| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Phenylephrine (hydrochloride)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.452438 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.115446 |
| LPIN1 | lipin 1 | 0.106088 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0656142 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0642134 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.063219 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0554122 |
| DPH6 | diphthamine biosynthesis 6 | 0.0536617 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0534878 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0522238 |
| QKI | QKI, KH domain containing, RNA binding | 0.0453661 |
| CLTC | clathrin, heavy chain (Hc) | 0.0438682 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0412042 |
| HELZ | helicase with zinc finger | 0.0392998 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0387398 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0379367 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0371661 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0366991 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0362937 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.035966 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0346523 |
| MATR3 | matrin 3 | 0.0335083 |
| PAPOLA | poly(A) polymerase alpha | 0.0334641 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0332522 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0325046 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0322492 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0319674 |
| PTEN | phosphatase and tensin homolog | 0.0318732 |
| RNF145 | ring finger protein 145 | 0.0308135 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0307548 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0307074 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0306663 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0306177 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0305849 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0304233 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0304143 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0303865 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0301737 |
| PKM | pyruvate kinase, muscle | 0.0299508 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0299343 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0291797 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0290517 |
| SUCO | SUN domain containing ossification factor | 0.0286061 |
| PTMA | prothymosin, alpha | 0.0282926 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0282714 |
| ANGPT1 | angiopoietin 1 | 0.0281626 |
| SRP72 | signal recognition particle 72kDa | 0.0281027 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0272766 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0272103 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.026901 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0267618 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0267499 |
| WAC | WW domain containing adaptor with coiled-coil | 0.026558 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0260785 |
| PCDH9 | protocadherin 9 | 0.0260137 |
| VMP1 | vacuole membrane protein 1 | 0.0260135 |
| ENAH | enabled homolog (Drosophila) | 0.0259195 |
| RPL37A | ribosomal protein L37a | 0.0257635 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0255825 |
| CEP95 | centrosomal protein 95kDa | 0.0255757 |
| SET | SET nuclear proto-oncogene | 0.0255506 |
| WDR43 | WD repeat domain 43 | 0.0254376 |
| ARRDC3 | arrestin domain containing 3 | 0.0253141 |
| SRPK2 | SRSF protein kinase 2 | 0.0253104 |
| INSIG2 | insulin induced gene 2 | 0.0251175 |
| SMYD3 | SET and MYND domain containing 3 | 0.0248361 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0247828 |
| DTNA | dystrobrevin, alpha | 0.0246877 |
| PCBP2 | poly(rC) binding protein 2 | 0.0246337 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0245736 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0243817 |
| TXNRD1 | thioredoxin reductase 1 | 0.024174 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0241057 |
| RPL5 | ribosomal protein L5 | 0.0240252 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0240014 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0237957 |
| RIOK3 | RIO kinase 3 | 0.0236714 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 0.0235046 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0234957 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0233246 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0233215 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0232319 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0229723 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0229047 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0227187 |
| PTCD3 | pentatricopeptide repeat domain 3 | 0.02268 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0226701 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0226248 |
| RFX7 | regulatory factor X, 7 | 0.0225171 |
| TFG | TRK-fused gene | 0.0224785 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0224774 |
| COPS2 | COP9 signalosome subunit 2 | 0.0224722 |
| PTK2 | protein tyrosine kinase 2 | 0.0224697 |
| CCNL1 | cyclin L1 | 0.0223569 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0220057 |
| TCERG1 | transcription elongation regulator 1 | 0.0216129 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0215319 |
| B2M | beta-2-microglobulin | 0.0213023 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0212971 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | 0.0211269 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.29046 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0792159 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.070632 |
| NRG1 | neuregulin 1 | -0.0659579 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0608994 |
| RIGI | RNA sensor RIG-I | -0.0603671 |
| SYT1 | synaptotagmin I | -0.0560065 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0496782 |
| VCL | vinculin | -0.0480962 |
| RNF213 | ring finger protein 213 | -0.0479403 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0465718 |
| FAM107B | family with sequence similarity 107, member B | -0.0460846 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0454517 |
| PLPP1 | phospholipid phosphatase 1 | -0.0411863 |
| GLCCI1 | glucocorticoid induced 1 | -0.0402504 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.039719 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.039103 |
| SP100 | SP100 nuclear antigen | -0.037379 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0364172 |
| COL1A1 | collagen, type I, alpha 1 | -0.0364094 |
| TLE4 | transducin-like enhancer of split 4 | -0.0355145 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0348956 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0347037 |
| ZNF804A | zinc finger protein 804A | -0.0345491 |
| MYO9A | myosin IXA | -0.0344807 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0344684 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0341138 |
| FRMD4A | FERM domain containing 4A | -0.0334373 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0333215 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0332812 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.032792 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0327163 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0320062 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0310144 |
| STK38L | serine/threonine kinase 38 like | -0.03092 |
| PDE10A | phosphodiesterase 10A | -0.0307546 |
| AOPEP | aminopeptidase O (putative) | -0.0306219 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0305657 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.029611 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0294032 |
| EXOC4 | exocyst complex component 4 | -0.0293236 |
| SETBP1 | SET binding protein 1 | -0.0291406 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0289756 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0286782 |
| KLHL13 | kelch-like family member 13 | -0.0282885 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0275559 |
| TPM1 | tropomyosin 1 (alpha) | -0.0274434 |
| ITGAV | integrin, alpha V | -0.0270507 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0269003 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.026447 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0259871 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0259698 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0256472 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0256076 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0242753 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0242219 |
| NDRG1 | N-myc downstream regulated 1 | -0.0237949 |
| CADM1 | cell adhesion molecule 1 | -0.0235502 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0233084 |
| FNBP1 | formin binding protein 1 | -0.0229984 |
| NUMB | numb homolog (Drosophila) | -0.022814 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.022689 |
| THBS1 | thrombospondin 1 | -0.0224757 |
| IRS1 | insulin receptor substrate 1 | -0.022429 |
| AUTS2 | autism susceptibility candidate 2 | -0.0222614 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0222573 |
| FOXP1 | forkhead box P1 | -0.0221333 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0221062 |
| PCBP3 | poly(rC) binding protein 3 | -0.0220489 |
| HIP1 | huntingtin interacting protein 1 | -0.0215803 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0214165 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0213853 |
| FAM13B | family with sequence similarity 13, member B | -0.0213627 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.0212641 |
| CEP170 | centrosomal protein 170kDa | -0.0210648 |
| SIK2 | salt-inducible kinase 2 | -0.020946 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0209193 |
| FRMD5 | FERM domain containing 5 | -0.0207621 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0206454 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0204617 |
| AHI1 | Abelson helper integration site 1 | -0.0203182 |
| PRKCA | protein kinase C, alpha | -0.0203019 |
| CTBP2 | C-terminal binding protein 2 | -0.0202488 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0199342 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0199321 |
| NRP1 | neuropilin 1 | -0.0198523 |
| RUNX1 | runt-related transcription factor 1 | -0.0197513 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0195986 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0194369 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0193746 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0193492 |
| MKI67 | marker of proliferation Ki-67 | -0.0193347 |
| COPA | coatomer protein complex, subunit alpha | -0.0191712 |
| FOXN3 | forkhead box N3 | -0.0190336 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0190183 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0189576 |
| LDHA | lactate dehydrogenase A | -0.0189505 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0188552 |
| PLAT | plasminogen activator, tissue | -0.0187782 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | -0.0187467 |
