Perturb_7486_OE_Mir668_SRP155560 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description OE perturbation targeting Mir668 in HEK293T cell line (Study accession: SRP155560) (PerturbAtlas)
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Genes

200 genes differentially expressed following the Perturb_7486_OE_Mir668_SRP155560 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
UHMK1 U2AF homology motif (UHM) kinase 1 13.132
PFKL phosphofructokinase, liver 12.1479
ONECUT2 one cut homeobox 2 9.8733
ZNF711 zinc finger protein 711 8.77911
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 8.4449
FKBP4 FK506 binding protein 4, 59kDa 7.95222
HIPK1 homeodomain interacting protein kinase 1 7.5386
TTYH3 tweety family member 3 6.64917
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 6.44814
ELAVL2 ELAV like neuron-specific RNA binding protein 2 6.24222
SFMBT1 Scm-like with four mbt domains 1 5.66081
TOMM34 translocase of outer mitochondrial membrane 34 5.64948
NSF N-ethylmaleimide-sensitive factor 5.47232
RRAS2 related RAS viral (r-ras) oncogene homolog 2 5.32086
SOCS6 suppressor of cytokine signaling 6 4.97529
CBX2 chromobox homolog 2 4.81436
NAE1 NEDD8 activating enzyme E1 subunit 1 4.38462
RPA1 replication protein A1, 70kDa 4.08519
VDAC1 voltage-dependent anion channel 1 4.03856
POLRMT polymerase (RNA) mitochondrial (DNA directed) 3.93528
RACGAP1 Rac GTPase activating protein 1 3.80144
NRARP NOTCH-regulated ankyrin repeat protein 3.7593
EPCAM epithelial cell adhesion molecule 3.7593
RCC2 regulator of chromosome condensation 2 3.75908
MFSD3 major facilitator superfamily domain containing 3 3.70254
SRM spermidine synthase 3.69052
RC3H2 ring finger and CCCH-type domains 2 3.64939
G6PC3 glucose 6 phosphatase, catalytic, 3 3.63669
MXRA8 matrix-remodelling associated 8 3.63425
TCOF1 Treacher Collins-Franceschetti syndrome 1 3.62498
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 3.58871
SRRM2 serine/arginine repetitive matrix 2 3.58021
CAPNS1 calpain, small subunit 1 3.55097
SH3GLB2 SH3-domain GRB2-like endophilin B2 3.43594
FAM210B family with sequence similarity 210, member B 3.42647
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 3.41146
MRPS28 mitochondrial ribosomal protein S28 3.31813
ZNF121 zinc finger protein 121 3.31592
SESN3 sestrin 3 3.28433
SREK1IP1 SREK1-interacting protein 1 3.263
RAB11FIP5 RAB11 family interacting protein 5 (class I) 3.263
CNBP CCHC-type zinc finger, nucleic acid binding protein 3.263
DDRGK1 DDRGK domain containing 1 3.25285
DVL3 dishevelled segment polarity protein 3 3.19391
ETF1 eukaryotic translation termination factor 1 3.12754
LTBP1 latent transforming growth factor beta binding protein 1 3.11983
RPA2 replication protein A2, 32kDa 3.10637
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 3.09626
ULK1 unc-51 like autophagy activating kinase 1 3.03571
CA2 carbonic anhydrase II 3.03571
SLC41A3 solute carrier family 41, member 3 3.01272
SNX17 sorting nexin 17 2.92746
TTLL12 tubulin tyrosine ligase-like family member 12 2.90031
AK4 adenylate kinase 4 2.88393
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 2.87225
PIAS3 protein inhibitor of activated STAT, 3 2.85998
NPDC1 neural proliferation, differentiation and control, 1 2.79217
ARL2 ADP-ribosylation factor-like 2 2.76917
MAPK12 mitogen-activated protein kinase 12 2.69981
LONRF2 LON peptidase N-terminal domain and ring finger 2 2.68445
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 2.68222
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 2.68222
HES4 hes family bHLH transcription factor 4 2.66449
CBX6 chromobox homolog 6 2.66443
FGFR3 fibroblast growth factor receptor 3 2.65048
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) 2.61448
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 2.61312
FASTK Fas-activated serine/threonine kinase 2.6072
HSPA8 heat shock 70kDa protein 8 2.60337
C1QTNF6 C1q and tumor necrosis factor related protein 6 2.58431
LMAN2L lectin, mannose-binding 2-like 2.56312
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 2.53506
INO80E INO80 complex subunit E 2.52526
MAVS mitochondrial antiviral signaling protein 2.51178
RNPS1 RNA binding protein S1, serine-rich domain 2.49658
ZCCHC12 zinc finger, CCHC domain containing 12 2.48553
JRK Jrk homolog (mouse) 2.46792
PTGES2 prostaglandin E synthase 2 2.46687
NPM3 nucleophosmin/nucleoplasmin 3 2.46212
METRN meteorin, glial cell differentiation regulator 2.37986
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 2.37148
ZNF587B zinc finger protein 587B 2.28304
MCM7 minichromosome maintenance complex component 7 2.26695
TRIM23 tripartite motif containing 23 2.26671
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 2.13954
S1PR2 sphingosine-1-phosphate receptor 2 2.13954
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 2.10652
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 2.07963
UBB ubiquitin B 2.07186
ACADSB acyl-CoA dehydrogenase, short/branched chain 2.0634
KIFC2 kinesin family member C2 2.06307
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 2.05085
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) 2.03477
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 2.03477
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 2.02275
NRBP1 nuclear receptor binding protein 1 2.00246
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 1.9552
MDC1 mediator of DNA-damage checkpoint 1 1.9552
LGMN legumain 1.9507
SSH1 slingshot protein phosphatase 1 1.9507

decreased expression

Symbol Name Standardized Value
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -20.0
GOLM1 golgi membrane protein 1 -20.0
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 -20.0
PRDX3 peroxiredoxin 3 -18.9208
RPS27A ribosomal protein S27a -13.132
H3F3A H3 histone, family 3A -12.2719
MOXD1 monooxygenase, DBH-like 1 -11.2205
ERP29 endoplasmic reticulum protein 29 -9.75019
BTBD3 BTB (POZ) domain containing 3 -9.46815
LIFR leukemia inhibitory factor receptor alpha -9.1843
COLGALT1 collagen beta(1-O)galactosyltransferase 1 -8.99104
PALM2-AKAP2 PALM2-AKAP2 readthrough -8.81526
GLOD4 glyoxalase domain containing 4 -8.77911
RPS4X ribosomal protein S4, X-linked -8.21007
RPL36 ribosomal protein L36 -8.12571
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -8.02795
BCL7B B-cell CLL/lymphoma 7B -7.96696
MED1 mediator complex subunit 1 -7.93763
LMAN2 lectin, mannose-binding 2 -7.85314
BASP1 brain abundant, membrane attached signal protein 1 -7.85314
SKAP2 src kinase associated phosphoprotein 2 -7.81498
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog -7.74328
PM20D2 peptidase M20 domain containing 2 -7.3274
GCC1 GRIP and coiled-coil domain containing 1 -7.25113
TMTC3 transmembrane and tetratricopeptide repeat containing 3 -7.22026
DENND6A DENN/MADD domain containing 6A -6.81529
TSPYL1 TSPY-like 1 -6.69217
TMOD3 tropomodulin 3 (ubiquitous) -6.61703
GOLIM4 golgi integral membrane protein 4 -6.59943
U2AF2 U2 small nuclear RNA auxiliary factor 2 -6.59943
STK36 serine/threonine kinase 36 -6.37858
SHCBP1 SHC SH2-domain binding protein 1 -6.18942
ADAM10 ADAM metallopeptidase domain 10 -6.0774
WLS wntless Wnt ligand secretion mediator -6.00697
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 -5.94805
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -5.91131
TPD52 tumor protein D52 -5.83687
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -5.67106
KCTD10 potassium channel tetramerization domain containing 10 -5.56588
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -5.54219
PIGO phosphatidylinositol glycan anchor biosynthesis, class O -5.21457
SLC37A3 solute carrier family 37, member 3 -5.20827
IPO7 importin 7 -5.20827
ADGRL2 adhesion G protein-coupled receptor L2 -5.03975
TMEM2 transmembrane protein 2 -4.97448
TGOLN2 trans-golgi network protein 2 -4.90586
EPHA7 EPH receptor A7 -4.81352
TMEM194A transmembrane protein 194A -4.74247
PEX2 peroxisomal biogenesis factor 2 -4.70848
CCDC124 coiled-coil domain containing 124 -4.70848
GMCL1 germ cell-less, spermatogenesis associated 1 -4.69794
TSPAN5 tetraspanin 5 -4.69794
MAF1 MAF1 homolog (S. cerevisiae) -4.63958
VCAN versican -4.55118
ICE1 interactor of little elongation complex ELL subunit 1 -4.52988
USP22 ubiquitin specific peptidase 22 -4.51376
EFR3A EFR3 homolog A (S. cerevisiae) -4.48903
KIF3B kinesin family member 3B -4.46289
SLC39A9 solute carrier family 39, member 9 -4.43346
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -4.40678
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -4.40678
PGAM1 phosphoglycerate mutase 1 (brain) -4.3628
STAU1 staufen double-stranded RNA binding protein 1 -4.14754
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -4.10317
IFT27 intraflagellar transport 27 -4.09559
FAM107B family with sequence similarity 107, member B -4.07608
TGFBR1 transforming growth factor, beta receptor 1 -4.01557
TAGLN2 transgelin 2 -3.99611
SSFA2 sperm specific antigen 2 -3.97654
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) -3.90728
APRT adenine phosphoribosyltransferase -3.90224
BBX bobby sox homolog (Drosophila) -3.88067
HHAT hedgehog acyltransferase -3.87542
MIB1 mindbomb E3 ubiquitin protein ligase 1 -3.84521
KLHL12 kelch-like family member 12 -3.79572
PSKH1 protein serine kinase H1 -3.7593
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33 -3.7593
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -3.75908
RNASEH1 ribonuclease H1 -3.7514
PON2 paraoxonase 2 -3.71829
CD109 CD109 molecule -3.71829
DCXR dicarbonyl/L-xylulose reductase -3.71071
MAST2 microtubule associated serine/threonine kinase 2 -3.69052
HNRNPF heterogeneous nuclear ribonucleoprotein F -3.66029
RRBP1 ribosome binding protein 1 -3.64788
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 -3.64421
ILF2 interleukin enhancer binding factor 2 -3.63669
YES1 YES proto-oncogene 1, Src family tyrosine kinase -3.63425
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -3.63425
TMEM160 transmembrane protein 160 -3.62498
WDR82 WD repeat domain 82 -3.52407
RPL22 ribosomal protein L22 -3.50248
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase -3.44817
H2AFY2 H2A histone family, member Y2 -3.42647
HMGA2 high mobility group AT-hook 2 -3.40887
RPS5 ribosomal protein S5 -3.40453
SRP9 signal recognition particle 9kDa -3.38933
PDE3B phosphodiesterase 3B, cGMP-inhibited -3.37107
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats -3.30939
M6PR mannose-6-phosphate receptor (cation dependent) -3.29959