Perturb_7336_KD_SUGP1_SRP286876 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting SUGP1 in HEK293T cell line (Study accession: SRP286876) (PerturbAtlas)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Perturb_7336_KD_SUGP1_SRP286876 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
MYO15B myosin XVB 20.0
ARRDC1 arrestin domain containing 1 20.0
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 17.3382
TSPAN4 tetraspanin 4 17.2916
DDR2 discoidin domain receptor tyrosine kinase 2 16.3558
SGPP2 sphingosine-1-phosphate phosphatase 2 15.8147
PKDREJ polycystin (PKD) family receptor for egg jelly 14.8201
WFS1 Wolfram syndrome 1 (wolframin) 14.3971
H1F0 H1 histone family, member 0 14.298
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 13.4502
LRRC75A leucine rich repeat containing 75A 13.1383
CARHSP1 calcium regulated heat stable protein 1, 24kDa 12.5722
CHM choroideremia (Rab escort protein 1) 12.1584
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 11.457
LPCAT3 lysophosphatidylcholine acyltransferase 3 10.9182
LIMD1 LIM domains containing 1 10.8371
TMOD1 tropomodulin 1 10.663
FAM69B family with sequence similarity 69, member B 10.4552
GLIS2 GLIS family zinc finger 2 9.95149
NID2 nidogen 2 (osteonidogen) 9.51168
GANC glucosidase, alpha; neutral C 9.43528
NOXO1 NADPH oxidase organizer 1 9.41722
ZNF263 zinc finger protein 263 9.19533
CCDC64 coiled-coil domain containing 64 8.69554
PDZD2 PDZ domain containing 2 8.60822
CTC1 CTS telomere maintenance complex component 1 8.55257
MMP24-AS1 MMP24 antisense RNA 1 8.35067
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 8.26351
TBX10 T-box 10 8.25898
LOC122455342 testis-specific serine/proline-rich protein 8.07567
TSSK2 testis-specific serine kinase 2 8.06231
STK17A serine/threonine kinase 17a 8.01054
DGKQ diacylglycerol kinase, theta 110kDa 8.00534
VIL1 villin 1 7.85688
CC2D2B coiled-coil and C2 domain containing 2B 7.71948
GNG13 guanine nucleotide binding protein (G protein), gamma 13 7.51607
PARD6G par-6 family cell polarity regulator gamma 7.35329
EIF3G eukaryotic translation initiation factor 3, subunit G 7.32356
STC2 stanniocalcin 2 7.26201
PLCH2 phospholipase C, eta 2 7.24721
RECQL RecQ helicase-like 7.22451
RAB6B RAB6B, member RAS oncogene family 7.02769
CAPN2 calpain 2, (m/II) large subunit 6.9297
RUFY2 RUN and FYVE domain containing 2 6.75465
PHF10 PHD finger protein 10 6.58501
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 6.5232
PLCD4 phospholipase C, delta 4 6.46132
CCDC78 coiled-coil domain containing 78 6.2543
SLC22A23 solute carrier family 22, member 23 6.19875
LONP2 lon peptidase 2, peroxisomal 6.1986
CDC25C cell division cycle 25C 6.18049
HYI hydroxypyruvate isomerase (putative) 6.18049
BBIP1 BBSome interacting protein 1 6.12431
NCOR1 nuclear receptor corepressor 1 6.09717
DCAF13 DDB1 and CUL4 associated factor 13 6.03309
EPB41L4A erythrocyte membrane protein band 4.1 like 4A 5.93912
TCHP trichoplein, keratin filament binding 5.75565
OBSL1 obscurin-like 1 5.75565
SH3D19 SH3 domain containing 19 5.66372
AVIL advillin 5.66082
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 5.64093
SARM1 sterile alpha and TIR motif containing 1 5.52622
LONP1 lon peptidase 1, mitochondrial 5.3808
CPSF4L cleavage and polyadenylation specific factor 4-like 5.29863
ZC3HAV1L zinc finger CCCH-type, antiviral 1-like 5.21325
RPL15 ribosomal protein L15 5.18421
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 5.17437
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 5.17437
HERPUD2 HERPUD family member 2 5.1628
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 5.13797
PHPT1 phosphohistidine phosphatase 1 5.07235
BTBD2 BTB (POZ) domain containing 2 5.05826
NR2C2 nuclear receptor subfamily 2, group C, member 2 5.03155
LGALS8 lectin, galactoside-binding, soluble, 8 5.00431
PITPNA phosphatidylinositol transfer protein, alpha 4.99376
SRRM2 serine/arginine repetitive matrix 2 4.89964
KIF2A kinesin heavy chain member 2A 4.84868
PROX2 prospero homeobox 2 4.79702
GAS2 growth arrest-specific 2 4.75233
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 4.74111
RB1CC1 RB1-inducible coiled-coil 1 4.70413
DXO decapping exoribonuclease 4.63348
PDPK1 3-phosphoinositide dependent protein kinase 1 4.58768
WDR33 WD repeat domain 33 4.5685
RHOB ras homolog family member B 4.5331
ATG10 autophagy related 10 4.5331
VPS13B vacuolar protein sorting 13 homolog B (yeast) 4.5265
GLOD4 glyoxalase domain containing 4 4.45375
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 4.43897
SRR serine racemase 4.42022
CCDC73 coiled-coil domain containing 73 4.39895
LOC100288842 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 pseudogene 4.37541
QRFP pyroglutamylated RFamide peptide 4.36288
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 4.32967
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 4.26448
ACO2 aconitase 2, mitochondrial 4.25461
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 4.23702
DAGLB diacylglycerol lipase, beta 4.18545
MCM3AP minichromosome maintenance complex component 3 associated protein 4.18256
RBPMS RNA binding protein with multiple splicing 4.13789

decreased expression

Symbol Name Standardized Value
C12ORF73 chromosome 12 open reading frame 73 -20.0
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -16.6706
ERAP1 endoplasmic reticulum aminopeptidase 1 -16.5558
METTL5 methyltransferase like 5 -16.0891
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -15.5826
TEX2 testis expressed 2 -15.5037
FMNL1 formin-like 1 -15.2899
LMNTD2 lamin tail domain containing 2 -14.9117
LDLRAD2 low density lipoprotein receptor class A domain containing 2 -12.6147
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C -12.5194
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -12.0787
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -10.2303
C14ORF166 chromosome 14 open reading frame 166 -10.0916
FADS1 fatty acid desaturase 1 -9.99288
NUP88 nucleoporin 88kDa -9.83487
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -9.56007
NCAPG non-SMC condensin I complex, subunit G -8.69924
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -8.24617
SLC19A1 solute carrier family 19 (folate transporter), member 1 -7.75033
FAR2 fatty acyl CoA reductase 2 -7.74573
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -7.13045
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) -7.00742
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -6.75465
PHKG2 phosphorylase kinase, gamma 2 (testis) -6.57219
JMJD4 jumonji domain containing 4 -6.54359
ZC3H14 zinc finger CCCH-type containing 14 -6.46132
PRPF39 pre-mRNA processing factor 39 -6.44483
CLVS1 clavesin 1 -6.41828
SRPX2 sushi-repeat containing protein, X-linked 2 -6.33884
ZNF710 zinc finger protein 710 -6.31092
YBX1 Y box binding protein 1 -6.28334
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -6.20088
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13 -6.18411
MROH8 maestro heat-like repeat family member 8 -6.18411
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -6.17806
IQCC IQ motif containing C -6.1542
TRUB2 TruB pseudouridine (psi) synthase family member 2 -6.14232
PPP1R12B protein phosphatase 1, regulatory subunit 12B -6.12431
PMPCB peptidase (mitochondrial processing) beta -6.09717
CDC14B cell division cycle 14B -5.98051
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -5.9461
C12ORF29 chromosome 12 open reading frame 29 -5.85521
LUC7L3 LUC7-like 3 (S. cerevisiae) -5.84055
USP50 ubiquitin specific peptidase 50 -5.82514
FOXH1 forkhead box H1 -5.76048
BTG3 BTG family, member 3 -5.66377
PNKP polynucleotide kinase 3'-phosphatase -5.59524
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -5.54641
HMGN5 high mobility group nucleosome binding domain 5 -5.45316
FAT2 FAT atypical cadherin 2 -5.40056
LINC00094 long intergenic non-protein coding RNA 94 -5.31049
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -5.2581
NDEL1 nudE neurodevelopment protein 1-like 1 -5.00609
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 -4.95201
COX11 COX11 cytochrome c oxidase copper chaperone -4.90413
LOC338667 V-set and immunoglobulin domain-containing protein 10-like -4.80911
LCORL ligand dependent nuclear receptor corepressor-like -4.67688
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase -4.56496
TUBGCP2 tubulin, gamma complex associated protein 2 -4.43038
COX20 COX20 cytochrome c oxidase assembly factor -4.28449
TUBA1C tubulin, alpha 1c -4.23005
NASP nuclear autoantigenic sperm protein (histone-binding) -4.14283
ICAM2 intercellular adhesion molecule 2 -4.12092
EPN3 epsin 3 -4.02265
MED16 mediator complex subunit 16 -3.98471
TMCO4 transmembrane and coiled-coil domains 4 -3.97884
RFC5 replication factor C (activator 1) 5, 36.5kDa -3.97709
EIF5B eukaryotic translation initiation factor 5B -3.96728
RBM25 RNA binding motif protein 25 -3.94572
PTMS parathymosin -3.94572
RANGRF RAN guanine nucleotide release factor -3.91368
LECT2 leukocyte cell-derived chemotaxin 2 -3.91305
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 -3.82589
SZT2 seizure threshold 2 homolog (mouse) -3.71635
BOP1 block of proliferation 1 -3.71348
DLD dihydrolipoamide dehydrogenase -3.7036
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -3.63746
SNX22 sorting nexin 22 -3.61057
LRRC7 leucine rich repeat containing 7 -3.58967
FAM166A family with sequence similarity 166, member A -3.51739
SLC9B1 solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1 -3.49697
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 -3.49539
TSACC TSSK6 activating co-chaperone -3.48498
CHAD chondroadherin -3.48433
CA14 carbonic anhydrase XIV -3.48433
ACOT13 acyl-CoA thioesterase 13 -3.47531
NEB nebulin -3.46264
CALR calreticulin -3.44256
DCDC2B doublecortin domain containing 2B -3.38643
CCNA2 cyclin A2 -3.38121
SCD stearoyl-CoA desaturase (delta-9-desaturase) -3.3712
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -3.36748
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion -3.36543
MARVELD3 MARVEL domain containing 3 -3.33293
TBRG1 transforming growth factor beta regulator 1 -3.29971
ANKRD34A ankyrin repeat domain 34A -3.25267
HDGFRP3 hepatoma-derived growth factor, related protein 3 -3.2355
FRS3 fibroblast growth factor receptor substrate 3 -3.1828
PCOLCE procollagen C-endopeptidase enhancer -3.14456
LRTOMT leucine rich transmembrane and O-methyltransferase domain containing -3.09244