| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting KDM2B in human umbilical vein endothelial cells cell line (Study accession: SRP359233) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_9128_KD_KDM2B_SRP359233 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 20.0 |
| FBLN5 | fibulin 5 | 20.0 |
| MYLIP | myosin regulatory light chain interacting protein | 20.0 |
| PDZD2 | PDZ domain containing 2 | 20.0 |
| PRNP | prion protein | 20.0 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | 20.0 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 20.0 |
| KRT7 | keratin 7, type II | 20.0 |
| SULF2 | sulfatase 2 | 20.0 |
| MMP2 | matrix metallopeptidase 2 | 20.0 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 20.0 |
| STAG1 | stromal antigen 1 | 20.0 |
| SDC2 | syndecan 2 | 20.0 |
| MYL9 | myosin, light chain 9, regulatory | 20.0 |
| THSD4 | thrombospondin, type I, domain containing 4 | 20.0 |
| FN1 | fibronectin 1 | 20.0 |
| COL5A1 | collagen, type V, alpha 1 | 20.0 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 20.0 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 20.0 |
| TRIQK | triple QxxK/R motif containing | 20.0 |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs | 20.0 |
| CXADR | coxsackie virus and adenovirus receptor | 20.0 |
| COL4A1 | collagen, type IV, alpha 1 | 20.0 |
| LOX | lysyl oxidase | 20.0 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 20.0 |
| GAS6 | growth arrest-specific 6 | 20.0 |
| SPATA18 | spermatogenesis associated 18 | 20.0 |
| BGN | biglycan | 20.0 |
| TAGLN | transgelin | 20.0 |
| COL1A2 | collagen, type I, alpha 2 | 20.0 |
| COL4A2 | collagen, type IV, alpha 2 | 20.0 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 20.0 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | 20.0 |
| MAMDC2 | MAM domain containing 2 | 20.0 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 20.0 |
| ADAM9 | ADAM metallopeptidase domain 9 | 20.0 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 19.699 |
| TPM1 | tropomyosin 1 (alpha) | 19.699 |
| SGPL1 | sphingosine-1-phosphate lyase 1 | 19.5229 |
| MYL12B | myosin, light chain 12B, regulatory | 19.3979 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 18.6021 |
| SNCAIP | synuclein, alpha interacting protein | 18.5686 |
| CDH13 | cadherin 13 | 18.3565 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 18.1079 |
| PCDHGA4 | protocadherin gamma subfamily A, 4 | 17.9586 |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) | 17.752 |
| SEPT4 | septin 4 | 17.2291 |
| CXORF36 | chromosome X open reading frame 36 | 17.1851 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 17.1141 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 17.1141 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 16.87 |
| FAM107A | family with sequence similarity 107, member A | 16.7929 |
| SGCE | sarcoglycan, epsilon | 16.679 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 16.6284 |
| ATP13A2 | ATPase type 13A2 | 16.4508 |
| FADS3 | fatty acid desaturase 3 | 16.4432 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 16.4229 |
| ANGPTL4 | angiopoietin-like 4 | 16.2297 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 | 16.0408 |
| TMEM30A | transmembrane protein 30A | 15.7938 |
| VWCE | von Willebrand factor C and EGF domains | 15.7804 |
| GPC5 | glypican 5 | 15.6015 |
| ADAM23 | ADAM metallopeptidase domain 23 | 15.5579 |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) | 15.5566 |
| NPTN | neuroplastin | 15.3095 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 15.2566 |
| NOTCH4 | notch 4 | 15.1182 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 15.1107 |
| ZMAT3 | zinc finger, matrin-type 3 | 15.1089 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 | 14.5898 |
| LAMC2 | laminin, gamma 2 | 14.3282 |
| FSTL1 | follistatin-like 1 | 14.3031 |
| OLFML3 | olfactomedin-like 3 | 14.2033 |
| DPY19L3 | dpy-19-like 3 (C. elegans) | 14.1174 |
| OSBPL10 | oxysterol binding protein-like 10 | 13.9443 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | 13.8753 |
| CYBRD1 | cytochrome b reductase 1 | 13.8745 |
| PLSCR4 | phospholipid scramblase 4 | 13.8376 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 13.8342 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 13.7192 |
| TSPAN2 | tetraspanin 2 | 13.6501 |
| CSMD1 | CUB and Sushi multiple domains 1 | 13.6004 |
| ZC3H7B | zinc finger CCCH-type containing 7B | 13.5002 |
| RELN | reelin | 13.3828 |
| CELF2 | CUGBP, Elav-like family member 2 | 13.3399 |
| ITGA11 | integrin, alpha 11 | 13.3271 |
| MAGED1 | melanoma antigen family D1 | 13.1745 |
| EFHD2 | EF-hand domain family, member D2 | 13.0825 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 13.0586 |
| FAM73A | family with sequence similarity 73, member A | 13.0548 |
| SESN2 | sestrin 2 | 13.0484 |
| LPIN2 | lipin 2 | 13.0484 |
| CALD1 | caldesmon 1 | 12.8964 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 12.8852 |
| TXNRD2 | thioredoxin reductase 2 | 12.8662 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 12.7735 |
| THSD7A | thrombospondin, type I, domain containing 7A | 12.7668 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | 12.5508 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 12.4693 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 12.3601 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CEP55 | centrosomal protein 55kDa | -20.0 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | -20.0 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -20.0 |
| UBE2T | ubiquitin-conjugating enzyme E2T | -20.0 |
| ARHGAP11A | Rho GTPase activating protein 11A | -20.0 |
| FANCD2 | Fanconi anemia, complementation group D2 | -20.0 |
| CHTF18 | CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) | -20.0 |
| CDC45 | cell division cycle 45 | -20.0 |
| CCNB2 | cyclin B2 | -20.0 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -20.0 |
| EXO1 | exonuclease 1 | -20.0 |
| KIF20A | kinesin family member 20A | -20.0 |
| KIF20B | kinesin family member 20B | -20.0 |
| CIT | citron rho-interacting serine/threonine kinase | -20.0 |
| KIF2C | kinesin family member 2C | -20.0 |
| BRCA1 | breast cancer 1, early onset | -20.0 |
| KIF23 | kinesin family member 23 | -20.0 |
| KIF22 | kinesin family member 22 | -20.0 |
| CCDC34 | coiled-coil domain containing 34 | -20.0 |
| PLK4 | polo-like kinase 4 | -20.0 |
| DBF4 | DBF4 zinc finger | -20.0 |
| SGOL2 | shugoshin-like 2 (S. pombe) | -20.0 |
| SHCBP1 | SHC SH2-domain binding protein 1 | -20.0 |
| OXCT1 | 3-oxoacid CoA transferase 1 | -20.0 |
| ASF1B | anti-silencing function 1B histone chaperone | -20.0 |
| DEPDC1B | DEP domain containing 1B | -20.0 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | -20.0 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | -20.0 |
| TRIP13 | thyroid hormone receptor interactor 13 | -20.0 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | -20.0 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -20.0 |
| SPC24 | SPC24, NDC80 kinetochore complex component | -20.0 |
| HJURP | Holliday junction recognition protein | -20.0 |
| TTK | TTK protein kinase | -20.0 |
| NDC80 | NDC80 kinetochore complex component | -20.0 |
| DHFR | dihydrofolate reductase | -20.0 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -20.0 |
| CENPA | centromere protein A | -20.0 |
| DEPDC1 | DEP domain containing 1 | -20.0 |
| RACGAP1 | Rac GTPase activating protein 1 | -20.0 |
| MCM10 | minichromosome maintenance complex component 10 | -20.0 |
| CETN2 | centrin, EF-hand protein, 2 | -20.0 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -20.0 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | -20.0 |
| PTTG1 | pituitary tumor-transforming 1 | -20.0 |
| E2F1 | E2F transcription factor 1 | -20.0 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | -20.0 |
| TMEM97 | transmembrane protein 97 | -20.0 |
| ACP5 | acid phosphatase 5, tartrate resistant | -20.0 |
| SAPCD2 | suppressor APC domain containing 2 | -20.0 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -20.0 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -20.0 |
| CCDC25 | coiled-coil domain containing 25 | -20.0 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | -20.0 |
| ATAD2 | ATPase family, AAA domain containing 2 | -20.0 |
| TROAP | trophinin associated protein | -20.0 |
| PBK | PDZ binding kinase | -20.0 |
| UHRF1 | ubiquitin-like with PHD and ring finger domains 1 | -20.0 |
| CASC5 | cancer susceptibility candidate 5 | -20.0 |
| GTSE1 | G-2 and S-phase expressed 1 | -20.0 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | -20.0 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -20.0 |
| CDCA8 | cell division cycle associated 8 | -20.0 |
| CDCA5 | cell division cycle associated 5 | -20.0 |
| KIAA1524 | KIAA1524 | -20.0 |
| FAM64A | family with sequence similarity 64, member A | -20.0 |
| SKA1 | spindle and kinetochore associated complex subunit 1 | -20.0 |
| SKA3 | spindle and kinetochore associated complex subunit 3 | -20.0 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -20.0 |
| RYK | receptor-like tyrosine kinase | -20.0 |
| KIFC1 | kinesin family member C1 | -20.0 |
| FAM111B | family with sequence similarity 111, member B | -20.0 |
| CDCA2 | cell division cycle associated 2 | -20.0 |
| CDCA3 | cell division cycle associated 3 | -20.0 |
| NEK2 | NIMA-related kinase 2 | -20.0 |
| AURKA | aurora kinase A | -20.0 |
| CKAP2L | cytoskeleton associated protein 2-like | -20.0 |
| TCF19 | transcription factor 19 | -20.0 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -20.0 |
| KIF15 | kinesin family member 15 | -20.0 |
| KIF11 | kinesin family member 11 | -20.0 |
| CENPM | centromere protein M | -20.0 |
| CENPI | centromere protein I | -20.0 |
| CENPE | centromere protein E, 312kDa | -20.0 |
| CENPU | centromere protein U | -20.0 |
| MELK | maternal embryonic leucine zipper kinase | -20.0 |
| KIF18B | kinesin family member 18B | -20.0 |
| KIF18A | kinesin family member 18A | -20.0 |
| CDC25C | cell division cycle 25C | -20.0 |
| AURKB | aurora kinase B | -20.0 |
| KRT17 | keratin 17, type I | -20.0 |
| KIF4A | kinesin family member 4A | -20.0 |
| ZWINT | ZW10 interacting kinetochore protein | -20.0 |
| INCENP | inner centromere protein antigens 135/155kDa | -20.0 |
| NUF2 | NUF2, NDC80 kinetochore complex component | -20.0 |
| NCAPH | non-SMC condensin I complex, subunit H | -20.0 |
| NCAPG | non-SMC condensin I complex, subunit G | -20.0 |
| TK1 | thymidine kinase 1, soluble | -20.0 |
| CCNF | cyclin F | -20.0 |
| SPAG5 | sperm associated antigen 5 | -20.0 |
