Perturb_9019_KD_FOXD1_SRP132362 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting FOXD1 in Human mesenchymal stem cells (MSCs) cell line (Study accession: SRP132362) (PerturbAtlas)
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Genes

200 genes differentially expressed following the Perturb_9019_KD_FOXD1_SRP132362 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
PRDX4 peroxiredoxin 4 20.0
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 20.0
CD151 CD151 molecule (Raph blood group) 20.0
SDF4 stromal cell derived factor 4 20.0
BSG basigin (Ok blood group) 20.0
HEXB hexosaminidase B (beta polypeptide) 20.0
TGFBI transforming growth factor, beta-induced, 68kDa 20.0
PGAM1 phosphoglycerate mutase 1 (brain) 20.0
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 20.0
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 20.0
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 20.0
WSB1 WD repeat and SOCS box containing 1 20.0
PLK2 polo-like kinase 2 20.0
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 20.0
NABP1 nucleic acid binding protein 1 20.0
PRSS23 protease, serine, 23 20.0
CCDC80 coiled-coil domain containing 80 20.0
ENC1 ectodermal-neural cortex 1 (with BTB domain) 20.0
VEGFA vascular endothelial growth factor A 20.0
P4HB prolyl 4-hydroxylase, beta polypeptide 20.0
MYL9 myosin, light chain 9, regulatory 20.0
PRPS1 phosphoribosyl pyrophosphate synthetase 1 20.0
GRN granulin 20.0
FN1 fibronectin 1 20.0
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 20.0
LAMC2 laminin, gamma 2 20.0
GAS6 growth arrest-specific 6 20.0
HAPLN1 hyaluronan and proteoglycan link protein 1 20.0
SAT1 spermidine/spermine N1-acetyltransferase 1 20.0
LENG8 leukocyte receptor cluster (LRC) member 8 20.0
GSN gelsolin 20.0
SRPX sushi-repeat containing protein, X-linked 20.0
PGRMC2 progesterone receptor membrane component 2 20.0
THBS1 thrombospondin 1 20.0
NOMO1 NODAL modulator 1 20.0
HTRA1 HtrA serine peptidase 1 20.0
CD46 CD46 molecule, complement regulatory protein 20.0
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 20.0
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 20.0
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 20.0
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 20.0
DCBLD2 discoidin, CUB and LCCL domain containing 2 20.0
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 20.0
PALM2-AKAP2 PALM2-AKAP2 readthrough 20.0
ACTG2 actin, gamma 2, smooth muscle, enteric 20.0
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 20.0
SARAF store-operated calcium entry-associated regulatory factor 20.0
MVP major vault protein 20.0
LDHA lactate dehydrogenase A 20.0
APLP2 amyloid beta (A4) precursor-like protein 2 20.0
TIMP1 TIMP metallopeptidase inhibitor 1 20.0
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 20.0
HM13 histocompatibility (minor) 13 20.0
PGK1 phosphoglycerate kinase 1 20.0
CPA4 carboxypeptidase A4 20.0
SERINC1 serine incorporator 1 20.0
SERINC3 serine incorporator 3 20.0
ITM2B integral membrane protein 2B 20.0
MAMDC2 MAM domain containing 2 20.0
DKK3 dickkopf WNT signaling pathway inhibitor 3 20.0
PLAU plasminogen activator, urokinase 20.0
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 20.0
PVR poliovirus receptor 20.0
COL1A2 collagen, type I, alpha 2 20.0
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 20.0
GLIPR1 GLI pathogenesis-related 1 20.0
GPC1 glypican 1 20.0
CHPF chondroitin polymerizing factor 20.0
PAM peptidylglycine alpha-amidating monooxygenase 20.0
RGS5 regulator of G-protein signaling 5 20.0
CTSB cathepsin B 20.0
PLD3 phospholipase D family, member 3 20.0
ITGB5 integrin, beta 5 20.0
LRP1 low density lipoprotein receptor-related protein 1 20.0
PLAT plasminogen activator, tissue 20.0
PSAP prosaposin 20.0
LAMP1 lysosomal-associated membrane protein 1 20.0
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 20.0
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 20.0
DLG1 discs, large homolog 1 (Drosophila) 20.0
TMEM158 transmembrane protein 158 (gene/pseudogene) 20.0
TGM2 transglutaminase 2 20.0
CAST calpastatin 20.0
BCAP31 B-cell receptor-associated protein 31 20.0
ANGPTL4 angiopoietin-like 4 20.0
ANPEP alanyl (membrane) aminopeptidase 20.0
JUN jun proto-oncogene 20.0
CERCAM cerebral endothelial cell adhesion molecule 20.0
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 20.0
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 20.0
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 20.0
IGFBP3 insulin-like growth factor binding protein 3 20.0
IGFBP7 insulin-like growth factor binding protein 7 20.0
IGFBP5 insulin-like growth factor binding protein 5 20.0
MFGE8 milk fat globule-EGF factor 8 protein 20.0
KRT18 keratin 18, type I 20.0
TMEM59 transmembrane protein 59 20.0
QSOX1 quiescin Q6 sulfhydryl oxidase 1 20.0
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 20.0
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 20.0

decreased expression

Symbol Name Standardized Value
KIF22 kinesin family member 22 -20.0
CDC45 cell division cycle 45 -20.0
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 -20.0
CCNB2 cyclin B2 -20.0
H1F0 H1 histone family, member 0 -20.0
ASF1B anti-silencing function 1B histone chaperone -20.0
FAM83D family with sequence similarity 83, member D -20.0
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) -20.0
FAM167A family with sequence similarity 167, member A -20.0
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -20.0
MCM10 minichromosome maintenance complex component 10 -20.0
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) -20.0
TIMELESS timeless circadian clock -20.0
FBXO5 F-box protein 5 -20.0
PLK4 polo-like kinase 4 -20.0
DBF4 DBF4 zinc finger -20.0
SGOL2 shugoshin-like 2 (S. pombe) -20.0
SHCBP1 SHC SH2-domain binding protein 1 -20.0
KIF20B kinesin family member 20B -20.0
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -20.0
EPS8 epidermal growth factor receptor pathway substrate 8 -20.0
CXCL8 chemokine (C-X-C motif) ligand 8 -20.0
UBE2T ubiquitin-conjugating enzyme E2T -20.0
VRK1 vaccinia related kinase 1 -20.0
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -20.0
SCARA3 scavenger receptor class A, member 3 -20.0
SPC25 SPC25, NDC80 kinetochore complex component -20.0
SPC24 SPC24, NDC80 kinetochore complex component -20.0
MDK midkine (neurite growth-promoting factor 2) -20.0
HJURP Holliday junction recognition protein -20.0
TTK TTK protein kinase -20.0
NDC80 NDC80 kinetochore complex component -20.0
WDR62 WD repeat domain 62 -20.0
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 -20.0
PHF19 PHD finger protein 19 -20.0
FKBP5 FK506 binding protein 5 -20.0
IQGAP3 IQ motif containing GTPase activating protein 3 -20.0
TRIP13 thyroid hormone receptor interactor 13 -20.0
SOCS2 suppressor of cytokine signaling 2 -20.0
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) -20.0
CDC6 cell division cycle 6 -20.0
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b -20.0
DEPDC1 DEP domain containing 1 -20.0
CDK2 cyclin-dependent kinase 2 -20.0
MIS18BP1 MIS18 binding protein 1 -20.0
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -20.0
ORC6 origin recognition complex, subunit 6 -20.0
MRPL36 mitochondrial ribosomal protein L36 -20.0
GINS2 GINS complex subunit 2 (Psf2 homolog) -20.0
PDE4B phosphodiesterase 4B, cAMP-specific -20.0
KIAA1524 KIAA1524 -20.0
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -20.0
CEMIP cell migration inducing protein, hyaluronan binding -20.0
ADARB1 adenosine deaminase, RNA-specific, B1 -20.0
KISS1 KiSS-1 metastasis-suppressor -20.0
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -20.0
RFC4 replication factor C (activator 1) 4, 37kDa -20.0
TROAP trophinin associated protein -20.0
CASC5 cancer susceptibility candidate 5 -20.0
SYNE2 spectrin repeat containing, nuclear envelope 2 -20.0
RAD51AP1 RAD51 associated protein 1 -20.0
RELN reelin -20.0
CDCA8 cell division cycle associated 8 -20.0
CDCA5 cell division cycle associated 5 -20.0
FAM64A family with sequence similarity 64, member A -20.0
SKA1 spindle and kinetochore associated complex subunit 1 -20.0
SKA3 spindle and kinetochore associated complex subunit 3 -20.0
BTG3 BTG family, member 3 -20.0
FANCG Fanconi anemia, complementation group G -20.0
FANCI Fanconi anemia, complementation group I -20.0
CPXM1 carboxypeptidase X (M14 family), member 1 -20.0
KNTC1 kinetochore associated 1 -20.0
CDCA2 cell division cycle associated 2 -20.0
CDCA3 cell division cycle associated 3 -20.0
GTSE1 G-2 and S-phase expressed 1 -20.0
SULF1 sulfatase 1 -20.0
CENPK centromere protein K -20.0
CENPU centromere protein U -20.0
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -20.0
MDFI MyoD family inhibitor -20.0
SPAG5 sperm associated antigen 5 -20.0
HIC1 hypermethylated in cancer 1 -20.0
NPTX1 neuronal pentraxin I -20.0
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -20.0
GMNN geminin, DNA replication inhibitor -20.0
KIF2C kinesin family member 2C -20.0
PSRC1 proline/serine-rich coiled-coil 1 -20.0
KIF15 kinesin family member 15 -20.0
KIF14 kinesin family member 14 -20.0
GULP1 GULP, engulfment adaptor PTB domain containing 1 -20.0
AURKB aurora kinase B -20.0
KIF4A kinesin family member 4A -20.0
NCAPH non-SMC condensin I complex, subunit H -20.0
PDGFA platelet-derived growth factor alpha polypeptide -20.0
KIF18A kinesin family member 18A -20.0
KIF18B kinesin family member 18B -20.0
CKAP2L cytoskeleton associated protein 2-like -20.0
TCF19 transcription factor 19 -20.0
HMMR hyaluronan-mediated motility receptor (RHAMM) -20.0
BRCA1 breast cancer 1, early onset -20.0