| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting ETV6 in human malignant glioblastoma multiforme tissue (Study accession: SRP273428) (PerturbAtlas) |
| Similar Terms | |
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182 genes differentially expressed following the Perturb_9007_KD_ETV6_SRP273428 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLLP | plasmolipin | 13.0932 |
| HIST1H4I | histone cluster 1, H4i | 8.18485 |
| TRIM14 | tripartite motif containing 14 | 7.41571 |
| KCP | kielin/chordin-like protein | 6.24031 |
| PAX8 | paired box 8 | 5.80216 |
| C11ORF68 | chromosome 11 open reading frame 68 | 5.70334 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 5.69096 |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor | 5.57016 |
| IK | IK cytokine, down-regulator of HLA II | 5.55716 |
| BCAN | brevican | 5.27223 |
| KCNIP1 | Kv channel interacting protein 1 | 5.14926 |
| MARS | methionyl-tRNA synthetase | 4.71015 |
| FAS | Fas cell surface death receptor | 4.67694 |
| GDF9 | growth differentiation factor 9 | 4.50907 |
| SH3D19 | SH3 domain containing 19 | 4.47695 |
| C15ORF40 | chromosome 15 open reading frame 40 | 4.46612 |
| KCTD2 | potassium channel tetramerization domain containing 2 | 4.46612 |
| DLEC1 | deleted in lung and esophageal cancer 1 | 4.43819 |
| ASB6 | ankyrin repeat and SOCS box containing 6 | 3.97838 |
| DDTL | D-dopachrome tautomerase-like | 3.91904 |
| CCDC85B | coiled-coil domain containing 85B | 3.88403 |
| HMGXB3 | HMG box domain containing 3 | 3.43075 |
| ZNF593OS | ZNF593 opposite strand | 3.39859 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 3.39636 |
| GDPGP1 | GDP-D-glucose phosphorylase 1 | 3.37527 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 | 3.22143 |
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 3.18421 |
| TSPAN31 | tetraspanin 31 | 3.07742 |
| DLD | dihydrolipoamide dehydrogenase | 3.03105 |
| PMEL | premelanosome protein | 3.01271 |
| TATDN1 | TatD DNase domain containing 1 | 3.01271 |
| MXD3 | MAX dimerization protein 3 | 2.95275 |
| ZNF232 | zinc finger protein 232 | 2.95275 |
| KLC3 | kinesin light chain 3 | 2.90959 |
| CCDC107 | coiled-coil domain containing 107 | 2.78466 |
| CIRBP | cold inducible RNA binding protein | 2.76749 |
| RPS28 | ribosomal protein S28 | 2.73827 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 2.56894 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 2.51097 |
| ZNF627 | zinc finger protein 627 | 2.47562 |
| RER1 | retention in endoplasmic reticulum sorting receptor 1 | 2.45634 |
| MYL5 | myosin, light chain 5, regulatory | 2.39584 |
| ENOSF1 | enolase superfamily member 1 | 2.37392 |
| MPI | mannose phosphate isomerase | 2.34095 |
| NPRL3 | nitrogen permease regulator-like 3 (S. cerevisiae) | 2.30933 |
| GLMP | glycosylated lysosomal membrane protein | 2.27405 |
| SNX22 | sorting nexin 22 | 2.26492 |
| CCDC159 | coiled-coil domain containing 159 | 2.24656 |
| RSPH9 | radial spoke head 9 homolog (Chlamydomonas) | 2.15319 |
| MTX1 | metaxin 1 | 2.12314 |
| CCDC106 | coiled-coil domain containing 106 | 2.12177 |
| TCHP | trichoplein, keratin filament binding | 2.06588 |
| JSRP1 | junctional sarcoplasmic reticulum protein 1 | 2.06135 |
| PPP2R5D | protein phosphatase 2, regulatory subunit B', delta | 1.97721 |
| C5ORF45 | chromosome 5 open reading frame 45 | 1.88265 |
| WDR55 | WD repeat domain 55 | 1.86827 |
| SERINC4 | serine incorporator 4 | 1.85626 |
| LRTOMT | leucine rich transmembrane and O-methyltransferase domain containing | 1.84457 |
| TMEM79 | transmembrane protein 79 | 1.82923 |
| SPATA1 | spermatogenesis associated 1 | 1.82889 |
| FAM161B | family with sequence similarity 161, member B | 1.82314 |
| PDAP1 | PDGFA associated protein 1 | 1.81383 |
| PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F | 1.79458 |
| MAK | male germ cell-associated kinase | 1.78466 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 1.78197 |
| RHBDL2 | rhomboid, veinlet-like 2 (Drosophila) | 1.76507 |
| NR2C2AP | nuclear receptor 2C2-associated protein | 1.74535 |
| GFAP | glial fibrillary acidic protein | 1.73944 |
| CARM1 | coactivator-associated arginine methyltransferase 1 | 1.7202 |
| TMEM8B | transmembrane protein 8B | 1.7202 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | 1.70059 |
| NUP153 | nucleoporin 153kDa | 1.69105 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | 1.6228 |
| CENPP | centromere protein P | 1.62034 |
| NR1I3 | nuclear receptor subfamily 1, group I, member 3 | 1.61476 |
| GOLGA4 | golgin A4 | 1.58569 |
| FTSJ3 | FtsJ homolog 3 (E. coli) | 1.56177 |
| FAM134C | family with sequence similarity 134, member C | 1.55801 |
| SLC9A3 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 | 1.5198 |
| VPRBP | Vpr (HIV-1) binding protein | 1.51472 |
| PITPNA | phosphatidylinositol transfer protein, alpha | 1.50089 |
| ZFHX3 | zinc finger homeobox 3 | 1.48833 |
| HAS3 | hyaluronan synthase 3 | 1.44422 |
| C9ORF117 | chromosome 9 open reading frame 117 | 1.44152 |
| C12ORF10 | chromosome 12 open reading frame 10 | 1.42695 |
| L3MBTL2 | l(3)mbt-like 2 (Drosophila) | 1.42328 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) | 1.40823 |
| PTCD1 | pentatricopeptide repeat domain 1 | 1.40353 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 | 1.39112 |
| CLK3 | CDC-like kinase 3 | 1.38057 |
| SLC25A35 | solute carrier family 25, member 35 | 1.38057 |
| CCAR2 | cell cycle and apoptosis regulator 2 | 1.3682 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 1.36108 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 | 1.36108 |
| C16ORF70 | chromosome 16 open reading frame 70 | 1.36108 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 1.36108 |
| MSMP | microseminoprotein, prostate associated | 1.35939 |
| UNC45A | unc-45 homolog A (C. elegans) | 1.33793 |
| SMPD3 | sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) | 1.3337 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 | 1.33312 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | -20.0 |
| ORAOV1 | oral cancer overexpressed 1 | -15.3589 |
| C12ORF60 | chromosome 12 open reading frame 60 | -8.56637 |
| FADS1 | fatty acid desaturase 1 | -6.118 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | -5.89467 |
| LCTL | lactase-like | -5.1844 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | -4.82386 |
| TUBA1C | tubulin, alpha 1c | -4.64467 |
| SLC46A1 | solute carrier family 46 (folate transporter), member 1 | -4.50778 |
| MSH6 | mutS homolog 6 | -4.31059 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | -4.10228 |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | -4.08528 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | -3.86833 |
| NUP88 | nucleoporin 88kDa | -3.63459 |
| PCED1B | PC-esterase domain containing 1B | -3.63421 |
| BACE1 | beta-site APP-cleaving enzyme 1 | -3.52153 |
| LOC338667 | V-set and immunoglobulin domain-containing protein 10-like | -3.20937 |
| IAH1 | isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) | -3.15723 |
| SLC5A10 | solute carrier family 5 (sodium/sugar cotransporter), member 10 | -3.1126 |
| UTP23 | UTP23, small subunit (SSU) processome component, homolog (yeast) | -3.03433 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | -2.83446 |
| RBBP4 | retinoblastoma binding protein 4 | -2.80588 |
| SMIM4 | small integral membrane protein 4 | -2.76007 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -2.69914 |
| C9ORF172 | chromosome 9 open reading frame 172 | -2.59119 |
| PLD4 | phospholipase D family, member 4 | -2.45796 |
| RABL6 | RAB, member RAS oncogene family-like 6 | -2.43346 |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) | -2.3974 |
| CDHR5 | cadherin-related family member 5 | -2.36583 |
| ARHGEF39 | Rho guanine nucleotide exchange factor (GEF) 39 | -2.3576 |
| KRT17 | keratin 17, type I | -2.32389 |
| TRIM59 | tripartite motif containing 59 | -2.30195 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 | -2.25621 |
| PSMG4 | proteasome (prosome, macropain) assembly chaperone 4 | -2.24656 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | -2.24656 |
| OTUD4 | OTU deubiquitinase 4 | -2.22285 |
| BEST1 | bestrophin 1 | -2.22285 |
| PGF | placental growth factor | -2.18446 |
| VPS4A | vacuolar protein sorting 4 homolog A (S. cerevisiae) | -2.16963 |
| POLRMT | polymerase (RNA) mitochondrial (DNA directed) | -2.15617 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | -2.15575 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.06003 |
| ANKRD23 | ankyrin repeat domain 23 | -2.03453 |
| COX11 | COX11 cytochrome c oxidase copper chaperone | -1.99826 |
| STK24 | serine/threonine kinase 24 | -1.94898 |
| CCNH | cyclin H | -1.85267 |
| SNRK | SNF related kinase | -1.83657 |
| SLC9A6 | solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 | -1.83584 |
| AIMP1 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 | -1.81383 |
| ASTE1 | asteroid homolog 1 (Drosophila) | -1.81383 |
| CD37 | CD37 molecule | -1.7998 |
| CBR4 | carbonyl reductase 4 | -1.74887 |
| HDLBP | high density lipoprotein binding protein | -1.71545 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -1.71472 |
| UBE2A | ubiquitin-conjugating enzyme E2A | -1.70862 |
| PCDH17 | protocadherin 17 | -1.70146 |
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | -1.68278 |
| LOC122455342 | testis-specific serine/proline-rich protein | -1.67467 |
| SGCE | sarcoglycan, epsilon | -1.67349 |
| PRICKLE3 | prickle homolog 3 (Drosophila) | -1.64674 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -1.63204 |
| DNAH10 | dynein, axonemal, heavy chain 10 | -1.6242 |
| PYROXD1 | pyridine nucleotide-disulphide oxidoreductase domain 1 | -1.58324 |
| APOM | apolipoprotein M | -1.54877 |
| TSPAN4 | tetraspanin 4 | -1.54877 |
| AP4S1 | adaptor-related protein complex 4, sigma 1 subunit | -1.54877 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | -1.5159 |
| DNASE1L2 | deoxyribonuclease I-like 2 | -1.49581 |
| IFT80 | intraflagellar transport 80 | -1.49447 |
| STRADB | STE20-related kinase adaptor beta | -1.49023 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -1.40906 |
| C12ORF73 | chromosome 12 open reading frame 73 | -1.39471 |
| C22ORF23 | chromosome 22 open reading frame 23 | -1.37403 |
| NPC1 | Niemann-Pick disease, type C1 | -1.3682 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 | -1.36108 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -1.35502 |
| GPSM2 | G-protein signaling modulator 2 | -1.35235 |
| MTMR2 | myotubularin related protein 2 | -1.34598 |
| PTRH2 | peptidyl-tRNA hydrolase 2 | -1.33807 |
| LONP2 | lon peptidase 2, peroxisomal | -1.33431 |
| CDAN1 | codanin 1 | -1.31424 |
| SPCS1 | signal peptidase complex subunit 1 homolog (S. cerevisiae) | -1.3106 |
