| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenylephrine (hydrochloride)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.299089 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.151678 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.129192 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.120491 |
| TPM4 | tropomyosin 4 | 0.118719 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.117054 |
| PLAT | plasminogen activator, tissue | 0.107664 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0882118 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0846911 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0815294 |
| COL3A1 | collagen, type III, alpha 1 | 0.0774077 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.072974 |
| AHNAK | AHNAK nucleoprotein | 0.0723466 |
| B2M | beta-2-microglobulin | 0.0637428 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0626079 |
| FBN1 | fibrillin 1 | 0.0612075 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0609341 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0598592 |
| TPM3 | tropomyosin 3 | 0.0598285 |
| ATP13A3 | ATPase type 13A3 | 0.0588263 |
| FLNB | filamin B, beta | 0.0578214 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0559778 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0514872 |
| GPC6 | glypican 6 | 0.05011 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0476585 |
| CDH13 | cadherin 13 | 0.0475428 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0470487 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0470029 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0467962 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0454921 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0452151 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0451653 |
| USP34 | ubiquitin specific peptidase 34 | 0.0432529 |
| CANX | calnexin | 0.043251 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0430162 |
| POTEF | POTE ankyrin domain family, member F | 0.0419519 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0416577 |
| KIF5B | kinesin family member 5B | 0.0410016 |
| INSIG2 | insulin induced gene 2 | 0.040474 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0402955 |
| STC1 | stanniocalcin 1 | 0.0399969 |
| PTMA | prothymosin, alpha | 0.0395519 |
| MYOF | myoferlin | 0.0395325 |
| CENPF | centromere protein F, 350/400kDa | 0.0390692 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0390216 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0386301 |
| SBF2 | SET binding factor 2 | 0.0383841 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0383309 |
| XPO1 | exportin 1 | 0.0380523 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0378148 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0377268 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.037514 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0369675 |
| HELZ | helicase with zinc finger | 0.0368368 |
| MSN | moesin | 0.0362805 |
| ARRDC3 | arrestin domain containing 3 | 0.0356543 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.035317 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0352281 |
| PGK1 | phosphoglycerate kinase 1 | 0.0351302 |
| SETD5 | SET domain containing 5 | 0.0348699 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0346884 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0344674 |
| GOLGA4 | golgin A4 | 0.0342403 |
| SEPTIN2 | septin 2 | 0.0340675 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0339 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.033766 |
| RAI1 | retinoic acid induced 1 | 0.0332086 |
| ERBIN | erbb2 interacting protein | 0.0329233 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0325871 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0325468 |
| CD109 | CD109 molecule | 0.0322133 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0321508 |
| CD99 | CD99 molecule | 0.0320901 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0320175 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0313753 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.031183 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0308191 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0307049 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0306076 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0304002 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0303994 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0300141 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0299856 |
| ENO1 | enolase 1, (alpha) | 0.0298803 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0296884 |
| MATR3 | matrin 3 | 0.029617 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0295541 |
| CALR | calreticulin | 0.0294935 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0290668 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0288685 |
| AFDN | afadin, adherens junction formation factor | 0.0288386 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0287816 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.028711 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0286641 |
| PRELID2 | PRELI domain containing 2 | 0.028011 |
| CDK19 | cyclin-dependent kinase 19 | 0.0279681 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0278404 |
| LOXL2 | lysyl oxidase-like 2 | 0.0274675 |
| SUCO | SUN domain containing ossification factor | 0.0273954 |
| RO60 | Ro60, Y RNA binding protein | 0.0273725 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.16681 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.122092 |
| PODXL | podocalyxin-like | -0.117405 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0910599 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0868502 |
| HLA-B | major histocompatibility complex, class I, B | -0.0830864 |
| LOX | lysyl oxidase | -0.0756523 |
| NAV1 | neuron navigator 1 | -0.0735859 |
| NDRG1 | N-myc downstream regulated 1 | -0.0717501 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0602552 |
| GLIS3 | GLIS family zinc finger 3 | -0.0547253 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0529379 |
| RIGI | RNA sensor RIG-I | -0.0518102 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0514273 |
| COL5A1 | collagen, type V, alpha 1 | -0.0510181 |
| CD44 | CD44 molecule (Indian blood group) | -0.0498324 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0486297 |
| LOC112694756 | uncharaterized LOC112694756 | -0.046414 |
| THBS2 | thrombospondin 2 | -0.0448781 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0433252 |
| S100A10 | S100 calcium binding protein A10 | -0.0431704 |
| HLA-C | major histocompatibility complex, class I, C | -0.0428603 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0419828 |
| FLNA | filamin A, alpha | -0.0397234 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0390277 |
| VEGFC | vascular endothelial growth factor C | -0.0378893 |
| RNF213 | ring finger protein 213 | -0.0359828 |
| MX2 | MX dynamin-like GTPase 2 | -0.0356713 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0351653 |
| MEIS2 | Meis homeobox 2 | -0.0330563 |
| LMNA | lamin A/C | -0.0328943 |
| RRBP1 | ribosome binding protein 1 | -0.0317596 |
| SP100 | SP100 nuclear antigen | -0.0314235 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0313486 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0310479 |
| EHBP1 | EH domain binding protein 1 | -0.0303588 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0295317 |
| S100A6 | S100 calcium binding protein A6 | -0.0294499 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0286552 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0285328 |
| OSMR | oncostatin M receptor | -0.0283296 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0282222 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.027695 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0265951 |
| PRSS23 | protease, serine, 23 | -0.0255811 |
| ANKRD11 | ankyrin repeat domain 11 | -0.02537 |
| RPL28 | ribosomal protein L28 | -0.0250054 |
| ARF1 | ADP-ribosylation factor 1 | -0.0245616 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0245245 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0235611 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0231536 |
| MAP1B | microtubule-associated protein 1B | -0.0230769 |
| TRIM56 | tripartite motif containing 56 | -0.0228876 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0226973 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0226602 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0222025 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0221823 |
| CAVIN1 | caveolae associated protein 1 | -0.0219319 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0216545 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | -0.0216315 |
| CEP112 | centrosomal protein 112kDa | -0.021616 |
| NR2C2 | nuclear receptor subfamily 2, group C, member 2 | -0.0213843 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0211179 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0211126 |
| EXOC6B | exocyst complex component 6B | -0.0210358 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0207541 |
| PXDN | peroxidasin | -0.0206486 |
| RPL35A | ribosomal protein L35a | -0.0205236 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0201058 |
| RPS19 | ribosomal protein S19 | -0.0201018 |
| YEATS2 | YEATS domain containing 2 | -0.0200643 |
| GSE1 | Gse1 coiled-coil protein | -0.0200005 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0198552 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0198158 |
| S100A4 | S100 calcium binding protein A4 | -0.0195117 |
| GUK1 | guanylate kinase 1 | -0.0194427 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0193949 |
| PMP22 | peripheral myelin protein 22 | -0.0193946 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0192908 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0190119 |
| AGRN | agrin | -0.018927 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0188748 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0186143 |
| IFI44 | interferon-induced protein 44 | -0.0185099 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0184613 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0183852 |
| RPS15 | ribosomal protein S15 | -0.0183454 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0179976 |
| IFI44L | interferon-induced protein 44-like | -0.0177529 |
| PLSCR1 | phospholipid scramblase 1 | -0.017663 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | -0.0176249 |
| TRABD2B | TraB domain containing 2B | -0.0175848 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0174737 |
| NID1 | nidogen 1 | -0.0173592 |
| TNS3 | tensin 3 | -0.0173301 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0173001 |
| SVIL | supervillin | -0.0172765 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0169236 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0167768 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0167492 |
