Perturb_8932_KD_OAS2_SRP345622 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting OAS2 in human epidermal keratinocytes cell (Study accession: SRP345622) (PerturbAtlas)
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Genes

43 genes differentially expressed following the Perturb_8932_KD_OAS2_SRP345622 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
IL6R interleukin 6 receptor 4.55532
INHBA inhibin, beta A 3.6236
CBX1 chromobox homolog 1 3.6236
MAPRE1 microtubule-associated protein, RP/EB family, member 1 3.57812
SPRR2A small proline-rich protein 2A 3.57812
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 3.57812
LGALSL lectin, galactoside-binding-like 3.3144
HIPK3 homeodomain interacting protein kinase 3 2.52687
C1QTNF1 C1q and tumor necrosis factor related protein 1 2.37253
LMBRD1 LMBR1 domain containing 1 2.26023
MMD monocyte to macrophage differentiation-associated 2.07767
GADD45A growth arrest and DNA-damage-inducible, alpha 2.0717
RNF7 ring finger protein 7 2.02238
SPRR1B small proline-rich protein 1B 1.9064
IL36RN interleukin 36 receptor antagonist 1.81867
ZMAT3 zinc finger, matrin-type 3 1.81867
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.64395
ELOVL7 ELOVL fatty acid elongase 7 1.61424
DBT dihydrolipoamide branched chain transacylase E2 1.61424
MTSS1 metastasis suppressor 1 1.61424
SPOPL speckle-type POZ protein-like 1.50724
HINT3 histidine triad nucleotide binding protein 3 1.40817
TMEM254 transmembrane protein 254 1.3364
SDCBP2 syndecan binding protein (syntenin) 2 1.31742
BIRC3 baculoviral IAP repeat containing 3 1.31742

decreased expression

Symbol Name Standardized Value
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 -12.7703
FAM20B family with sequence similarity 20, member B -5.92452
NUTF2 nuclear transport factor 2 -5.49859
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) -3.6236
TENM2 teneurin transmembrane protein 2 -3.06907
STK4 serine/threonine kinase 4 -2.8274
SEC23A Sec23 homolog A (S. cerevisiae) -2.38805
C5ORF22 chromosome 5 open reading frame 22 -2.37253
PTPRF protein tyrosine phosphatase, receptor type, F -2.37253
MRGBP MRG/MORF4L binding protein -2.07767
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -2.07608
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -1.81867
UBE3C ubiquitin protein ligase E3C -1.6635
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 -1.6635
PTPN11 protein tyrosine phosphatase, non-receptor type 11 -1.61424
SPDL1 spindle apparatus coiled-coil protein 1 -1.61424
AP3M1 adaptor-related protein complex 3, mu 1 subunit -1.61424
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -1.31025