| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting PRP5 in HEK293T cell line (Study accession: SRP340978) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_7571_KD_PRP5_SRP340978 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 20.0 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 20.0 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 20.0 |
| YARS | tyrosyl-tRNA synthetase | 20.0 |
| SOX4 | SRY (sex determining region Y)-box 4 | 20.0 |
| PTMA | prothymosin, alpha | 20.0 |
| RPS13 | ribosomal protein S13 | 20.0 |
| RPS14 | ribosomal protein S14 | 20.0 |
| RPS19 | ribosomal protein S19 | 20.0 |
| PTPRU | protein tyrosine phosphatase, receptor type, U | 20.0 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 20.0 |
| ACTG1 | actin gamma 1 | 20.0 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 20.0 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 20.0 |
| FSCN1 | fascin actin-bundling protein 1 | 20.0 |
| RPL39 | ribosomal protein L39 | 20.0 |
| RPL35 | ribosomal protein L35 | 20.0 |
| RPL32 | ribosomal protein L32 | 20.0 |
| BSG | basigin (Ok blood group) | 20.0 |
| HMGA1 | high mobility group AT-hook 1 | 20.0 |
| RPLP2 | ribosomal protein, large, P2 | 20.0 |
| RPLP1 | ribosomal protein, large, P1 | 20.0 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 20.0 |
| MDH2 | malate dehydrogenase 2, NAD (mitochondrial) | 20.0 |
| ARF1 | ADP-ribosylation factor 1 | 20.0 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 20.0 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 20.0 |
| RPS2 | ribosomal protein S2 | 20.0 |
| VDAC1 | voltage-dependent anion channel 1 | 20.0 |
| RPS8 | ribosomal protein S8 | 20.0 |
| RPSA | ribosomal protein SA | 20.0 |
| RPL28 | ribosomal protein L28 | 20.0 |
| RPL24 | ribosomal protein L24 | 20.0 |
| RPL21 | ribosomal protein L21 | 20.0 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 20.0 |
| EIF4H | eukaryotic translation initiation factor 4H | 20.0 |
| HSPA8 | heat shock 70kDa protein 8 | 20.0 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 20.0 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 20.0 |
| RPL14 | ribosomal protein L14 | 20.0 |
| RPL10 | ribosomal protein L10 | 20.0 |
| RPL11 | ribosomal protein L11 | 20.0 |
| MORF4L2 | mortality factor 4 like 2 | 20.0 |
| MORF4L1 | mortality factor 4 like 1 | 20.0 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 20.0 |
| TAGLN2 | transgelin 2 | 20.0 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 20.0 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 20.0 |
| RPS27A | ribosomal protein S27a | 20.0 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 20.0 |
| FBL | fibrillarin | 20.0 |
| RPS25 | ribosomal protein S25 | 20.0 |
| RPS20 | ribosomal protein S20 | 20.0 |
| PGK1 | phosphoglycerate kinase 1 | 20.0 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 20.0 |
| RPL9 | ribosomal protein L9 | 20.0 |
| RPL4 | ribosomal protein L4 | 20.0 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 20.0 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 20.0 |
| HSPA1B | heat shock 70kDa protein 1B | 20.0 |
| FLNA | filamin A, alpha | 20.0 |
| RPS24 | ribosomal protein S24 | 20.0 |
| RPL37A | ribosomal protein L37a | 20.0 |
| HDGF | hepatoma-derived growth factor | 20.0 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | 20.0 |
| RPL18A | ribosomal protein L18a | 20.0 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 20.0 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 20.0 |
| CALR | calreticulin | 20.0 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | 20.0 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 20.0 |
| GLUL | glutamate-ammonia ligase | 20.0 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 20.0 |
| RRM2 | ribonucleotide reductase M2 | 20.0 |
| PSAP | prosaposin | 20.0 |
| APP | amyloid beta (A4) precursor protein | 20.0 |
| RHOB | ras homolog family member B | 20.0 |
| RHOA | ras homolog family member A | 20.0 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 20.0 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 20.0 |
| RPL37 | ribosomal protein L37 | 20.0 |
| RPL31 | ribosomal protein L31 | 20.0 |
| KDM5C | lysine (K)-specific demethylase 5C | 20.0 |
| PRPS1 | phosphoribosyl pyrophosphate synthetase 1 | 20.0 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 20.0 |
| EIF1 | eukaryotic translation initiation factor 1 | 20.0 |
| PRDX1 | peroxiredoxin 1 | 20.0 |
| PLS3 | plastin 3 | 20.0 |
| PFN1 | profilin 1 | 20.0 |
| TXNIP | thioredoxin interacting protein | 20.0 |
| BRD2 | bromodomain containing 2 | 20.0 |
| SRRM2 | serine/arginine repetitive matrix 2 | 20.0 |
| H3F3A | H3 histone, family 3A | 20.0 |
| CANX | calnexin | 20.0 |
| AK2 | adenylate kinase 2 | 20.0 |
| HLA-C | major histocompatibility complex, class I, C | 20.0 |
| JUN | jun proto-oncogene | 20.0 |
| BTF3 | basic transcription factor 3 | 20.0 |
| GSTP1 | glutathione S-transferase pi 1 | 20.0 |
| GANAB | glucosidase, alpha; neutral AB | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TTPAL | tocopherol (alpha) transfer protein-like | -20.0 |
| ZNF107 | zinc finger protein 107 | -20.0 |
| CCDC142 | coiled-coil domain containing 142 | -20.0 |
| ZNF75A | zinc finger protein 75a | -20.0 |
| ZNF37A | zinc finger protein 37A | -20.0 |
| CCDC64B | coiled-coil domain containing 64B | -20.0 |
| SLC16A13 | solute carrier family 16, member 13 | -20.0 |
| MOCS3 | molybdenum cofactor synthesis 3 | -20.0 |
| LRRC8B | leucine rich repeat containing 8 family, member B | -20.0 |
| SKIDA1 | SKI/DACH domain containing 1 | -20.0 |
| ZBTB9 | zinc finger and BTB domain containing 9 | -20.0 |
| TTN | titin | -20.0 |
| MFAP3 | microfibrillar-associated protein 3 | -20.0 |
| ZNF189 | zinc finger protein 189 | -20.0 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | -20.0 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 | -20.0 |
| AGFG2 | ArfGAP with FG repeats 2 | -20.0 |
| GPANK1 | G patch domain and ankyrin repeats 1 | -20.0 |
| KIF24 | kinesin family member 24 | -20.0 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -20.0 |
| ZNF614 | zinc finger protein 614 | -20.0 |
| ZSCAN25 | zinc finger and SCAN domain containing 25 | -20.0 |
| B3GALTL | beta 1,3-galactosyltransferase-like | -20.0 |
| ANKRD12 | ankyrin repeat domain 12 | -20.0 |
| ZNF780A | zinc finger protein 780A | -20.0 |
| ZNF780B | zinc finger protein 780B | -20.0 |
| OCLN | occludin | -20.0 |
| RAB36 | RAB36, member RAS oncogene family | -20.0 |
| ZNF608 | zinc finger protein 608 | -20.0 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -20.0 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -20.0 |
| ATRIP | ATR interacting protein | -20.0 |
| FOXN4 | forkhead box N4 | -20.0 |
| ESCO2 | establishment of sister chromatid cohesion N-acetyltransferase 2 | -20.0 |
| PLEKHA3 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 | -20.0 |
| HPS6 | Hermansky-Pudlak syndrome 6 | -20.0 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -20.0 |
| MFSD1 | major facilitator superfamily domain containing 1 | -20.0 |
| LENG9 | leukocyte receptor cluster (LRC) member 9 | -20.0 |
| ZNF594 | zinc finger protein 594 | -20.0 |
| LCMT2 | leucine carboxyl methyltransferase 2 | -20.0 |
| DOLK | dolichol kinase | -20.0 |
| TMEM19 | transmembrane protein 19 | -20.0 |
| S1PR3 | sphingosine-1-phosphate receptor 3 | -20.0 |
| POGLUT1 | protein O-glucosyltransferase 1 | -20.0 |
| ZNF28 | zinc finger protein 28 | -20.0 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | -20.0 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 | -20.0 |
| CCDC125 | coiled-coil domain containing 125 | -20.0 |
| KIAA0040 | KIAA0040 | -20.0 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -20.0 |
| ZNF510 | zinc finger protein 510 | -20.0 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -20.0 |
| TRAK2 | trafficking protein, kinesin binding 2 | -20.0 |
| ZNF274 | zinc finger protein 274 | -20.0 |
| CFAP44 | cilia and flagella associated protein 44 | -20.0 |
| TEX15 | testis expressed 15 | -20.0 |
| ZNF33B | zinc finger protein 33B | -20.0 |
| ZNF81 | zinc finger protein 81 | -20.0 |
| ZFHX2 | zinc finger homeobox 2 | -20.0 |
| FJX1 | four jointed box 1 (Drosophila) | -20.0 |
| DLX1 | distal-less homeobox 1 | -20.0 |
| HOXA3 | homeobox A3 | -20.0 |
| HOXA6 | homeobox A6 | -20.0 |
| HOXA11 | homeobox A11 | -20.0 |
| ZNF302 | zinc finger protein 302 | -20.0 |
| C12ORF4 | chromosome 12 open reading frame 4 | -20.0 |
| RNF170 | ring finger protein 170 | -20.0 |
| MEIS2 | Meis homeobox 2 | -20.0 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -20.0 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -20.0 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | -20.0 |
| SLC38A7 | solute carrier family 38, member 7 | -20.0 |
| HOXA7 | homeobox A7 | -20.0 |
| TIGD5 | tigger transposable element derived 5 | -20.0 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 | -20.0 |
| CSPG5 | chondroitin sulfate proteoglycan 5 (neuroglycan C) | -20.0 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | -20.0 |
| FZD9 | frizzled class receptor 9 | -20.0 |
| ZBTB1 | zinc finger and BTB domain containing 1 | -20.0 |
| CD83 | CD83 molecule | -20.0 |
| ZBED9 | zinc finger, BED-type containing 9 | -20.0 |
| ZNF829 | zinc finger protein 829 | -20.0 |
| CACNG8 | calcium channel, voltage-dependent, gamma subunit 8 | -20.0 |
| HOXB8 | homeobox B8 | -20.0 |
| ICK | intestinal cell (MAK-like) kinase | -20.0 |
| CTNS | cystinosin, lysosomal cystine transporter | -20.0 |
| RNFT2 | ring finger protein, transmembrane 2 | -20.0 |
| FOXP1 | forkhead box P1 | -20.0 |
| ZNF786 | zinc finger protein 786 | -20.0 |
| FAM222A | family with sequence similarity 222, member A | -20.0 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -20.0 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -20.0 |
| ZC3H10 | zinc finger CCCH-type containing 10 | -20.0 |
| SMAD9 | SMAD family member 9 | -20.0 |
| MECOM | MDS1 and EVI1 complex locus | -20.0 |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) | -20.0 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -20.0 |
| KRT9 | keratin 9, type I | -20.0 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -20.0 |
