| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pexidartinib (hydrochloride) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pexidartinib (hydrochloride)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TENM3 | teneurin transmembrane protein 3 | 0.164946 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.14344 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.115768 |
| ZNF608 | zinc finger protein 608 | 0.104311 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.103618 |
| NEBL | nebulette | 0.101752 |
| ATP11A | ATPase, class VI, type 11A | 0.0915117 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0857986 |
| FMNL2 | formin-like 2 | 0.0824098 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0483955 |
| FOXO3 | forkhead box O3 | 0.0473863 |
| FAT1 | FAT atypical cadherin 1 | 0.0467685 |
| DST | dystonin | 0.0444837 |
| COL5A2 | collagen, type V, alpha 2 | 0.0414423 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0391639 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0390441 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0386917 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0382786 |
| NUP58 | nucleoporin 58 | 0.0378607 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0376543 |
| YEATS2 | YEATS domain containing 2 | 0.0360767 |
| RAD51B | RAD51 paralog B | 0.0350298 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0345852 |
| SBF2 | SET binding factor 2 | 0.0336935 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.033499 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0333102 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0330356 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0329969 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0325126 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0316926 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0314838 |
| TBC1D32 | TBC1 domain family, member 32 | 0.03137 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0313441 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0303726 |
| ANKRD36 | ankyrin repeat domain 36 | 0.029838 |
| ATRN | attractin | 0.0285149 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0278917 |
| PCBP2 | poly(rC) binding protein 2 | 0.0271059 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.026737 |
| KIF1B | kinesin family member 1B | 0.0264556 |
| NGLY1 | N-glycanase 1 | 0.0262939 |
| VMP1 | vacuole membrane protein 1 | 0.0256029 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0249096 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0248653 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0248505 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0247131 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0246289 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0245416 |
| PTK2 | protein tyrosine kinase 2 | 0.0240792 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0240339 |
| ZNF292 | zinc finger protein 292 | 0.0240232 |
| FLNA | filamin A, alpha | 0.0239906 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0236494 |
| TUT4 | terminal uridylyl transferase 4 | 0.0236405 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0235945 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0229343 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0228716 |
| TBK1 | TANK-binding kinase 1 | 0.0227881 |
| EFNA5 | ephrin-A5 | 0.0227843 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0227389 |
| VEGFC | vascular endothelial growth factor C | 0.0225413 |
| CCNY | cyclin Y | 0.0222919 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0222348 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0220973 |
| SET | SET nuclear proto-oncogene | 0.0217653 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0216572 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.021424 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0213443 |
| PTCH1 | patched 1 | 0.021337 |
| SMAD4 | SMAD family member 4 | 0.0212716 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.020989 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.020979 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0209523 |
| ZNF638 | zinc finger protein 638 | 0.0207923 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0204751 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0203298 |
| RHOA | ras homolog family member A | 0.0202039 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0200558 |
| RTN4 | reticulon 4 | 0.0199806 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0199622 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.019949 |
| RPS2 | ribosomal protein S2 | 0.0197464 |
| PDE7A | phosphodiesterase 7A | 0.019671 |
| KLC1 | kinesin light chain 1 | 0.0195391 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0195236 |
| ARFGEF3 | ARFGEF family member 3 | 0.0195123 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0194754 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0193361 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0190987 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0190904 |
| HELZ | helicase with zinc finger | 0.0189572 |
| RNF150 | ring finger protein 150 | 0.0188071 |
| ZNF207 | zinc finger protein 207 | 0.0186721 |
| NBAS | neuroblastoma amplified sequence | 0.0186496 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0185232 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0184827 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0184071 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0183711 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0183579 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0181731 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.203815 |
| PTMA | prothymosin, alpha | -0.156534 |
| RPS6 | ribosomal protein S6 | -0.103376 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0996637 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.097535 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0964905 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0908129 |
| RPLP1 | ribosomal protein, large, P1 | -0.0860389 |
| RPS8 | ribosomal protein S8 | -0.0768756 |
| TMSB10 | thymosin beta 10 | -0.0761198 |
| ACTG1 | actin gamma 1 | -0.0759103 |
| RPS21 | ribosomal protein S21 | -0.0743753 |
| RPL34 | ribosomal protein L34 | -0.0732628 |
| RPS24 | ribosomal protein S24 | -0.0646889 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0631158 |
| RPLP2 | ribosomal protein, large, P2 | -0.0599315 |
| RPS19 | ribosomal protein S19 | -0.0598868 |
| RPL12 | ribosomal protein L12 | -0.0591134 |
| RPL32 | ribosomal protein L32 | -0.0586805 |
| HMGB1 | high mobility group box 1 | -0.0566653 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0562811 |
| RPL11 | ribosomal protein L11 | -0.0551779 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0542117 |
| H1-0 | H1.0 linker histone | -0.0526012 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0516901 |
| RPL23 | ribosomal protein L23 | -0.0515883 |
| RPS11 | ribosomal protein S11 | -0.0505555 |
| RPL19 | ribosomal protein L19 | -0.0504017 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0497378 |
| RPL31 | ribosomal protein L31 | -0.0492763 |
| RPS13 | ribosomal protein S13 | -0.0476666 |
| B2M | beta-2-microglobulin | -0.0474253 |
| RPS3 | ribosomal protein S3 | -0.0473019 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0472845 |
| RPL28 | ribosomal protein L28 | -0.0468632 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0461369 |
| RPS29 | ribosomal protein S29 | -0.0453464 |
| RPS27A | ribosomal protein S27a | -0.0448305 |
| RPS5 | ribosomal protein S5 | -0.0437473 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0433495 |
| RPL38 | ribosomal protein L38 | -0.0426758 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0426048 |
| RPL35A | ribosomal protein L35a | -0.0425336 |
| DEK | DEK proto-oncogene | -0.0424947 |
| RPS25 | ribosomal protein S25 | -0.0420682 |
| RPL9 | ribosomal protein L9 | -0.0412193 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0407989 |
| S100A9 | S100 calcium binding protein A9 | -0.0405344 |
| RPS15 | ribosomal protein S15 | -0.0405306 |
| RPL36 | ribosomal protein L36 | -0.0399868 |
| FTL | ferritin, light polypeptide | -0.0398445 |
| RPL26 | ribosomal protein L26 | -0.0397947 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0392873 |
| GNAS | GNAS complex locus | -0.0390433 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0389783 |
| RPS23 | ribosomal protein S23 | -0.0389552 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0384088 |
| RPS16 | ribosomal protein S16 | -0.038105 |
| RPS4X | ribosomal protein S4, X-linked | -0.0380155 |
| RPLP0 | ribosomal protein, large, P0 | -0.0354384 |
| RPL7A | ribosomal protein L7a | -0.0353978 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0351491 |
| VIM | vimentin | -0.0344107 |
| RPL5 | ribosomal protein L5 | -0.0341387 |
| RPL8 | ribosomal protein L8 | -0.0328673 |
| CADM2 | cell adhesion molecule 2 | -0.0328079 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0327228 |
| TPI1 | triosephosphate isomerase 1 | -0.0319685 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0317192 |
| RPL27A | ribosomal protein L27a | -0.0313328 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0312113 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0311469 |
| TUBB | tubulin, beta class I | -0.0302696 |
| CANX | calnexin | -0.0301632 |
| RPL35 | ribosomal protein L35 | -0.02998 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0294378 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0289505 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0284725 |
| SEPTIN7 | septin 7 | -0.0284044 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0283989 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0281559 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0280644 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0278279 |
| RRBP1 | ribosome binding protein 1 | -0.0278219 |
| MT2A | metallothionein 2A | -0.0277187 |
| RPL36A | ribosomal protein L36a | -0.0277079 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0276747 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0275914 |
| HMGB2 | high mobility group box 2 | -0.0275902 |
| FAM162A | family with sequence similarity 162, member A | -0.0275304 |
| RIGI | RNA sensor RIG-I | -0.0274261 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0273108 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0270483 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0270462 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0268868 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.0263471 |
| HLA-B | major histocompatibility complex, class I, B | -0.0261883 |
| PKM | pyruvate kinase, muscle | -0.0260379 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0257219 |
| CAVIN1 | caveolae associated protein 1 | -0.0254527 |
