| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenylephrine (hydrochloride)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MACC1 | metastasis associated in colon cancer 1 | 0.0836525 |
| B2M | beta-2-microglobulin | 0.0744701 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0699675 |
| TXNIP | thioredoxin interacting protein | 0.0656314 |
| DSCAM | Down syndrome cell adhesion molecule | 0.061157 |
| IFNGR1 | interferon gamma receptor 1 | 0.0575199 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0562455 |
| VMP1 | vacuole membrane protein 1 | 0.0550885 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0500287 |
| MYO1E | myosin IE | 0.0485865 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0479891 |
| STK24 | serine/threonine kinase 24 | 0.0427483 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.042648 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0400889 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0396608 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0381754 |
| CLTC | clathrin, heavy chain (Hc) | 0.0378468 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0362462 |
| ERBIN | erbb2 interacting protein | 0.0343186 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0339626 |
| TMC5 | transmembrane channel-like 5 | 0.0335246 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0335133 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0329259 |
| EPCAM | epithelial cell adhesion molecule | 0.0328808 |
| LIMA1 | LIM domain and actin binding 1 | 0.0321851 |
| EZR | ezrin | 0.0306137 |
| PGK1 | phosphoglycerate kinase 1 | 0.0303391 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0296665 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0296187 |
| KIF13B | kinesin family member 13B | 0.0288116 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.0286104 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0286064 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0277521 |
| SPAG9 | sperm associated antigen 9 | 0.0275363 |
| LMO7 | LIM domain 7 | 0.0272868 |
| MICU2 | mitochondrial calcium uptake 2 | 0.0272132 |
| CDHR2 | cadherin-related family member 2 | 0.0269355 |
| WASF2 | WAS protein family, member 2 | 0.0268108 |
| TAOK3 | TAO kinase 3 | 0.0265994 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0262117 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0257299 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0253839 |
| CD2AP | CD2-associated protein | 0.025361 |
| ITGA6 | integrin, alpha 6 | 0.0248966 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0247709 |
| LYZ | lysozyme | 0.0244969 |
| TSPAN3 | tetraspanin 3 | 0.0244595 |
| PDZD8 | PDZ domain containing 8 | 0.02423 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0240042 |
| RND3 | Rho family GTPase 3 | 0.0238394 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0234187 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0232661 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0229146 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0228374 |
| TFRC | transferrin receptor | 0.0225901 |
| PNPLA7 | patatin-like phospholipase domain containing 7 | 0.0225582 |
| TJP1 | tight junction protein 1 | 0.0225234 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0223877 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0223472 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0223252 |
| RBM47 | RNA binding motif protein 47 | 0.022228 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0217342 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0209736 |
| EFHD2 | EF-hand domain family, member D2 | 0.0209436 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0204927 |
| GOLGB1 | golgin B1 | 0.0204776 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0204072 |
| CANX | calnexin | 0.0202541 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0202176 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0200321 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0200064 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0198492 |
| DSPP | dentin sialophosphoprotein | 0.0196761 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0196091 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0195969 |
| ALPK1 | alpha-kinase 1 | 0.0195886 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0195135 |
| NDFIP2 | Nedd4 family interacting protein 2 | 0.0195021 |
| MAP7 | microtubule-associated protein 7 | 0.0192717 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0188661 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0187744 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0187518 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0187125 |
| EFNB2 | ephrin-B2 | 0.0184071 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0183935 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.018302 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0182766 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0182396 |
| DIAPH1 | diaphanous-related formin 1 | 0.0179255 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0179204 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0178156 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0176858 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0174352 |
| MCU | mitochondrial calcium uniporter | 0.0173299 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0172755 |
| MYO10 | myosin X | 0.0170834 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0170112 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0169857 |
| CEP95 | centrosomal protein 95kDa | 0.0169803 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0169014 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RUNX1 | runt-related transcription factor 1 | -0.0819696 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0790625 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0752716 |
| LCN2 | lipocalin 2 | -0.0714638 |
| HLA-B | major histocompatibility complex, class I, B | -0.0586869 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.055379 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0550559 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0475851 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0456893 |
| TMSB10 | thymosin beta 10 | -0.0456508 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0451302 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0447458 |
| NDRG1 | N-myc downstream regulated 1 | -0.0436665 |
| RNF43 | ring finger protein 43 | -0.0417984 |
| RPLP1 | ribosomal protein, large, P1 | -0.041471 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0374843 |
| FTL | ferritin, light polypeptide | -0.0374714 |
| RPS6 | ribosomal protein S6 | -0.0366716 |
| WWOX | WW domain containing oxidoreductase | -0.036666 |
| RPL35A | ribosomal protein L35a | -0.0364525 |
| HLA-C | major histocompatibility complex, class I, C | -0.0334458 |
| AGR2 | anterior gradient 2 | -0.0327337 |
| PKM | pyruvate kinase, muscle | -0.032649 |
| RPL23 | ribosomal protein L23 | -0.0316742 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0310251 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0305745 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0305707 |
| SQSTM1 | sequestosome 1 | -0.0297091 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0296085 |
| MT2A | metallothionein 2A | -0.028275 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0281193 |
| UBAC2 | UBA domain containing 2 | -0.0278059 |
| RPS24 | ribosomal protein S24 | -0.027611 |
| EPHB2 | EPH receptor B2 | -0.027458 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0269062 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0267629 |
| LOC112694756 | uncharaterized LOC112694756 | -0.026574 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0259939 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0259209 |
| RPL34 | ribosomal protein L34 | -0.0252084 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0249045 |
| CALR | calreticulin | -0.0247424 |
| MSI2 | musashi RNA-binding protein 2 | -0.0234392 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0233138 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0231695 |
| RPS20 | ribosomal protein S20 | -0.0231271 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | -0.0228402 |
| H1-0 | H1.0 linker histone | -0.0222111 |
| HLA-A | major histocompatibility complex, class I, A | -0.0221093 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0218576 |
| BPTF | bromodomain PHD finger transcription factor | -0.021367 |
| FOXP1 | forkhead box P1 | -0.0212473 |
| ZNRF3 | zinc and ring finger 3 | -0.0211847 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0210635 |
| RPL9 | ribosomal protein L9 | -0.020943 |
| NEBL | nebulette | -0.0209015 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | -0.0204988 |
| PTK2 | protein tyrosine kinase 2 | -0.0201194 |
| RPS16 | ribosomal protein S16 | -0.019684 |
| NUCB2 | nucleobindin 2 | -0.0194402 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0193983 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0190215 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0189219 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0188604 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0183298 |
| NCKAP5 | NCK-associated protein 5 | -0.0183003 |
| IRS2 | insulin receptor substrate 2 | -0.018166 |
| ARF1 | ADP-ribosylation factor 1 | -0.0180111 |
| SIL1 | SIL1 nucleotide exchange factor | -0.0179494 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0179074 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0178533 |
| SEC24D | SEC24 family member D | -0.017851 |
| GNAS | GNAS complex locus | -0.0178355 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0177815 |
| COG5 | component of oligomeric golgi complex 5 | -0.0175147 |
| UTRN | utrophin | -0.0175124 |
| CTSB | cathepsin B | -0.0173751 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0171109 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0170314 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0170088 |
| PMM2 | phosphomannomutase 2 | -0.0170022 |
| GOLGA4 | golgin A4 | -0.0168865 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | -0.0167953 |
| WDR37 | WD repeat domain 37 | -0.0167522 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0167521 |
| SMYD3 | SET and MYND domain containing 3 | -0.0166976 |
| KIZ | kizuna centrosomal protein | -0.0166223 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0165269 |
| RPL12 | ribosomal protein L12 | -0.016233 |
| INTS6 | integrator complex subunit 6 | -0.0162298 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0162158 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0159157 |
| PLSCR1 | phospholipid scramblase 1 | -0.0159063 |
| RPL27A | ribosomal protein L27a | -0.0157611 |
| USPL1 | ubiquitin specific peptidase like 1 | -0.015721 |
| ZNF395 | zinc finger protein 395 | -0.0156271 |
| FBXO16 | F-box protein 16 | -0.0154244 |
| DSTN | destrin (actin depolymerizing factor) | -0.015329 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0152811 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0152061 |
