| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting LAP2alpha in adipose-derived stem cells cell (Study accession: SRP224617) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_808_KD_LAP2alpha_SRP224617 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 20.0 |
| NEFM | neurofilament, medium polypeptide | 20.0 |
| E2F7 | E2F transcription factor 7 | 20.0 |
| IL33 | interleukin 33 | 20.0 |
| MMP1 | matrix metallopeptidase 1 | 20.0 |
| COL4A6 | collagen, type IV, alpha 6 | 20.0 |
| NDRG4 | NDRG family member 4 | 20.0 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 20.0 |
| PEG10 | paternally expressed 10 | 20.0 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 20.0 |
| PLAT | plasminogen activator, tissue | 20.0 |
| NEFL | neurofilament, light polypeptide | 20.0 |
| NRG1 | neuregulin 1 | 20.0 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 20.0 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 20.0 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 20.0 |
| NPTX1 | neuronal pentraxin I | 20.0 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 20.0 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 20.0 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 20.0 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 20.0 |
| TFPI2 | tissue factor pathway inhibitor 2 | 20.0 |
| IFI44L | interferon-induced protein 44-like | 20.0 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 20.0 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 20.0 |
| IFI44 | interferon-induced protein 44 | 20.0 |
| AADAC | arylacetamide deacetylase | 20.0 |
| POU2F2 | POU class 2 homeobox 2 | 20.0 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | 20.0 |
| RGS4 | regulator of G-protein signaling 4 | 20.0 |
| ADGRL4 | adhesion G protein-coupled receptor L4 | 20.0 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 20.0 |
| LIF | leukemia inhibitory factor | 20.0 |
| CFH | complement factor H | 20.0 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) | 20.0 |
| CSF3 | colony stimulating factor 3 (granulocyte) | 20.0 |
| FOSL1 | FOS-like antigen 1 | 20.0 |
| F2RL2 | coagulation factor II (thrombin) receptor-like 2 | 20.0 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 20.0 |
| SPP1 | secreted phosphoprotein 1 | 20.0 |
| IL1B | interleukin 1, beta | 20.0 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 | 19.699 |
| IL7R | interleukin 7 receptor | 19.699 |
| ARHGAP22 | Rho GTPase activating protein 22 | 19.699 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 19.5229 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 19.3979 |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 | 18.7696 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 18.6778 |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 18.6778 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 18.3372 |
| TRIL | TLR4 interactor with leucine-rich repeats | 18.0132 |
| DUSP6 | dual specificity phosphatase 6 | 17.9066 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 17.8861 |
| IFI27 | interferon, alpha-inducible protein 27 | 17.8239 |
| KIAA1217 | KIAA1217 | 17.6655 |
| COL4A5 | collagen, type IV, alpha 5 | 17.5575 |
| HAND2 | heart and neural crest derivatives expressed 2 | 17.5482 |
| SYT11 | synaptotagmin XI | 17.5287 |
| DUSP3 | dual specificity phosphatase 3 | 17.2262 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 16.1287 |
| NPAS1 | neuronal PAS domain protein 1 | 16.0079 |
| AMPD3 | adenosine monophosphate deaminase 3 | 15.9335 |
| FAM43A | family with sequence similarity 43, member A | 15.8783 |
| FGF5 | fibroblast growth factor 5 | 15.3522 |
| IL1A | interleukin 1, alpha | 15.21 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 14.8277 |
| CCND1 | cyclin D1 | 14.781 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 14.7185 |
| CLEC2B | C-type lectin domain family 2, member B | 14.5216 |
| PIDD1 | p53-induced death domain protein 1 | 14.4405 |
| MAPK6 | mitogen-activated protein kinase 6 | 14.2596 |
| TMEFF2 | transmembrane protein with EGF-like and two follistatin-like domains 2 | 14.2521 |
| SAMD9L | sterile alpha motif domain containing 9-like | 14.1385 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 14.084 |
| EDNRB | endothelin receptor type B | 13.903 |
| CEND1 | cell cycle exit and neuronal differentiation 1 | 13.8536 |
| EMCN | endomucin | 13.8381 |
| HAS2 | hyaluronan synthase 2 | 13.7425 |
| ETV1 | ets variant 1 | 13.5571 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | 13.4397 |
| RGS2 | regulator of G-protein signaling 2 | 13.4075 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 13.3096 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | 13.18 |
| MAP2K3 | mitogen-activated protein kinase kinase 3 | 13.0395 |
| HMGA2 | high mobility group AT-hook 2 | 12.9142 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 12.8698 |
| NAP1L5 | nucleosome assembly protein 1-like 5 | 12.7926 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 12.737 |
| CAMK1G | calcium/calmodulin-dependent protein kinase IG | 12.66 |
| TBX2 | T-box 2 | 12.5614 |
| PLAU | plasminogen activator, urokinase | 12.464 |
| FAM167A | family with sequence similarity 167, member A | 12.445 |
| HSPB8 | heat shock 22kDa protein 8 | 12.2569 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 12.1666 |
| CLDN12 | claudin 12 | 12.0872 |
| PRSS3 | protease, serine, 3 | 12.0331 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 11.9082 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 11.7959 |
| RANGAP1 | Ran GTPase activating protein 1 | 11.7911 |
| MYPN | myopalladin | 11.5932 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CTDSP2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 | -20.0 |
| TUFT1 | tuftelin 1 | -20.0 |
| C1R | complement component 1, r subcomponent | -20.0 |
| COL15A1 | collagen, type XV, alpha 1 | -20.0 |
| WASF2 | WAS protein family, member 2 | -20.0 |
| PAPPA2 | pappalysin 2 | -20.0 |
| MFAP4 | microfibrillar-associated protein 4 | -20.0 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | -20.0 |
| MSC | musculin | -20.0 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | -20.0 |
| COLGALT1 | collagen beta(1-O)galactosyltransferase 1 | -20.0 |
| CDK14 | cyclin-dependent kinase 14 | -20.0 |
| BMP6 | bone morphogenetic protein 6 | -20.0 |
| DPYSL3 | dihydropyrimidinase-like 3 | -20.0 |
| TCF3 | transcription factor 3 | -20.0 |
| PITX2 | paired-like homeodomain 2 | -20.0 |
| ADAMTS10 | ADAM metallopeptidase with thrombospondin type 1 motif, 10 | -20.0 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | -20.0 |
| CYGB | cytoglobin | -20.0 |
| SNAI1 | snail family zinc finger 1 | -20.0 |
| VEGFA | vascular endothelial growth factor A | -20.0 |
| CYBRD1 | cytochrome b reductase 1 | -20.0 |
| PODNL1 | podocan-like 1 | -20.0 |
| ASS1 | argininosuccinate synthase 1 | -20.0 |
| FAM129A | family with sequence similarity 129, member A | -20.0 |
| PNMA2 | paraneoplastic Ma antigen 2 | -20.0 |
| PRR15 | proline rich 15 | -20.0 |
| DMKN | dermokine | -20.0 |
| C3 | complement component 3 | -20.0 |
| TMEM119 | transmembrane protein 119 | -20.0 |
| PTK2B | protein tyrosine kinase 2 beta | -20.0 |
| DSTN | destrin (actin depolymerizing factor) | -20.0 |
| RPL24 | ribosomal protein L24 | -20.0 |
| KLHDC7B | kelch domain containing 7B | -20.0 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | -20.0 |
| RCAN3 | RCAN family member 3 | -20.0 |
| RUNX1 | runt-related transcription factor 1 | -20.0 |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 | -20.0 |
| GLS | glutaminase | -20.0 |
| PKP2 | plakophilin 2 | -20.0 |
| TXNDC5 | thioredoxin domain containing 5 (endoplasmic reticulum) | -20.0 |
| PI16 | peptidase inhibitor 16 | -20.0 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -20.0 |
| COLEC12 | collectin sub-family member 12 | -20.0 |
| MEGF6 | multiple EGF-like-domains 6 | -20.0 |
| INHBE | inhibin, beta E | -20.0 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -20.0 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -20.0 |
| PEX5 | peroxisomal biogenesis factor 5 | -20.0 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -20.0 |
| TAGLN | transgelin | -20.0 |
| AEBP1 | AE binding protein 1 | -20.0 |
| FIBIN | fin bud initiation factor homolog (zebrafish) | -20.0 |
| SH2D4A | SH2 domain containing 4A | -20.0 |
| FAM20A | family with sequence similarity 20, member A | -20.0 |
| FAM20C | family with sequence similarity 20, member C | -20.0 |
| PHGDH | phosphoglycerate dehydrogenase | -20.0 |
| MXI1 | MAX interactor 1, dimerization protein | -20.0 |
| PAWR | PRKC, apoptosis, WT1, regulator | -20.0 |
| S100A16 | S100 calcium binding protein A16 | -20.0 |
| ADGRA2 | adhesion G protein-coupled receptor A2 | -20.0 |
| SNED1 | sushi, nidogen and EGF-like domains 1 | -20.0 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -20.0 |
| ITGA11 | integrin, alpha 11 | -20.0 |
| ALPL | alkaline phosphatase, liver/bone/kidney | -20.0 |
| DDIT4 | DNA-damage-inducible transcript 4 | -20.0 |
| PCSK9 | proprotein convertase subtilisin/kexin type 9 | -20.0 |
| CCNA2 | cyclin A2 | -20.0 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | -20.0 |
| SLC35F6 | solute carrier family 35, member F6 | -20.0 |
| GPC6 | glypican 6 | -20.0 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | -20.0 |
| RAN | RAN, member RAS oncogene family | -20.0 |
| ITGA10 | integrin, alpha 10 | -20.0 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -20.0 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -20.0 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -20.0 |
| GXYLT2 | glucoside xylosyltransferase 2 | -20.0 |
| ATL3 | atlastin GTPase 3 | -20.0 |
| ADM2 | adrenomedullin 2 | -20.0 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | -20.0 |
| NNMT | nicotinamide N-methyltransferase | -20.0 |
| TGM2 | transglutaminase 2 | -20.0 |
| MEST | mesoderm specific transcript | -20.0 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -20.0 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -20.0 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -20.0 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 | -20.0 |
| FZD7 | frizzled class receptor 7 | -20.0 |
| FYCO1 | FYVE and coiled-coil domain containing 1 | -20.0 |
| CLIC3 | chloride intracellular channel 3 | -20.0 |
| SULF1 | sulfatase 1 | -20.0 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -20.0 |
| APOE | apolipoprotein E | -20.0 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | -20.0 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | -20.0 |
| TAF6 | TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa | -20.0 |
| ACLY | ATP citrate lyase | -20.0 |
| ABHD2 | abhydrolase domain containing 2 | -20.0 |
| LMCD1 | LIM and cysteine-rich domains 1 | -20.0 |
