| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenylephrine (hydrochloride)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.105076 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0768693 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0759207 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0756172 |
| PHF3 | PHD finger protein 3 | 0.0723014 |
| ZNF292 | zinc finger protein 292 | 0.0714875 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0691377 |
| OGA | O-GlcNAcase | 0.0689422 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0670244 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0658457 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0651756 |
| RPS2 | ribosomal protein S2 | 0.0617318 |
| PEG10 | paternally expressed 10 | 0.0597643 |
| CENPF | centromere protein F, 350/400kDa | 0.0585377 |
| QKI | QKI, KH domain containing, RNA binding | 0.0528017 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0509666 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.0496426 |
| PRELID2 | PRELI domain containing 2 | 0.0480779 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0476911 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.047225 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0467375 |
| TUT4 | terminal uridylyl transferase 4 | 0.0465071 |
| CANX | calnexin | 0.0461866 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0457094 |
| ANLN | anillin, actin binding protein | 0.0448848 |
| GSE1 | Gse1 coiled-coil protein | 0.0437932 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.043783 |
| WDR45B | WD repeat domain 45B | 0.0435317 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0428741 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0415856 |
| XPO1 | exportin 1 | 0.0414335 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.040888 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0394997 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0391648 |
| HELZ | helicase with zinc finger | 0.0385214 |
| PGK1 | phosphoglycerate kinase 1 | 0.0376146 |
| TPX2 | TPX2, microtubule-associated | 0.0374429 |
| KIF11 | kinesin family member 11 | 0.0369829 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0365094 |
| ITGAV | integrin, alpha V | 0.0353864 |
| NKTR | natural killer cell triggering receptor | 0.0349688 |
| YME1L1 | YME1-like 1 ATPase | 0.0348966 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0348691 |
| RNF145 | ring finger protein 145 | 0.034687 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0342643 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0337926 |
| B2M | beta-2-microglobulin | 0.0336662 |
| ZNF654 | zinc finger protein 654 | 0.0332707 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0331952 |
| TMSB4X | thymosin beta 4, X-linked | 0.0328539 |
| CDK19 | cyclin-dependent kinase 19 | 0.0327437 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0327411 |
| HMGB2 | high mobility group box 2 | 0.0323101 |
| KLHDC10 | kelch domain containing 10 | 0.0321726 |
| SETD5 | SET domain containing 5 | 0.0318251 |
| ITM2B | integral membrane protein 2B | 0.0316193 |
| LNPK | lunapark, ER junction formation factor | 0.0316006 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0310885 |
| TNPO1 | transportin 1 | 0.0309228 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0300686 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.0298491 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.029835 |
| FOXC1 | forkhead box C1 | 0.0297545 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0297143 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.02964 |
| IL6ST | interleukin 6 signal transducer | 0.0295847 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0294232 |
| FAM13A | family with sequence similarity 13, member A | 0.0292839 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0292792 |
| HYOU1 | hypoxia up-regulated 1 | 0.0291699 |
| NUP58 | nucleoporin 58 | 0.028733 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0286184 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0285406 |
| CCSER2 | coiled-coil serine-rich protein 2 | 0.0285097 |
| CEP295 | centrosomal protein 295kDa | 0.0283822 |
| CEP350 | centrosomal protein 350kDa | 0.0283207 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0282222 |
| MTF2 | metal response element binding transcription factor 2 | 0.0280906 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0280886 |
| DEK | DEK proto-oncogene | 0.0277772 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | 0.0276966 |
| MEOX2 | mesenchyme homeobox 2 | 0.0275856 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0275835 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0275323 |
| ZNF608 | zinc finger protein 608 | 0.0274058 |
| WDR43 | WD repeat domain 43 | 0.0271997 |
| CCNB1 | cyclin B1 | 0.0271993 |
| MEF2A | myocyte enhancer factor 2A | 0.0271341 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0270352 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.026836 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | 0.0268103 |
| ITGA6 | integrin, alpha 6 | 0.0265822 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0262331 |
| PTMA | prothymosin, alpha | 0.0260214 |
| RBM33 | RNA binding motif protein 33 | 0.0260046 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0259507 |
| CDC27 | cell division cycle 27 | 0.0257923 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0257666 |
| IPMK | inositol polyphosphate multikinase | 0.0257285 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0256452 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM2 | cell adhesion molecule 2 | -0.143152 |
| MEST | mesoderm specific transcript | -0.141159 |
| HMGA2 | high mobility group AT-hook 2 | -0.13073 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.107559 |
| VIM | vimentin | -0.106419 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0718243 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0659282 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0626841 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0613393 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0601583 |
| CTBP2 | C-terminal binding protein 2 | -0.0595713 |
| VEGFA | vascular endothelial growth factor A | -0.059064 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0560516 |
| MAP1B | microtubule-associated protein 1B | -0.053744 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.051398 |
| HMGA1 | high mobility group AT-hook 1 | -0.0499047 |
| TMSB10 | thymosin beta 10 | -0.0494019 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0480325 |
| RPS24 | ribosomal protein S24 | -0.0477218 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.047576 |
| KAZN | kazrin, periplakin interacting protein | -0.0466579 |
| ACTG1 | actin gamma 1 | -0.044396 |
| RPL31 | ribosomal protein L31 | -0.0431393 |
| MGP | matrix Gla protein | -0.0430332 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0418599 |
| EGFR | epidermal growth factor receptor | -0.04082 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0400902 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0395523 |
| RPS14 | ribosomal protein S14 | -0.0384691 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0384151 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0383629 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0367633 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.036658 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0357494 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0348843 |
| RPL34 | ribosomal protein L34 | -0.0345343 |
| RPS16 | ribosomal protein S16 | -0.0340705 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0340286 |
| AK1 | adenylate kinase 1 | -0.0334252 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0331928 |
| ZFHX3 | zinc finger homeobox 3 | -0.0329583 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0329029 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.032881 |
| JMJD1C | jumonji domain containing 1C | -0.0323565 |
| RANBP17 | RAN binding protein 17 | -0.0322666 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0317948 |
| SIK3 | SIK family kinase 3 | -0.0316785 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0316224 |
| RSU1 | Ras suppressor protein 1 | -0.0310715 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0310712 |
| MEIS2 | Meis homeobox 2 | -0.0309921 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0308796 |
| CUX1 | cut-like homeobox 1 | -0.0303176 |
| RPLP1 | ribosomal protein, large, P1 | -0.0301036 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0296136 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0294078 |
| RPL28 | ribosomal protein L28 | -0.0292578 |
| POTEF | POTE ankyrin domain family, member F | -0.0292023 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | -0.0290044 |
| S100A9 | S100 calcium binding protein A9 | -0.0289886 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0289579 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0289142 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0286364 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0285516 |
| RPS17 | ribosomal protein S17 | -0.0284947 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0284678 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0284249 |
| TFCP2 | transcription factor CP2 | -0.0283585 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0283071 |
| FLNA | filamin A, alpha | -0.0280633 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0278763 |
| PKM | pyruvate kinase, muscle | -0.027762 |
| RPL7A | ribosomal protein L7a | -0.0276568 |
| RPL23 | ribosomal protein L23 | -0.0276271 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0276001 |
| MSI2 | musashi RNA-binding protein 2 | -0.027577 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0275161 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0274354 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0274117 |
| BRD4 | bromodomain containing 4 | -0.0273027 |
| RPL35 | ribosomal protein L35 | -0.0271774 |
| ZNF609 | zinc finger protein 609 | -0.0270338 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0270104 |
| FOXO3 | forkhead box O3 | -0.0263828 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0262197 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.02599 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0257449 |
| RPS23 | ribosomal protein S23 | -0.0257216 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.0255715 |
| RPS13 | ribosomal protein S13 | -0.0255612 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.0255237 |
| AFAP1 | actin filament associated protein 1 | -0.0253246 |
| RPS29 | ribosomal protein S29 | -0.0252737 |
| EFNA5 | ephrin-A5 | -0.0251758 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0251696 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0245573 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.0244948 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0244338 |
| BSG | basigin (Ok blood group) | -0.0243353 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0243154 |
