| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting DICER1 in HEK293T cell line (Study accession: SRP186271) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_7494_KD_DICER1_SRP186271 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MPPE1 | metallophosphoesterase 1 | 20.0 |
| ORAOV1 | oral cancer overexpressed 1 | 20.0 |
| SPRYD4 | SPRY domain containing 4 | 20.0 |
| ZNF235 | zinc finger protein 235 | 20.0 |
| CCDC152 | coiled-coil domain containing 152 | 20.0 |
| KRT8 | keratin 8, type II | 20.0 |
| OGG1 | 8-oxoguanine DNA glycosylase | 20.0 |
| TUBB6 | tubulin, beta 6 class V | 18.9586 |
| SLC35E2B | solute carrier family 35, member E2B | 18.5528 |
| HIST1H4I | histone cluster 1, H4i | 18.2518 |
| ZNF135 | zinc finger protein 135 | 17.9318 |
| CERKL | ceramide kinase-like | 17.2161 |
| CDC42SE1 | CDC42 small effector 1 | 16.0299 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 15.0535 |
| CENPO | centromere protein O | 14.8738 |
| ZNF224 | zinc finger protein 224 | 13.9395 |
| FAM166A | family with sequence similarity 166, member A | 13.737 |
| JMJD8 | jumonji domain containing 8 | 12.2144 |
| PTER | phosphotriesterase related | 12.191 |
| PHF10 | PHD finger protein 10 | 12.1615 |
| ENOSF1 | enolase superfamily member 1 | 11.7613 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 11.521 |
| WDR33 | WD repeat domain 33 | 11.4383 |
| CGREF1 | cell growth regulator with EF-hand domain 1 | 11.3192 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit | 11.0262 |
| IL17D | interleukin 17D | 11.0044 |
| ACBD6 | acyl-CoA binding domain containing 6 | 10.5837 |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) | 10.5063 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 10.3234 |
| CCDC159 | coiled-coil domain containing 159 | 10.2642 |
| GPR39 | G protein-coupled receptor 39 | 9.99627 |
| EMG1 | EMG1 N1-specific pseudouridine methyltransferase | 9.41261 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 9.10486 |
| PSMG2 | proteasome (prosome, macropain) assembly chaperone 2 | 8.74316 |
| SARM1 | sterile alpha and TIR motif containing 1 | 8.73762 |
| C1ORF86 | chromosome 1 open reading frame 86 | 8.34054 |
| LYRM2 | LYR motif containing 2 | 8.0463 |
| DENND2A | DENN/MADD domain containing 2A | 7.76522 |
| SBF2 | SET binding factor 2 | 7.62227 |
| GCC1 | GRIP and coiled-coil domain containing 1 | 7.52553 |
| NEFL | neurofilament, light polypeptide | 7.38092 |
| FMNL3 | formin-like 3 | 7.36798 |
| KCP | kielin/chordin-like protein | 7.32967 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 | 7.27675 |
| VTI1B | vesicle transport through interaction with t-SNAREs 1B | 7.26051 |
| HOXA10 | homeobox A10 | 7.12072 |
| DLD | dihydrolipoamide dehydrogenase | 6.93297 |
| VPS37A | vacuolar protein sorting 37 homolog A (S. cerevisiae) | 6.89101 |
| LRRC75A | leucine rich repeat containing 75A | 6.85791 |
| POLG | polymerase (DNA directed), gamma | 6.45456 |
| ENO3 | enolase 3 (beta, muscle) | 6.44312 |
| GJD3 | gap junction protein, delta 3, 31.9kDa | 6.33143 |
| LECT2 | leukocyte cell-derived chemotaxin 2 | 6.32576 |
| ATP5S | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) | 6.24414 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | 6.19636 |
| RAPSN | receptor-associated protein of the synapse | 6.10765 |
| HEATR1 | HEAT repeat containing 1 | 6.10764 |
| BRI3 | brain protein I3 | 5.79498 |
| EMC9 | ER membrane protein complex subunit 9 | 5.64459 |
| SLC24A5 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 | 5.61716 |
| C10ORF95 | chromosome 10 open reading frame 95 | 5.48886 |
| RER1 | retention in endoplasmic reticulum sorting receptor 1 | 5.1686 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 5.16799 |
| IFT22 | intraflagellar transport 22 | 5.15543 |
| FAM69B | family with sequence similarity 69, member B | 5.1281 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 5.1281 |
| COG5 | component of oligomeric golgi complex 5 | 5.03847 |
| PHYHIPL | phytanoyl-CoA 2-hydroxylase interacting protein-like | 4.93848 |
| PDZD7 | PDZ domain containing 7 | 4.93064 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) | 4.89939 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | 4.88093 |
| LCTL | lactase-like | 4.81096 |
| FAM228B | family with sequence similarity 228, member B | 4.71676 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | 4.71366 |
| ZC3H14 | zinc finger CCCH-type containing 14 | 4.61617 |
| FADS1 | fatty acid desaturase 1 | 4.59982 |
| MPDU1 | mannose-P-dolichol utilization defect 1 | 4.53751 |
| SZT2 | seizure threshold 2 homolog (mouse) | 4.49206 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 | 4.46158 |
| TRABD2A | TraB domain containing 2A | 4.3848 |
| GADD45GIP1 | growth arrest and DNA-damage-inducible, gamma interacting protein 1 | 4.3848 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | 4.37095 |
| LOXL3 | lysyl oxidase-like 3 | 4.27593 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit | 4.25535 |
| PQBP1 | polyglutamine binding protein 1 | 4.22419 |
| WDR83 | WD repeat domain 83 | 4.22011 |
| C5ORF45 | chromosome 5 open reading frame 45 | 4.21964 |
| LY6K | lymphocyte antigen 6 complex, locus K | 4.21899 |
| CCDC107 | coiled-coil domain containing 107 | 4.17146 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 | 4.15811 |
| JSRP1 | junctional sarcoplasmic reticulum protein 1 | 4.08948 |
| SVIL | supervillin | 4.00791 |
| MRPL34 | mitochondrial ribosomal protein L34 | 3.98163 |
| WDR41 | WD repeat domain 41 | 3.96409 |
| WDR38 | WD repeat domain 38 | 3.87942 |
| RFXANK | regulatory factor X-associated ankyrin-containing protein | 3.79011 |
| MSMP | microseminoprotein, prostate associated | 3.78539 |
| TECPR1 | tectonin beta-propeller repeat containing 1 | 3.71509 |
| SPATA6L | spermatogenesis associated 6-like | 3.63095 |
| CAPN12 | calpain 12 | 3.6181 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SYNC | syncoilin, intermediate filament protein | -20.0 |
| FBXL3 | F-box and leucine-rich repeat protein 3 | -20.0 |
| CLN5 | ceroid-lipofuscinosis, neuronal 5 | -20.0 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | -15.2223 |
| CHM | choroideremia (Rab escort protein 1) | -12.7222 |
| FMO1 | flavin containing monooxygenase 1 | -10.7115 |
| E2F5 | E2F transcription factor 5, p130-binding | -9.56108 |
| CEP295 | centrosomal protein 295kDa | -9.17823 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -8.73762 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -8.70462 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 | -8.64497 |
| BORA | bora, aurora kinase A activator | -8.491 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 | -8.23538 |
| GLT8D1 | glycosyltransferase 8 domain containing 1 | -7.66577 |
| MARCH1 | membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase | -7.63531 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | -7.52114 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -7.23634 |
| U2SURP | U2 snRNP-associated SURP domain containing | -7.0338 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -6.89402 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | -6.52636 |
| PLCE1 | phospholipase C, epsilon 1 | -6.38589 |
| NEXN | nexilin (F actin binding protein) | -6.25827 |
| USP1 | ubiquitin specific peptidase 1 | -6.19636 |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 | -6.15775 |
| CTR9 | CTR9, Paf1/RNA polymerase II complex component | -6.14775 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | -6.11609 |
| BCLAF1 | BCL2-associated transcription factor 1 | -5.90451 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -5.83307 |
| SET | SET nuclear proto-oncogene | -5.71684 |
| TPR | translocated promoter region, nuclear basket protein | -5.64963 |
| H2AFZ | H2A histone family, member Z | -5.60152 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -5.52723 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 | -5.51903 |
| RAN | RAN, member RAS oncogene family | -5.48363 |
| PARP1 | poly (ADP-ribose) polymerase 1 | -5.44817 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -5.29361 |
| FAM69A | family with sequence similarity 69, member A | -5.25247 |
| RPL7 | ribosomal protein L7 | -5.24507 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -5.19773 |
| FAM175A | family with sequence similarity 175, member A | -5.14953 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -5.13846 |
| GLO1 | glyoxalase I | -5.09293 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -5.07264 |
| PLS3 | plastin 3 | -5.061 |
| CANX | calnexin | -5.0052 |
| ZBED9 | zinc finger, BED-type containing 9 | -4.98149 |
| CYCS | cytochrome c, somatic | -4.94404 |
| CENPE | centromere protein E, 312kDa | -4.90354 |
| MTDH | metadherin | -4.82592 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -4.77864 |
| TMEM126A | transmembrane protein 126A | -4.73499 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -4.71676 |
| ZNF24 | zinc finger protein 24 | -4.70618 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | -4.68241 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -4.62893 |
| RPL34 | ribosomal protein L34 | -4.60937 |
| RPS20 | ribosomal protein S20 | -4.57793 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -4.52716 |
| MSH3 | mutS homolog 3 | -4.52511 |
| UHRF1BP1 | UHRF1 binding protein 1 | -4.46776 |
| PLLP | plasmolipin | -4.3848 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -4.38368 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -4.38082 |
| CAPRIN1 | cell cycle associated protein 1 | -4.3741 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -4.33696 |
| RPL10A | ribosomal protein L10a | -4.25468 |
| SFPQ | splicing factor proline/glutamine-rich | -4.23364 |
| RBMX | RNA binding motif protein, X-linked | -4.22419 |
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | -4.22419 |
| KTN1 | kinectin 1 (kinesin receptor) | -4.17468 |
| TPM3 | tropomyosin 3 | -4.14392 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -4.13123 |
| HTATSF1 | HIV-1 Tat specific factor 1 | -4.13123 |
| PPA1 | pyrophosphatase (inorganic) 1 | -4.12289 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -4.06902 |
| CKAP2 | cytoskeleton associated protein 2 | -4.05331 |
| GSE1 | Gse1 coiled-coil protein | -4.04551 |
| CKAP5 | cytoskeleton associated protein 5 | -4.02808 |
| CTSA | cathepsin A | -4.01174 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | -3.97415 |
| EXOSC9 | exosome component 9 | -3.96435 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -3.96409 |
| CDC42 | cell division cycle 42 | -3.9363 |
| USP16 | ubiquitin specific peptidase 16 | -3.93438 |
| C8ORF59 | chromosome 8 open reading frame 59 | -3.93383 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -3.88947 |
| WDR43 | WD repeat domain 43 | -3.88594 |
| MCM4 | minichromosome maintenance complex component 4 | -3.85839 |
| GYG1 | glycogenin 1 | -3.81706 |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 | -3.78848 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.78539 |
| HIST1H1D | histone cluster 1, H1d | -3.7636 |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial | -3.73923 |
| RPL21 | ribosomal protein L21 | -3.70658 |
| NCBP2L | nuclear cap binding protein subunit 2-like | -3.69777 |
| TARS | threonyl-tRNA synthetase | -3.65522 |
| NOP58 | NOP58 ribonucleoprotein | -3.65401 |
| FAM208A | family with sequence similarity 208, member A | -3.62233 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -3.6197 |
| CCNA2 | cyclin A2 | -3.61789 |
