| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pexidartinib (hydrochloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pexidartinib (hydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.139908 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0971901 |
| PRELID2 | PRELI domain containing 2 | 0.0790922 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0780737 |
| TMEM178B | transmembrane protein 178B | 0.0709311 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0597592 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0594548 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0579584 |
| ASPH | aspartate beta-hydroxylase | 0.0450953 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0413882 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0410232 |
| TNNC1 | troponin C type 1 (slow) | 0.0395323 |
| SETBP1 | SET binding protein 1 | 0.0386527 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.038467 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0378563 |
| EXOC4 | exocyst complex component 4 | 0.0367373 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0353377 |
| NAV2 | neuron navigator 2 | 0.034594 |
| PHF21A | PHD finger protein 21A | 0.0343721 |
| ATXN1 | ataxin 1 | 0.0330102 |
| PCDH7 | protocadherin 7 | 0.0327507 |
| RNF150 | ring finger protein 150 | 0.031638 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0316223 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0315523 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0273021 |
| APP | amyloid beta (A4) precursor protein | 0.0271327 |
| ARRDC3 | arrestin domain containing 3 | 0.0268818 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0268304 |
| FLNA | filamin A, alpha | 0.0267338 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0261729 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0258535 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0257519 |
| FRMD6 | FERM domain containing 6 | 0.0257308 |
| PDE10A | phosphodiesterase 10A | 0.0255062 |
| NEK7 | NIMA-related kinase 7 | 0.025235 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0247386 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0244581 |
| CD109 | CD109 molecule | 0.0243497 |
| RNF213 | ring finger protein 213 | 0.0236122 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0235337 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0231729 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.023159 |
| NAV1 | neuron navigator 1 | 0.0231342 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0229918 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0227959 |
| EFR3B | EFR3 homolog B (S. cerevisiae) | 0.0224189 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0222701 |
| RFX7 | regulatory factor X, 7 | 0.0218955 |
| MRTFA | myocardin related transcription factor A | 0.0213013 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0212825 |
| KLF10 | Kruppel-like factor 10 | 0.0211971 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0208553 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0208444 |
| MTERF1 | mitochondrial transcription termination factor 1 | 0.020771 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.019976 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0198978 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0196565 |
| AFAP1 | actin filament associated protein 1 | 0.0193284 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0193197 |
| STOM | stomatin | 0.0192221 |
| SMAD3 | SMAD family member 3 | 0.0191306 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0185934 |
| ANK2 | ankyrin 2, neuronal | 0.0185623 |
| EPHA3 | EPH receptor A3 | 0.0185217 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0185079 |
| VGLL4 | vestigial-like family member 4 | 0.018362 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0182367 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0179758 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0177765 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0176921 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.017662 |
| MEF2A | myocyte enhancer factor 2A | 0.017333 |
| FBXO7 | F-box protein 7 | 0.0169742 |
| METTL15 | methyltransferase like 15 | 0.0169282 |
| ACER3 | alkaline ceramidase 3 | 0.0168973 |
| STAMBPL1 | STAM binding protein-like 1 | 0.0165532 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0164792 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0164264 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0163216 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0162031 |
| MYOF | myoferlin | 0.0159827 |
| A2M | alpha-2-macroglobulin | 0.0158872 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0158281 |
| NRP2 | neuropilin 2 | 0.0157321 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0156516 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0155666 |
| CTTNBP2 | cortactin binding protein 2 | 0.0155397 |
| RPS2 | ribosomal protein S2 | 0.0155197 |
| RAD51B | RAD51 paralog B | 0.0154465 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0153968 |
| IFRD1 | interferon-related developmental regulator 1 | 0.015387 |
| RYBP | RING1 and YY1 binding protein | 0.0153531 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0152628 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0148771 |
| GPR137B | G protein-coupled receptor 137B | 0.0148657 |
| ZNF638 | zinc finger protein 638 | 0.014629 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.0146258 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0145709 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0145581 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0145457 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.231807 |
| VIM | vimentin | -0.17619 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.152963 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.107744 |
| TMSB10 | thymosin beta 10 | -0.106858 |
| HLA-B | major histocompatibility complex, class I, B | -0.105218 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.093586 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0910651 |
| GDF15 | growth differentiation factor 15 | -0.0868716 |
| VGF | VGF nerve growth factor inducible | -0.0868628 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0853056 |
| PTMA | prothymosin, alpha | -0.0806967 |
| ENO1 | enolase 1, (alpha) | -0.0791099 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0736424 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0695415 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0684342 |
| S100A6 | S100 calcium binding protein A6 | -0.06811 |
| CALD1 | caldesmon 1 | -0.0627391 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.058965 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0524164 |
| FMN1 | formin 1 | -0.0516622 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0501113 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0492266 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0475442 |
| EHBP1 | EH domain binding protein 1 | -0.0463768 |
| FTL | ferritin, light polypeptide | -0.0453051 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0430379 |
| ACTG1 | actin gamma 1 | -0.0425937 |
| TPI1 | triosephosphate isomerase 1 | -0.0422953 |
| EGR1 | early growth response 1 | -0.0422305 |
| DCT | dopachrome tautomerase | -0.0417083 |
| PTCHD4 | patched domain containing 4 | -0.0413656 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0393602 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0387693 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0386961 |
| IER3 | immediate early response 3 | -0.0380825 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0379417 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0379196 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0378605 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.037741 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0352915 |
| LMNA | lamin A/C | -0.0351302 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0345808 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0343939 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0337658 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0335075 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0332145 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0332 |
| S100A9 | S100 calcium binding protein A9 | -0.0330348 |
| CUX1 | cut-like homeobox 1 | -0.0330144 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0329169 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0327668 |
| PGK1 | phosphoglycerate kinase 1 | -0.0321245 |
| HLA-A | major histocompatibility complex, class I, A | -0.031985 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0314558 |
| CANX | calnexin | -0.0312835 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0307823 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0305506 |
| NDRG1 | N-myc downstream regulated 1 | -0.0304282 |
| PKM | pyruvate kinase, muscle | -0.0302133 |
| FAM162A | family with sequence similarity 162, member A | -0.0301882 |
| PTK2 | protein tyrosine kinase 2 | -0.0301007 |
| HMGA2 | high mobility group AT-hook 2 | -0.029871 |
| LAMB1 | laminin, beta 1 | -0.0296114 |
| TAGLN2 | transgelin 2 | -0.0291054 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0286877 |
| B2M | beta-2-microglobulin | -0.0286614 |
| RNF145 | ring finger protein 145 | -0.028427 |
| RPS6 | ribosomal protein S6 | -0.0280292 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0279739 |
| TMEM123 | transmembrane protein 123 | -0.0279642 |
| ZC3H7A | zinc finger CCCH-type containing 7A | -0.0276826 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0276078 |
| GNAS | GNAS complex locus | -0.027577 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0273366 |
| CD63 | CD63 molecule | -0.0270825 |
| SETD5 | SET domain containing 5 | -0.0269035 |
| FRMD5 | FERM domain containing 5 | -0.0267137 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0266404 |
| HMCN1 | hemicentin 1 | -0.0266179 |
| POTEF | POTE ankyrin domain family, member F | -0.0265717 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0265128 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0264088 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0261527 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0261215 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0258259 |
| RPLP1 | ribosomal protein, large, P1 | -0.0257787 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0256716 |
| COL1A2 | collagen, type I, alpha 2 | -0.0256542 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0249449 |
| MTDH | metadherin | -0.0248918 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0247891 |
| TPM4 | tropomyosin 4 | -0.0247683 |
| RPS8 | ribosomal protein S8 | -0.0247095 |
| VCL | vinculin | -0.024452 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.02439 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0243689 |
| MTPN | myotrophin | -0.0240754 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0239272 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0238468 |
