily M, member 4 -20.0
DTNB dystrobrevin, beta -20.0