Perturb_8854_OE_ERG3_SRP034736 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description OE perturbation targeting ERG3 in Human cord blood derived CD34+ cells cell (Study accession: SRP034736) (PerturbAtlas)
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Genes

200 genes differentially expressed following the Perturb_8854_OE_ERG3_SRP034736 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
CD36 CD36 molecule (thrombospondin receptor) 20.0
OGFRL1 opioid growth factor receptor-like 1 20.0
MGAM maltase-glucoamylase 20.0
BIN1 bridging integrator 1 20.0
CD1C CD1c molecule 20.0
STAB1 stabilin 1 20.0
ZNF467 zinc finger protein 467 20.0
TM4SF1 transmembrane 4 L six family member 1 20.0
PALD1 phosphatase domain containing, paladin 1 20.0
CLEC5A C-type lectin domain family 5, member A 20.0
LPAR6 lysophosphatidic acid receptor 6 20.0
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 20.0
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 20.0
PTK2 protein tyrosine kinase 2 20.0
CD34 CD34 molecule 20.0
PADI4 peptidyl arginine deiminase, type IV 20.0
GPR171 G protein-coupled receptor 171 20.0
FGD4 FYVE, RhoGEF and PH domain containing 4 20.0
HEG1 heart development protein with EGF-like domains 1 20.0
FHDC1 FH2 domain containing 1 20.0
SH3BP2 SH3-domain binding protein 2 20.0
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 20.0
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 20.0
NAV1 neuron navigator 1 20.0
IRF4 interferon regulatory factor 4 20.0
A2M alpha-2-macroglobulin 20.0
KCTD12 potassium channel tetramerization domain containing 12 20.0
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 20.0
DUSP27 dual specificity phosphatase 27 (putative) 20.0
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 20.0
TMSB4X thymosin beta 4, X-linked 20.0
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 20.0
IL10RA interleukin 10 receptor, alpha 19.699
MMP24 matrix metallopeptidase 24 (membrane-inserted) 19.699
LOXL3 lysyl oxidase-like 3 19.699
PXN paxillin 19.699
CSF3R colony stimulating factor 3 receptor (granulocyte) 19.699
IPCEF1 interaction protein for cytohesin exchange factors 1 19.3979
DYSF dysferlin 18.5686
BHLHE41 basic helix-loop-helix family, member e41 18.5528
GRN granulin 18.4815
FMNL3 formin-like 3 18.3279
MARCKS myristoylated alanine-rich protein kinase C substrate 18.1871
CSF1R colony stimulating factor 1 receptor 17.2321
MEF2C myocyte enhancer factor 2C 17.158
C10ORF128 chromosome 10 open reading frame 128 16.9914
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1 16.4154
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 16.1591
PLVAP plasmalemma vesicle associated protein 16.0761
SHANK3 SH3 and multiple ankyrin repeat domains 3 15.8637
SCARF1 scavenger receptor class F, member 1 15.8468
MAPK11 mitogen-activated protein kinase 11 15.5648
PTPN1 protein tyrosine phosphatase, non-receptor type 1 15.5487
TESC tescalcin 15.4845
CSRP2 cysteine and glycine-rich protein 2 15.3226
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 15.2341
LGMN legumain 15.2178
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 15.0989
DENND3 DENN/MADD domain containing 3 15.0839
FAM19A2 family with sequence similarity 19 (chemokine (C-C motif)-like), member A2 15.0429
SGK1 serum/glucocorticoid regulated kinase 1 15.0429
ACE angiotensin I converting enzyme 14.8004
ZCCHC24 zinc finger, CCHC domain containing 24 14.8004
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase 14.5734
ANPEP alanyl (membrane) aminopeptidase 14.5682
NABP1 nucleic acid binding protein 1 14.5337
NELL1 NEL-like 1 (chicken) 14.4579
CD1E CD1e molecule 14.2877
LRRK2 leucine-rich repeat kinase 2 14.2692
BCAR3 breast cancer anti-estrogen resistance 3 14.0185
FERMT3 fermitin family member 3 13.9125
IDO1 indoleamine 2,3-dioxygenase 1 13.7823
IL13RA1 interleukin 13 receptor, alpha 1 13.7357
SIGLEC9 sialic acid binding Ig-like lectin 9 13.7114
LAMP3 lysosomal-associated membrane protein 3 13.5213
STARD8 StAR-related lipid transfer (START) domain containing 8 13.4788
ZFP36 ZFP36 ring finger protein 13.3716
THEMIS2 thymocyte selection associated family member 2 13.1633
CD300A CD300a molecule 12.8439
FSCN1 fascin actin-bundling protein 1 12.6435
FAM129B family with sequence similarity 129, member B 12.5981
C20ORF27 chromosome 20 open reading frame 27 12.456
MEF2A myocyte enhancer factor 2A 12.4247
CCL22 chemokine (C-C motif) ligand 22 12.3403
CD200 CD200 molecule 12.2872
RGS18 regulator of G-protein signaling 18 12.0321
MPZL3 myelin protein zero-like 3 12.0192
ALOX12 arachidonate 12-lipoxygenase 12.0084
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 11.9189
GNPDA1 glucosamine-6-phosphate deaminase 1 11.6621
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 11.6079
CREB5 cAMP responsive element binding protein 5 11.5545
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 11.5239
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 11.3783
KIAA1462 KIAA1462 11.3213
RGL1 ral guanine nucleotide dissociation stimulator-like 1 11.2299
SCN1B sodium channel, voltage gated, type I beta subunit 11.1857
KANK2 KN motif and ankyrin repeat domains 2 11.1401
HLA-DMB major histocompatibility complex, class II, DM beta 11.1207
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 11.0767

decreased expression

Symbol Name Standardized Value
TOP1MT topoisomerase (DNA) I, mitochondrial -20.0
APLP2 amyloid beta (A4) precursor-like protein 2 -20.0
CA8 carbonic anhydrase VIII -20.0
PRTN3 proteinase 3 -20.0
MMP2 matrix metallopeptidase 2 -20.0
ASB1 ankyrin repeat and SOCS box containing 1 -20.0
IGLL1 immunoglobulin lambda-like polypeptide 1 -19.5229
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10 -18.9586
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1 -17.6198
CALR calreticulin -17.399
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1 -17.2055
PRSS57 protease, serine, 57 -15.8637
NUCB2 nucleobindin 2 -15.5339
B3GNT7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 -14.1315
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -14.0661
NYNRIN NYN domain and retroviral integrase containing -12.456
RNF144A ring finger protein 144A -12.2644
RFX8 RFX family member 8, lacking RFX DNA binding domain -12.262
IGFBP7 insulin-like growth factor binding protein 7 -11.6458
NOG noggin -11.1641
P4HB prolyl 4-hydroxylase, beta polypeptide -11.0483
MAGED1 melanoma antigen family D1 -11.0049
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -10.9799
LGALS13 lectin, galactoside-binding, soluble, 13 -10.9116
GLUL glutamate-ammonia ligase -10.8848
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 -10.746
CPXM1 carboxypeptidase X (M14 family), member 1 -10.2176
FBLN1 fibulin 1 -10.2031
FAM117A family with sequence similarity 117, member A -9.56406
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -9.55542
FAM107B family with sequence similarity 107, member B -9.26616
DENND1C DENN/MADD domain containing 1C -9.17057
TRO trophinin -9.14474
MYB v-myb avian myeloblastosis viral oncogene homolog -9.07609
HSH2D hematopoietic SH2 domain containing -8.89959
REC8 REC8 meiotic recombination protein -8.68492
MAP1A microtubule-associated protein 1A -8.68233
DUSP4 dual specificity phosphatase 4 -8.6684
CERCAM cerebral endothelial cell adhesion molecule -8.46126
RPL22L1 ribosomal protein L22-like 1 -8.34773
OCIAD2 OCIA domain containing 2 -8.18285
SLFN11 schlafen family member 11 -8.13118
CAPG capping protein (actin filament), gelsolin-like -8.12963
NT5DC2 5'-nucleotidase domain containing 2 -8.07673
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -7.68209
TDRD7 tudor domain containing 7 -7.65434
GAPT GRB2-binding adaptor protein, transmembrane -7.61874
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -7.58157
MFAP4 microfibrillar-associated protein 4 -7.40433
ADA adenosine deaminase -7.35463
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 -7.31172
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 -7.2886
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) -7.26073
C1QTNF4 C1q and tumor necrosis factor related protein 4 -7.10835
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C -7.08263
CTSG cathepsin G -7.01004
USP11 ubiquitin specific peptidase 11 -6.99723
CHRDL1 chordin-like 1 -6.88978
ZBTB16 zinc finger and BTB domain containing 16 -6.7522
LIMD2 LIM domain containing 2 -6.67452
HYOU1 hypoxia up-regulated 1 -6.64646
LPO lactoperoxidase -6.599
MYC v-myc avian myelocytomatosis viral oncogene homolog -6.58596
MCM3AP minichromosome maintenance complex component 3 associated protein -6.46242
GRAMD4 GRAM domain containing 4 -6.40539
STMN3 stathmin-like 3 -6.29471
OBSL1 obscurin-like 1 -6.22593
PPP1R26 protein phosphatase 1, regulatory subunit 26 -6.1725
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 -6.10555
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -6.03368
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF -5.93467
PHGDH phosphoglycerate dehydrogenase -5.90921
CHST13 carbohydrate (chondroitin 4) sulfotransferase 13 -5.89569
BCL2 B-cell CLL/lymphoma 2 -5.89125
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 -5.82607
CCNA1 cyclin A1 -5.78895
TRMT6 tRNA methyltransferase 6 -5.78895
AEBP1 AE binding protein 1 -5.68484
GRIK5 glutamate receptor, ionotropic, kainate 5 -5.6671
HAL histidine ammonia-lyase -5.62516
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 -5.56993
DAP death-associated protein -5.56311
PLAU plasminogen activator, urokinase -5.46814
ACSM3 acyl-CoA synthetase medium-chain family member 3 -5.41069
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing -5.40017
TATDN1 TatD DNase domain containing 1 -5.39098
MYO1G myosin IG -5.33515
ISYNA1 inositol-3-phosphate synthase 1 -5.22476
RHOBTB1 Rho-related BTB domain containing 1 -5.22455
IKZF1 IKAROS family zinc finger 1 (Ikaros) -5.20156
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 -5.18567
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -5.15493
DTX4 deltex 4, E3 ubiquitin ligase -5.11524
NEU3 sialidase 3 (membrane sialidase) -5.075
XYLT1 xylosyltransferase I -5.07149
AK5 adenylate kinase 5 -5.06757
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 -5.05372
ABLIM1 actin binding LIM protein 1 -5.05051
SOX4 SRY (sex determining region Y)-box 4 -5.04178
NAT14 N-acetyltransferase 14 (GCN5-related, putative) -5.01685