| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting CCDC144NLAS1 in human embryonic stem cells H14 cell line (Study accession: SRP135858) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_8908_KD_CCDC144NLAS1_SRP135858 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DUSP5 | dual specificity phosphatase 5 | 20.0 |
| B3GNT7 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 | 20.0 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | 20.0 |
| ETV5 | ets variant 5 | 20.0 |
| GRM4 | glutamate receptor, metabotropic 4 | 20.0 |
| THY1 | Thy-1 cell surface antigen | 20.0 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 | 20.0 |
| HAS2 | hyaluronan synthase 2 | 20.0 |
| MT1G | metallothionein 1G | 20.0 |
| MT1H | metallothionein 1H | 20.0 |
| AK4 | adenylate kinase 4 | 20.0 |
| HMOX1 | heme oxygenase 1 | 20.0 |
| ARRDC3 | arrestin domain containing 3 | 20.0 |
| KAT7 | K(lysine) acetyltransferase 7 | 20.0 |
| KDR | kinase insert domain receptor | 20.0 |
| GDF15 | growth differentiation factor 15 | 20.0 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 20.0 |
| FOSL1 | FOS-like antigen 1 | 20.0 |
| ZNF90 | zinc finger protein 90 | 20.0 |
| SOX4 | SRY (sex determining region Y)-box 4 | 20.0 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 20.0 |
| EPS8L2 | EPS8-like 2 | 20.0 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 20.0 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | 20.0 |
| TMEM63A | transmembrane protein 63A | 20.0 |
| EDNRB | endothelin receptor type B | 20.0 |
| RND3 | Rho family GTPase 3 | 20.0 |
| MCL1 | myeloid cell leukemia 1 | 20.0 |
| CTCFL | CCCTC-binding factor (zinc finger protein)-like | 20.0 |
| NANOG | Nanog homeobox | 20.0 |
| CLIC1 | chloride intracellular channel 1 | 20.0 |
| SKIL | SKI-like proto-oncogene | 20.0 |
| COL1A2 | collagen, type I, alpha 2 | 20.0 |
| SHISA2 | shisa family member 2 | 19.5229 |
| B3GALT5 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 | 19.3979 |
| GDF3 | growth differentiation factor 3 | 19.3979 |
| GRPR | gastrin-releasing peptide receptor | 18.6778 |
| IL17RD | interleukin 17 receptor D | 18.0458 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 | 17.9031 |
| FAM102B | family with sequence similarity 102, member B | 17.8508 |
| FBLIM1 | filamin binding LIM protein 1 | 17.3468 |
| TRIB2 | tribbles pseudokinase 2 | 16.6657 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 16.4755 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 16.2838 |
| CBR1 | carbonyl reductase 1 | 16.2756 |
| MCAM | melanoma cell adhesion molecule | 15.8758 |
| PXN | paxillin | 15.7972 |
| JADE1 | jade family PHD finger 1 | 15.397 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 15.2781 |
| WFDC2 | WAP four-disulfide core domain 2 | 14.9601 |
| PGPEP1 | pyroglutamyl-peptidase I | 14.9196 |
| VENTX | VENT homeobox | 14.8927 |
| COL14A1 | collagen, type XIV, alpha 1 | 14.8154 |
| ADD2 | adducin 2 (beta) | 14.8005 |
| FDXR | ferredoxin reductase | 14.7667 |
| DPPA4 | developmental pluripotency associated 4 | 14.4221 |
| DLL3 | delta-like 3 (Drosophila) | 14.312 |
| RMND5B | required for meiotic nuclear division 5 homolog B (S. cerevisiae) | 14.2434 |
| FAM171B | family with sequence similarity 171, member B | 14.2 |
| MKRN1 | makorin ring finger protein 1 | 14.0595 |
| CORO2A | coronin, actin binding protein, 2A | 13.5349 |
| ITPKB | inositol-trisphosphate 3-kinase B | 13.4997 |
| NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1 | 13.4172 |
| APP | amyloid beta (A4) precursor protein | 12.9528 |
| HSPA1B | heat shock 70kDa protein 1B | 12.9323 |
| FN1 | fibronectin 1 | 12.6883 |
| GOLGA4 | golgin A4 | 12.6244 |
| METTL7A | methyltransferase like 7A | 12.6063 |
| PGM1 | phosphoglucomutase 1 | 12.3946 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 12.2682 |
| TRIML2 | tripartite motif family-like 2 | 12.1991 |
| BTG2 | BTG family, member 2 | 12.17 |
| WDR60 | WD repeat domain 60 | 12.1386 |
| GAL | galanin/GMAP prepropeptide | 12.0379 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | 11.6931 |
| ZNF770 | zinc finger protein 770 | 11.6463 |
| NANOGP8 | Nanog homeobox pseudogene 8 | 11.6144 |
| GSTT2B | glutathione S-transferase theta 2B (gene/pseudogene) | 11.5933 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 11.3867 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 11.2878 |
| SULF1 | sulfatase 1 | 11.2794 |
| MAT2B | methionine adenosyltransferase II, beta | 11.2059 |
| DPPA2 | developmental pluripotency associated 2 | 11.1587 |
| CARD11 | caspase recruitment domain family, member 11 | 11.0508 |
| SFN | stratifin | 11.0508 |
| ETV1 | ets variant 1 | 11.0508 |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 11.0386 |
| ARF4 | ADP-ribosylation factor 4 | 10.9246 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 10.608 |
| ODC1 | ornithine decarboxylase 1 | 10.5832 |
| ARRDC4 | arrestin domain containing 4 | 10.5362 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 10.4801 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 10.4693 |
| SQSTM1 | sequestosome 1 | 10.4088 |
| PTEN | phosphatase and tensin homolog | 10.4031 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 | 10.1396 |
| HAS3 | hyaluronan synthase 3 | 10.1396 |
| RBM38 | RNA binding motif protein 38 | 10.1212 |
| ESYT2 | extended synaptotagmin-like protein 2 | 9.98367 |
| CDCA7L | cell division cycle associated 7-like | 9.94081 |
| Symbol | Name | Standardized Value |
|---|---|---|
| C6ORF141 | chromosome 6 open reading frame 141 | -20.0 |
| ALCAM | activated leukocyte cell adhesion molecule | -20.0 |
| TPM1 | tropomyosin 1 (alpha) | -20.0 |
| ATF4 | activating transcription factor 4 | -20.0 |
| FGFR1 | fibroblast growth factor receptor 1 | -20.0 |
| CHGA | chromogranin A | -20.0 |
| RAB17 | RAB17, member RAS oncogene family | -20.0 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | -20.0 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | -20.0 |
| C1ORF21 | chromosome 1 open reading frame 21 | -20.0 |
| CA11 | carbonic anhydrase XI | -20.0 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | -20.0 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | -20.0 |
| FLT1 | fms-related tyrosine kinase 1 | -20.0 |
| ABRACL | ABRA C-terminal like | -20.0 |
| ASS1 | argininosuccinate synthase 1 | -20.0 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -20.0 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 | -20.0 |
| RRP1B | ribosomal RNA processing 1B | -20.0 |
| ADM | adrenomedullin | -20.0 |
| SKIDA1 | SKI/DACH domain containing 1 | -20.0 |
| TEK | TEK tyrosine kinase, endothelial | -20.0 |
| SMIM10L2A | small integral membrane protein 10 like 2A | -20.0 |
| PODXL | podocalyxin-like | -20.0 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -20.0 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -20.0 |
| METAP2 | methionyl aminopeptidase 2 | -20.0 |
| VAT1L | vesicle amine transport 1-like | -20.0 |
| DHFR | dihydrofolate reductase | -20.0 |
| ZIC3 | Zic family member 3 | -20.0 |
| HMCN2 | hemicentin 2 | -20.0 |
| AJUBA | ajuba LIM protein | -20.0 |
| PKDCC | protein kinase domain containing, cytoplasmic | -20.0 |
| SOX3 | SRY (sex determining region Y)-box 3 | -20.0 |
| SLFN13 | schlafen family member 13 | -20.0 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -20.0 |
| ANOS1 | anosmin 1 | -20.0 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -20.0 |
| AHNAK | AHNAK nucleoprotein | -20.0 |
| SESN3 | sestrin 3 | -20.0 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -20.0 |
| SFRP1 | secreted frizzled-related protein 1 | -20.0 |
| AUTS2 | autism susceptibility candidate 2 | -20.0 |
| DCLK1 | doublecortin-like kinase 1 | -20.0 |
| OLFML3 | olfactomedin-like 3 | -20.0 |
| TMEM64 | transmembrane protein 64 | -20.0 |
| APELA | apelin receptor early endogenous ligand | -20.0 |
| TP53I11 | tumor protein p53 inducible protein 11 | -20.0 |
| OBSL1 | obscurin-like 1 | -20.0 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -20.0 |
| RHBDL3 | rhomboid, veinlet-like 3 (Drosophila) | -20.0 |
| PLCL2 | phospholipase C-like 2 | -20.0 |
| GDPD2 | glycerophosphodiester phosphodiesterase domain containing 2 | -20.0 |
| RGS5 | regulator of G-protein signaling 5 | -20.0 |
| GPC4 | glypican 4 | -20.0 |
| GPC3 | glypican 3 | -20.0 |
| DIAPH2 | diaphanous-related formin 2 | -20.0 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -20.0 |
| CRABP2 | cellular retinoic acid binding protein 2 | -20.0 |
| FZD7 | frizzled class receptor 7 | -20.0 |
| FZD2 | frizzled class receptor 2 | -20.0 |
| SLC7A3 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 | -20.0 |
| NAV2 | neuron navigator 2 | -20.0 |
| GPR176 | G protein-coupled receptor 176 | -20.0 |
| FAM3C | family with sequence similarity 3, member C | -20.0 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -20.0 |
| OTX2 | orthodenticle homeobox 2 | -20.0 |
| LITAF | lipopolysaccharide-induced TNF factor | -19.699 |
| FGFR3 | fibroblast growth factor receptor 3 | -19.5229 |
| TTYH1 | tweety family member 1 | -19.5229 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -19.0969 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | -18.8539 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa | -18.7696 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -18.7696 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -18.7447 |
| CNTNAP2 | contactin associated protein-like 2 | -18.6021 |
| PPP1R3B | protein phosphatase 1, regulatory subunit 3B | -18.5528 |
| GLUL | glutamate-ammonia ligase | -18.3565 |
| AMOTL2 | angiomotin like 2 | -18.1367 |
| ARHGAP23 | Rho GTPase activating protein 23 | -17.767 |
| CCNA2 | cyclin A2 | -17.6198 |
| COL5A2 | collagen, type V, alpha 2 | -17.4737 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -17.1662 |
| LARP7 | La ribonucleoprotein domain family, member 7 | -17.1163 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -17.0706 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -17.055 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | -17.0292 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 | -16.8684 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | -16.7964 |
| CADM4 | cell adhesion molecule 4 | -16.7755 |
| GAS6 | growth arrest-specific 6 | -16.634 |
| CACHD1 | cache domain containing 1 | -16.3938 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -16.3373 |
| ARL4C | ADP-ribosylation factor-like 4C | -16.0062 |
| GSN | gelsolin | -15.8716 |
| TRIM2 | tripartite motif containing 2 | -15.8538 |
| BLACAT1 | bladder cancer associated transcript 1 (non-protein coding) | -15.7001 |
| DAZL | deleted in azoospermia-like | -15.6328 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -15.6238 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | -15.6038 |