| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pexidartinib (hydrochloride) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pexidartinib (hydrochloride)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.214709 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.173871 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.143355 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.133739 |
| VIM | vimentin | 0.0972068 |
| CENPF | centromere protein F, 350/400kDa | 0.0862871 |
| NDRG1 | N-myc downstream regulated 1 | 0.0844509 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0838482 |
| ASPH | aspartate beta-hydroxylase | 0.0827269 |
| TPR | translocated promoter region, nuclear basket protein | 0.0803193 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0779309 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0726093 |
| FN1 | fibronectin 1 | 0.0715674 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.06955 |
| MT2A | metallothionein 2A | 0.0671852 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0663164 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0659036 |
| AHR | aryl hydrocarbon receptor | 0.0645479 |
| RPS12 | ribosomal protein S12 | 0.0584407 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0583226 |
| TXNIP | thioredoxin interacting protein | 0.058061 |
| RACK1 | receptor for activated C kinase 1 | 0.0577579 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0573625 |
| TXNRD1 | thioredoxin reductase 1 | 0.0565513 |
| OSMR | oncostatin M receptor | 0.0563118 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0555177 |
| ZNF292 | zinc finger protein 292 | 0.0549225 |
| CD44 | CD44 molecule (Indian blood group) | 0.0549182 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0545787 |
| EREG | epiregulin | 0.0541392 |
| PRELID2 | PRELI domain containing 2 | 0.0515626 |
| MKI67 | marker of proliferation Ki-67 | 0.0509674 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0502101 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0495241 |
| FLNA | filamin A, alpha | 0.0483041 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0482388 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0478525 |
| NRP1 | neuropilin 1 | 0.0476916 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0471631 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0469764 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0463896 |
| LDHA | lactate dehydrogenase A | 0.0458994 |
| DST | dystonin | 0.0437922 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0428576 |
| PELO | pelota homolog (Drosophila) | 0.0428297 |
| TMEM156 | transmembrane protein 156 | 0.0419573 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0419039 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.041717 |
| CLTC | clathrin, heavy chain (Hc) | 0.0410444 |
| ETV6 | ets variant 6 | 0.0406944 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0402839 |
| FOXP1 | forkhead box P1 | 0.0400116 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0399099 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0398253 |
| RNF213 | ring finger protein 213 | 0.0390914 |
| RPS2 | ribosomal protein S2 | 0.0390789 |
| RPL26 | ribosomal protein L26 | 0.0386082 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0383985 |
| KIF5B | kinesin family member 5B | 0.0381974 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0380255 |
| ATXN1 | ataxin 1 | 0.0377677 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0366014 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.035905 |
| SMAD3 | SMAD family member 3 | 0.0356671 |
| CEP350 | centrosomal protein 350kDa | 0.0356305 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0355559 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.035469 |
| CAB39 | calcium binding protein 39 | 0.0354045 |
| GOLGA4 | golgin A4 | 0.0352844 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0348742 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.03419 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0337886 |
| HELZ | helicase with zinc finger | 0.0337189 |
| GLIS3 | GLIS family zinc finger 3 | 0.0328777 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.032043 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0319426 |
| SFXN1 | sideroflexin 1 | 0.0319028 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0318752 |
| PTK2 | protein tyrosine kinase 2 | 0.0318384 |
| ARRDC3 | arrestin domain containing 3 | 0.0317756 |
| SLTM | SAFB-like, transcription modulator | 0.0310001 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0308017 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0307827 |
| SPAG9 | sperm associated antigen 9 | 0.0306365 |
| TPI1 | triosephosphate isomerase 1 | 0.0303797 |
| ETNK1 | ethanolamine kinase 1 | 0.0303621 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0302708 |
| ETV1 | ets variant 1 | 0.0301332 |
| CANX | calnexin | 0.0301017 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0300764 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0299372 |
| TMF1 | TATA element modulatory factor 1 | 0.0297977 |
| RPL7 | ribosomal protein L7 | 0.0297285 |
| RBM39 | RNA binding motif protein 39 | 0.0293665 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0292851 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0291648 |
| MAP1B | microtubule-associated protein 1B | 0.0290938 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.029033 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0290072 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0289629 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.16828 |
| HMGA2 | high mobility group AT-hook 2 | -0.102163 |
| PTMA | prothymosin, alpha | -0.0664178 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.062309 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.048018 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0441404 |
| INTS6 | integrator complex subunit 6 | -0.0438598 |
| CADM1 | cell adhesion molecule 1 | -0.0434125 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0433645 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0421984 |
| AEBP2 | AE binding protein 2 | -0.0367267 |
| RAI14 | retinoic acid induced 14 | -0.0355172 |
| TMSB10 | thymosin beta 10 | -0.0331145 |
| AHNAK | AHNAK nucleoprotein | -0.0302054 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0295881 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0295723 |
| TENM4 | teneurin transmembrane protein 4 | -0.0291935 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0286925 |
| TMEM165 | transmembrane protein 165 | -0.0279643 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0269603 |
| MTSS1 | metastasis suppressor 1 | -0.0234649 |
| CDK13 | cyclin-dependent kinase 13 | -0.0232121 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0231036 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0229905 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0225565 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0221382 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0218579 |
| CLIC4 | chloride intracellular channel 4 | -0.0216012 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0214182 |
| MCL1 | myeloid cell leukemia 1 | -0.0211628 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0204745 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0196525 |
| PCNX4 | pecanex 4 | -0.0191361 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0188421 |
| LRRC23 | leucine rich repeat containing 23 | -0.0188169 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0182358 |
| ABR | active BCR-related | -0.0180042 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.017974 |
| MLPH | melanophilin | -0.0174666 |
| AHI1 | Abelson helper integration site 1 | -0.0174485 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0173987 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0170869 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0169111 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0168412 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0167788 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0166832 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0163447 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0159455 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0155279 |
| WASF2 | WAS protein family, member 2 | -0.0154899 |
| SERF2 | small EDRK-rich factor 2 | -0.0154774 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0154393 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0153621 |
| IL6 | interleukin 6 | -0.0153054 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0151484 |
| PALLD | palladin, cytoskeletal associated protein | -0.0150687 |
| NXN | nucleoredoxin | -0.0150441 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0148207 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0146762 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.014569 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0143296 |
| PLIN2 | perilipin 2 | -0.0142193 |
| POU2F2 | POU class 2 homeobox 2 | -0.0141234 |
| ACTG1 | actin gamma 1 | -0.0139756 |
| FUS | FUS RNA binding protein | -0.0139696 |
| FBN1 | fibrillin 1 | -0.0138802 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | -0.0137063 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0134261 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0133752 |
| UBN2 | ubinuclein 2 | -0.0133633 |
| CTSD | cathepsin D | -0.0133339 |
| HLA-B | major histocompatibility complex, class I, B | -0.0132378 |
| SCFD2 | sec1 family domain containing 2 | -0.0131767 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0130438 |
| DGKH | diacylglycerol kinase, eta | -0.0129948 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0129084 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0127604 |
| ADIPOR2 | adiponectin receptor 2 | -0.0125831 |
| WTAP | Wilms tumor 1 associated protein | -0.0125181 |
| S100A9 | S100 calcium binding protein A9 | -0.0125122 |
| CHGB | chromogranin B | -0.0124104 |
| SETD5 | SET domain containing 5 | -0.0123132 |
| BMERB1 | bMERB domain containing 1 | -0.0122788 |
| HIP1 | huntingtin interacting protein 1 | -0.0122493 |
| UBAP2 | ubiquitin associated protein 2 | -0.0121189 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0121187 |
| CP | ceruloplasmin (ferroxidase) | -0.0120986 |
| TBCA | tubulin folding cofactor A | -0.0120916 |
| MCU | mitochondrial calcium uniporter | -0.0120565 |
| GPR75-ASB3 | GPR75-ASB3 readthrough | -0.0119923 |
| TCIM | transcriptional and immune response regulator | -0.0119815 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0117609 |
| NPAS1 | neuronal PAS domain protein 1 | -0.0114453 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0113184 |
| RPS25 | ribosomal protein S25 | -0.0113115 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.0112597 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0112189 |
| QKI | QKI, KH domain containing, RNA binding | -0.0112073 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0111783 |
| TSLIG3A | tRNA splicing ligase complex subunit 3A | -0.0111431 |
