Perturb_7853_KD_CCNF_SRP212181 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting CCNF in HeLa cell line (Study accession: SRP212181) (PerturbAtlas)
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Genes

108 genes differentially expressed following the Perturb_7853_KD_CCNF_SRP212181 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
CLCC1 chloride channel CLIC-like 1 20.0
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 20.0
KIAA0895 KIAA0895 17.1805
LCORL ligand dependent nuclear receptor corepressor-like 15.8799
TRIM59 tripartite motif containing 59 14.2811
MYH11 myosin, heavy chain 11, smooth muscle 10.9891
EXOSC9 exosome component 9 9.356
FAM166A family with sequence similarity 166, member A 8.79623
ITFG2 integrin alpha FG-GAP repeat containing 2 8.69516
GTPBP1 GTP binding protein 1 7.55068
NT5DC4 5'-nucleotidase domain containing 4 5.89281
CCDC107 coiled-coil domain containing 107 5.67793
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 5.31912
ABI2 abl-interactor 2 5.09937
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 4.96804
CDC23 cell division cycle 23 4.81081
IL18BP interleukin 18 binding protein 4.37735
RBBP4 retinoblastoma binding protein 4 3.56367
KIF7 kinesin family member 7 3.02517
COG8 component of oligomeric golgi complex 8 2.97707
TMPO thymopoietin 2.72571
RPS28 ribosomal protein S28 2.07518
PDZD11 PDZ domain containing 11 2.01341
PLLP plasmolipin 1.93933
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) 1.902
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 1.82231
PRICKLE3 prickle homolog 3 (Drosophila) 1.76939
SNX32 sorting nexin 32 1.72666
INTS8 integrator complex subunit 8 1.69993
PTMS parathymosin 1.67666
UTP23 UTP23, small subunit (SSU) processome component, homolog (yeast) 1.66128
GTPBP2 GTP binding protein 2 1.36533
ZFYVE16 zinc finger, FYVE domain containing 16 1.35837
GFAP glial fibrillary acidic protein 1.33715

decreased expression

Symbol Name Standardized Value
MALSU1 mitochondrial assembly of ribosomal large subunit 1 -20.0
SRR serine racemase -12.5627
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 -11.7709
SARM1 sterile alpha and TIR motif containing 1 -11.0314
DNASE1 deoxyribonuclease I -8.90834
KRT8 keratin 8, type II -8.10866
CSNK1D casein kinase 1, delta -7.53766
ORAOV1 oral cancer overexpressed 1 -6.78703
TTI2 TELO2 interacting protein 2 -6.45778
TSPAN31 tetraspanin 31 -6.14302
SLC7A6OS solute carrier family 7, member 6 opposite strand -5.69993
ERCC1 excision repair cross-complementation group 1 -5.67793
C5ORF45 chromosome 5 open reading frame 45 -4.6621
SAMD11 sterile alpha motif domain containing 11 -4.10274
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase -3.66817
ARL10 ADP-ribosylation factor-like 10 -3.63918
ZNF771 zinc finger protein 771 -3.61502
LRRC75A leucine rich repeat containing 75A -3.56431
ZNHIT3 zinc finger, HIT-type containing 3 -3.55749
C9ORF172 chromosome 9 open reading frame 172 -3.46118
ATP8B4 ATPase, class I, type 8B, member 4 -3.46118
SNAP47 synaptosomal-associated protein, 47kDa -3.36462
THAP3 THAP domain containing, apoptosis associated protein 3 -3.0875
IFT22 intraflagellar transport 22 -3.06744
CCDC42B coiled-coil domain containing 42B -3.04535
CEBPZOS CEBPZ opposite strand -3.01037
DCAF13 DDB1 and CUL4 associated factor 13 -2.92413
SNX22 sorting nexin 22 -2.87552
CCDC73 coiled-coil domain containing 73 -2.75721
LSMEM2 leucine-rich single-pass membrane protein 2 -2.74612
ARSG arylsulfatase G -2.7202
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) -2.7202
NR2C2 nuclear receptor subfamily 2, group C, member 2 -2.65605
RABL6 RAB, member RAS oncogene family-like 6 -2.58268
HIST1H4I histone cluster 1, H4i -2.56572
MYO19 myosin XIX -2.53098
RPAIN RPA interacting protein -2.42452
CEP295 centrosomal protein 295kDa -2.34874
FBXO11 F-box protein 11 -2.34043
CRYBG3 beta-gamma crystallin domain containing 3 -2.31744
MFSD11 major facilitator superfamily domain containing 11 -2.23663
SH3PXD2A SH3 and PX domains 2A -2.14156
LOC122455342 testis-specific serine/proline-rich protein -2.14035
PIGL phosphatidylinositol glycan anchor biosynthesis, class L -2.09083
LHFPL5 lipoma HMGIC fusion partner-like 5 -2.09064
UBE2A ubiquitin-conjugating enzyme E2A -2.07518
PMPCB peptidase (mitochondrial processing) beta -2.03633
KLC1 kinesin light chain 1 -2.01883
NUP88 nucleoporin 88kDa -1.92576
FANCA Fanconi anemia, complementation group A -1.91933
BASP1 brain abundant, membrane attached signal protein 1 -1.85585
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa -1.85553
ZNF593OS ZNF593 opposite strand -1.80715
NARFL nuclear prelamin A recognition factor-like -1.79006
SPNS2 spinster homolog 2 (Drosophila) -1.77582
GLT8D1 glycosyltransferase 8 domain containing 1 -1.76909
SYNC syncoilin, intermediate filament protein -1.76909
SPG11 spastic paraplegia 11 (autosomal recessive) -1.72222
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase -1.69282
DNAH11 dynein, axonemal, heavy chain 11 -1.67372
ENDOG endonuclease G -1.65778
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -1.65219
PIAS1 protein inhibitor of activated STAT, 1 -1.62961
PDZD7 PDZ domain containing 7 -1.62961
ASB6 ankyrin repeat and SOCS box containing 6 -1.59952
NOX1 NADPH oxidase 1 -1.54557
B9D1 B9 protein domain 1 -1.51232
RHOF ras homolog family member F (in filopodia) -1.49424
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -1.45035
CALHM2 calcium homeostasis modulator 2 -1.42393
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase -1.41363
GGCX gamma-glutamyl carboxylase -1.39008
FAM81A family with sequence similarity 81, member A -1.33432
FKRP fukutin related protein -1.30308