| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenylephrine (hydrochloride)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.172748 |
| STC1 | stanniocalcin 1 | 0.168024 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.127172 |
| B2M | beta-2-microglobulin | 0.123129 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.102177 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0995979 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0893793 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0822097 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0787097 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0717771 |
| EGFR | epidermal growth factor receptor | 0.0696654 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0695631 |
| VIM | vimentin | 0.0690718 |
| MT2A | metallothionein 2A | 0.0676893 |
| COPA | coatomer protein complex, subunit alpha | 0.0629398 |
| CALR | calreticulin | 0.0627485 |
| ENO1 | enolase 1, (alpha) | 0.0626962 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0622644 |
| PGK1 | phosphoglycerate kinase 1 | 0.0613872 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0575779 |
| COL6A3 | collagen, type VI, alpha 3 | 0.057091 |
| GOLGA4 | golgin A4 | 0.0560337 |
| GPR173 | G protein-coupled receptor 173 | 0.0550889 |
| HDAC9 | histone deacetylase 9 | 0.0515665 |
| HELZ | helicase with zinc finger | 0.0508922 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0508613 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.050709 |
| CANX | calnexin | 0.0495825 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0494418 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0481506 |
| SRP54 | signal recognition particle 54kDa | 0.047706 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0476124 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0473733 |
| MSN | moesin | 0.0463912 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0450681 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0446547 |
| FNIP1 | folliculin interacting protein 1 | 0.0445481 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0442894 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0439946 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0433528 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 0.0428344 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0416108 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0412682 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0408889 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0387826 |
| MMP12 | matrix metallopeptidase 12 | 0.0371559 |
| TXNIP | thioredoxin interacting protein | 0.0371298 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0363369 |
| NOP58 | NOP58 ribonucleoprotein | 0.0361392 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0358494 |
| SPAG9 | sperm associated antigen 9 | 0.0353067 |
| NDRG1 | N-myc downstream regulated 1 | 0.0352349 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0350478 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0344816 |
| DTNA | dystrobrevin, alpha | 0.0342856 |
| MYO1B | myosin IB | 0.034146 |
| ATP13A3 | ATPase type 13A3 | 0.0341193 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.033735 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.033439 |
| ZNF395 | zinc finger protein 395 | 0.0331556 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0329328 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0326754 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0323706 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0322592 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.032048 |
| ZNF160 | zinc finger protein 160 | 0.0320275 |
| VMP1 | vacuole membrane protein 1 | 0.0318391 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.031111 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.030883 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0306441 |
| MYOF | myoferlin | 0.0303197 |
| INSIG2 | insulin induced gene 2 | 0.0302 |
| PAPOLA | poly(A) polymerase alpha | 0.0301593 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0298131 |
| POM121 | POM121 transmembrane nucleoporin | 0.0295401 |
| MT1X | metallothionein 1X | 0.0295279 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0294325 |
| FAM219A | family with sequence similarity 219, member A | 0.029398 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0293613 |
| ZNF451 | zinc finger protein 451 | 0.0293398 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0292256 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.029154 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0291219 |
| ZNF292 | zinc finger protein 292 | 0.0289394 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | 0.028584 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0285139 |
| FAM13A | family with sequence similarity 13, member A | 0.0279693 |
| TPM3 | tropomyosin 3 | 0.0278975 |
| COG5 | component of oligomeric golgi complex 5 | 0.0278411 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0277369 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0277001 |
| PYGL | phosphorylase, glycogen, liver | 0.0274442 |
| FAF2 | Fas associated factor family member 2 | 0.0273476 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0272237 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0272193 |
| POM121C | POM121 transmembrane nucleoporin C | 0.026873 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0268466 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.026744 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0266012 |
| CALU | calumenin | 0.026595 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.115233 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.101737 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0816754 |
| MAP1B | microtubule-associated protein 1B | -0.0810176 |
| TXNRD1 | thioredoxin reductase 1 | -0.0761095 |
| ATXN1 | ataxin 1 | -0.0662856 |
| STK17A | serine/threonine kinase 17a | -0.0578123 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0537898 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0501309 |
| GLIS3 | GLIS family zinc finger 3 | -0.0491739 |
| FLNA | filamin A, alpha | -0.048081 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0423436 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0411937 |
| RPLP1 | ribosomal protein, large, P1 | -0.0404771 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0386817 |
| EXOC4 | exocyst complex component 4 | -0.0375492 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0370406 |
| AHR | aryl hydrocarbon receptor | -0.0370172 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0369722 |
| LDHA | lactate dehydrogenase A | -0.0369619 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0350115 |
| NAV2 | neuron navigator 2 | -0.0345689 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0343902 |
| SQSTM1 | sequestosome 1 | -0.0343368 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.034315 |
| RPS24 | ribosomal protein S24 | -0.0340813 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0340302 |
| TMSB10 | thymosin beta 10 | -0.0331367 |
| NLGN1 | neuroligin 1 | -0.0325788 |
| RPL35A | ribosomal protein L35a | -0.0324549 |
| ANXA2 | annexin A2 | -0.0322214 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0316754 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0312849 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.031144 |
| FUS | FUS RNA binding protein | -0.0308414 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0305389 |
| RPL34 | ribosomal protein L34 | -0.0297977 |
| CD44 | CD44 molecule (Indian blood group) | -0.0295522 |
| RPL38 | ribosomal protein L38 | -0.029369 |
| OSMR | oncostatin M receptor | -0.0289444 |
| AUTS2 | autism susceptibility candidate 2 | -0.0288723 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0287642 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0283371 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0280617 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0278546 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0274485 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0273784 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0269021 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0267909 |
| RRBP1 | ribosome binding protein 1 | -0.0267583 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0266932 |
| TNNC1 | troponin C type 1 (slow) | -0.0266531 |
| RPL28 | ribosomal protein L28 | -0.026651 |
| TUSC3 | tumor suppressor candidate 3 | -0.0262807 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0261538 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.025884 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0253744 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0252797 |
| RPS8 | ribosomal protein S8 | -0.0251538 |
| AAK1 | AP2 associated kinase 1 | -0.0249072 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0247415 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.024732 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0246409 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0246158 |
| RPL9 | ribosomal protein L9 | -0.0245521 |
| VCL | vinculin | -0.0244159 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.024057 |
| AFAP1 | actin filament associated protein 1 | -0.0239831 |
| IL6ST | interleukin 6 signal transducer | -0.0238962 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0238253 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0236565 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0234732 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0233601 |
| RPL27A | ribosomal protein L27a | -0.0233184 |
| ETV6 | ets variant 6 | -0.0232567 |
| CAB39 | calcium binding protein 39 | -0.0231148 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0228977 |
| CTBP2 | C-terminal binding protein 2 | -0.0228517 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0226798 |
| WDR1 | WD repeat domain 1 | -0.0225842 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0224302 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0223697 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0222865 |
| ASPH | aspartate beta-hydroxylase | -0.0222666 |
| RYK | receptor-like tyrosine kinase | -0.0222654 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0219971 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0218719 |
| TJP1 | tight junction protein 1 | -0.0217916 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0217872 |
| TNPO1 | transportin 1 | -0.0217557 |
| RNF213 | ring finger protein 213 | -0.0217478 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0215815 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0215576 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0213944 |
| PLEC | plectin | -0.0212767 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0211881 |
| YBX1 | Y box binding protein 1 | -0.021033 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.0209556 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0206569 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.020593 |
