Perturb_7722_KD_YTHDF2_SRP394934 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting YTHDF2 in HeLa cell line (Study accession: SRP394934) (PerturbAtlas)
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Genes

17 genes differentially expressed following the Perturb_7722_KD_YTHDF2_SRP394934 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
BEST1 bestrophin 1 16.5753
C5ORF45 chromosome 5 open reading frame 45 12.5788
SARM1 sterile alpha and TIR motif containing 1 5.06624
EMG1 EMG1 N1-specific pseudouridine methyltransferase 3.08925
LRRC75A leucine rich repeat containing 75A 2.72611
DNASE1 deoxyribonuclease I 1.94413
SNAP47 synaptosomal-associated protein, 47kDa 1.69108
RSPH9 radial spoke head 9 homolog (Chlamydomonas) 1.30148

decreased expression

Symbol Name Standardized Value
JRK Jrk homolog (mouse) -3.08925
RPS28 ribosomal protein S28 -2.02395
MAP3K15 mitogen-activated protein kinase kinase kinase 15 -1.88449
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) -1.7221
EEF2 eukaryotic translation elongation factor 2 -1.61597
JMJD8 jumonji domain containing 8 -1.60289
ENOSF1 enolase superfamily member 1 -1.50148
CISD3 CDGSH iron sulfur domain 3 -1.36295
ABI2 abl-interactor 2 -1.30148