| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pexidartinib (hydrochloride) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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72 genes differentially expressed following the Pexidartinib (hydrochloride)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLIT2 | slit homolog 2 (Drosophila) | 0.27394 |
| PGK1 | phosphoglycerate kinase 1 | 0.173137 |
| EFNA5 | ephrin-A5 | 0.13653 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.113346 |
| TENM3 | teneurin transmembrane protein 3 | 0.111673 |
| ACTN4 | actinin, alpha 4 | 0.102984 |
| RPL26 | ribosomal protein L26 | 0.102197 |
| PARD3 | par-3 family cell polarity regulator | 0.096041 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0940491 |
| LMO7 | LIM domain 7 | 0.0915615 |
| RUNX1 | runt-related transcription factor 1 | 0.0845321 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0834876 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.079901 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0755258 |
| ASPH | aspartate beta-hydroxylase | 0.0715243 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0693771 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0614816 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0593348 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0559801 |
| CD44 | CD44 molecule (Indian blood group) | 0.0509375 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0475468 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0432577 |
| FLNB | filamin B, beta | 0.0392694 |
| ACTG1 | actin gamma 1 | 0.0381881 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.029687 |
| OGA | O-GlcNAcase | 0.0268591 |
| FAT1 | FAT atypical cadherin 1 | 0.0267071 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0259369 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0251054 |
| CDH13 | cadherin 13 | 0.0214813 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0207852 |
| RPS6 | ribosomal protein S6 | 0.0180056 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0139316 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0120587 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00813986 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.00622776 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0037946 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.42231 |
| VIM | vimentin | -0.342172 |
| FN1 | fibronectin 1 | -0.218656 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.202815 |
| PTMA | prothymosin, alpha | -0.17443 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.148102 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.100356 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0844822 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0794571 |
| INHBA | inhibin, beta A | -0.0794083 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0707188 |
| MYOF | myoferlin | -0.0667171 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0546615 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0541359 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0520301 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0492937 |
| PKM | pyruvate kinase, muscle | -0.0484354 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0460407 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0447247 |
| TMSB10 | thymosin beta 10 | -0.0444706 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0424283 |
| NDRG1 | N-myc downstream regulated 1 | -0.0405671 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0394301 |
| PTK2 | protein tyrosine kinase 2 | -0.0386515 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0383466 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0376372 |
| EGFR | epidermal growth factor receptor | -0.035483 |
| FTL | ferritin, light polypeptide | -0.0300849 |
| DST | dystonin | -0.0281071 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0255534 |
| PDE10A | phosphodiesterase 10A | -0.0154539 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0109487 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.00150789 |
| RPL35A | ribosomal protein L35a | -8.12322E-4 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -4.43711E-4 |
