| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting IGF2BP3 in hepatoblastoma cell HepG2 cell line (Study accession: SRP013565) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_8139_KD_IGF2BP3_SRP013565 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TUBA1C | tubulin, alpha 1c | 20.0 |
| OR2I1P | olfactory receptor, family 2, subfamily I, member 1 pseudogene | 20.0 |
| THUMPD1 | THUMP domain containing 1 | 14.1346 |
| PGF | placental growth factor | 11.9779 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | 9.77775 |
| FSIP1 | fibrous sheath interacting protein 1 | 8.41668 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 7.95871 |
| LHX4 | LIM homeobox 4 | 7.44041 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | 7.38417 |
| RYR3 | ryanodine receptor 3 | 6.85018 |
| ACSM1 | acyl-CoA synthetase medium-chain family member 1 | 6.65228 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | 6.31068 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | 6.12091 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 5.96606 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 5.82829 |
| SLC24A5 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 | 5.27818 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 | 5.14335 |
| KRTAP5-9 | keratin associated protein 5-9 | 5.1057 |
| FAM228B | family with sequence similarity 228, member B | 4.91026 |
| CTNS | cystinosin, lysosomal cystine transporter | 4.90576 |
| C19ORF60 | chromosome 19 open reading frame 60 | 4.81396 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 4.54243 |
| NRG4 | neuregulin 4 | 4.53959 |
| SPATA7 | spermatogenesis associated 7 | 4.47832 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 4.45529 |
| LAMTOR4 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 | 4.25474 |
| CD37 | CD37 molecule | 4.17667 |
| GPM6B | glycoprotein M6B | 3.98791 |
| C2ORF88 | chromosome 2 open reading frame 88 | 3.83624 |
| PAQR3 | progestin and adipoQ receptor family member III | 3.81727 |
| FAS | Fas cell surface death receptor | 3.78959 |
| SFT2D3 | SFT2 domain containing 3 | 3.46841 |
| TTN | titin | 3.29931 |
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | 3.2326 |
| LDLRAD2 | low density lipoprotein receptor class A domain containing 2 | 3.22513 |
| FSIP2 | fibrous sheath interacting protein 2 | 3.20091 |
| ZNF337 | zinc finger protein 337 | 3.15901 |
| CLDN20 | claudin 20 | 3.09459 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 3.0677 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 2.98433 |
| ASB16 | ankyrin repeat and SOCS box containing 16 | 2.8577 |
| STRADB | STE20-related kinase adaptor beta | 2.8257 |
| CBR4 | carbonyl reductase 4 | 2.78348 |
| LAMA2 | laminin, alpha 2 | 2.78175 |
| USP34 | ubiquitin specific peptidase 34 | 2.72962 |
| DHRS1 | dehydrogenase/reductase (SDR family) member 1 | 2.65576 |
| RGL4 | ral guanine nucleotide dissociation stimulator-like 4 | 2.64476 |
| CENPP | centromere protein P | 2.6277 |
| NID2 | nidogen 2 (osteonidogen) | 2.6015 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 2.58986 |
| CDC42SE1 | CDC42 small effector 1 | 2.53568 |
| ADAMTSL4 | ADAMTS-like 4 | 2.45785 |
| UQCC2 | ubiquinol-cytochrome c reductase complex assembly factor 2 | 2.45258 |
| ANKDD1A | ankyrin repeat and death domain containing 1A | 2.39381 |
| ZNF394 | zinc finger protein 394 | 2.37734 |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 2.335 |
| ZNF397 | zinc finger protein 397 | 2.27731 |
| SPDYE6 | speedy/RINGO cell cycle regulator family member E6 | 2.2577 |
| PDAP1 | PDGFA associated protein 1 | 2.25748 |
| PRIMPOL | primase and polymerase (DNA-directed) | 2.24781 |
| CHAC2 | ChaC, cation transport regulator homolog 2 (E. coli) | 2.2273 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 | 2.19545 |
| TSSK6 | testis-specific serine kinase 6 | 2.18978 |
| ZNF124 | zinc finger protein 124 | 2.18322 |
| ZNF562 | zinc finger protein 562 | 2.16027 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | 2.14756 |
| FRMD4A | FERM domain containing 4A | 2.10741 |
| PLK5 | polo-like kinase 5 | 2.07755 |
| GGCX | gamma-glutamyl carboxylase | 2.07497 |
| SP100 | SP100 nuclear antigen | 2.06185 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | 2.04951 |
| ZNF850 | zinc finger protein 850 | 2.03653 |
| CCDC39 | coiled-coil domain containing 39 | 2.0197 |
| MARCH1 | membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase | 2.00483 |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 | 2.00122 |
| LYRM5 | LYR motif containing 5 | 1.99713 |
| WRAP53 | WD repeat containing, antisense to TP53 | 1.99391 |
| ZHX3 | zinc fingers and homeoboxes 3 | 1.99335 |
| ASMTL | acetylserotonin O-methyltransferase-like | 1.97635 |
| CCSAP | centriole, cilia and spindle-associated protein | 1.97336 |
| ATP5J2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 | 1.96843 |
| MEGF11 | multiple EGF-like-domains 11 | 1.965 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 1.92187 |
| RBPMS | RNA binding protein with multiple splicing | 1.92187 |
| CCDC146 | coiled-coil domain containing 146 | 1.92187 |
| NUDCD2 | NudC domain containing 2 | 1.91886 |
| SLTM | SAFB-like, transcription modulator | 1.91593 |
| MFSD11 | major facilitator superfamily domain containing 11 | 1.91118 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | 1.90915 |
| AFG3L2 | AFG3-like AAA ATPase 2 | 1.90011 |
| SRP19 | signal recognition particle 19kDa | 1.88752 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | 1.87832 |
| CRBN | cereblon | 1.87036 |
| TRABD2A | TraB domain containing 2A | 1.8521 |
| CHRNA7 | cholinergic receptor, nicotinic, alpha 7 (neuronal) | 1.82784 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 1.81614 |
| PQLC3 | PQ loop repeat containing 3 | 1.80971 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 1.79606 |
| MCM9 | minichromosome maintenance complex component 9 | 1.79152 |
| PKD2L2 | polycystic kidney disease 2-like 2 | 1.76189 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HCN3 | hyperpolarization activated cyclic nucleotide gated potassium channel 3 | -20.0 |
| C17ORF100 | chromosome 17 open reading frame 100 | -20.0 |
| CGREF1 | cell growth regulator with EF-hand domain 1 | -20.0 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -14.9601 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -14.6967 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -14.5716 |
| PCYT1A | phosphate cytidylyltransferase 1, choline, alpha | -14.5335 |
| H1F0 | H1 histone family, member 0 | -14.4441 |
| CRIP3 | cysteine-rich protein 3 | -13.6419 |
| SERPINA12 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 | -13.443 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -12.2598 |
| FABP1 | fatty acid binding protein 1, liver | -11.9506 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | -11.941 |
| LRRC47 | leucine rich repeat containing 47 | -11.8641 |
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 | -11.6753 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -11.4583 |
| UFSP2 | UFM1-specific peptidase 2 | -11.1072 |
| TRAPPC4 | trafficking protein particle complex 4 | -10.7682 |
| GPC3 | glypican 3 | -10.636 |
| HEPACAM | hepatic and glial cell adhesion molecule | -10.6015 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -10.5778 |
| C7ORF49 | chromosome 7 open reading frame 49 | -10.4849 |
| LTB4R2 | leukotriene B4 receptor 2 | -9.99061 |
| AHSG | alpha-2-HS-glycoprotein | -9.78098 |
| FAM35A | family with sequence similarity 35, member A | -9.63475 |
| ENO1 | enolase 1, (alpha) | -9.12684 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria | -9.07464 |
| RPL7 | ribosomal protein L7 | -8.19365 |
| RPS14 | ribosomal protein S14 | -8.04257 |
| TPT1 | tumor protein, translationally-controlled 1 | -7.84765 |
| PEG3 | paternally expressed 3 | -7.82316 |
| ATP5E | ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit | -7.63161 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 | -7.60134 |
| CROCC2 | ciliary rootlet coiled-coil, rootletin family member 2 | -7.59287 |
| IGSF3 | immunoglobulin superfamily, member 3 | -7.53378 |
| ACSF2 | acyl-CoA synthetase family member 2 | -7.52247 |
| WBP1L | WW domain binding protein 1-like | -7.38417 |
| CFAP74 | cilia and flagella associated protein 74 | -7.28861 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -7.22451 |
| IQCE | IQ motif containing E | -7.02293 |
| S100A13 | S100 calcium binding protein A13 | -6.92067 |
| DBH | dopamine beta-hydroxylase (dopamine beta-monooxygenase) | -6.90985 |
| PNCK | pregnancy up-regulated nonubiquitous CaM kinase | -6.90347 |
| USP37 | ubiquitin specific peptidase 37 | -6.77203 |
| C6ORF47 | chromosome 6 open reading frame 47 | -6.63185 |
| KAZN | kazrin, periplakin interacting protein | -6.43255 |
| LRRC75A | leucine rich repeat containing 75A | -6.09631 |
| CCDC152 | coiled-coil domain containing 152 | -6.08531 |
| AFF4 | AF4/FMR2 family, member 4 | -6.00766 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -5.77198 |
| CCDC176 | coiled-coil domain containing 176 | -5.77038 |
| CYB561A3 | cytochrome b561 family, member A3 | -5.75496 |
| PTMS | parathymosin | -5.66076 |
| A2M | alpha-2-macroglobulin | -5.62555 |
| RPL11 | ribosomal protein L11 | -5.59878 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -5.59523 |
| ARHGEF39 | Rho guanine nucleotide exchange factor (GEF) 39 | -5.5811 |
| NDRG2 | NDRG family member 2 | -5.53999 |
| RPL3 | ribosomal protein L3 | -5.32313 |
| CANX | calnexin | -5.29652 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -5.29652 |
| RPL9 | ribosomal protein L9 | -5.26971 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -5.21988 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 | -5.20416 |
| CSNK1D | casein kinase 1, delta | -5.10555 |
| SCTR | secretin receptor | -5.05078 |
| SLC25A35 | solute carrier family 25, member 35 | -4.93653 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 | -4.81396 |
| PEG10 | paternally expressed 10 | -4.81396 |
| CCNK | cyclin K | -4.80073 |
| BEST1 | bestrophin 1 | -4.72611 |
| LRRC3 | leucine rich repeat containing 3 | -4.65952 |
| PTPRN | protein tyrosine phosphatase, receptor type, N | -4.56882 |
| HPD | 4-hydroxyphenylpyruvate dioxygenase | -4.51686 |
| ZFAND2B | zinc finger, AN1-type domain 2B | -4.49131 |
| NEU4 | sialidase 4 | -4.37761 |
| TNS1 | tensin 1 | -4.36829 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain | -4.34891 |
| COA3 | cytochrome c oxidase assembly factor 3 | -4.32837 |
| MIEN1 | migration and invasion enhancer 1 | -4.24154 |
| CLU | clusterin | -4.21764 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -4.21733 |
| EIF4B | eukaryotic translation initiation factor 4B | -4.09525 |
| DCTD | dCMP deaminase | -4.09443 |
| OBSL1 | obscurin-like 1 | -4.07167 |
| MALSU1 | mitochondrial assembly of ribosomal large subunit 1 | -4.07167 |
| ABHD1 | abhydrolase domain containing 1 | -4.07165 |
| PKM | pyruvate kinase, muscle | -4.04803 |
| SH3D19 | SH3 domain containing 19 | -4.03757 |
| PANK2 | pantothenate kinase 2 | -3.93768 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -3.89967 |
| FAM69B | family with sequence similarity 69, member B | -3.86524 |
| RPL13A | ribosomal protein L13a | -3.85623 |
| APOA2 | apolipoprotein A-II | -3.85423 |
| AFP | alpha-fetoprotein | -3.80179 |
| SCAND1 | SCAN domain containing 1 | -3.75035 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -3.73007 |
| DNMT3L | DNA (cytosine-5-)-methyltransferase 3-like | -3.72296 |
| SSR1 | signal sequence receptor, alpha | -3.66276 |
| PRSS23 | protease, serine, 23 | -3.60427 |
