| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KI perturbation targeting KMT2C in HEK293T cell line (Study accession: SRP108473) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_7291_KI_KMT2C_SRP108473 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CCDC78 | coiled-coil domain containing 78 | 20.0 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 20.0 |
| TCP11L1 | t-complex 11, testis-specific-like 1 | 20.0 |
| CIRBP | cold inducible RNA binding protein | 20.0 |
| NOXO1 | NADPH oxidase organizer 1 | 19.699 |
| MROH1 | maestro heat-like repeat family member 1 | 18.284 |
| ERCC1 | excision repair cross-complementation group 1 | 15.4194 |
| HIST1H4I | histone cluster 1, H4i | 15.3495 |
| TCP1 | t-complex 1 | 14.6998 |
| CPSF3L | cleavage and polyadenylation specific factor 3-like | 13.6634 |
| MST1 | macrophage stimulating 1 | 13.6048 |
| SFT2D3 | SFT2 domain containing 3 | 11.7938 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 | 11.2077 |
| MAMDC4 | MAM domain containing 4 | 11.0126 |
| MFSD11 | major facilitator superfamily domain containing 11 | 10.5227 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 10.167 |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 | 8.97583 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | 8.96167 |
| CLN5 | ceroid-lipofuscinosis, neuronal 5 | 8.03307 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 7.84982 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 7.03529 |
| RNF24 | ring finger protein 24 | 7.01908 |
| METRN | meteorin, glial cell differentiation regulator | 6.84514 |
| SARM1 | sterile alpha and TIR motif containing 1 | 6.8042 |
| FN1 | fibronectin 1 | 6.64877 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 6.47956 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | 6.36526 |
| PLCH2 | phospholipase C, eta 2 | 6.30689 |
| SLC46A1 | solute carrier family 46 (folate transporter), member 1 | 6.18797 |
| DARS2 | aspartyl-tRNA synthetase 2, mitochondrial | 5.93961 |
| CD151 | CD151 molecule (Raph blood group) | 5.889 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 5.83768 |
| TMED1 | transmembrane emp24 protein transport domain containing 1 | 5.83382 |
| SLC7A10 | solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 | 5.69391 |
| CENPP | centromere protein P | 5.67803 |
| NIT2 | nitrilase family, member 2 | 5.63784 |
| CREB3L4 | cAMP responsive element binding protein 3-like 4 | 5.44914 |
| SWI5 | SWI5 recombination repair homolog (yeast) | 5.30353 |
| C5ORF45 | chromosome 5 open reading frame 45 | 4.99234 |
| USP20 | ubiquitin specific peptidase 20 | 4.92575 |
| DXO | decapping exoribonuclease | 4.8458 |
| WDR24 | WD repeat domain 24 | 4.8423 |
| SRRM2 | serine/arginine repetitive matrix 2 | 4.687 |
| VPRBP | Vpr (HIV-1) binding protein | 4.671 |
| STX17 | syntaxin 17 | 4.61766 |
| SLC7A6OS | solute carrier family 7, member 6 opposite strand | 4.55125 |
| CIDEB | cell death-inducing DFFA-like effector b | 4.55125 |
| NPB | neuropeptide B | 4.55049 |
| ASIC3 | acid sensing (proton gated) ion channel 3 | 4.55049 |
| EML5 | echinoderm microtubule associated protein like 5 | 4.45817 |
| PTOV1 | prostate tumor overexpressed 1 | 4.34748 |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) | 4.27442 |
| CALHM2 | calcium homeostasis modulator 2 | 4.18999 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) | 4.17658 |
| MYO19 | myosin XIX | 4.08361 |
| SPNS2 | spinster homolog 2 (Drosophila) | 4.04785 |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G | 4.03112 |
| TSSK2 | testis-specific serine kinase 2 | 4.03025 |
| CDIP1 | cell death-inducing p53 target 1 | 3.88186 |
| RABL6 | RAB, member RAS oncogene family-like 6 | 3.82071 |
| SURF4 | surfeit 4 | 3.81229 |
| RYR3 | ryanodine receptor 3 | 3.80432 |
| C16ORF93 | chromosome 16 open reading frame 93 | 3.79362 |
| VPS9D1 | VPS9 domain containing 1 | 3.67878 |
| DENND4C | DENN/MADD domain containing 4C | 3.66163 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing | 3.65218 |
| CDT1 | chromatin licensing and DNA replication factor 1 | 3.50034 |
| SRRT | serrate, RNA effector molecule | 3.4966 |
| ZNF839 | zinc finger protein 839 | 3.45956 |
| HMHA1 | histocompatibility (minor) HA-1 | 3.42317 |
| GGCX | gamma-glutamyl carboxylase | 3.42093 |
| GLIS2 | GLIS family zinc finger 2 | 3.41296 |
| CORO1B | coronin, actin binding protein, 1B | 3.35785 |
| C16ORF59 | chromosome 16 open reading frame 59 | 3.3058 |
| C9ORF16 | chromosome 9 open reading frame 16 | 3.25228 |
| UBXN6 | UBX domain protein 6 | 3.23895 |
| PHYKPL | 5-phosphohydroxy-L-lysine phospho-lyase | 3.22214 |
| CPLX2 | complexin 2 | 3.2069 |
| NAV1 | neuron navigator 1 | 3.16133 |
| ZNF593OS | ZNF593 opposite strand | 3.10696 |
| ANAPC11 | anaphase promoting complex subunit 11 | 3.0898 |
| BRD3 | bromodomain containing 3 | 3.04846 |
| SZT2 | seizure threshold 2 homolog (mouse) | 3.03137 |
| PLLP | plasmolipin | 3.01658 |
| LRTOMT | leucine rich transmembrane and O-methyltransferase domain containing | 3.01515 |
| SLC25A25 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 | 3.00712 |
| KAT5 | K(lysine) acetyltransferase 5 | 2.99525 |
| CYB561D2 | cytochrome b561 family, member D2 | 2.92495 |
| CALR | calreticulin | 2.91586 |
| ILK | integrin-linked kinase | 2.86515 |
| ZBTB17 | zinc finger and BTB domain containing 17 | 2.84786 |
| E4F1 | E4F transcription factor 1 | 2.84661 |
| ASB6 | ankyrin repeat and SOCS box containing 6 | 2.83034 |
| ARL10 | ADP-ribosylation factor-like 10 | 2.82824 |
| IFT20 | intraflagellar transport 20 | 2.81291 |
| IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | 2.80337 |
| SNAP47 | synaptosomal-associated protein, 47kDa | 2.80221 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase | 2.7814 |
| FAM166A | family with sequence similarity 166, member A | 2.76803 |
| ST5 | suppression of tumorigenicity 5 | 2.7587 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCDC152 | coiled-coil domain containing 152 | -20.0 |
| H1F0 | H1 histone family, member 0 | -20.0 |
| NECAB1 | N-terminal EF-hand calcium binding protein 1 | -18.8239 |
| UFSP2 | UFM1-specific peptidase 2 | -16.5262 |
| TBPL1 | TBP-like 1 | -15.8951 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | -15.6968 |
| FAM92A1 | family with sequence similarity 92, member A1 | -13.834 |
| LOC122455342 | testis-specific serine/proline-rich protein | -12.2791 |
| MRPS18C | mitochondrial ribosomal protein S18C | -11.6997 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -10.6793 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -10.6066 |
| JMJD4 | jumonji domain containing 4 | -10.3353 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 | -9.84389 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -9.31948 |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) | -8.81746 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | -8.79938 |
| VPS37A | vacuolar protein sorting 37 homolog A (S. cerevisiae) | -8.32969 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 | -8.16014 |
| LDLRAD2 | low density lipoprotein receptor class A domain containing 2 | -7.94137 |
| C14ORF166 | chromosome 14 open reading frame 166 | -7.71314 |
| CHM | choroideremia (Rab escort protein 1) | -7.41509 |
| BRD7 | bromodomain containing 7 | -6.9128 |
| UFD1L | ubiquitin fusion degradation 1 like (yeast) | -6.90767 |
| RGS17 | regulator of G-protein signaling 17 | -6.86755 |
| TEX9 | testis expressed 9 | -6.79588 |
| KBTBD7 | kelch repeat and BTB (POZ) domain containing 7 | -6.77311 |
| EML2 | echinoderm microtubule associated protein like 2 | -6.18797 |
| RNF169 | ring finger protein 169 | -6.11208 |
| MARCH7 | membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase | -6.08548 |
| GPR39 | G protein-coupled receptor 39 | -5.91566 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 | -5.91232 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -5.85758 |
| FMNL3 | formin-like 3 | -5.82704 |
| BID | BH3 interacting domain death agonist | -5.69925 |
| CABP7 | calcium binding protein 7 | -5.68533 |
| NCAPG | non-SMC condensin I complex, subunit G | -5.63431 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | -5.58646 |
| FSIP2 | fibrous sheath interacting protein 2 | -5.44525 |
| SPATA1 | spermatogenesis associated 1 | -5.34539 |
| PRSS23 | protease, serine, 23 | -5.30324 |
| TRIM52 | tripartite motif containing 52 | -5.20688 |
| PCGF3 | polycomb group ring finger 3 | -5.18913 |
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | -5.16747 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -4.92894 |
| COG5 | component of oligomeric golgi complex 5 | -4.92521 |
| PHKG1 | phosphorylase kinase, gamma 1 (muscle) | -4.65416 |
| TSPAN11 | tetraspanin 11 | -4.61672 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -4.6036 |
| USP45 | ubiquitin specific peptidase 45 | -4.58273 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -4.52656 |
| GYG1 | glycogenin 1 | -4.30572 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | -4.27442 |
| LMNTD2 | lamin tail domain containing 2 | -4.21361 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -4.15593 |
| FCHSD1 | FCH and double SH3 domains 1 | -4.12395 |
| SBF2 | SET binding factor 2 | -4.10586 |
| DDTL | D-dopachrome tautomerase-like | -4.10397 |
| DNAH10 | dynein, axonemal, heavy chain 10 | -3.89372 |
| COX20 | COX20 cytochrome c oxidase assembly factor | -3.84958 |
| ABI2 | abl-interactor 2 | -3.80095 |
| RINT1 | RAD50 interactor 1 | -3.7475 |
| METTL20 | methyltransferase like 20 | -3.74085 |
| CCNH | cyclin H | -3.73335 |
| ELP2 | elongator acetyltransferase complex subunit 2 | -3.72213 |
| C22ORF23 | chromosome 22 open reading frame 23 | -3.71627 |
| RBBP4 | retinoblastoma binding protein 4 | -3.71627 |
| HIST1H1E | histone cluster 1, H1e | -3.70314 |
| B9D1 | B9 protein domain 1 | -3.67878 |
| MTRF1L | mitochondrial translational release factor 1-like | -3.64818 |
| SPAG4 | sperm associated antigen 4 | -3.53531 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -3.53531 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | -3.49363 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | -3.48268 |
| MTERF4 | mitochondrial transcription termination factor 4 | -3.45946 |
| ZNF575 | zinc finger protein 575 | -3.45434 |
| TSC22D3 | TSC22 domain family, member 3 | -3.45163 |
| PITPNA | phosphatidylinositol transfer protein, alpha | -3.41296 |
| LRRC75A | leucine rich repeat containing 75A | -3.41296 |
| CDC42SE1 | CDC42 small effector 1 | -3.38561 |
| ATM | ATM serine/threonine kinase | -3.3808 |
| ZNF710 | zinc finger protein 710 | -3.3808 |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 | -3.37415 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -3.36177 |
| SPRYD4 | SPRY domain containing 4 | -3.36117 |
| TFIP11 | tuftelin interacting protein 11 | -3.28801 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) | -3.28473 |
| CCDC159 | coiled-coil domain containing 159 | -3.26843 |
| UTP23 | UTP23, small subunit (SSU) processome component, homolog (yeast) | -3.24942 |
| C22ORF15 | chromosome 22 open reading frame 15 | -3.19012 |
| C19ORF54 | chromosome 19 open reading frame 54 | -3.17131 |
| FOXH1 | forkhead box H1 | -3.17131 |
| C1ORF112 | chromosome 1 open reading frame 112 | -3.10832 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -3.0635 |
| COL6A2 | collagen, type VI, alpha 2 | -3.04443 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -3.00041 |
| ASPHD2 | aspartate beta-hydroxylase domain containing 2 | -2.95318 |
| RHOQ | ras homolog family member Q | -2.91093 |
| FBXO22 | F-box protein 22 | -2.90022 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -2.89432 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -2.8826 |
