Phagosome Gene Set

Dataset KEGG Pathways 2026
Category structural or functional annotations
Type pathway
Description Phagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is formed when the specific receptors on the phagocyte surface recognize ligands on the particle surface. After formation, nascent phagosomes progressively acquire digestive characteristics. This maturation of phagosomes involves regulated interaction with the other membrane organelles, including recycling endosomes, late endosomes and lysosomes. The fusion of phagosomes and lysosomes releases toxic products that kill most bacteria and degrade them into fragments. However, some bacteria have strategies to escape the bactericidal mechanisms associated with phagocytosis and survive within host phagocytes. (Kyoto Encyclopedia of Genes and Genomes, hsa04145)
External Link https://www.kegg.jp/entry/hsa04145
Similar Terms
Downloads & Tools

Genes

151 proteins participating in the Phagosome pathway from the KEGG Pathways 2026 dataset.

Symbol Name
ACTG1 actin gamma 1
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
ATP6V1G3 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
C1R complement component 1, r subcomponent
C3 complement component 3
CALR calreticulin
CANX calnexin
CD209 CD209 molecule
CD36 CD36 molecule (thrombospondin receptor)
CLEC4M C-type lectin domain family 4, member M
CLEC7A C-type lectin domain family 7, member A
COLEC11 collectin sub-family member 11
COLEC12 collectin sub-family member 12
COMP cartilage oligomeric matrix protein
CORO1A coronin, actin binding protein, 1A
CTSL cathepsin L
CTSS cathepsin S
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EEA1 early endosome antigen 1
FCAR Fc fragment of IgA receptor
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB5 integrin, beta 5
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
LOC102724971 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LOC124905743 low affinity immunoglobulin gamma Fc region receptor III-B
M6PR mannose-6-phosphate receptor (cation dependent)
MARCO macrophage receptor with collagenous structure
MBL2 mannose-binding lectin (protein C) 2, soluble
MPO myeloperoxidase
MRC1 mannose receptor, C type 1
MRC2 mannose receptor, C type 2
MSR1 macrophage scavenger receptor 1
NANOS1 nanos homolog 1 (Drosophila)
NCF1 neutrophil cytosolic factor 1
NCF2 neutrophil cytosolic factor 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIKFYVE phosphoinositide kinase, FYVE finger containing
PLA2R1 phospholipase A2 receptor 1, 180kDa
POTEF POTE ankyrin domain family, member F
PRICKLE1 prickle homolog 1 (Drosophila)
RAB5A RAB5A, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAB7B RAB7B, member RAS oncogene family
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SCARB1 scavenger receptor class B, member 1
SEC14L2 SEC14-like 2 (S. cerevisiae)
SEC14L3 SEC14-like 3 (S. cerevisiae)
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEC61B Sec61 beta subunit
SEC61G Sec61 gamma subunit
SFTPA1 surfactant protein A1
SFTPA2 surfactant protein A2
SFTPD surfactant protein D
STX12 syntaxin 12
STX18 syntaxin 18
STX7 syntaxin 7
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TFRC transferrin receptor
THBS1 thrombospondin 1
THBS2 thrombospondin 2
THBS3 thrombospondin 3
THBS4 thrombospondin 4
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TUBA1A tubulin, alpha 1a
TUBA1B tubulin, alpha 1b
TUBA1C tubulin, alpha 1c
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
TUBA3E tubulin, alpha 3e
TUBA4A tubulin, alpha 4a
TUBA8 tubulin, alpha 8
TUBAL3 tubulin, alpha-like 3
TUBB tubulin, beta class I
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TUBB3 tubulin, beta 3 class III
TUBB4A tubulin, beta 4A class IVa
TUBB4B tubulin, beta 4B class IVb
TUBB6 tubulin, beta 6 class V
TUBB8 tubulin, beta 8 class VIII
TUBB8B tubulin beta 8B
VAMP3 vesicle-associated membrane protein 3