| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenylephrine (hydrochloride)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.252497 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0967091 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0749586 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0747382 |
| GOLGA4 | golgin A4 | 0.0692644 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.061217 |
| STC1 | stanniocalcin 1 | 0.0605879 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0527409 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0523154 |
| AXL | AXL receptor tyrosine kinase | 0.0516553 |
| VMP1 | vacuole membrane protein 1 | 0.0509194 |
| MT1X | metallothionein 1X | 0.0492226 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0489414 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0488483 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0455012 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0406959 |
| ITSN2 | intersectin 2 | 0.0395924 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0391449 |
| SRP54 | signal recognition particle 54kDa | 0.0391378 |
| SPAG9 | sperm associated antigen 9 | 0.0379299 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0377535 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0375725 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0374232 |
| PGK1 | phosphoglycerate kinase 1 | 0.0373594 |
| USP47 | ubiquitin specific peptidase 47 | 0.0366094 |
| DENND4A | DENN/MADD domain containing 4A | 0.0361238 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0357475 |
| USP34 | ubiquitin specific peptidase 34 | 0.0356586 |
| COPA | coatomer protein complex, subunit alpha | 0.0353607 |
| HIP1 | huntingtin interacting protein 1 | 0.0346144 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0343596 |
| POTEF | POTE ankyrin domain family, member F | 0.0330768 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0329907 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0328499 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0328372 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.032493 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0323875 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.03223 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0320349 |
| VIM | vimentin | 0.031677 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0314657 |
| SEC24A | SEC24 family member A | 0.0313798 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0310646 |
| KRT81 | keratin 81, type II | 0.0304729 |
| FLNB | filamin B, beta | 0.0295835 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0295589 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0292351 |
| NDRG1 | N-myc downstream regulated 1 | 0.0290429 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0286787 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0285139 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0284085 |
| WASF2 | WAS protein family, member 2 | 0.0283015 |
| MCL1 | myeloid cell leukemia 1 | 0.02812 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0281009 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0276107 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0274267 |
| MSN | moesin | 0.0273798 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0273654 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0271062 |
| NGLY1 | N-glycanase 1 | 0.0269705 |
| B2M | beta-2-microglobulin | 0.0269442 |
| GOSR1 | golgi SNAP receptor complex member 1 | 0.0267288 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0265279 |
| TPM4 | tropomyosin 4 | 0.0261486 |
| RND3 | Rho family GTPase 3 | 0.0257319 |
| DSTN | destrin (actin depolymerizing factor) | 0.0256898 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0254226 |
| NUP58 | nucleoporin 58 | 0.0252994 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0252027 |
| TPR | translocated promoter region, nuclear basket protein | 0.0250703 |
| SFTPA2 | surfactant protein A2 | 0.0248376 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0247116 |
| SET | SET nuclear proto-oncogene | 0.0247033 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0245902 |
| TAOK1 | TAO kinase 1 | 0.0242222 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0241332 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0239878 |
| FA2H | fatty acid 2-hydroxylase | 0.0238026 |
| SUCO | SUN domain containing ossification factor | 0.0234899 |
| PAPOLA | poly(A) polymerase alpha | 0.0233827 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0228557 |
| ANXA5 | annexin A5 | 0.0227519 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0224092 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.022349 |
| ADM | adrenomedullin | 0.0221756 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0219427 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0218712 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0217589 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0216206 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0215918 |
| LTBP4 | latent transforming growth factor beta binding protein 4 | 0.0213902 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0211674 |
| TPM3 | tropomyosin 3 | 0.0209354 |
| UBC | ubiquitin C | 0.0208578 |
| CDCA2 | cell division cycle associated 2 | 0.0207488 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0205995 |
| PFKP | phosphofructokinase, platelet | 0.020559 |
| TNS1 | tensin 1 | 0.0204293 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0204117 |
| SBF2 | SET binding factor 2 | 0.020385 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.114974 |
| PDE10A | phosphodiesterase 10A | -0.0930516 |
| KYNU | kynureninase | -0.0921215 |
| TMSB10 | thymosin beta 10 | -0.0868575 |
| RNF213 | ring finger protein 213 | -0.0825947 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0772163 |
| IGF1R | insulin-like growth factor 1 receptor | -0.074857 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0549083 |
| GLIS3 | GLIS family zinc finger 3 | -0.0544186 |
| ACTG1 | actin gamma 1 | -0.054246 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0533416 |
| CMIP | c-Maf inducing protein | -0.0517568 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0511275 |
| NCOA7 | nuclear receptor coactivator 7 | -0.050171 |
| RPLP1 | ribosomal protein, large, P1 | -0.0493276 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0449651 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0449167 |
| OSMR | oncostatin M receptor | -0.0444256 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0426578 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0411263 |
| RRBP1 | ribosome binding protein 1 | -0.0406627 |
| TNS3 | tensin 3 | -0.0402131 |
| EHBP1 | EH domain binding protein 1 | -0.0396508 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0395522 |
| AUTS2 | autism susceptibility candidate 2 | -0.039355 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0389668 |
| NRP1 | neuropilin 1 | -0.0387567 |
| RPL23 | ribosomal protein L23 | -0.0373673 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0371585 |
| RPL13A | ribosomal protein L13a | -0.036396 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0360238 |
| RPS24 | ribosomal protein S24 | -0.0356604 |
| BICC1 | BicC family RNA binding protein 1 | -0.0345057 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0342086 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0342053 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0341438 |
| PLEC | plectin | -0.0333182 |
| DOCK4 | dedicator of cytokinesis 4 | -0.031992 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0317619 |
| TXNRD1 | thioredoxin reductase 1 | -0.0317441 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0313265 |
| AOPEP | aminopeptidase O (putative) | -0.0296152 |
| EGFR | epidermal growth factor receptor | -0.0292911 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0284115 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0281924 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0274669 |
| WWOX | WW domain containing oxidoreductase | -0.0272944 |
| ETV6 | ets variant 6 | -0.0272211 |
| ASPH | aspartate beta-hydroxylase | -0.0268477 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0266313 |
| RPL38 | ribosomal protein L38 | -0.0258787 |
| RPS16 | ribosomal protein S16 | -0.0256296 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0255625 |
| FLNA | filamin A, alpha | -0.0253552 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0252078 |
| RPL28 | ribosomal protein L28 | -0.0247425 |
| LAMA5 | laminin, alpha 5 | -0.0245852 |
| TGM2 | transglutaminase 2 | -0.0245363 |
| GABRB3 | gamma-aminobutyric acid (GABA) A receptor, beta 3 | -0.024444 |
| EFNA5 | ephrin-A5 | -0.023792 |
| KIAA1217 | KIAA1217 | -0.0236732 |
| EXOC6B | exocyst complex component 6B | -0.0232646 |
| PLSCR1 | phospholipid scramblase 1 | -0.0232268 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0229104 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0229025 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0226423 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0223324 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0223303 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0222335 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0220741 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0215267 |
| EVA1C | eva-1 homolog C (C. elegans) | -0.021412 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0212995 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.021196 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0208647 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0208057 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0204616 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0204183 |
| RPL26 | ribosomal protein L26 | -0.0202387 |
| GRAMD1B | GRAM domain containing 1B | -0.0201016 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0199728 |
| CUX1 | cut-like homeobox 1 | -0.0199286 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0196132 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0195964 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0195959 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0193212 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0191374 |
| RSPO3 | R-spondin 3 | -0.0191146 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0187533 |
| MSI2 | musashi RNA-binding protein 2 | -0.0185437 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.018326 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0181715 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0180345 |
| MYO10 | myosin X | -0.0180326 |
| LMNA | lamin A/C | -0.0175589 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0174702 |
| ANKRD28 | ankyrin repeat domain 28 | -0.017326 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0172676 |
| BMERB1 | bMERB domain containing 1 | -0.0172265 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0171477 |
