| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Phenylephrine (hydrochloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Phenylephrine (hydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0962692 |
| NDRG1 | N-myc downstream regulated 1 | 0.0840628 |
| GOLGA4 | golgin A4 | 0.0714033 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0685281 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0583747 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0561354 |
| FAM13A | family with sequence similarity 13, member A | 0.0538748 |
| FTL | ferritin, light polypeptide | 0.0494639 |
| RPS3 | ribosomal protein S3 | 0.0480955 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0472628 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0467058 |
| RPS2 | ribosomal protein S2 | 0.0454576 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.045068 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0427854 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0392396 |
| B2M | beta-2-microglobulin | 0.0369646 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0364584 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0355479 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0350047 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0346143 |
| ZNF292 | zinc finger protein 292 | 0.0340766 |
| RPS8 | ribosomal protein S8 | 0.0339107 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0338699 |
| ENO1 | enolase 1, (alpha) | 0.0327323 |
| RPS12 | ribosomal protein S12 | 0.032547 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.031642 |
| RPL21 | ribosomal protein L21 | 0.0309748 |
| OGA | O-GlcNAcase | 0.0308796 |
| HYOU1 | hypoxia up-regulated 1 | 0.0303467 |
| HELZ | helicase with zinc finger | 0.0303069 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0302536 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0300316 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0298741 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0295412 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.029533 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0290587 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0290062 |
| VEGFA | vascular endothelial growth factor A | 0.0289615 |
| CCNY | cyclin Y | 0.0282828 |
| RPS6 | ribosomal protein S6 | 0.0277658 |
| KIF5B | kinesin family member 5B | 0.0269716 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0267974 |
| CALR | calreticulin | 0.0262333 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0262249 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0261035 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0260372 |
| FBXO32 | F-box protein 32 | 0.0258224 |
| RPS19 | ribosomal protein S19 | 0.0258135 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0256809 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0256066 |
| RPL23 | ribosomal protein L23 | 0.025349 |
| SET | SET nuclear proto-oncogene | 0.0253489 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0249672 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0248051 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0246169 |
| NUP58 | nucleoporin 58 | 0.0244181 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0242064 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0241898 |
| SUCO | SUN domain containing ossification factor | 0.02389 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0236555 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0236343 |
| RPL18 | ribosomal protein L18 | 0.0235679 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0233047 |
| CANX | calnexin | 0.0232341 |
| RNF145 | ring finger protein 145 | 0.0231934 |
| RPLP1 | ribosomal protein, large, P1 | 0.0224681 |
| PGK1 | phosphoglycerate kinase 1 | 0.0224676 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0221278 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0220181 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.021659 |
| MORF4L2 | mortality factor 4 like 2 | 0.0216073 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0215206 |
| SRP54 | signal recognition particle 54kDa | 0.0214582 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0214086 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0214048 |
| RPS13 | ribosomal protein S13 | 0.0213591 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0211599 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0208426 |
| CREBRF | CREB3 regulatory factor | 0.0208409 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0207624 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0206235 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0201717 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0200743 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0200596 |
| RPS25 | ribosomal protein S25 | 0.0199903 |
| INSIG2 | insulin induced gene 2 | 0.0199416 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.019566 |
| ZNF638 | zinc finger protein 638 | 0.0194645 |
| RPS17 | ribosomal protein S17 | 0.0194319 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0192406 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0189758 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0189068 |
| KLHL24 | kelch-like family member 24 | 0.0188998 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0187582 |
| FNIP1 | folliculin interacting protein 1 | 0.0187068 |
| CDK8 | cyclin-dependent kinase 8 | 0.0186344 |
| RPL31 | ribosomal protein L31 | 0.0184212 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0183831 |
| ATXN2 | ataxin 2 | 0.0182712 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0181915 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.091643 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0912325 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0821886 |
| ACTN4 | actinin, alpha 4 | -0.0758647 |
| LMO7 | LIM domain 7 | -0.0754383 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0745273 |
| KRT8 | keratin 8, type II | -0.0724861 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0703264 |
| SMAD3 | SMAD family member 3 | -0.0676447 |
| KRT18 | keratin 18, type I | -0.0667202 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0647821 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0639691 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0612036 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.058448 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0568724 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0568516 |
| LAMA4 | laminin, alpha 4 | -0.0560253 |
| BCL2L1 | BCL2-like 1 | -0.0543376 |
| WWC1 | WW and C2 domain containing 1 | -0.0541998 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0507896 |
| STK24 | serine/threonine kinase 24 | -0.0504999 |
| ANXA2 | annexin A2 | -0.0495215 |
| MYO1E | myosin IE | -0.0468453 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0467625 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0446595 |
| SEPTIN9 | septin 9 | -0.0437805 |
| KRT20 | keratin 20, type I | -0.0428943 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0423235 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0416845 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0414787 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0411325 |
| VCL | vinculin | -0.0410966 |
| TJP1 | tight junction protein 1 | -0.0409064 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.040214 |
| TRIB1 | tribbles pseudokinase 1 | -0.0400067 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0394434 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0393041 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0387972 |
| ACTG1 | actin gamma 1 | -0.0387086 |
| NTN4 | netrin 4 | -0.0381112 |
| FLNB | filamin B, beta | -0.0371762 |
| TMSB10 | thymosin beta 10 | -0.0368578 |
| EXOC4 | exocyst complex component 4 | -0.0362591 |
| EZR | ezrin | -0.0356434 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0351868 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0349797 |
| TXNRD1 | thioredoxin reductase 1 | -0.0344182 |
| EGR1 | early growth response 1 | -0.0335121 |
| LMNA | lamin A/C | -0.0334927 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0329767 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0316855 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0315954 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0314526 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0312416 |
| KIAA0232 | KIAA0232 | -0.0310242 |
| ETV6 | ets variant 6 | -0.0309569 |
| ARHGAP23 | Rho GTPase activating protein 23 | -0.0305708 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0303678 |
| NF1 | neurofibromin 1 | -0.0294828 |
| KLK10 | kallikrein-related peptidase 10 | -0.0293284 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0293261 |
| CAPN8 | calpain 8 | -0.0291441 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0290703 |
| JUN | jun proto-oncogene | -0.0290623 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0289175 |
| ABLIM1 | actin binding LIM protein 1 | -0.028648 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0285194 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0283645 |
| DIAPH2 | diaphanous-related formin 2 | -0.0282268 |
| AHNAK | AHNAK nucleoprotein | -0.028124 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0278278 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0276496 |
| SULF2 | sulfatase 2 | -0.027369 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0272445 |
| RNF213 | ring finger protein 213 | -0.0269871 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0265743 |
| LATS2 | large tumor suppressor kinase 2 | -0.0263602 |
| CD2AP | CD2-associated protein | -0.026321 |
| FOXO1 | forkhead box O1 | -0.0262108 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0261808 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0260841 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0259774 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0258183 |
| SDC4 | syndecan 4 | -0.0254032 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0250084 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0248288 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0243639 |
| CTBP2 | C-terminal binding protein 2 | -0.0243626 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | -0.0241306 |
| ANXA11 | annexin A11 | -0.0240337 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.023596 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0235874 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0235715 |
| PYGB | phosphorylase, glycogen; brain | -0.0232821 |
| DGKH | diacylglycerol kinase, eta | -0.0229756 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0228498 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.022629 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0222852 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0222107 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0219221 |
