| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting CSL in HKC cell line (Study accession: SRP115628) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_8669_KD_CSL_SRP115628 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NPEPPS | aminopeptidase puromycin sensitive | 20.0 |
| MX1 | MX dynamin-like GTPase 1 | 20.0 |
| FERMT1 | fermitin family member 1 | 20.0 |
| TPM1 | tropomyosin 1 (alpha) | 20.0 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 20.0 |
| PCDH1 | protocadherin 1 | 20.0 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 20.0 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 20.0 |
| CTGF | connective tissue growth factor | 20.0 |
| LAMC2 | laminin, gamma 2 | 20.0 |
| TM4SF1 | transmembrane 4 L six family member 1 | 20.0 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 20.0 |
| HEPHL1 | hephaestin-like 1 | 20.0 |
| FN1 | fibronectin 1 | 20.0 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 20.0 |
| LOXL2 | lysyl oxidase-like 2 | 20.0 |
| HMGA2 | high mobility group AT-hook 2 | 20.0 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 20.0 |
| IFI27 | interferon, alpha-inducible protein 27 | 20.0 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 20.0 |
| MACC1 | metastasis associated in colon cancer 1 | 20.0 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 20.0 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 20.0 |
| TUFT1 | tuftelin 1 | 20.0 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 20.0 |
| SOX4 | SRY (sex determining region Y)-box 4 | 20.0 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 20.0 |
| SRPX | sushi-repeat containing protein, X-linked | 20.0 |
| IGF1R | insulin-like growth factor 1 receptor | 20.0 |
| DYSF | dysferlin | 20.0 |
| CCND1 | cyclin D1 | 20.0 |
| TSPAN1 | tetraspanin 1 | 20.0 |
| THBS1 | thrombospondin 1 | 20.0 |
| TAPBP | TAP binding protein (tapasin) | 20.0 |
| C1ORF74 | chromosome 1 open reading frame 74 | 20.0 |
| MCFD2 | multiple coagulation factor deficiency 2 | 20.0 |
| TMEM2 | transmembrane protein 2 | 20.0 |
| L1CAM | L1 cell adhesion molecule | 20.0 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 20.0 |
| INHBA | inhibin, beta A | 20.0 |
| COL4A1 | collagen, type IV, alpha 1 | 20.0 |
| PLAUR | plasminogen activator, urokinase receptor | 20.0 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 20.0 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 20.0 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 20.0 |
| CLDN1 | claudin 1 | 20.0 |
| CLDN4 | claudin 4 | 20.0 |
| IRF6 | interferon regulatory factor 6 | 20.0 |
| FOSL2 | FOS-like antigen 2 | 20.0 |
| GBP3 | guanylate binding protein 3 | 20.0 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 20.0 |
| ITGB6 | integrin, beta 6 | 20.0 |
| LRP1 | low density lipoprotein receptor-related protein 1 | 20.0 |
| IL1B | interleukin 1, beta | 20.0 |
| KRT6B | keratin 6B, type II | 20.0 |
| DSC2 | desmocollin 2 | 20.0 |
| SYNPO | synaptopodin | 20.0 |
| EMP1 | epithelial membrane protein 1 | 20.0 |
| TMSB4X | thymosin beta 4, X-linked | 20.0 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 20.0 |
| HSPG2 | heparan sulfate proteoglycan 2 | 20.0 |
| CTSC | cathepsin C | 20.0 |
| CD24 | CD24 molecule | 20.0 |
| LYPD3 | LY6/PLAUR domain containing 3 | 20.0 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 20.0 |
| IGF2R | insulin-like growth factor 2 receptor | 20.0 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | 20.0 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | 20.0 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 20.0 |
| MAP1B | microtubule-associated protein 1B | 20.0 |
| ADAM19 | ADAM metallopeptidase domain 19 | 20.0 |
| KRT34 | keratin 34, type I | 20.0 |
| NOTCH2 | notch 2 | 20.0 |
| TUBA1A | tubulin, alpha 1a | 20.0 |
| FAM222B | family with sequence similarity 222, member B | 20.0 |
| HEG1 | heart development protein with EGF-like domains 1 | 20.0 |
| FSTL1 | follistatin-like 1 | 20.0 |
| COL22A1 | collagen, type XXII, alpha 1 | 20.0 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 20.0 |
| CD82 | CD82 molecule | 20.0 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 | 20.0 |
| SVIL | supervillin | 20.0 |
| TGM2 | transglutaminase 2 | 20.0 |
| ANXA6 | annexin A6 | 20.0 |
| ANGPTL4 | angiopoietin-like 4 | 20.0 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) | 20.0 |
| MMP2 | matrix metallopeptidase 2 | 20.0 |
| MMP9 | matrix metallopeptidase 9 | 20.0 |
| MT1E | metallothionein 1E | 20.0 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 20.0 |
| PLAT | plasminogen activator, tissue | 20.0 |
| TMEM132A | transmembrane protein 132A | 20.0 |
| KRT7 | keratin 7, type II | 20.0 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | 20.0 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 20.0 |
| TMEM189 | transmembrane protein 189 | 20.0 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 20.0 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 20.0 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) | 20.0 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPAG5 | sperm associated antigen 5 | -20.0 |
| ADAMTSL1 | ADAMTS-like 1 | -20.0 |
| BIRC5 | baculoviral IAP repeat containing 5 | -20.0 |
| ARHGAP11A | Rho GTPase activating protein 11A | -20.0 |
| FANCD2 | Fanconi anemia, complementation group D2 | -20.0 |
| CDC45 | cell division cycle 45 | -20.0 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -20.0 |
| NME1 | NME/NM23 nucleoside diphosphate kinase 1 | -20.0 |
| CCNB2 | cyclin B2 | -20.0 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -20.0 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -20.0 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | -20.0 |
| KIF20A | kinesin family member 20A | -20.0 |
| SHCBP1 | SHC SH2-domain binding protein 1 | -20.0 |
| CEP55 | centrosomal protein 55kDa | -20.0 |
| CCDC113 | coiled-coil domain containing 113 | -20.0 |
| BRI3BP | BRI3 binding protein | -20.0 |
| GMNN | geminin, DNA replication inhibitor | -20.0 |
| KIF2C | kinesin family member 2C | -20.0 |
| BRCA1 | breast cancer 1, early onset | -20.0 |
| BRCA2 | breast cancer 2, early onset | -20.0 |
| KIF23 | kinesin family member 23 | -20.0 |
| PLK4 | polo-like kinase 4 | -20.0 |
| POLQ | polymerase (DNA directed), theta | -20.0 |
| KITLG | KIT ligand | -20.0 |
| EXO1 | exonuclease 1 | -20.0 |
| SH2B3 | SH2B adaptor protein 3 | -20.0 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | -20.0 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) | -20.0 |
| TRIP13 | thyroid hormone receptor interactor 13 | -20.0 |
| SMC2 | structural maintenance of chromosomes 2 | -20.0 |
| SPC24 | SPC24, NDC80 kinetochore complex component | -20.0 |
| HJURP | Holliday junction recognition protein | -20.0 |
| TTK | TTK protein kinase | -20.0 |
| NDC80 | NDC80 kinetochore complex component | -20.0 |
| WDR62 | WD repeat domain 62 | -20.0 |
| ORC1 | origin recognition complex, subunit 1 | -20.0 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | -20.0 |
| CENPA | centromere protein A | -20.0 |
| ASF1B | anti-silencing function 1B histone chaperone | -20.0 |
| FAM83D | family with sequence similarity 83, member D | -20.0 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -20.0 |
| ECT2 | epithelial cell transforming 2 | -20.0 |
| MCM10 | minichromosome maintenance complex component 10 | -20.0 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | -20.0 |
| CDC6 | cell division cycle 6 | -20.0 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | -20.0 |
| CDK1 | cyclin-dependent kinase 1 | -20.0 |
| GPATCH4 | G patch domain containing 4 | -20.0 |
| TONSL | tonsoku-like, DNA repair protein | -20.0 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | -20.0 |
| CDCA8 | cell division cycle associated 8 | -20.0 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -20.0 |
| MRPL10 | mitochondrial ribosomal protein L10 | -20.0 |
| CLSPN | claspin | -20.0 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -20.0 |
| FOXE1 | forkhead box E1 | -20.0 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -20.0 |
| DIAPH3 | diaphanous-related formin 3 | -20.0 |
| ATAD2 | ATPase family, AAA domain containing 2 | -20.0 |
| TMEM203 | transmembrane protein 203 | -20.0 |
| CDCA5 | cell division cycle associated 5 | -20.0 |
| CDCA7 | cell division cycle associated 7 | -20.0 |
| CDCA3 | cell division cycle associated 3 | -20.0 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -20.0 |
| FAM64A | family with sequence similarity 64, member A | -20.0 |
| SKA1 | spindle and kinetochore associated complex subunit 1 | -20.0 |
| SKA3 | spindle and kinetochore associated complex subunit 3 | -20.0 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) | -20.0 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -20.0 |
| TYMS | thymidylate synthetase | -20.0 |
| KNTC1 | kinetochore associated 1 | -20.0 |
| FAM111B | family with sequence similarity 111, member B | -20.0 |
| CDCA2 | cell division cycle associated 2 | -20.0 |
| FEN1 | flap structure-specific endonuclease 1 | -20.0 |
| TROAP | trophinin associated protein | -20.0 |
| NCAPG | non-SMC condensin I complex, subunit G | -20.0 |
| KIF18B | kinesin family member 18B | -20.0 |
| ERCC6L | excision repair cross-complementation group 6-like | -20.0 |
| CKAP2L | cytoskeleton associated protein 2-like | -20.0 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -20.0 |
| KIF14 | kinesin family member 14 | -20.0 |
| KIF11 | kinesin family member 11 | -20.0 |
| RHOG | ras homolog family member G | -20.0 |
| CENPH | centromere protein H | -20.0 |
| CENPW | centromere protein W | -20.0 |
| NCAPH | non-SMC condensin I complex, subunit H | -20.0 |
| TFAM | transcription factor A, mitochondrial | -20.0 |
| NUF2 | NUF2, NDC80 kinetochore complex component | -20.0 |
| PBK | PDZ binding kinase | -20.0 |
| CASC5 | cancer susceptibility candidate 5 | -20.0 |
| GTSE1 | G-2 and S-phase expressed 1 | -20.0 |
| ZNF367 | zinc finger protein 367 | -20.0 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -20.0 |
| WDHD1 | WD repeat and HMG-box DNA binding protein 1 | -20.0 |
| AURKB | aurora kinase B | -20.0 |
| KIF4A | kinesin family member 4A | -20.0 |
| WDR76 | WD repeat domain 76 | -20.0 |
| ZWINT | ZW10 interacting kinetochore protein | -20.0 |
| MELK | maternal embryonic leucine zipper kinase | -20.0 |
