| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting ACIN1 in HeLa cell line (Study accession: SRP075202) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_7808_KD_ACIN1_SRP075202 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RDH10 | retinol dehydrogenase 10 (all-trans) | 20.0 |
| FSCN1 | fascin actin-bundling protein 1 | 20.0 |
| ATF4 | activating transcription factor 4 | 20.0 |
| EIF6 | eukaryotic translation initiation factor 6 | 20.0 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 20.0 |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | 20.0 |
| RBMX | RNA binding motif protein, X-linked | 20.0 |
| CORO1C | coronin, actin binding protein, 1C | 20.0 |
| LBR | lamin B receptor | 20.0 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 20.0 |
| TM4SF1 | transmembrane 4 L six family member 1 | 20.0 |
| TPM3 | tropomyosin 3 | 20.0 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 20.0 |
| TFRC | transferrin receptor | 20.0 |
| SMC4 | structural maintenance of chromosomes 4 | 20.0 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 20.0 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 20.0 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 20.0 |
| COTL1 | coactosin-like F-actin binding protein 1 | 20.0 |
| INTS1 | integrator complex subunit 1 | 20.0 |
| ASS1 | argininosuccinate synthase 1 | 20.0 |
| CTPS1 | CTP synthase 1 | 20.0 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked | 20.0 |
| TPX2 | TPX2, microtubule-associated | 20.0 |
| TMEM245 | transmembrane protein 245 | 20.0 |
| TRIM33 | tripartite motif containing 33 | 20.0 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | 20.0 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 20.0 |
| RAI14 | retinoic acid induced 14 | 20.0 |
| SFPQ | splicing factor proline/glutamine-rich | 20.0 |
| PALLD | palladin, cytoskeletal associated protein | 20.0 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 20.0 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 20.0 |
| SLMO2 | slowmo homolog 2 (Drosophila) | 20.0 |
| STMN1 | stathmin 1 | 20.0 |
| BZW1 | basic leucine zipper and W2 domains 1 | 20.0 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 20.0 |
| PODXL | podocalyxin-like | 20.0 |
| ANLN | anillin, actin binding protein | 20.0 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 20.0 |
| H1F0 | H1 histone family, member 0 | 20.0 |
| RACGAP1 | Rac GTPase activating protein 1 | 20.0 |
| ECT2 | epithelial cell transforming 2 | 20.0 |
| PTMA | prothymosin, alpha | 20.0 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 20.0 |
| TARS | threonyl-tRNA synthetase | 20.0 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 | 20.0 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 20.0 |
| CD46 | CD46 molecule, complement regulatory protein | 20.0 |
| USP1 | ubiquitin specific peptidase 1 | 20.0 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 20.0 |
| AARS | alanyl-tRNA synthetase | 20.0 |
| GLO1 | glyoxalase I | 20.0 |
| CHKB | choline kinase beta | 20.0 |
| CLUH | clustered mitochondria (cluA/CLU1) homolog | 20.0 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 20.0 |
| MUC13 | mucin 13, cell surface associated | 20.0 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 20.0 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 20.0 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 20.0 |
| FASN | fatty acid synthase | 20.0 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 20.0 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 20.0 |
| RRM1 | ribonucleotide reductase M1 | 20.0 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 20.0 |
| MCL1 | myeloid cell leukemia 1 | 20.0 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 20.0 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 20.0 |
| PCSK9 | proprotein convertase subtilisin/kexin type 9 | 20.0 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 20.0 |
| PPA1 | pyrophosphatase (inorganic) 1 | 20.0 |
| SLC38A1 | solute carrier family 38, member 1 | 20.0 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 20.0 |
| RRM2 | ribonucleotide reductase M2 | 20.0 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 20.0 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 20.0 |
| ACLY | ATP citrate lyase | 20.0 |
| TMPO | thymopoietin | 20.0 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 20.0 |
| FSTL1 | follistatin-like 1 | 20.0 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 20.0 |
| GRSF1 | G-rich RNA sequence binding factor 1 | 20.0 |
| CDC20 | cell division cycle 20 | 20.0 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 20.0 |
| NEFH | neurofilament, heavy polypeptide | 20.0 |
| PSAT1 | phosphoserine aminotransferase 1 | 20.0 |
| FUS | FUS RNA binding protein | 20.0 |
| KRT18 | keratin 18, type I | 20.0 |
| AURKA | aurora kinase A | 20.0 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 20.0 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 20.0 |
| FLNA | filamin A, alpha | 20.0 |
| CLIC4 | chloride intracellular channel 4 | 20.0 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 20.0 |
| H3F3A | H3 histone, family 3A | 20.0 |
| KRT8 | keratin 8, type II | 20.0 |
| H2AFV | H2A histone family, member V | 20.0 |
| H2AFZ | H2A histone family, member Z | 20.0 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 20.0 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PRDM1 | PR domain containing 1, with ZNF domain | -20.0 |
| GABRA3 | gamma-aminobutyric acid (GABA) A receptor, alpha 3 | -20.0 |
| RSPO3 | R-spondin 3 | -20.0 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -20.0 |
| TMEM175 | transmembrane protein 175 | -20.0 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 | -20.0 |
| NDST4 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 | -20.0 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -20.0 |
| BTC | betacellulin | -20.0 |
| NEK10 | NIMA-related kinase 10 | -20.0 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -20.0 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -20.0 |
| VAMP5 | vesicle-associated membrane protein 5 | -20.0 |
| ARSD | arylsulfatase D | -20.0 |
| KCNU1 | potassium channel, subfamily U, member 1 | -20.0 |
| TPPP | tubulin polymerization promoting protein | -20.0 |
| MYO16 | myosin XVI | -20.0 |
| BMP2 | bone morphogenetic protein 2 | -20.0 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | -20.0 |
| ATOH8 | atonal homolog 8 (Drosophila) | -20.0 |
| SLC44A3 | solute carrier family 44, member 3 | -20.0 |
| IDUA | iduronidase, alpha-L- | -20.0 |
| STC1 | stanniocalcin 1 | -20.0 |
| PCDH9 | protocadherin 9 | -20.0 |
| SKIDA1 | SKI/DACH domain containing 1 | -20.0 |
| LURAP1L | leucine rich adaptor protein 1-like | -20.0 |
| LOC728392 | uncharacterized LOC728392 | -20.0 |
| FRMD4B | FERM domain containing 4B | -20.0 |
| GATA3 | GATA binding protein 3 | -20.0 |
| LAMA4 | laminin, alpha 4 | -20.0 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 | -20.0 |
| FAM195B | family with sequence similarity 195, member B | -20.0 |
| ALX1 | ALX homeobox 1 | -20.0 |
| COL24A1 | collagen, type XXIV, alpha 1 | -20.0 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -20.0 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -20.0 |
| AIM1 | absent in melanoma 1 | -20.0 |
| TMEM116 | transmembrane protein 116 | -20.0 |
| THSD7A | thrombospondin, type I, domain containing 7A | -20.0 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -20.0 |
| GPR1 | G protein-coupled receptor 1 | -20.0 |
| FAM198B | family with sequence similarity 198, member B | -20.0 |
| LIPC | lipase, hepatic | -20.0 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 | -20.0 |
| VIT | vitrin | -20.0 |
| MSRB2 | methionine sulfoxide reductase B2 | -20.0 |
| LMF1 | lipase maturation factor 1 | -20.0 |
| OPN3 | opsin 3 | -20.0 |
| IL7R | interleukin 7 receptor | -20.0 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -20.0 |
| CFH | complement factor H | -20.0 |
| COL17A1 | collagen, type XVII, alpha 1 | -20.0 |
| ALPPL2 | alkaline phosphatase, placental-like 2 | -20.0 |
| CXORF23 | chromosome X open reading frame 23 | -20.0 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | -20.0 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -20.0 |
| DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 | -20.0 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -20.0 |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa | -20.0 |
| EPB41L4A | erythrocyte membrane protein band 4.1 like 4A | -20.0 |
| SEPP1 | selenoprotein P, plasma, 1 | -20.0 |
| CDRT1 | CMT1A duplicated region transcript 1 | -20.0 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -20.0 |
| MAP2 | microtubule-associated protein 2 | -20.0 |
| ALPI | alkaline phosphatase, intestinal | -20.0 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase | -20.0 |
| GLIPR1 | GLI pathogenesis-related 1 | -20.0 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -20.0 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -20.0 |
| DCN | decorin | -20.0 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -20.0 |
| EPHA5 | EPH receptor A5 | -20.0 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -20.0 |
| MAOB | monoamine oxidase B | -20.0 |
| NOV | nephroblastoma overexpressed | -20.0 |
| MR1 | major histocompatibility complex, class I-related | -20.0 |
| CLCA2 | chloride channel accessory 2 | -20.0 |
| SLCO5A1 | solute carrier organic anion transporter family, member 5A1 | -20.0 |
| SEC31B | SEC31 homolog B (S. cerevisiae) | -20.0 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -20.0 |
| NCKAP5 | NCK-associated protein 5 | -20.0 |
| VIPR1 | vasoactive intestinal peptide receptor 1 | -20.0 |
| SESN3 | sestrin 3 | -20.0 |
| AREG | amphiregulin | -20.0 |
| ANK1 | ankyrin 1, erythrocytic | -20.0 |
| TP53INP1 | tumor protein p53 inducible nuclear protein 1 | -20.0 |
| PPEF1 | protein phosphatase, EF-hand calcium binding domain 1 | -20.0 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -20.0 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | -20.0 |
| ATAT1 | alpha tubulin acetyltransferase 1 | -20.0 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -20.0 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -20.0 |
| ALPK1 | alpha-kinase 1 | -20.0 |
| FAAH2 | fatty acid amide hydrolase 2 | -20.0 |
| PRSS56 | protease, serine, 56 | -20.0 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | -20.0 |
| IL1RAP | interleukin 1 receptor accessory protein | -20.0 |
| AK9 | adenylate kinase 9 | -20.0 |
| CACFD1 | calcium channel flower domain containing 1 | -20.0 |
| CAB39L | calcium binding protein 39-like | -20.0 |
