Pertussis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A commensal bacterial infectious disease that results_in inflammation located_in respiratory tract, has_material_basis_in Bordetella pertussis, or has_material_basis_in Bordetella parapertussis, which produce toxins that paralyze the cilia of the respiratory epithelial cells. The infection is characterized by a prolonged, high-pitched, deeply indrawn breath (whoop). (Human Disease Ontology, DOID_1116)
External Link https://www.disgenet.org/browser/0/1/0/C0043167
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Genes

17 genes associated with the disease Pertussis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACOT7 acyl-CoA thioesterase 7
ACTBL2 actin, beta-like 2
ACTG1 actin gamma 1
ACTG2 actin, gamma 2, smooth muscle, enteric
CFH complement factor H
FHL5 four and a half LIM domains 5
IL17A interleukin 17A
MBTPS1 membrane-bound transcription factor peptidase, site 1
PGLYRP4 peptidoglycan recognition protein 4
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
POTEM POTE ankyrin domain family, member M
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC26A4 solute carrier family 26 (anion exchanger), member 4
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
UMOD uromodulin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor