| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenylephrine (hydrochloride)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.128761 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.114019 |
| GOLGA4 | golgin A4 | 0.108805 |
| ARF4 | ADP-ribosylation factor 4 | 0.0764476 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0752897 |
| TXNRD1 | thioredoxin reductase 1 | 0.0712574 |
| TPM4 | tropomyosin 4 | 0.0697025 |
| AHNAK | AHNAK nucleoprotein | 0.0669813 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0652838 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0641004 |
| TMEM41B | transmembrane protein 41B | 0.0611164 |
| ENO1 | enolase 1, (alpha) | 0.0601943 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0590381 |
| OGA | O-GlcNAcase | 0.0555313 |
| NUP58 | nucleoporin 58 | 0.0553751 |
| FDPS | farnesyl diphosphate synthase | 0.0540563 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0532491 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0525253 |
| ZNF292 | zinc finger protein 292 | 0.0517752 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0514773 |
| VMP1 | vacuole membrane protein 1 | 0.0513752 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0511865 |
| ZNF638 | zinc finger protein 638 | 0.0501699 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0500485 |
| DSPP | dentin sialophosphoprotein | 0.0496847 |
| SUCO | SUN domain containing ossification factor | 0.049594 |
| YME1L1 | YME1-like 1 ATPase | 0.0495644 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0481966 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.04758 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.046991 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0463954 |
| HELZ | helicase with zinc finger | 0.0463362 |
| SQSTM1 | sequestosome 1 | 0.0455751 |
| RBM25 | RNA binding motif protein 25 | 0.0445543 |
| USP34 | ubiquitin specific peptidase 34 | 0.0443525 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0441534 |
| SRP54 | signal recognition particle 54kDa | 0.0439155 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0435796 |
| RAB18 | RAB18, member RAS oncogene family | 0.0435241 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0418696 |
| RBM39 | RNA binding motif protein 39 | 0.0410349 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0410275 |
| PGK1 | phosphoglycerate kinase 1 | 0.0406763 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.039937 |
| INSIG2 | insulin induced gene 2 | 0.0397164 |
| SEC24A | SEC24 family member A | 0.0393389 |
| MT2A | metallothionein 2A | 0.0392442 |
| SET | SET nuclear proto-oncogene | 0.0392325 |
| PAPOLA | poly(A) polymerase alpha | 0.0384704 |
| CENPF | centromere protein F, 350/400kDa | 0.0376432 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0374693 |
| GOLGB1 | golgin B1 | 0.0373083 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.03718 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.037147 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0371113 |
| RNF24 | ring finger protein 24 | 0.0367302 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0366996 |
| ZNF654 | zinc finger protein 654 | 0.0364398 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0363154 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0359051 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0359019 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0354757 |
| TPM3 | tropomyosin 3 | 0.035197 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.035131 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0349047 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0347827 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.034493 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0344413 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0343827 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0343032 |
| KLF6 | Kruppel-like factor 6 | 0.0341666 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0340644 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | 0.0338438 |
| KIAA1217 | KIAA1217 | 0.0332377 |
| FTL | ferritin, light polypeptide | 0.03306 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0328527 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0324265 |
| MCL1 | myeloid cell leukemia 1 | 0.0320548 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0317828 |
| EP300 | E1A binding protein p300 | 0.03151 |
| ZNF451 | zinc finger protein 451 | 0.0315054 |
| YEATS2 | YEATS domain containing 2 | 0.0312487 |
| EZR | ezrin | 0.0311297 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0310818 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0310082 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0309473 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0308774 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0306662 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0304234 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0303556 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0303107 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.030207 |
| SETD5 | SET domain containing 5 | 0.0298268 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0297569 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0297416 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0295295 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0293672 |
| WASHC4 | WASH complex subunit 4 | 0.0293667 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0293488 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0292917 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.148306 |
| FAT1 | FAT atypical cadherin 1 | -0.108048 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.10175 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0901247 |
| TMSB10 | thymosin beta 10 | -0.089546 |
| PTMA | prothymosin, alpha | -0.0806378 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.067287 |
| RPL35A | ribosomal protein L35a | -0.0506945 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.048013 |
| MSI2 | musashi RNA-binding protein 2 | -0.0472724 |
| RPLP1 | ribosomal protein, large, P1 | -0.0471029 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0467094 |
| FHIT | fragile histidine triad | -0.0466233 |
| TENM3 | teneurin transmembrane protein 3 | -0.043571 |
| INTS6 | integrator complex subunit 6 | -0.0435605 |
| WWOX | WW domain containing oxidoreductase | -0.041685 |
| ZNRF3 | zinc and ring finger 3 | -0.0398501 |
| HOXB3 | homeobox B3 | -0.0393169 |
| SMYD3 | SET and MYND domain containing 3 | -0.0372017 |
| FUS | FUS RNA binding protein | -0.0364165 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0361273 |
| RAD51B | RAD51 paralog B | -0.0352592 |
| LRRC23 | leucine rich repeat containing 23 | -0.0341514 |
| RPS24 | ribosomal protein S24 | -0.0340371 |
| FLNA | filamin A, alpha | -0.0329371 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0324636 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0313822 |
| SERINC5 | serine incorporator 5 | -0.0302292 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0300008 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0298761 |
| CADPS | Ca++-dependent secretion activator | -0.0293603 |
| TGFB1 | transforming growth factor, beta 1 | -0.0282805 |
| RPS6 | ribosomal protein S6 | -0.0280257 |
| SUMF1 | sulfatase modifying factor 1 | -0.0279637 |
| S100A10 | S100 calcium binding protein A10 | -0.0266347 |
| NFIA | nuclear factor I/A | -0.0263759 |
| RNF43 | ring finger protein 43 | -0.0262159 |
| RPL38 | ribosomal protein L38 | -0.0257846 |
| FRMD5 | FERM domain containing 5 | -0.0254602 |
| ACTG1 | actin gamma 1 | -0.0252354 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0251389 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0251303 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0247409 |
| HDLBP | high density lipoprotein binding protein | -0.0233005 |
| LASP1 | LIM and SH3 protein 1 | -0.0231956 |
| RPLP0 | ribosomal protein, large, P0 | -0.0230623 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0228634 |
| RPL30 | ribosomal protein L30 | -0.0227743 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.021987 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0219191 |
| HMGB1 | high mobility group box 1 | -0.0218005 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0216175 |
| CTBP2 | C-terminal binding protein 2 | -0.0214824 |
| RPS13 | ribosomal protein S13 | -0.0213888 |
| RPLP2 | ribosomal protein, large, P2 | -0.0212298 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0210493 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0209258 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0208965 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0206619 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0205495 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0204385 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0203684 |
| PRDM2 | PR domain containing 2, with ZNF domain | -0.0202574 |
| RCC1 | regulator of chromosome condensation 1 | -0.0202105 |
| RPS20 | ribosomal protein S20 | -0.02019 |
| ARF1 | ADP-ribosylation factor 1 | -0.0201253 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0200068 |
| HELLS | helicase, lymphoid-specific | -0.0199661 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.019832 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0197302 |
| CALR | calreticulin | -0.0196282 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0191386 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0190062 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0190015 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0189042 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0188424 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0187264 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0187206 |
| ZNF37A | zinc finger protein 37A | -0.0186275 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0185514 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0185343 |
| MAP4 | microtubule-associated protein 4 | -0.0185281 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0184224 |
| AIG1 | androgen-induced 1 | -0.0183898 |
| HMGA2 | high mobility group AT-hook 2 | -0.0182254 |
| CFAP44 | cilia and flagella associated protein 44 | -0.0181734 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0178746 |
| PARD3 | par-3 family cell polarity regulator | -0.0174958 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0174571 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | -0.0173997 |
| LDHA | lactate dehydrogenase A | -0.0173732 |
| CCND1 | cyclin D1 | -0.0172177 |
| ELOVL6 | ELOVL fatty acid elongase 6 | -0.0172094 |
| H1-0 | H1.0 linker histone | -0.0170568 |
| LMNA | lamin A/C | -0.0169826 |
| RPL28 | ribosomal protein L28 | -0.0168674 |
| CFAP97 | cilia and flagella associated protein 97 | -0.016707 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0162268 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0161933 |
| PLCB4 | phospholipase C, beta 4 | -0.016161 |
