| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting HERV in HSF cell line were purchased from CTCC cell line (Study accession: SRP343980) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_8731_KD_HERV_SRP343980 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRSS23 | protease, serine, 23 | 20.0 |
| TPM3 | tropomyosin 3 | 20.0 |
| UBE2Z | ubiquitin-conjugating enzyme E2Z | 20.0 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 20.0 |
| TFPI2 | tissue factor pathway inhibitor 2 | 20.0 |
| CCL5 | chemokine (C-C motif) ligand 5 | 20.0 |
| SCARB2 | scavenger receptor class B, member 2 | 20.0 |
| LIMA1 | LIM domain and actin binding 1 | 20.0 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 20.0 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 20.0 |
| CD164 | CD164 molecule, sialomucin | 20.0 |
| TPM4 | tropomyosin 4 | 20.0 |
| ALCAM | activated leukocyte cell adhesion molecule | 20.0 |
| GANAB | glucosidase, alpha; neutral AB | 20.0 |
| GRN | granulin | 20.0 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 20.0 |
| MYO10 | myosin X | 20.0 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 20.0 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 20.0 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 20.0 |
| IFI6 | interferon, alpha-inducible protein 6 | 20.0 |
| MX2 | MX dynamin-like GTPase 2 | 20.0 |
| MX1 | MX dynamin-like GTPase 1 | 20.0 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 20.0 |
| IFITM3 | interferon induced transmembrane protein 3 | 20.0 |
| RNF213 | ring finger protein 213 | 20.0 |
| RRBP1 | ribosome binding protein 1 | 20.0 |
| TRIP12 | thyroid hormone receptor interactor 12 | 20.0 |
| SAMD9L | sterile alpha motif domain containing 9-like | 20.0 |
| LY6E | lymphocyte antigen 6 complex, locus E | 20.0 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase | 20.0 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 20.0 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 20.0 |
| GBP4 | guanylate binding protein 4 | 20.0 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 20.0 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | 20.0 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 20.0 |
| ADAR | adenosine deaminase, RNA-specific | 20.0 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 20.0 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 20.0 |
| LDHA | lactate dehydrogenase A | 20.0 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 20.0 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 20.0 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 20.0 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 20.0 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 20.0 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 20.0 |
| ISG15 | ISG15 ubiquitin-like modifier | 20.0 |
| CD44 | CD44 molecule (Indian blood group) | 20.0 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 20.0 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 20.0 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | 20.0 |
| HM13 | histocompatibility (minor) 13 | 20.0 |
| CKAP4 | cytoskeleton-associated protein 4 | 20.0 |
| ITM2B | integral membrane protein 2B | 20.0 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 20.0 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 20.0 |
| MT2A | metallothionein 2A | 20.0 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 20.0 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 20.0 |
| B2M | beta-2-microglobulin | 20.0 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 20.0 |
| SFRP1 | secreted frizzled-related protein 1 | 20.0 |
| SAMD9 | sterile alpha motif domain containing 9 | 20.0 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 20.0 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 20.0 |
| MCL1 | myeloid cell leukemia 1 | 20.0 |
| ADAM19 | ADAM metallopeptidase domain 19 | 20.0 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 20.0 |
| OPTN | optineurin | 20.0 |
| HLA-B | major histocompatibility complex, class I, B | 20.0 |
| HLA-A | major histocompatibility complex, class I, A | 20.0 |
| LGMN | legumain | 20.0 |
| CTSL | cathepsin L | 20.0 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 20.0 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 20.0 |
| HLA-C | major histocompatibility complex, class I, C | 20.0 |
| HLA-E | major histocompatibility complex, class I, E | 20.0 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 20.0 |
| WARS | tryptophanyl-tRNA synthetase | 20.0 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 20.0 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 20.0 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 20.0 |
| ANPEP | alanyl (membrane) aminopeptidase | 20.0 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 20.0 |
| SLFN5 | schlafen family member 5 | 20.0 |
| IFI16 | interferon, gamma-inducible protein 16 | 20.0 |
| TRIM22 | tripartite motif containing 22 | 20.0 |
| TMSB10 | thymosin beta 10 | 20.0 |
| TXNIP | thioredoxin interacting protein | 20.0 |
| CLIC4 | chloride intracellular channel 4 | 20.0 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 20.0 |
| H3F3A | H3 histone, family 3A | 20.0 |
| SULF1 | sulfatase 1 | 20.0 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 20.0 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 20.0 |
| ECE1 | endothelin converting enzyme 1 | 20.0 |
| PRNP | prion protein | 20.0 |
| IFIH1 | interferon induced with helicase C domain 1 | 20.0 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| C16ORF45 | chromosome 16 open reading frame 45 | -20.0 |
| NUDT16L1 | nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 | -20.0 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 | -20.0 |
| GLIS3 | GLIS family zinc finger 3 | -20.0 |
| KCNIP3 | Kv channel interacting protein 3, calsenilin | -20.0 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -20.0 |
| ANKRD34A | ankyrin repeat domain 34A | -20.0 |
| CC2D2A | coiled-coil and C2 domain containing 2A | -20.0 |
| DIRAS1 | DIRAS family, GTP-binding RAS-like 1 | -20.0 |
| CNN1 | calponin 1, basic, smooth muscle | -20.0 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | -20.0 |
| TMEM35 | transmembrane protein 35 | -20.0 |
| CDK15 | cyclin-dependent kinase 15 | -20.0 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | -20.0 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | -20.0 |
| RHOD | ras homolog family member D | -20.0 |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa | -20.0 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 | -20.0 |
| SLC38A4 | solute carrier family 38, member 4 | -20.0 |
| SH3GL2 | SH3-domain GRB2-like 2 | -20.0 |
| CLCN5 | chloride channel, voltage-sensitive 5 | -20.0 |
| CHML | choroideremia-like (Rab escort protein 2) | -20.0 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | -20.0 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -20.0 |
| PITPNM3 | PITPNM family member 3 | -20.0 |
| TMEM120B | transmembrane protein 120B | -20.0 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 | -20.0 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -20.0 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -20.0 |
| SOCS7 | suppressor of cytokine signaling 7 | -20.0 |
| PNPLA3 | patatin-like phospholipase domain containing 3 | -20.0 |
| DPY19L3 | dpy-19-like 3 (C. elegans) | -20.0 |
| LOC728392 | uncharacterized LOC728392 | -20.0 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -20.0 |
| JADE1 | jade family PHD finger 1 | -20.0 |
| OTUD3 | OTU deubiquitinase 3 | -20.0 |
| HMCN1 | hemicentin 1 | -20.0 |
| ZSWIM7 | zinc finger, SWIM-type containing 7 | -20.0 |
| GCAT | glycine C-acetyltransferase | -20.0 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -20.0 |
| MAP3K7CL | MAP3K7 C-terminal like | -20.0 |
| RASL10B | RAS-like, family 10, member B | -20.0 |
| PLEKHG4 | pleckstrin homology domain containing, family G (with RhoGef domain) member 4 | -20.0 |
| AKAP6 | A kinase (PRKA) anchor protein 6 | -20.0 |
| ANOS1 | anosmin 1 | -20.0 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | -20.0 |
| STAC | SH3 and cysteine rich domain | -20.0 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | -20.0 |
| RHOBTB1 | Rho-related BTB domain containing 1 | -20.0 |
| SLC7A14 | solute carrier family 7, member 14 | -20.0 |
| FAM212B | family with sequence similarity 212, member B | -20.0 |
| GATSL2 | GATS protein-like 2 | -20.0 |
| SLC38A2 | solute carrier family 38, member 2 | -20.0 |
| PYGO1 | pygopus family PHD finger 1 | -20.0 |
| GSTA4 | glutathione S-transferase alpha 4 | -20.0 |
| PLA2G12A | phospholipase A2, group XIIA | -20.0 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -20.0 |
| ARL3 | ADP-ribosylation factor-like 3 | -20.0 |
| PIDD1 | p53-induced death domain protein 1 | -20.0 |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 | -20.0 |
| TMEM178B | transmembrane protein 178B | -20.0 |
| FAT3 | FAT atypical cadherin 3 | -20.0 |
| RGS5 | regulator of G-protein signaling 5 | -20.0 |
| CSDC2 | cold shock domain containing C2, RNA binding | -20.0 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -20.0 |
| TMEM168 | transmembrane protein 168 | -20.0 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | -20.0 |
| KRTAP1-5 | keratin associated protein 1-5 | -20.0 |
| CEND1 | cell cycle exit and neuronal differentiation 1 | -20.0 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 | -20.0 |
| FAM172A | family with sequence similarity 172, member A | -20.0 |
| IGIP | IgA-inducing protein | -20.0 |
| SNRPD3 | small nuclear ribonucleoprotein D3 polypeptide 18kDa | -20.0 |
| HSPA4L | heat shock 70kDa protein 4-like | -20.0 |
| LMOD1 | leiomodin 1 (smooth muscle) | -20.0 |
| PCDHGA7 | protocadherin gamma subfamily A, 7 | -20.0 |
| FITM2 | fat storage-inducing transmembrane protein 2 | -20.0 |
| ARMCX4 | armadillo repeat containing, X-linked 4 | -20.0 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | -20.0 |
| REEP2 | receptor accessory protein 2 | -20.0 |
| SYTL5 | synaptotagmin-like 5 | -20.0 |
| GPATCH11 | G patch domain containing 11 | -20.0 |
| KCTD7 | potassium channel tetramerization domain containing 7 | -20.0 |
| TNS2 | tensin 2 | -20.0 |
| WRB | tryptophan rich basic protein | -20.0 |
| TMEM8B | transmembrane protein 8B | -20.0 |
| CEP78 | centrosomal protein 78kDa | -20.0 |
| NAP1L3 | nucleosome assembly protein 1-like 3 | -20.0 |
| KIAA1462 | KIAA1462 | -20.0 |
| NREP | neuronal regeneration related protein | -20.0 |
| NMT2 | N-myristoyltransferase 2 | -20.0 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 | -20.0 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -20.0 |
| SYNC | syncoilin, intermediate filament protein | -20.0 |
| RAB40B | RAB40B, member RAS oncogene family | -20.0 |
| NOV | nephroblastoma overexpressed | -20.0 |
| FNDC4 | fibronectin type III domain containing 4 | -20.0 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 | -20.0 |
| HSPB3 | heat shock 27kDa protein 3 | -20.0 |
| ARL4C | ADP-ribosylation factor-like 4C | -20.0 |