| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting ENL in iCas9-MOLM-13 cell line (Study accession: SRP074134) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_9238_KD_ENL_SRP074134 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 20.0 |
| EPAS1 | endothelial PAS domain protein 1 | 16.7118 |
| NANOS1 | nanos homolog 1 (Drosophila) | 16.605 |
| SOCS3 | suppressor of cytokine signaling 3 | 13.5909 |
| TP53INP2 | tumor protein p53 inducible nuclear protein 2 | 12.9778 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 11.6551 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 10.7697 |
| SMIM3 | small integral membrane protein 3 | 10.6908 |
| ITGA6 | integrin, alpha 6 | 10.2951 |
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | 9.56227 |
| SCUBE1 | signal peptide, CUB domain, EGF-like 1 | 9.56227 |
| RGS1 | regulator of G-protein signaling 1 | 9.49313 |
| CD38 | CD38 molecule | 9.36502 |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 | 8.94097 |
| RAB37 | RAB37, member RAS oncogene family | 8.93076 |
| FURIN | furin (paired basic amino acid cleaving enzyme) | 8.45086 |
| BEX1 | brain expressed, X-linked 1 | 8.2664 |
| TMEM116 | transmembrane protein 116 | 8.22497 |
| IDUA | iduronidase, alpha-L- | 8.1679 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | 8.03325 |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 | 7.79812 |
| FAM20C | family with sequence similarity 20, member C | 7.68243 |
| GRN | granulin | 7.56009 |
| SLC37A2 | solute carrier family 37 (glucose-6-phosphate transporter), member 2 | 7.35399 |
| FOXO1 | forkhead box O1 | 6.98354 |
| SERINC2 | serine incorporator 2 | 6.73552 |
| OLIG1 | oligodendrocyte transcription factor 1 | 6.72376 |
| NCF1 | neutrophil cytosolic factor 1 | 6.55464 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 6.47447 |
| COL9A2 | collagen, type IX, alpha 2 | 6.40563 |
| PSAP | prosaposin | 6.29815 |
| C19ORF35 | chromosome 19 open reading frame 35 | 6.17213 |
| KSR1 | kinase suppressor of ras 1 | 5.81447 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 5.77706 |
| MYOF | myoferlin | 5.67047 |
| TGM5 | transglutaminase 5 | 5.6525 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 5.33144 |
| CD209 | CD209 molecule | 5.33144 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 5.20681 |
| RBM47 | RNA binding motif protein 47 | 5.10753 |
| SLC43A2 | solute carrier family 43 (amino acid system L transporter), member 2 | 5.06645 |
| S1PR3 | sphingosine-1-phosphate receptor 3 | 4.94815 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) | 4.91431 |
| VENTX | VENT homeobox | 4.88824 |
| MSC | musculin | 4.88824 |
| NHSL2 | NHS-like 2 | 4.88824 |
| SRGN | serglycin | 4.83539 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 4.83539 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B | 4.83539 |
| KLF4 | Kruppel-like factor 4 (gut) | 4.81115 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 | 4.73857 |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 | 4.67916 |
| BMP2 | bone morphogenetic protein 2 | 4.66314 |
| JUN | jun proto-oncogene | 4.66314 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 4.6048 |
| NXF3 | nuclear RNA export factor 3 | 4.59065 |
| TYMP | thymidine phosphorylase | 4.53568 |
| REEP6 | receptor accessory protein 6 | 4.47831 |
| CFD | complement factor D (adipsin) | 4.41284 |
| C3ORF80 | chromosome 3 open reading frame 80 | 4.37586 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 4.30761 |
| CCDC159 | coiled-coil domain containing 159 | 4.29493 |
| TAOK3 | TAO kinase 3 | 4.24539 |
| MARCH2 | membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase | 4.24539 |
| CD82 | CD82 molecule | 4.21504 |
| HMOX1 | heme oxygenase 1 | 4.18822 |
| BIN2 | bridging integrator 2 | 4.17479 |
| CD1D | CD1d molecule | 4.12256 |
| CSF1R | colony stimulating factor 1 receptor | 4.08005 |
| NFAM1 | NFAT activating protein with ITAM motif 1 | 4.0095 |
| CCNA1 | cyclin A1 | 3.98178 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 3.95384 |
| ATXN1 | ataxin 1 | 3.93519 |
| NFE2 | nuclear factor, erythroid 2 | 3.88596 |
| MMP2 | matrix metallopeptidase 2 | 3.81098 |
| SDSL | serine dehydratase-like | 3.80476 |
| NPTXR | neuronal pentraxin receptor | 3.77872 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 3.76742 |
| FTH1 | ferritin, heavy polypeptide 1 | 3.76354 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 3.72792 |
| COL6A3 | collagen, type VI, alpha 3 | 3.71348 |
| SMOX | spermine oxidase | 3.68282 |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 | 3.67543 |
| EGR1 | early growth response 1 | 3.67499 |
| IQSEC2 | IQ motif and Sec7 domain 2 | 3.66242 |
| PLXDC2 | plexin domain containing 2 | 3.63355 |
| ELANE | elastase, neutrophil expressed | 3.51618 |
| PIWIL4 | piwi-like RNA-mediated gene silencing 4 | 3.51238 |
| FGFR3 | fibroblast growth factor receptor 3 | 3.4973 |
| ARSA | arylsulfatase A | 3.47217 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 3.4113 |
| ADCY9 | adenylate cyclase 9 | 3.41014 |
| NRBP2 | nuclear receptor binding protein 2 | 3.33514 |
| VPS9D1 | VPS9 domain containing 1 | 3.2316 |
| DLX2 | distal-less homeobox 2 | 3.22747 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | 3.21211 |
| CA8 | carbonic anhydrase VIII | 3.19542 |
| EVI5L | ecotropic viral integration site 5-like | 3.18033 |
| DUSP6 | dual specificity phosphatase 6 | 3.15371 |
| FES | FES proto-oncogene, tyrosine kinase | 3.15133 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RAPSN | receptor-associated protein of the synapse | -20.0 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -18.4202 |
| CCR2 | chemokine (C-C motif) receptor 2 | -16.7844 |
| FAM129C | family with sequence similarity 129, member C | -16.605 |
| DDN | dendrin | -12.7096 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -12.2667 |
| ZNF395 | zinc finger protein 395 | -11.6551 |
| MPO | myeloperoxidase | -11.3784 |
| INSIG1 | insulin induced gene 1 | -10.6557 |
| ACPP | acid phosphatase, prostate | -10.6487 |
| KIAA0226L | KIAA0226-like | -9.94374 |
| DTX4 | deltex 4, E3 ubiquitin ligase | -9.43967 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 | -9.0071 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -8.84218 |
| TBC1D30 | TBC1 domain family, member 30 | -7.56009 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -6.97578 |
| TMEM45A | transmembrane protein 45A | -6.87969 |
| CTSG | cathepsin G | -6.73736 |
| KLHL13 | kelch-like family member 13 | -6.68196 |
| ARL4C | ADP-ribosylation factor-like 4C | -6.55464 |
| IL7R | interleukin 7 receptor | -6.02999 |
| MPEG1 | macrophage expressed 1 | -5.61082 |
| SLC38A5 | solute carrier family 38, member 5 | -5.48299 |
| AFF3 | AF4/FMR2 family, member 3 | -5.4687 |
| ALDOC | aldolase C, fructose-bisphosphate | -5.29611 |
| HEG1 | heart development protein with EGF-like domains 1 | -5.27047 |
| C12ORF75 | chromosome 12 open reading frame 75 | -4.88824 |
| MFAP4 | microfibrillar-associated protein 4 | -4.85069 |
| MLLT1 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 | -4.70628 |
| PM20D2 | peptidase M20 domain containing 2 | -4.66314 |
| NXT2 | nuclear transport factor 2-like export factor 2 | -4.66314 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -4.66314 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -4.43602 |
| CCNG2 | cyclin G2 | -4.40834 |
| BLNK | B-cell linker | -4.30761 |
| DZIP1 | DAZ interacting zinc finger protein 1 | -4.30418 |
| FADS1 | fatty acid desaturase 1 | -4.24539 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -4.24539 |
| CSRP2 | cysteine and glycine-rich protein 2 | -4.11508 |
| DDIT4 | DNA-damage-inducible transcript 4 | -4.09126 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | -4.07112 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | -4.01139 |
| SLC38A1 | solute carrier family 38, member 1 | -3.85233 |
| STC2 | stanniocalcin 2 | -3.83673 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -3.76678 |
| MT1X | metallothionein 1X | -3.67499 |
| CA2 | carbonic anhydrase II | -3.58587 |
| SHISA2 | shisa family member 2 | -3.54115 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | -3.50323 |
| GPT2 | glutamic pyruvate transaminase (alanine aminotransferase) 2 | -3.47217 |
| PHGDH | phosphoglycerate dehydrogenase | -3.29041 |
| TXNIP | thioredoxin interacting protein | -3.27609 |
| ABCD2 | ATP-binding cassette, sub-family D (ALD), member 2 | -3.27609 |
| TEX15 | testis expressed 15 | -3.21515 |
| DHCR7 | 7-dehydrocholesterol reductase | -3.21212 |
| SIDT1 | SID1 transmembrane family, member 1 | -3.18183 |
| ZBED3 | zinc finger, BED-type containing 3 | -3.11124 |
| TMEM135 | transmembrane protein 135 | -3.06936 |
| PDE4A | phosphodiesterase 4A, cAMP-specific | -3.04895 |
| ETV1 | ets variant 1 | -3.00116 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -2.98475 |
| TERT | telomerase reverse transcriptase | -2.98294 |
| RRM2 | ribonucleotide reductase M2 | -2.92358 |
| C10ORF10 | chromosome 10 open reading frame 10 | -2.92153 |
| AJUBA | ajuba LIM protein | -2.91949 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -2.91949 |
| CCR1 | chemokine (C-C motif) receptor 1 | -2.87195 |
| PSAT1 | phosphoserine aminotransferase 1 | -2.83527 |
| SQLE | squalene epoxidase | -2.83527 |
| KIF15 | kinesin family member 15 | -2.8291 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -2.8291 |
| GUCY2C | guanylate cyclase 2C | -2.79507 |
| ALDH1L2 | aldehyde dehydrogenase 1 family, member L2 | -2.76033 |
| TMEM255A | transmembrane protein 255A | -2.76033 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) | -2.74806 |
| TTK | TTK protein kinase | -2.64888 |
| ELAVL4 | ELAV like neuron-specific RNA binding protein 4 | -2.58138 |
| UNG | uracil-DNA glycosylase | -2.57958 |
| MCM10 | minichromosome maintenance complex component 10 | -2.5724 |
| DEPDC1B | DEP domain containing 1B | -2.5724 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -2.55122 |
| FERMT1 | fermitin family member 1 | -2.49039 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | -2.48222 |
| NCAPG | non-SMC condensin I complex, subunit G | -2.46262 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 | -2.45788 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -2.45497 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | -2.45497 |
| SLITRK5 | SLIT and NTRK-like family, member 5 | -2.43935 |
| ULBP1 | UL16 binding protein 1 | -2.43383 |
| UHRF1 | ubiquitin-like with PHD and ring finger domains 1 | -2.41012 |
| CAMKV | CaM kinase-like vesicle-associated | -2.34838 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -2.27961 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -2.25358 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) | -2.25358 |
| KIAA1147 | KIAA1147 | -2.23861 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -2.23669 |
| MCM6 | minichromosome maintenance complex component 6 | -2.22675 |
| MSH2 | mutS homolog 2 | -2.21575 |
| SLC16A9 | solute carrier family 16, member 9 | -2.21575 |
| HMGN5 | high mobility group nucleosome binding domain 5 | -2.20946 |
