| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pexidartinib (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pexidartinib (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DTNA | dystrobrevin, alpha | 0.122486 |
| CD109 | CD109 molecule | 0.0748323 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0669234 |
| NDRG1 | N-myc downstream regulated 1 | 0.0587045 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0572096 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0554072 |
| GPC6 | glypican 6 | 0.0520991 |
| EFNA5 | ephrin-A5 | 0.0456068 |
| NUP58 | nucleoporin 58 | 0.0410549 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0381823 |
| FLNA | filamin A, alpha | 0.0380275 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0368654 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0362251 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0323954 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0314573 |
| SPAG9 | sperm associated antigen 9 | 0.0304583 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0290795 |
| ZNF292 | zinc finger protein 292 | 0.0290063 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.028541 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0284429 |
| MALT1 | MALT1 paracaspase | 0.026757 |
| PCBP2 | poly(rC) binding protein 2 | 0.024508 |
| RPS2 | ribosomal protein S2 | 0.0243569 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0242114 |
| KLF6 | Kruppel-like factor 6 | 0.0239879 |
| ATP13A3 | ATPase type 13A3 | 0.0235527 |
| MSN | moesin | 0.0229972 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0227136 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0226356 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0226272 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0220321 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.021619 |
| CDK19 | cyclin-dependent kinase 19 | 0.0213697 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0212631 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0195475 |
| PRELID2 | PRELI domain containing 2 | 0.0193062 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0191623 |
| KLF10 | Kruppel-like factor 10 | 0.0188815 |
| PEG10 | paternally expressed 10 | 0.0187414 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0187362 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0187233 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0186024 |
| CCNL1 | cyclin L1 | 0.0184441 |
| LSAMP | limbic system-associated membrane protein | 0.0184096 |
| CDC73 | cell division cycle 73 | 0.0180934 |
| NCKAP1 | NCK-associated protein 1 | 0.0178464 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0178405 |
| RARB | retinoic acid receptor, beta | 0.0177146 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0173768 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0171694 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0170412 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0168907 |
| PLIN2 | perilipin 2 | 0.0168905 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0168491 |
| HELZ | helicase with zinc finger | 0.0167325 |
| ARRDC3 | arrestin domain containing 3 | 0.0167007 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0165697 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0165441 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0164621 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.016436 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0164167 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0163127 |
| RUNX1 | runt-related transcription factor 1 | 0.0162903 |
| YEATS2 | YEATS domain containing 2 | 0.0162107 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0156012 |
| NRP2 | neuropilin 2 | 0.0156008 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0155062 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.0153573 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0152173 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0151492 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.015047 |
| SMAD3 | SMAD family member 3 | 0.0150143 |
| MYOF | myoferlin | 0.0149243 |
| CFAP20DC | CFAP20 domain containing | 0.0147782 |
| PRKCE | protein kinase C, epsilon | 0.01472 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0146764 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0146072 |
| WDR26 | WD repeat domain 26 | 0.0146061 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0145496 |
| NLGN1 | neuroligin 1 | 0.0141987 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0140983 |
| FRMD6 | FERM domain containing 6 | 0.014092 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0140562 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0139681 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0139571 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0139223 |
| FLNB | filamin B, beta | 0.0138315 |
| RBM26 | RNA binding motif protein 26 | 0.0137304 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0137206 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0136839 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0135033 |
| DST | dystonin | 0.0131401 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0131362 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0131092 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0131014 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0130552 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.013029 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0129378 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0129169 |
| LDHA | lactate dehydrogenase A | 0.0128405 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.284622 |
| VIM | vimentin | -0.217301 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.127685 |
| RPS6 | ribosomal protein S6 | -0.120715 |
| AHNAK | AHNAK nucleoprotein | -0.117176 |
| PTMA | prothymosin, alpha | -0.102763 |
| TMSB10 | thymosin beta 10 | -0.10173 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0867485 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.059493 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0559036 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0536597 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0528077 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0504843 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0504658 |
| RPLP1 | ribosomal protein, large, P1 | -0.0460285 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0453403 |
| NTM | neurotrimin | -0.0452006 |
| RPL8 | ribosomal protein L8 | -0.0429486 |
| RPL19 | ribosomal protein L19 | -0.040853 |
| RPL12 | ribosomal protein L12 | -0.0406948 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0406371 |
| RPLP2 | ribosomal protein, large, P2 | -0.0405895 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0389505 |
| RPS13 | ribosomal protein S13 | -0.0388322 |
| PTK2 | protein tyrosine kinase 2 | -0.0364555 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0364411 |
| CAVIN1 | caveolae associated protein 1 | -0.0363795 |
| EGR1 | early growth response 1 | -0.0359409 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0354431 |
| FTL | ferritin, light polypeptide | -0.0350688 |
| RPS27A | ribosomal protein S27a | -0.0350597 |
| RPS8 | ribosomal protein S8 | -0.0337412 |
| CDH13 | cadherin 13 | -0.0337067 |
| RPS25 | ribosomal protein S25 | -0.0330169 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0328087 |
| RPS21 | ribosomal protein S21 | -0.0323518 |
| RPL34 | ribosomal protein L34 | -0.0321323 |
| RPS24 | ribosomal protein S24 | -0.0317743 |
| FOXP1 | forkhead box P1 | -0.0316726 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0311838 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0304085 |
| TPM4 | tropomyosin 4 | -0.0299157 |
| PTCHD4 | patched domain containing 4 | -0.0291418 |
| RPS19 | ribosomal protein S19 | -0.0285133 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0282158 |
| RPL35A | ribosomal protein L35a | -0.0277971 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0275765 |
| ACTG1 | actin gamma 1 | -0.0275539 |
| PARD3 | par-3 family cell polarity regulator | -0.0272882 |
| RPL31 | ribosomal protein L31 | -0.026863 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.026711 |
| RPL38 | ribosomal protein L38 | -0.0266555 |
| CALD1 | caldesmon 1 | -0.0264458 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0263254 |
| CDK6 | cyclin-dependent kinase 6 | -0.0263159 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.02606 |
| RPL36A | ribosomal protein L36a | -0.026049 |
| H1-0 | H1.0 linker histone | -0.0258353 |
| RPS23 | ribosomal protein S23 | -0.0254287 |
| RPL32 | ribosomal protein L32 | -0.0253626 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0248903 |
| RPLP0 | ribosomal protein, large, P0 | -0.0246549 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0234753 |
| RIGI | RNA sensor RIG-I | -0.023176 |
| RPL11 | ribosomal protein L11 | -0.0231253 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.022971 |
| KYNU | kynureninase | -0.0227156 |
| YBX3 | Y box binding protein 3 | -0.0225565 |
| ZNF804A | zinc finger protein 804A | -0.022504 |
| INTS6 | integrator complex subunit 6 | -0.022156 |
| IER3 | immediate early response 3 | -0.0217615 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.021523 |
| RPL36 | ribosomal protein L36 | -0.0214682 |
| RPL23 | ribosomal protein L23 | -0.0214355 |
| SP100 | SP100 nuclear antigen | -0.0211984 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0211208 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0210542 |
| ASTN2 | astrotactin 2 | -0.0208863 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.020707 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0205725 |
| RPL27A | ribosomal protein L27a | -0.0204036 |
| CUX1 | cut-like homeobox 1 | -0.0202171 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | -0.0199878 |
| RPL7A | ribosomal protein L7a | -0.0198085 |
| MYO10 | myosin X | -0.0196108 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0193623 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0192344 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.019187 |
| RPS14 | ribosomal protein S14 | -0.0190715 |
| MT2A | metallothionein 2A | -0.0190331 |
| RPS16 | ribosomal protein S16 | -0.0188782 |
| RPL26 | ribosomal protein L26 | -0.0187112 |
| RPS15 | ribosomal protein S15 | -0.0186188 |
| RPS29 | ribosomal protein S29 | -0.0184307 |
| RPL35 | ribosomal protein L35 | -0.0183782 |
| FN1 | fibronectin 1 | -0.0183419 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0182905 |
| RPS11 | ribosomal protein S11 | -0.0182686 |
| KIAA1217 | KIAA1217 | -0.0182377 |
| RPS10 | ribosomal protein S10 | -0.0182327 |
