| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenylephrine (hydrochloride)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.134943 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.114621 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.100585 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0862279 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0837469 |
| TMSB4X | thymosin beta 4, X-linked | 0.083223 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0760345 |
| SPAG9 | sperm associated antigen 9 | 0.0729622 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0718963 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0712698 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0710263 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0706872 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0671716 |
| RBM39 | RNA binding motif protein 39 | 0.0635162 |
| FAM13A | family with sequence similarity 13, member A | 0.0565678 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0547354 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0520362 |
| CCNL1 | cyclin L1 | 0.0513457 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0501922 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0500985 |
| PGK1 | phosphoglycerate kinase 1 | 0.0489341 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0484724 |
| DENND4A | DENN/MADD domain containing 4A | 0.0484436 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.047705 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0433846 |
| VMP1 | vacuole membrane protein 1 | 0.0432432 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0430283 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0429894 |
| B2M | beta-2-microglobulin | 0.0413782 |
| APP | amyloid beta (A4) precursor protein | 0.0413529 |
| RPL4 | ribosomal protein L4 | 0.040662 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.04065 |
| PLAU | plasminogen activator, urokinase | 0.0403513 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0400198 |
| ENO1 | enolase 1, (alpha) | 0.039598 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0391625 |
| INSIG2 | insulin induced gene 2 | 0.038102 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0379384 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0376098 |
| PAPOLA | poly(A) polymerase alpha | 0.0375196 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0373941 |
| EREG | epiregulin | 0.0373182 |
| CANX | calnexin | 0.0369053 |
| TXNRD1 | thioredoxin reductase 1 | 0.0356596 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0348647 |
| NUP58 | nucleoporin 58 | 0.0347121 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0346412 |
| KIF5B | kinesin family member 5B | 0.0344465 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0343505 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0342956 |
| ASPH | aspartate beta-hydroxylase | 0.0342016 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0335739 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0334818 |
| HELZ | helicase with zinc finger | 0.0330743 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.032942 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0326735 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0325984 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.032535 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0323456 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0320538 |
| TPM1 | tropomyosin 1 (alpha) | 0.0319893 |
| HMGB2 | high mobility group box 2 | 0.0317106 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0315886 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.031541 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0314529 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0312809 |
| SMAD3 | SMAD family member 3 | 0.0307515 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0306124 |
| EZR | ezrin | 0.0301386 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0294235 |
| RPL5 | ribosomal protein L5 | 0.0293649 |
| FOXO3 | forkhead box O3 | 0.029144 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0288332 |
| MT2A | metallothionein 2A | 0.0286988 |
| TFRC | transferrin receptor | 0.0285502 |
| MICU1 | mitochondrial calcium uptake 1 | 0.0284659 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0284476 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0283496 |
| RPS3 | ribosomal protein S3 | 0.0283298 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0281767 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.028074 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0278776 |
| HSPA8 | heat shock 70kDa protein 8 | 0.027409 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0273245 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0270474 |
| NCKAP1 | NCK-associated protein 1 | 0.0269484 |
| TPM3 | tropomyosin 3 | 0.0269192 |
| UBC | ubiquitin C | 0.0268777 |
| MYOF | myoferlin | 0.0266708 |
| RPLP0 | ribosomal protein, large, P0 | 0.0263839 |
| FAM3C | family with sequence similarity 3, member C | 0.0263432 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.026166 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0261566 |
| ARRDC3 | arrestin domain containing 3 | 0.0260755 |
| CCNY | cyclin Y | 0.0259298 |
| PNN | pinin, desmosome associated protein | 0.025921 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0256385 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0256274 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.025535 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0254289 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.163495 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.117977 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.117955 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.101404 |
| TMSB10 | thymosin beta 10 | -0.0981267 |
| MMP7 | matrix metallopeptidase 7 | -0.0968145 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.069416 |
| RNF213 | ring finger protein 213 | -0.0628192 |
| KRT19 | keratin 19, type I | -0.0616275 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0613824 |
| MX1 | MX dynamin-like GTPase 1 | -0.0555292 |
| EFNA5 | ephrin-A5 | -0.0522986 |
| VIM | vimentin | -0.0511614 |
| HLA-B | major histocompatibility complex, class I, B | -0.0509367 |
| JUP | junction plakoglobin | -0.0501791 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0499339 |
| NRG3 | neuregulin 3 | -0.04946 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0481096 |
| MUC4 | mucin 4, cell surface associated | -0.0475158 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0471169 |
| LOC112694756 | uncharaterized LOC112694756 | -0.045873 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0448608 |
| FTL | ferritin, light polypeptide | -0.0440745 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0439411 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0422194 |
| RAD51B | RAD51 paralog B | -0.0418416 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0413324 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0411557 |
| LAMB3 | laminin, beta 3 | -0.0404847 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.039558 |
| MX2 | MX dynamin-like GTPase 2 | -0.0386875 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.038151 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0380122 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0375097 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0368398 |
| HMGA1 | high mobility group AT-hook 1 | -0.0362847 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.036267 |
| LMO7 | LIM domain 7 | -0.0359213 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0346757 |
| MAP1B | microtubule-associated protein 1B | -0.0342312 |
| OSMR | oncostatin M receptor | -0.0339975 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0324984 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0322854 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0317591 |
| PCDH7 | protocadherin 7 | -0.0313079 |
| OPTN | optineurin | -0.0296764 |
| S100A10 | S100 calcium binding protein A10 | -0.029441 |
| RRBP1 | ribosome binding protein 1 | -0.0291573 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0287957 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0285909 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.028282 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0279852 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0274332 |
| HLA-A | major histocompatibility complex, class I, A | -0.0268008 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0267033 |
| TMC5 | transmembrane channel-like 5 | -0.0265362 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0263373 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0260163 |
| ITGB4 | integrin, beta 4 | -0.0252389 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0251549 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0250201 |
| CP | ceruloplasmin (ferroxidase) | -0.0249598 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0249402 |
| LAMC2 | laminin, gamma 2 | -0.0244356 |
| NCKAP5 | NCK-associated protein 5 | -0.0244281 |
| NRP1 | neuropilin 1 | -0.0243949 |
| H1-0 | H1.0 linker histone | -0.0243704 |
| EGFR | epidermal growth factor receptor | -0.0243141 |
| RPLP1 | ribosomal protein, large, P1 | -0.024274 |
| DST | dystonin | -0.0240195 |
| LAMA5 | laminin, alpha 5 | -0.0238787 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0238478 |
| BCL2L1 | BCL2-like 1 | -0.0237353 |
| MYO1E | myosin IE | -0.0237067 |
| MUC1 | mucin 1, cell surface associated | -0.0234188 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0233713 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0231876 |
| HMGA2 | high mobility group AT-hook 2 | -0.0231356 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0228921 |
| AHR | aryl hydrocarbon receptor | -0.0227132 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0226113 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0225923 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0222729 |
| ZNF609 | zinc finger protein 609 | -0.0222167 |
| ITGA1 | integrin, alpha 1 | -0.0220116 |
| LAMA4 | laminin, alpha 4 | -0.0219709 |
| S100A11 | S100 calcium binding protein A11 | -0.0219549 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0219098 |
| NDRG1 | N-myc downstream regulated 1 | -0.021892 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.021845 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0217667 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0215644 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.0209073 |
| SP100 | SP100 nuclear antigen | -0.0208269 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0207783 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.020764 |
| SVIL | supervillin | -0.0207573 |
| MUC16 | mucin 16, cell surface associated | -0.0205323 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0205076 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0202277 |
