Pharyngitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description An upper respiratory tract disease involving inflammation of the throat or pharynx resulting from bacterial, viral, fungal infections or irritants like pollutants or chemical substances and smoking. The infection is often referred to as sore throat. The symptoms include pain during swallowing, enlarged tonsils coated with a white discharge, runny nose, cough and slight fever. (Human Disease Ontology, DOID_2275)
Similar Terms
Downloads & Tools

Genes

306 genes co-occuring with the disease Pharyngitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
MYOM2 myomesin 2 3.255
CRP C-reactive protein, pentraxin-related 2.823
MEFV Mediterranean fever 2.643
MVK mevalonate kinase 2.552
IL1B interleukin 1, beta 2.517
TNF tumor necrosis factor 2.503
IL6 interleukin 6 2.483
CD4 CD4 molecule 2.382
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.318
NLRP3 NLR family, pyrin domain containing 3 2.317
IFNG interferon, gamma 2.311
CD8A CD8a molecule 2.224
CXCL8 chemokine (C-X-C motif) ligand 8 2.217
IL1A interleukin 1, alpha 2.175
IL10 interleukin 10 2.123
ACE2 angiotensin I converting enzyme 2 2.119
IL17A interleukin 17A 2.118
ALB albumin 2.105
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.095
SPEG SPEG complex locus 2.064
SPAG7 sperm associated antigen 7 2.032
IL2 interleukin 2 2.025
IL4 interleukin 4 2.021
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 2.017
ERVW-1 endogenous retrovirus group W, member 1 2.015
ERV3-1 endogenous retrovirus group 3, member 1 2.001
ERVFRD-1 endogenous retrovirus group FRD, member 1 2.0
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.988
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.985
TLR4 toll-like receptor 4 1.977
IL18 interleukin 18 1.952
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 1.948
CAMP cathelicidin antimicrobial peptide 1.945
IL5 interleukin 5 1.945
IL1RN interleukin 1 receptor antagonist 1.938
TLR2 toll-like receptor 2 1.904
IFNA1 interferon, alpha 1 1.873
CSF3 colony stimulating factor 3 (granulocyte) 1.869
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 1.862
FN1 fibronectin 1 1.847
NLRP12 NLR family, pyrin domain containing 12 1.842
IFNB1 interferon, beta 1, fibroblast 1.838
PLG plasminogen 1.827
CXCL10 chemokine (C-X-C motif) ligand 10 1.826
ACE angiotensin I converting enzyme 1.822
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.82
C3 complement component 3 1.796
IL13 interleukin 13 1.784
MYH14 myosin, heavy chain 14, non-muscle 1.746
MYD88 myeloid differentiation primary response 88 1.744
CARD8 caspase recruitment domain family, member 8 1.736
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.724
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.721
NOD2 nucleotide-binding oligomerization domain containing 2 1.717
CARD14 caspase recruitment domain family, member 14 1.715
CCL2 chemokine (C-C motif) ligand 2 1.709
CKMT1B creatine kinase, mitochondrial 1B 1.707
CKM creatine kinase, muscle 1.707
IL36RN interleukin 36 receptor antagonist 1.706
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.705
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.702
CKB creatine kinase, brain 1.701
F3 coagulation factor III (thromboplastin, tissue factor) 1.693
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.682
IL36R interleukin 36 receptor 1.681
F2 coagulation factor II (thrombin) 1.665
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.661
MPO myeloperoxidase 1.654
TLR9 toll-like receptor 9 1.65
CD19 CD19 molecule 1.649
CPN1 carboxypeptidase N, polypeptide 1 1.643
ELANE elastase, neutrophil expressed 1.642
LPIN2 lipin 2 1.633
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.63
TMPRSS2 transmembrane protease, serine 2 1.627
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.612
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 1.611
LTF lactotransferrin 1.61
TGFB1 transforming growth factor, beta 1 1.59
HLA-B major histocompatibility complex, class I, B 1.585
TLR3 toll-like receptor 3 1.56
IFNA2 interferon, alpha 2 1.56
CD46 CD46 molecule, complement regulatory protein 1.554
ICAM1 intercellular adhesion molecule 1 1.541
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.536
INS insulin 1.53
HLA-C major histocompatibility complex, class I, C 1.523
IFNA17 interferon, alpha 17 1.522
KNG1 kininogen 1 1.522
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.52
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 1.514
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.514
TLR7 toll-like receptor 7 1.505
POM121 POM121 transmembrane nucleoporin 1.499
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.496
IRF3 interferon regulatory factor 3 1.487
HOXD13 homeobox D13 1.484
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.473
NLRC4 NLR family, CARD domain containing 4 1.472
JUN jun proto-oncogene 1.461
IL22 interleukin 22 1.46
CCL5 chemokine (C-C motif) ligand 5 1.459
PXDNL peroxidasin-like 1.456
PXDN peroxidasin 1.454
C4B complement component 4B (Chido blood group) 1.448
CCL3 chemokine (C-C motif) ligand 3 1.444
IL7 interleukin 7 1.443
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.44
SH2D1A SH2 domain containing 1A 1.44
PRF1 perforin 1 (pore forming protein) 1.44
IL17F interleukin 17F 1.433
IFNA6 interferon, alpha 6 1.433
PRTN3 proteinase 3 1.432
IFNA4 interferon, alpha 4 1.428
IFNA14 interferon, alpha 14 1.426
IFNA10 interferon, alpha 10 1.426
IFNA21 interferon, alpha 21 1.426
IFNA16 interferon, alpha 16 1.419
IFNA7 interferon, alpha 7 1.419
IFNA8 interferon, alpha 8 1.418
IFNA5 interferon, alpha 5 1.416
IFNA13 interferon, alpha 13 1.415
CD27 CD27 molecule 1.414
VCAM1 vascular cell adhesion molecule 1 1.412
DEFB4A defensin, beta 4A 1.408
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.401
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 1.4
SAA2 serum amyloid A2 1.396
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.395
BCL2 B-cell CLL/lymphoma 2 1.392
C4A complement component 4A (Rodgers blood group) 1.391
IL15 interleukin 15 1.388
STAT1 signal transducer and activator of transcription 1, 91kDa 1.386
SAA1 serum amyloid A1 1.386
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.384
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.384
HP haptoglobin 1.381
CD40 CD40 molecule, TNF receptor superfamily member 5 1.38
IFIH1 interferon induced with helicase C domain 1 1.378
CCL4 chemokine (C-C motif) ligand 4 1.368
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.366
CXCL9 chemokine (C-X-C motif) ligand 9 1.36
MBL2 mannose-binding lectin (protein C) 2, soluble 1.359
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.359
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.353
DEFB112 defensin, beta 112 1.35
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.348
MX1 MX dynamin-like GTPase 1 1.345
AZU1 azurocidin 1 1.345
ACTB actin, beta 1.341
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.336
IL1R1 interleukin 1 receptor, type I 1.332
LTA lymphotoxin alpha 1.326
LGALS3 lectin, galactoside-binding, soluble, 3 1.314
TLR1 toll-like receptor 1 1.313
NCAM1 neural cell adhesion molecule 1 1.306
IL9 interleukin 9 1.305
AIM2 absent in melanoma 2 1.3
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 1.285
DMBT1 deleted in malignant brain tumors 1 1.28
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.278
ALPK1 alpha-kinase 1 1.278
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.276
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.273
JAK1 Janus kinase 1 1.272
PYCARD PYD and CARD domain containing 1.271
CALCOCO2 calcium binding and coiled-coil domain 2 1.268
NLRP1 NLR family, pyrin domain containing 1 1.266
CD40LG CD40 ligand 1.266
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.264
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.263
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 1.261
DPP4 dipeptidyl-peptidase 4 1.258
CCL11 chemokine (C-C motif) ligand 11 1.253
CD80 CD80 molecule 1.25
TLR6 toll-like receptor 6 1.248
NPPB natriuretic peptide B 1.248
ITPKC inositol-trisphosphate 3-kinase C 1.246
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.244
CFP complement factor properdin 1.237
TLR5 toll-like receptor 5 1.236
FBXO3 F-box protein 3 1.233
MB myoglobin 1.231
TYK2 tyrosine kinase 2 1.23
TP53 tumor protein p53 1.222
FOXP3 forkhead box P3 1.221
SH2D3A SH2 domain containing 3A 1.218
MMP9 matrix metallopeptidase 9 1.217
TLR8 toll-like receptor 8 1.214
LIAS lipoic acid synthetase 1.209
IL33 interleukin 33 1.206
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.203
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 1.201
OTULIN OTU deubiquitinase with linear linkage specificity 1.2
CCL20 chemokine (C-C motif) ligand 20 1.196
REN renin 1.193
RNASE3 ribonuclease, RNase A family, 3 1.193
PRPH2 peripherin 2 (retinal degeneration, slow) 1.187
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.187
ADA2 adenosine deaminase 2 1.183
MAPK3 mitogen-activated protein kinase 3 1.181
LAMP1 lysosomal-associated membrane protein 1 1.179
AIF1L allograft inflammatory factor 1-like 1.177
PPARG peroxisome proliferator-activated receptor gamma 1.177
CD38 CD38 molecule 1.176
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.175
CD2 CD2 molecule 1.174
WDR88 WD repeat domain 88 1.171
HPR haptoglobin-related protein 1.171
TG thyroglobulin 1.171
NOD1 nucleotide-binding oligomerization domain containing 1 1.169
S100A12 S100 calcium binding protein A12 1.169
HRH2 histamine receptor H2 1.167
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.166
EGFR epidermal growth factor receptor 1.163
VTN vitronectin 1.163
TAC1 tachykinin, precursor 1 1.163
ENO1 enolase 1, (alpha) 1.162
HAX1 HCLS1 associated protein X-1 1.162
CD86 CD86 molecule 1.161
GP2 glycoprotein 2 (zymogen granule membrane) 1.16
JAK2 Janus kinase 2 1.155
HLA-A major histocompatibility complex, class I, A 1.153
IL17RA interleukin 17 receptor A 1.153
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.144
CYCS cytochrome c, somatic 1.142
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 1.14
PTPRC protein tyrosine phosphatase, receptor type, C 1.139
FURIN furin (paired basic amino acid cleaving enzyme) 1.138
IRAK4 interleukin-1 receptor-associated kinase 4 1.136
CD68 CD68 molecule 1.136
CFH complement factor H 1.135
STING1 stimulator of interferon response cGAMP interactor 1 1.134
SOCS1 suppressor of cytokine signaling 1 1.133
SELE selectin E 1.133
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.132
IL3 interleukin 3 1.129
TSLP thymic stromal lymphopoietin 1.127
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 1.123
IRF7 interferon regulatory factor 7 1.116
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.109
GAP43 growth associated protein 43 1.108
UNC13D unc-13 homolog D (C. elegans) 1.108
GPX2 glutathione peroxidase 2 1.107
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 1.107
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 1.104
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 1.098
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1 1.098
PDE4A phosphodiesterase 4A, cAMP-specific 1.097
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.094
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.094
FIMP1 fertilization-influencing membrane protein 1 1.093
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 1.09
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 1.083
CXCL11 chemokine (C-X-C motif) ligand 11 1.082
IL23R interleukin 23 receptor 1.08
GPX5 glutathione peroxidase 5 1.074
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.07
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.069
GPX6 glutathione peroxidase 6 1.063
GPX8 glutathione peroxidase 8 (putative) 1.062
GPX7 glutathione peroxidase 7 1.059
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.058
TPO thyroid peroxidase 1.057
ADAM17 ADAM metallopeptidase domain 17 1.057
GTPBP1 GTP binding protein 1 1.056
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.056
SH2D3C SH2 domain containing 3C 1.054
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.053
GPX3 glutathione peroxidase 3 1.052
IL4R interleukin 4 receptor 1.051
GYPC glycophorin C (Gerbich blood group) 1.051
IL5RA interleukin 5 receptor, alpha 1.051
ALOX5 arachidonate 5-lipoxygenase 1.048
NBR1 neighbor of BRCA1 gene 1 1.047
CCL26 chemokine (C-C motif) ligand 26 1.045
CD1D CD1d molecule 1.044
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.039
BTK Bruton agammaglobulinemia tyrosine kinase 1.038
CCR7 chemokine (C-C motif) receptor 7 1.037
GALP galanin-like peptide 1.035
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 1.035
FASLG Fas ligand (TNF superfamily, member 6) 1.034
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.034
BAX BCL2-associated X protein 1.031
ARX aristaless related homeobox 1.03
MOG myelin oligodendrocyte glycoprotein 1.03
INSRR insulin receptor-related receptor 1.029
CD28 CD28 molecule 1.024
STAT2 signal transducer and activator of transcription 2, 113kDa 1.022
HSPE1 heat shock 10kDa protein 1 1.022
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.022
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.021
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.021
CXCR3 chemokine (C-X-C motif) receptor 3 1.019
WDR1 WD repeat domain 1 1.017
SELL selectin L 1.015
LGALS8 lectin, galactoside-binding, soluble, 8 1.014
CD44 CD44 molecule (Indian blood group) 1.014
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.014
CD1A CD1a molecule 1.014
HTRA1 HtrA serine peptidase 1 1.009
GAST gastrin 1.008
B2M beta-2-microglobulin 1.006
CD5 CD5 molecule 1.003
IRAK1 interleukin-1 receptor-associated kinase 1 1.001