| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenylephrine (hydrochloride)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.121265 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.097371 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0750118 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0724785 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0720889 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0666361 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0632833 |
| EZR | ezrin | 0.0598745 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0594037 |
| RBM39 | RNA binding motif protein 39 | 0.0583961 |
| PTK2 | protein tyrosine kinase 2 | 0.0570905 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0559347 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0535326 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0531559 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0517827 |
| SPAG9 | sperm associated antigen 9 | 0.0493352 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0488428 |
| PTMA | prothymosin, alpha | 0.0486509 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0479301 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.047693 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0467662 |
| EPCAM | epithelial cell adhesion molecule | 0.0463995 |
| NCKAP1 | NCK-associated protein 1 | 0.0458296 |
| RIOK3 | RIO kinase 3 | 0.0457115 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0434612 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0430661 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0430047 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0429447 |
| KIF5B | kinesin family member 5B | 0.0413339 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0412384 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0406658 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0406024 |
| MYO6 | myosin VI | 0.0405223 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0403426 |
| MATR3 | matrin 3 | 0.0401554 |
| VMP1 | vacuole membrane protein 1 | 0.0399449 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0385884 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0384622 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0381016 |
| DSPP | dentin sialophosphoprotein | 0.0376563 |
| B2M | beta-2-microglobulin | 0.0372687 |
| CORO1C | coronin, actin binding protein, 1C | 0.0367542 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0364347 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0353043 |
| SMAD3 | SMAD family member 3 | 0.0345539 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.0340298 |
| TOP1 | topoisomerase (DNA) I | 0.0336466 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0329249 |
| CANX | calnexin | 0.0325249 |
| AFDN | afadin, adherens junction formation factor | 0.0318534 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0317014 |
| SQSTM1 | sequestosome 1 | 0.0315615 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0312067 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0311928 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0309344 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0308822 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0307556 |
| TMEM41B | transmembrane protein 41B | 0.0305983 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0304102 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.029973 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0293771 |
| ABI1 | abl-interactor 1 | 0.0292746 |
| NEK7 | NIMA-related kinase 7 | 0.0288676 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0287027 |
| ACTG1 | actin gamma 1 | 0.0286466 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0286451 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0284085 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0283722 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0279281 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0278222 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0277203 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0272746 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0270823 |
| VCL | vinculin | 0.0269648 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.026793 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0266641 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0263408 |
| WASF2 | WAS protein family, member 2 | 0.0261956 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0261338 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0261078 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0260681 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0257499 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0255298 |
| YME1L1 | YME1-like 1 ATPase | 0.0254136 |
| CUL3 | cullin 3 | 0.025365 |
| FOXO3 | forkhead box O3 | 0.0253513 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0250487 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0250369 |
| CHKA | choline kinase alpha | 0.024948 |
| PAPOLA | poly(A) polymerase alpha | 0.0248417 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0248018 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0247976 |
| CD164 | CD164 molecule, sialomucin | 0.0246414 |
| RANBP2 | RAN binding protein 2 | 0.0242228 |
| RPL4 | ribosomal protein L4 | 0.0242165 |
| USP12 | ubiquitin specific peptidase 12 | 0.0241375 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0240219 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0238 |
| SERINC1 | serine incorporator 1 | 0.0236971 |
| CCNT2 | cyclin T2 | 0.0235054 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.213834 |
| TMSB10 | thymosin beta 10 | -0.147355 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.139019 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.116117 |
| FLNB | filamin B, beta | -0.105926 |
| POTEF | POTE ankyrin domain family, member F | -0.0969246 |
| TXNIP | thioredoxin interacting protein | -0.0895951 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0845381 |
| MUC17 | mucin 17, cell surface associated | -0.0810138 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0768149 |
| HMGA2 | high mobility group AT-hook 2 | -0.075207 |
| EGFR | epidermal growth factor receptor | -0.0751672 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0732448 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.068947 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0657519 |
| S100A10 | S100 calcium binding protein A10 | -0.0641763 |
| VIM | vimentin | -0.0641413 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0626369 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0623514 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0619499 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0596551 |
| HMGA1 | high mobility group AT-hook 1 | -0.0582193 |
| LDHA | lactate dehydrogenase A | -0.0574388 |
| LAMB3 | laminin, beta 3 | -0.0561982 |
| KLK10 | kallikrein-related peptidase 10 | -0.0550047 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0534312 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.050224 |
| ANXA2 | annexin A2 | -0.0450865 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0439327 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0423173 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0417972 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0417478 |
| EGR1 | early growth response 1 | -0.0412515 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0409687 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0402583 |
| S100A11 | S100 calcium binding protein A11 | -0.039924 |
| MT2A | metallothionein 2A | -0.0396711 |
| NPSR1 | neuropeptide S receptor 1 | -0.0391732 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0387964 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0383816 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0368861 |
| CLMP | CXADR-like membrane protein | -0.0367091 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0357732 |
| SBF2 | SET binding factor 2 | -0.0354421 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0347697 |
| FTL | ferritin, light polypeptide | -0.0346246 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0344844 |
| SP100 | SP100 nuclear antigen | -0.0342159 |
| FAM13A | family with sequence similarity 13, member A | -0.0339226 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.033821 |
| RPL37A | ribosomal protein L37a | -0.0332045 |
| MXD1 | MAX dimerization protein 1 | -0.0329901 |
| UBC | ubiquitin C | -0.0324822 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.032314 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0323039 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0321355 |
| TGM2 | transglutaminase 2 | -0.031639 |
| MCL1 | myeloid cell leukemia 1 | -0.0314169 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0312042 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0311866 |
| ANXA1 | annexin A1 | -0.0309599 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.03069 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0302897 |
| RPL35A | ribosomal protein L35a | -0.0302825 |
| CCDC88A | coiled-coil domain containing 88A | -0.0302061 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0293591 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0292434 |
| DIAPH2 | diaphanous-related formin 2 | -0.0290692 |
| FERMT1 | fermitin family member 1 | -0.029052 |
| RAB7A | RAB7A, member RAS oncogene family | -0.028636 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0285777 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0285159 |
| RPL12 | ribosomal protein L12 | -0.0283569 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0277686 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0277278 |
| CSTB | cystatin B (stefin B) | -0.0276591 |
| ITGB4 | integrin, beta 4 | -0.0275033 |
| FAM107B | family with sequence similarity 107, member B | -0.0274935 |
| RNF213 | ring finger protein 213 | -0.0273601 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.027158 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0271402 |
| S100A6 | S100 calcium binding protein A6 | -0.0271188 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.027062 |
| SEC24A | SEC24 family member A | -0.0269069 |
| FKBP5 | FK506 binding protein 5 | -0.0267824 |
| VDAC1 | voltage-dependent anion channel 1 | -0.026638 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0264854 |
| RRBP1 | ribosome binding protein 1 | -0.0264051 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0263186 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0255616 |
| KLF6 | Kruppel-like factor 6 | -0.0254341 |
| SREK1IP1 | SREK1-interacting protein 1 | -0.0246047 |
| FMNL2 | formin-like 2 | -0.0243609 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0238545 |
| FAM3C | family with sequence similarity 3, member C | -0.0236448 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0235252 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0232334 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0230585 |
| JUP | junction plakoglobin | -0.0229896 |
| DUSP6 | dual specificity phosphatase 6 | -0.0227815 |
