| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KO perturbation targeting RNASEH2B in iPSC-derived neurons cell line (Study accession: SRP355094) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_9699_KO_RNASEH2B_SRP355094 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 20.0 |
| OLFM1 | olfactomedin 1 | 20.0 |
| CHGA | chromogranin A | 20.0 |
| CHGB | chromogranin B | 20.0 |
| TUBB4A | tubulin, beta 4A class IVa | 20.0 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 | 20.0 |
| HES6 | hes family bHLH transcription factor 6 | 20.0 |
| PDIA2 | protein disulfide isomerase family A, member 2 | 20.0 |
| CELF4 | CUGBP, Elav-like family member 4 | 20.0 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 20.0 |
| SEPT3 | septin 3 | 20.0 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 20.0 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) | 20.0 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 20.0 |
| KIF1A | kinesin family member 1A | 20.0 |
| PGM2L1 | phosphoglucomutase 2-like 1 | 20.0 |
| IRX2 | iroquois homeobox 2 | 20.0 |
| CNTN2 | contactin 2 (axonal) | 20.0 |
| EPHB1 | EPH receptor B1 | 20.0 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 20.0 |
| GRIN2D | glutamate receptor, ionotropic, N-methyl D-aspartate 2D | 20.0 |
| NOVA1 | neuro-oncological ventral antigen 1 | 20.0 |
| FST | follistatin | 20.0 |
| PHYHIPL | phytanoyl-CoA 2-hydroxylase interacting protein-like | 20.0 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | 20.0 |
| SOX2 | SRY (sex determining region Y)-box 2 | 20.0 |
| FGFBP3 | fibroblast growth factor binding protein 3 | 20.0 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 20.0 |
| DLK1 | delta-like 1 homolog (Drosophila) | 20.0 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 20.0 |
| SYT13 | synaptotagmin XIII | 20.0 |
| SYT11 | synaptotagmin XI | 20.0 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | 20.0 |
| NAT8L | N-acetyltransferase 8-like (GCN5-related, putative) | 20.0 |
| STMN2 | stathmin 2 | 20.0 |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 | 20.0 |
| CNTFR | ciliary neurotrophic factor receptor | 20.0 |
| TUBB2B | tubulin, beta 2B class IIb | 20.0 |
| ADGRB1 | adhesion G protein-coupled receptor B1 | 20.0 |
| ADCYAP1R1 | adenylate cyclase activating polypeptide 1 (pituitary) receptor type I | 20.0 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 20.0 |
| TMEM59L | transmembrane protein 59-like | 20.0 |
| ELAVL4 | ELAV like neuron-specific RNA binding protein 4 | 20.0 |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 | 20.0 |
| PTPRN | protein tyrosine phosphatase, receptor type, N | 20.0 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 | 20.0 |
| CBLN1 | cerebellin 1 precursor | 20.0 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 20.0 |
| C1QL4 | complement component 1, q subcomponent-like 4 | 20.0 |
| LINGO1 | leucine rich repeat and Ig domain containing 1 | 20.0 |
| SLC17A6 | solute carrier family 17 (vesicular glutamate transporter), member 6 | 20.0 |
| NRCAM | neuronal cell adhesion molecule | 20.0 |
| TMEM178B | transmembrane protein 178B | 20.0 |
| MAP2 | microtubule-associated protein 2 | 20.0 |
| MAPT | microtubule-associated protein tau | 20.0 |
| RELN | reelin | 20.0 |
| ENO2 | enolase 2 (gamma, neuronal) | 20.0 |
| FBXO41 | F-box protein 41 | 20.0 |
| PCDH17 | protocadherin 17 | 20.0 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 20.0 |
| CCDC184 | coiled-coil domain containing 184 | 20.0 |
| CD24 | CD24 molecule | 20.0 |
| DCC | DCC netrin 1 receptor | 20.0 |
| TRIM9 | tripartite motif containing 9 | 20.0 |
| SYT5 | synaptotagmin V | 20.0 |
| SYP | synaptophysin | 20.0 |
| VGF | VGF nerve growth factor inducible | 20.0 |
| LMX1B | LIM homeobox transcription factor 1, beta | 20.0 |
| MEIS2 | Meis homeobox 2 | 20.0 |
| MEIS1 | Meis homeobox 1 | 20.0 |
| FAIM2 | Fas apoptotic inhibitory molecule 2 | 20.0 |
| RTN1 | reticulon 1 | 20.0 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 20.0 |
| CALY | calcyon neuron-specific vesicular protein | 20.0 |
| C1ORF95 | chromosome 1 open reading frame 95 | 20.0 |
| MAB21L1 | mab-21-like 1 (C. elegans) | 20.0 |
| CDH8 | cadherin 8, type 2 | 20.0 |
| FBLL1 | fibrillarin-like 1 | 20.0 |
| SCN3B | sodium channel, voltage gated, type III beta subunit | 20.0 |
| STOX2 | storkhead box 2 | 20.0 |
| KIF26B | kinesin family member 26B | 20.0 |
| NPAS3 | neuronal PAS domain protein 3 | 20.0 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | 20.0 |
| FGF13 | fibroblast growth factor 13 | 20.0 |
| REEP1 | receptor accessory protein 1 | 20.0 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 | 20.0 |
| HMP19 | HMP19 protein | 20.0 |
| CSPG5 | chondroitin sulfate proteoglycan 5 (neuroglycan C) | 20.0 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | 20.0 |
| NEGR1 | neuronal growth regulator 1 | 20.0 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta | 20.0 |
| KIF21A | kinesin family member 21A | 20.0 |
| RIMS3 | regulating synaptic membrane exocytosis 3 | 20.0 |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 | 20.0 |
| PSD | pleckstrin and Sec7 domain containing | 20.0 |
| PEG10 | paternally expressed 10 | 20.0 |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) | 20.0 |
| BAIAP3 | BAI1-associated protein 3 | 20.0 |
| EDNRB | endothelin receptor type B | 20.0 |
| PTPN5 | protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | -20.0 |
| SKOR2 | SKI family transcriptional corepressor 2 | -20.0 |
| PDZD2 | PDZ domain containing 2 | -20.0 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -20.0 |
| PPP1R1B | protein phosphatase 1, regulatory (inhibitor) subunit 1B | -20.0 |
| TBX15 | T-box 15 | -20.0 |
| PDLIM1 | PDZ and LIM domain 1 | -20.0 |
| EPAS1 | endothelial PAS domain protein 1 | -20.0 |
| TMEM173 | transmembrane protein 173 | -20.0 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -20.0 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -20.0 |
| PAX8 | paired box 8 | -20.0 |
| COL8A2 | collagen, type VIII, alpha 2 | -20.0 |
| LDLRAP1 | low density lipoprotein receptor adaptor protein 1 | -20.0 |
| TMC6 | transmembrane channel-like 6 | -20.0 |
| BMP4 | bone morphogenetic protein 4 | -20.0 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -20.0 |
| LATS2 | large tumor suppressor kinase 2 | -20.0 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -20.0 |
| PERP | PERP, TP53 apoptosis effector | -20.0 |
| ARSI | arylsulfatase family, member I | -20.0 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -20.0 |
| CA8 | carbonic anhydrase VIII | -20.0 |
| MFAP5 | microfibrillar associated protein 5 | -20.0 |
| ZNF503 | zinc finger protein 503 | -20.0 |
| CARD10 | caspase recruitment domain family, member 10 | -20.0 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 | -20.0 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -20.0 |
| KDR | kinase insert domain receptor | -20.0 |
| EMILIN2 | elastin microfibril interfacer 2 | -20.0 |
| FOXC2 | forkhead box C2 | -20.0 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -20.0 |
| ALX4 | ALX homeobox 4 | -20.0 |
| COL24A1 | collagen, type XXIV, alpha 1 | -20.0 |
| GRAMD3 | GRAM domain containing 3 | -20.0 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | -20.0 |
| HAPLN3 | hyaluronan and proteoglycan link protein 3 | -20.0 |
| ZIC3 | Zic family member 3 | -20.0 |
| MEOX2 | mesenchyme homeobox 2 | -20.0 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | -20.0 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -20.0 |
| INHBA | inhibin, beta A | -20.0 |
| COL20A1 | collagen, type XX, alpha 1 | -20.0 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | -20.0 |
| SIX4 | SIX homeobox 4 | -20.0 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | -20.0 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -20.0 |
| CLEC3B | C-type lectin domain family 3, member B | -20.0 |
| ANXA11 | annexin A11 | -20.0 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -20.0 |
| FHOD1 | formin homology 2 domain containing 1 | -20.0 |
| DIAPH3 | diaphanous-related formin 3 | -20.0 |
| CPA4 | carboxypeptidase A4 | -20.0 |
| OLFML1 | olfactomedin-like 1 | -20.0 |
| KLF4 | Kruppel-like factor 4 (gut) | -20.0 |
| KLF2 | Kruppel-like factor 2 | -20.0 |
| AHR | aryl hydrocarbon receptor | -20.0 |
| EVA1A | eva-1 homolog A (C. elegans) | -20.0 |
| TNXB | tenascin XB | -20.0 |
| SYNC | syncoilin, intermediate filament protein | -20.0 |
| SMAD6 | SMAD family member 6 | -20.0 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -20.0 |
| THBD | thrombomodulin | -20.0 |
| DSP | desmoplakin | -20.0 |
| KCNA1 | potassium channel, voltage gated shaker related subfamily A, member 1 | -20.0 |
| MRGPRF | MAS-related GPR, member F | -20.0 |
| CLMP | CXADR-like membrane protein | -20.0 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | -20.0 |
| PLAC9 | placenta-specific 9 | -20.0 |
| STRA6 | stimulated by retinoic acid 6 | -20.0 |
| DOCK5 | dedicator of cytokinesis 5 | -20.0 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | -20.0 |
| KIAA1217 | KIAA1217 | -20.0 |
| CALB1 | calbindin 1, 28kDa | -20.0 |
| KCNK6 | potassium channel, two pore domain subfamily K, member 6 | -20.0 |
| SULF1 | sulfatase 1 | -20.0 |
| GXYLT2 | glucoside xylosyltransferase 2 | -20.0 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -20.0 |
| AQP1 | aquaporin 1 (Colton blood group) | -20.0 |
| TK1 | thymidine kinase 1, soluble | -20.0 |
| ACAN | aggrecan | -20.0 |
| WNT9A | wingless-type MMTV integration site family, member 9A | -20.0 |
| TNMD | tenomodulin | -20.0 |
| ANPEP | alanyl (membrane) aminopeptidase | -20.0 |
| LMCD1 | LIM and cysteine-rich domains 1 | -20.0 |
| SELENBP1 | selenium binding protein 1 | -20.0 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | -20.0 |
| PRRX2 | paired related homeobox 2 | -20.0 |
| TMEM30B | transmembrane protein 30B | -20.0 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -20.0 |
| MATN3 | matrilin 3 | -20.0 |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs | -20.0 |
| COL11A2 | collagen, type XI, alpha 2 | -20.0 |
| OMD | osteomodulin | -20.0 |
| ROR2 | receptor tyrosine kinase-like orphan receptor 2 | -20.0 |
| ROR1 | receptor tyrosine kinase-like orphan receptor 1 | -20.0 |
| PDGFRL | platelet-derived growth factor receptor-like | -20.0 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 | -20.0 |
| FZD8 | frizzled class receptor 8 | -20.0 |
| EN1 | engrailed homeobox 1 | -20.0 |
