| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting SUPV3L1 in hepatoblastoma cell HepG2 cell line (Study accession: SRP013565) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_8293_KD_SUPV3L1_SRP013565 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LTB4R2 | leukotriene B4 receptor 2 | 20.0 |
| OR2I1P | olfactory receptor, family 2, subfamily I, member 1 pseudogene | 20.0 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) | 20.0 |
| C5ORF45 | chromosome 5 open reading frame 45 | 20.0 |
| TUBA1C | tubulin, alpha 1c | 20.0 |
| LDLRAD2 | low density lipoprotein receptor class A domain containing 2 | 20.0 |
| ACTN4 | actinin, alpha 4 | 20.0 |
| CPM | carboxypeptidase M | 20.0 |
| ZNHIT2 | zinc finger, HIT-type containing 2 | 20.0 |
| SIVA1 | SIVA1, apoptosis-inducing factor | 20.0 |
| FAM228B | family with sequence similarity 228, member B | 20.0 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 20.0 |
| KIF5A | kinesin family member 5A | 20.0 |
| TRO | trophinin | 20.0 |
| SARM1 | sterile alpha and TIR motif containing 1 | 19.3979 |
| CTSA | cathepsin A | 17.9747 |
| CTNS | cystinosin, lysosomal cystine transporter | 17.5482 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 | 17.4763 |
| PGF | placental growth factor | 17.3497 |
| USP24 | ubiquitin specific peptidase 24 | 16.4655 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 16.4585 |
| UQCC3 | ubiquinol-cytochrome c reductase complex assembly factor 3 | 16.1411 |
| GDF9 | growth differentiation factor 9 | 16.1108 |
| C7ORF49 | chromosome 7 open reading frame 49 | 15.9171 |
| C1ORF159 | chromosome 1 open reading frame 159 | 15.0426 |
| WBP1L | WW domain binding protein 1-like | 14.9201 |
| C14ORF93 | chromosome 14 open reading frame 93 | 14.4792 |
| USP37 | ubiquitin specific peptidase 37 | 14.4434 |
| BCAN | brevican | 14.1685 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | 13.2518 |
| RGL4 | ral guanine nucleotide dissociation stimulator-like 4 | 13.1288 |
| FOXH1 | forkhead box H1 | 12.9502 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | 12.8723 |
| LECT2 | leukocyte cell-derived chemotaxin 2 | 12.5444 |
| PLTP | phospholipid transfer protein | 12.2227 |
| DBH | dopamine beta-hydroxylase (dopamine beta-monooxygenase) | 12.0941 |
| PLLP | plasmolipin | 11.9027 |
| TYW1 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) | 11.7634 |
| TNNI1 | troponin I type 1 (skeletal, slow) | 11.7448 |
| CTSB | cathepsin B | 11.337 |
| MMP24-AS1 | MMP24 antisense RNA 1 | 11.3068 |
| RNF157 | ring finger protein 157 | 11.2016 |
| OIT3 | oncoprotein induced transcript 3 | 10.766 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 10.664 |
| MARS | methionyl-tRNA synthetase | 10.6397 |
| METTL12 | methyltransferase like 12 | 10.4013 |
| CEP83 | centrosomal protein 83kDa | 10.102 |
| MALSU1 | mitochondrial assembly of ribosomal large subunit 1 | 10.079 |
| BRI3 | brain protein I3 | 10.0762 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 | 10.0041 |
| EPHA1 | EPH receptor A1 | 9.90103 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 9.71399 |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) | 9.67167 |
| SNIP1 | Smad nuclear interacting protein 1 | 9.62774 |
| RPL10 | ribosomal protein L10 | 9.56004 |
| ELMOD3 | ELMO/CED-12 domain containing 3 | 9.37813 |
| CRIP3 | cysteine-rich protein 3 | 9.37813 |
| TMEM184A | transmembrane protein 184A | 9.36013 |
| FEN1 | flap structure-specific endonuclease 1 | 9.30112 |
| LAMTOR4 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 | 9.28508 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 9.22675 |
| HFE | hemochromatosis | 9.20485 |
| GNAL | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type | 9.09465 |
| TMEM186 | transmembrane protein 186 | 8.86736 |
| KCP | kielin/chordin-like protein | 8.46685 |
| GANC | glucosidase, alpha; neutral C | 8.39108 |
| LINC00514 | long intergenic non-protein coding RNA 514 | 8.34618 |
| DMGDH | dimethylglycine dehydrogenase | 7.76375 |
| C10ORF10 | chromosome 10 open reading frame 10 | 7.68522 |
| DSE | dermatan sulfate epimerase | 7.54261 |
| SNAI3 | snail family zinc finger 3 | 7.47803 |
| MDH2 | malate dehydrogenase 2, NAD (mitochondrial) | 7.29913 |
| FSIP1 | fibrous sheath interacting protein 1 | 7.28407 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) | 7.2818 |
| COG5 | component of oligomeric golgi complex 5 | 7.19607 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 7.13879 |
| DENND1C | DENN/MADD domain containing 1C | 6.85968 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 6.71196 |
| JMJD8 | jumonji domain containing 8 | 6.55452 |
| FBXL19 | F-box and leucine-rich repeat protein 19 | 6.53485 |
| TFB1M | transcription factor B1, mitochondrial | 6.50798 |
| SMIM19 | small integral membrane protein 19 | 6.46494 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) | 6.44936 |
| THAP11 | THAP domain containing 11 | 6.33591 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein | 6.08876 |
| CROCC2 | ciliary rootlet coiled-coil, rootletin family member 2 | 6.01193 |
| PRICKLE3 | prickle homolog 3 (Drosophila) | 5.78319 |
| TRRAP | transformation/transcription domain-associated protein | 5.77455 |
| LSAMP | limbic system-associated membrane protein | 5.66168 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 | 5.63346 |
| DTNA | dystrobrevin, alpha | 5.58184 |
| FAHD1 | fumarylacetoacetate hydrolase domain containing 1 | 5.48104 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 | 5.42507 |
| C1ORF86 | chromosome 1 open reading frame 86 | 5.37077 |
| LBX2 | ladybird homeobox 2 | 5.22629 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | 5.21513 |
| TCTEX1D4 | Tctex1 domain containing 4 | 5.18062 |
| ADSSL1 | adenylosuccinate synthase like 1 | 5.16037 |
| ZACN | zinc activated ligand-gated ion channel | 5.13909 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 5.1354 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PNN | pinin, desmosome associated protein | -20.0 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -20.0 |
| CSNK1D | casein kinase 1, delta | -20.0 |
| LRRC41 | leucine rich repeat containing 41 | -20.0 |
| C12ORF73 | chromosome 12 open reading frame 73 | -20.0 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -20.0 |
| TRIM59 | tripartite motif containing 59 | -20.0 |
| EXOSC9 | exosome component 9 | -20.0 |
| POLG | polymerase (DNA directed), gamma | -20.0 |
| HPS3 | Hermansky-Pudlak syndrome 3 | -20.0 |
| SRFBP1 | serum response factor binding protein 1 | -20.0 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -20.0 |
| HEPACAM | hepatic and glial cell adhesion molecule | -20.0 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -20.0 |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 | -20.0 |
| APOB | apolipoprotein B | -20.0 |
| PEG10 | paternally expressed 10 | -19.0969 |
| ATP5E | ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit | -19.0969 |
| PRSS23 | protease, serine, 23 | -19.0 |
| FANCD2OS | FANCD2 opposite strand | -18.4949 |
| KIAA0895 | KIAA0895 | -17.8125 |
| GPS2 | G protein pathway suppressor 2 | -17.4949 |
| ZNF276 | zinc finger protein 276 | -17.4389 |
| ATP6V1C2 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 | -17.0259 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | -16.9551 |
| FAM149B1 | family with sequence similarity 149, member B1 | -16.8094 |
| CANX | calnexin | -16.3185 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -16.1877 |
| KLC1 | kinesin light chain 1 | -15.9465 |
| ERCC1 | excision repair cross-complementation group 1 | -15.5274 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -15.1483 |
| NT5DC4 | 5'-nucleotidase domain containing 4 | -15.0282 |
| BMP6 | bone morphogenetic protein 6 | -15.0193 |
| PMCH | pro-melanin-concentrating hormone | -14.454 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | -14.2286 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -13.7385 |
| PMEL | premelanosome protein | -13.6217 |
| EIF6 | eukaryotic translation initiation factor 6 | -13.4921 |
| LRRC59 | leucine rich repeat containing 59 | -13.351 |
| PHYKPL | 5-phosphohydroxy-L-lysine phospho-lyase | -13.1959 |
| C14ORF79 | chromosome 14 open reading frame 79 | -12.5552 |
| KIF7 | kinesin family member 7 | -12.5088 |
| PTMA | prothymosin, alpha | -12.2647 |
| CLCC1 | chloride channel CLIC-like 1 | -12.1178 |
| ENOSF1 | enolase superfamily member 1 | -12.0672 |
| RPL11 | ribosomal protein L11 | -11.7448 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -11.6899 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -11.6724 |
| LDHA | lactate dehydrogenase A | -11.5426 |
| MAX | MYC associated factor X | -11.512 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -11.4294 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -11.2582 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -10.8754 |
| LOC122455342 | testis-specific serine/proline-rich protein | -10.4745 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -10.4275 |
| SH3D19 | SH3 domain containing 19 | -10.4088 |
| PEG3 | paternally expressed 3 | -10.2863 |
| RUVBL1 | RuvB-like AAA ATPase 1 | -10.1443 |
| SRR | serine racemase | -10.102 |
| NCL | nucleolin | -10.079 |
| RMND5B | required for meiotic nuclear division 5 homolog B (S. cerevisiae) | -9.8503 |
| CCDC107 | coiled-coil domain containing 107 | -9.62878 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -9.62212 |
| ZBTB25 | zinc finger and BTB domain containing 25 | -9.51213 |
| RPL7 | ribosomal protein L7 | -9.37813 |
| SNX22 | sorting nexin 22 | -9.36025 |
| C19ORF54 | chromosome 19 open reading frame 54 | -9.26512 |
| SET | SET nuclear proto-oncogene | -9.23106 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -9.21067 |
| C6ORF89 | chromosome 6 open reading frame 89 | -9.13471 |
| ENO3 | enolase 3 (beta, muscle) | -9.07679 |
| NR2C2 | nuclear receptor subfamily 2, group C, member 2 | -8.98721 |
| COX20 | COX20 cytochrome c oxidase assembly factor | -8.93483 |
| NOSTRIN | nitric oxide synthase trafficking | -8.73216 |
| ADCY3 | adenylate cyclase 3 | -8.72484 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -8.44322 |
| ARHGEF39 | Rho guanine nucleotide exchange factor (GEF) 39 | -8.40343 |
| KAZN | kazrin, periplakin interacting protein | -8.38186 |
| GSE1 | Gse1 coiled-coil protein | -8.38186 |
| C11ORF58 | chromosome 11 open reading frame 58 | -8.36087 |
| CCL15 | chemokine (C-C motif) ligand 15 | -8.33648 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -8.31526 |
| PKM | pyruvate kinase, muscle | -8.24989 |
| TRIM14 | tripartite motif containing 14 | -8.24908 |
| RSPH9 | radial spoke head 9 homolog (Chlamydomonas) | -7.88743 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -7.83784 |
| DEK | DEK proto-oncogene | -7.83061 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase | -7.7739 |
| STAB1 | stabilin 1 | -7.53575 |
| DCLRE1C | DNA cross-link repair 1C | -7.27714 |
| LHFPL5 | lipoma HMGIC fusion partner-like 5 | -7.26587 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -7.26395 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -7.19607 |
| DNASE1 | deoxyribonuclease I | -7.1754 |
| PAQR4 | progestin and adipoQ receptor family member IV | -7.0975 |
| TPR | translocated promoter region, nuclear basket protein | -6.97358 |
| PTMS | parathymosin | -6.95561 |
| RPAIN | RPA interacting protein | -6.90321 |
| SUMO1 | small ubiquitin-like modifier 1 | -6.83258 |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 | -6.78301 |
